JP2021511299A5 - - Google Patents
Info
- Publication number
- JP2021511299A5 JP2021511299A5 JP2020538535A JP2020538535A JP2021511299A5 JP 2021511299 A5 JP2021511299 A5 JP 2021511299A5 JP 2020538535 A JP2020538535 A JP 2020538535A JP 2020538535 A JP2020538535 A JP 2020538535A JP 2021511299 A5 JP2021511299 A5 JP 2021511299A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- salt
- membered heteroaryl
- heteroaryl ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023162922A JP7744955B2 (ja) | 2018-01-10 | 2023-09-26 | 可溶性グアニル酸シクラーゼ刺激剤を調製するための新規のプロセスおよび中間体 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862615678P | 2018-01-10 | 2018-01-10 | |
| US62/615,678 | 2018-01-10 | ||
| CNPCT/CN2018/076982 | 2018-02-22 | ||
| PCT/CN2018/076982 WO2019161534A1 (en) | 2018-02-22 | 2018-02-22 | Novel processes and intermediates for preparation of soluble guanylate cyclase stimulators |
| PCT/US2019/013060 WO2019140095A1 (en) | 2018-01-10 | 2019-01-10 | Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023162922A Division JP7744955B2 (ja) | 2018-01-10 | 2023-09-26 | 可溶性グアニル酸シクラーゼ刺激剤を調製するための新規のプロセスおよび中間体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021511299A JP2021511299A (ja) | 2021-05-06 |
| JP2021511299A5 true JP2021511299A5 (enExample) | 2022-01-19 |
| JP7357621B2 JP7357621B2 (ja) | 2023-10-06 |
Family
ID=65279655
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020538535A Active JP7357621B2 (ja) | 2018-01-10 | 2019-01-10 | 可溶性グアニル酸シクラーゼ刺激剤を調製するための新規のプロセスおよび中間体 |
| JP2023162922A Active JP7744955B2 (ja) | 2018-01-10 | 2023-09-26 | 可溶性グアニル酸シクラーゼ刺激剤を調製するための新規のプロセスおよび中間体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023162922A Active JP7744955B2 (ja) | 2018-01-10 | 2023-09-26 | 可溶性グアニル酸シクラーゼ刺激剤を調製するための新規のプロセスおよび中間体 |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US11274096B2 (enExample) |
| EP (3) | EP4570797A3 (enExample) |
| JP (2) | JP7357621B2 (enExample) |
| KR (3) | KR20250002720A (enExample) |
| CN (3) | CN118184645A (enExample) |
| AU (3) | AU2019206560B2 (enExample) |
| BR (1) | BR112020013985A2 (enExample) |
| CA (1) | CA3087943A1 (enExample) |
| CL (3) | CL2020001814A1 (enExample) |
| ES (1) | ES2963447T3 (enExample) |
| IL (3) | IL314714A (enExample) |
| JO (1) | JOP20200165A1 (enExample) |
| MA (2) | MA71753A (enExample) |
| MX (3) | MX2020007364A (enExample) |
| SG (1) | SG11202006311SA (enExample) |
| TW (2) | TWI888947B (enExample) |
| WO (1) | WO2019140095A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109563077B (zh) | 2016-07-07 | 2026-03-10 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的新方法 |
| US11274096B2 (en) | 2018-01-10 | 2022-03-15 | Cyclerion Therapeutics, Inc. | Processes and intermediates for the preparation of soluble guanylate cyclase stimulators |
| CN118221651A (zh) * | 2022-12-21 | 2024-06-21 | 广东东阳光药业股份有限公司 | 氟取代的吲唑化合物的晶型及其用途 |
| AU2023412228A1 (en) * | 2022-12-21 | 2025-07-03 | Sunshine Lake Pharma Co., Ltd. | Crystal form of fluorine-substituted indazole compound and use thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2588465B1 (en) * | 2010-06-30 | 2017-01-25 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| EA033168B1 (ru) * | 2013-03-15 | 2019-09-30 | Сайклерион Терапьютикс, Инк. | СТИМУЛЯТОРЫ sGC |
| EP3094327A1 (en) * | 2014-01-13 | 2016-11-23 | Ironwood Pharmaceuticals, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS |
| EP3194382B1 (en) | 2014-09-17 | 2021-09-08 | Cyclerion Therapeutics, Inc. | Pyrazole derivatives as sgc stimulators |
| EA201790627A1 (ru) * | 2014-09-17 | 2017-09-29 | Айронвуд Фармасьютикалз, Инк. | СТИМУЛЯТОРЫ рГЦ |
| CA3006746C (en) | 2015-11-30 | 2024-01-30 | Ironwood Pharmaceuticals, Inc. | Solid dispersions comprising a sgc stimulator |
| CN109563086B (zh) | 2016-07-07 | 2023-05-23 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的方法 |
| CN109563077B (zh) | 2016-07-07 | 2026-03-10 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的新方法 |
