JP2021502813A5 - - Google Patents
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- JP2021502813A5 JP2021502813A5 JP2020526394A JP2020526394A JP2021502813A5 JP 2021502813 A5 JP2021502813 A5 JP 2021502813A5 JP 2020526394 A JP2020526394 A JP 2020526394A JP 2020526394 A JP2020526394 A JP 2020526394A JP 2021502813 A5 JP2021502813 A5 JP 2021502813A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid sequence
- seq
- acid molecule
- isolated nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023025663A JP2023075139A (ja) | 2017-11-15 | 2023-02-22 | 霊長類網膜色素上皮細胞特異的プロモーター |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17201828.5 | 2017-11-15 | ||
| EP17201828 | 2017-11-15 | ||
| PCT/IB2018/059015 WO2019097454A1 (en) | 2017-11-15 | 2018-11-15 | Primate retinal pigment epithelium cell-specific promoter |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023025663A Division JP2023075139A (ja) | 2017-11-15 | 2023-02-22 | 霊長類網膜色素上皮細胞特異的プロモーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021502813A JP2021502813A (ja) | 2021-02-04 |
| JP2021502813A5 true JP2021502813A5 (https=) | 2021-12-23 |
| JP7348176B2 JP7348176B2 (ja) | 2023-09-20 |
Family
ID=60331462
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526394A Active JP7348176B2 (ja) | 2017-11-15 | 2018-11-15 | 霊長類網膜色素上皮細胞特異的プロモーター |
| JP2023025663A Pending JP2023075139A (ja) | 2017-11-15 | 2023-02-22 | 霊長類網膜色素上皮細胞特異的プロモーター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023025663A Pending JP2023075139A (ja) | 2017-11-15 | 2023-02-22 | 霊長類網膜色素上皮細胞特異的プロモーター |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11739349B2 (https=) |
| EP (1) | EP3709798B1 (https=) |
| JP (2) | JP7348176B2 (https=) |
| KR (1) | KR20200084028A (https=) |
| CN (1) | CN111726985B (https=) |
| AU (1) | AU2018369975B2 (https=) |
| BR (1) | BR112020009579A2 (https=) |
| CA (1) | CA3082080A1 (https=) |
| CR (1) | CR20200210A (https=) |
| IL (1) | IL274460A (https=) |
| MX (1) | MX2020005033A (https=) |
| PH (1) | PH12020550757A1 (https=) |
| SG (1) | SG11202004205YA (https=) |
| WO (1) | WO2019097454A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2010011467A (es) | 2008-04-18 | 2011-02-15 | Novartis Forschungsstiftung | Novedosas herramientas y metodos terapeuticos para tratar la ceguera. |
| US10941417B2 (en) | 2015-04-30 | 2021-03-09 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in Müller cells |
| US10857241B2 (en) | 2015-09-15 | 2020-12-08 | Friedrich Miescher Institute For Biomedical Research | Therapeutical tools and methods for treating blindness by targeting photoreceptors |
| WO2017064642A1 (en) | 2015-10-14 | 2017-04-20 | Fredrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in retinal endothelial cells |
| EP3383440B1 (en) | 2015-12-03 | 2021-06-30 | Friedrich Miescher Institute for Biomedical Research | Synp162, a promoter for the specific expression of genes in rod photoreceptors |
| ES2909444T3 (es) | 2015-12-03 | 2022-05-06 | Friedrich Miescher Institute For Biomedical Res | Synp159, un promotor para la expresión específica de genes en los fotorreceptores de los bastones |
| WO2017093934A1 (en) | 2015-12-03 | 2017-06-08 | Friedrich Miescher Institute For Biomedical Research | Synp160, a promoter for the specific expression of genes in rod photoreceptors |
| EP3383439B1 (en) | 2015-12-03 | 2019-09-25 | Friedrich Miescher Institute for Biomedical Research | Synp161, a promoter for the specific expression of genes in rod photoreceptors |
| RU2766353C2 (ru) | 2016-11-02 | 2022-03-15 | Фридрих Мишер Инститьют Фор Байомедикал Рисерч | Synp198, промотор для специфической экспрессии генов в ганглионарных клетках сетчатки, избирательных в отношении направления |
| WO2018146588A1 (en) | 2017-02-08 | 2018-08-16 | Friedrich Miescher Institute For Biomedical Research | Synp88, a promoter for the specific expression of genes in retinal ganglion cells |
| MX2020005033A (es) | 2017-11-15 | 2020-10-28 | Friedrich Miescher Institute For Biomedical Res | Promotor especifico de las celulas del epitelio pigmentario retinal en primates. |
| CN111527102A (zh) * | 2017-11-30 | 2020-08-11 | 弗里德里克·米谢尔生物医学研究所 | 灵长类动物视网膜色素上皮细胞特异性启动子SynP61 |
| SG11202005024QA (en) | 2017-11-30 | 2020-06-29 | Friedrich Miescher Institute For Biomedical Res | Synpiii, a promoter for the specific expression of genes in retinal pigment epithelium |
| CN114045264B (zh) * | 2021-11-16 | 2024-05-14 | 珠海中科先进技术研究院有限公司 | 一种获取驱动元件的方法 |
| EP4568710A1 (en) * | 2022-08-11 | 2025-06-18 | Institute Of Molecular And Clinical Ophthalmology Basel (Iob) | Human cone photoreceptor optogenetic constructs |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582908B2 (en) | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| US5474796A (en) | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| US20020052332A1 (en) | 2000-04-11 | 2002-05-02 | The Board Of Regents, University Of Texas System | Methods of inhibiting retinal pigment epithelial cell degeneration, stable cell lines, and uses |
| US20040208847A1 (en) * | 2003-03-28 | 2004-10-21 | Fabienne Rolling | Method and vectors for selectively transducing retinal pigment epithelium cells |
| EP2929782A1 (en) | 2004-01-23 | 2015-10-14 | Ocata Therapeutics, Inc. | Improved modalities for