| US11274096B2 (en) | 2018-01-10 | 2022-03-15 | Cyclerion Therapeutics, Inc. | Processes and intermediates for the preparation of soluble guanylate cyclase stimulators |
-
2019
- 2019-01-10 US US16/961,109 patent/US11274096B2/en active Active
- 2019-01-10 IL IL314714A patent/IL314714A/en unknown
- 2019-01-10 CN CN202410363182.2A patent/CN118184645A/zh active Pending
- 2019-01-10 KR KR1020247039985A patent/KR20250002720A/ko active Pending
- 2019-01-10 EP EP25174051.0A patent/EP4570797A3/en active Pending
- 2019-01-10 TW TW112138274A patent/TWI888947B/zh active
- 2019-01-10 CA CA3087943A patent/CA3087943A1/en active Pending
- 2019-01-10 SG SG11202006311SA patent/SG11202006311SA/en unknown
- 2019-01-10 WO PCT/US2019/013060 patent/WO2019140095A1/en not_active Ceased
- 2019-01-10 MA MA71753A patent/MA71753A/fr unknown
- 2019-01-10 AU AU2019206560A patent/AU2019206560B2/en active Active
- 2019-01-10 MA MA051565A patent/MA51565A/fr unknown
- 2019-01-10 TW TW108101044A patent/TWI821237B/zh active
- 2019-01-10 IL IL319883A patent/IL319883A/en unknown
- 2019-01-10 KR KR1020257010603A patent/KR20250048609A/ko active Pending
- 2019-01-10 CN CN202410363184.1A patent/CN118221665A/zh active Pending
- 2019-01-10 BR BR112020013985-8A patent/BR112020013985A2/pt active IP Right Grant
- 2019-01-10 ES ES19703440T patent/ES2963447T3/es active Active
- 2019-01-10 JO JOP/2020/0165A patent/JOP20200165A1/ar unknown
- 2019-01-10 EP EP19703440.8A patent/EP3737679B1/en active Active
- 2019-01-10 EP EP23187776.2A patent/EP4249469A3/en active Pending
- 2019-01-10 JP JP2020538535A patent/JP7357621B2/ja active Active
- 2019-01-10 KR KR1020207022640A patent/KR102739727B1/ko active Active
- 2019-01-10 MX MX2020007364A patent/MX2020007364A/es unknown
- 2019-01-10 IL IL275748A patent/IL275748B2/en unknown
- 2019-01-10 CN CN201980017700.2A patent/CN111902410B/zh active Active
-
2020
- 2020-07-07 CL CL2020001814A patent/CL2020001814A1/es unknown
- 2020-07-13 MX MX2023000045A patent/MX2023000045A/es unknown
- 2020-07-13 MX MX2023000044A patent/MX2023000044A/es unknown
-
2021
- 2021-10-08 US US17/497,352 patent/US11708361B2/en active Active
-
2022
- 2022-04-08 CL CL2022000907A patent/CL2022000907A1/es unknown
- 2022-04-08 CL CL2022000904A patent/CL2022000904A1/es unknown
-
2023
- 2023-04-28 US US18/140,966 patent/US12030874B2/en active Active
- 2023-09-26 JP JP2023162922A patent/JP7744955B2/ja active Active
- 2023-11-22 AU AU2023270260A patent/AU2023270260B2/en active Active
-
2024
- 2024-05-22 US US18/671,182 patent/US12275724B2/en active Active
-
2025
- 2025-03-31 AU AU2025202281A patent/AU2025202281A1/en active Pending
- 2025-04-11 US US19/176,742 patent/US20250361228A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI659016B (zh) | 製備經取代之５-氟-１ｈ-吡唑并吡啶類之中間體的方法 | |
| TWI453202B (zh) | 製備拉帕替尼之方法及中間體 | |
| CA2698245C (en) | Process and intermediates for preparing integrase inhibitors | |
| EP2069280B1 (en) | Process and intermediates for preparing HIV integrase inhibitors | |
| WO2021147894A1 (zh) | 草铵膦的制备方法 | |
| JP2021511299A5 (enExample) | ||
| CN111362881A (zh) | 一种化合物及其制备方法 | |
| JP2014516072A (ja) | アピキサバン製造方法 | |
| MX2011007445A (es) | Proceso para la elaboracion y resolucion del acido 2-acil-amino-3-difenil-propionico. | |
| AU2017364725B2 (en) | Method for producing triazolopyridine compound | |
| CN111295381A (zh) | 可用于合成抗蛋白激酶的选择性抑制剂的中间体及其制备方法 | |
| TW202210486A (zh) | 一種製備ｇｌｐ—１受體激動劑的方法 | |
| KR20090083455A (ko) | 이마티닙 및 그들의 중간체 및 그 제조방법 | |
| TWI888947B (zh) | 用於製備可溶性鳥苷酸環化酶刺激劑之新穎方法及中間物 | |
| JP7205529B2 (ja) | オキサゾリジノン化合物の製造方法 | |
| CN121362189A (zh) | 吉泊达星的中间体及其制备方法和吉泊达星的制备方法 | |
| TW202239409A (zh) | 化合物 | |
| US10851087B2 (en) | Synthesis of cerdulatinib | |
| WO2012027951A1 (zh) | 一种合成培南类药物的中间体及其制备方法和应用 | |
| TWI844663B (zh) | 製造經取代之2-[2-(苯基)乙胺]烷醯胺衍生物之方法 | |
| TW201504215A (zh) | 嗒□化合物之製造方法 | |
| TWI845992B (zh) | 一種ｂ肝病毒核衣殼抑制劑的製備方法 | |
| KR20220107602A (ko) | 5-치환된 테트라졸의 신규 제조방법 | |
| TWI915494B (zh) | 製備富含鏡像異構型態的3-(2-氯噻唑-5-基)-8-甲基-7-氧代-6-苯基-2,3-二氫噻唑并[3,2-a]嘧啶-4-鎓-5-醇鹽的方法 | |
| JP2021524500A (ja) | ジアミノピリミジン誘導体またはその酸付加塩の新規な製造方法 |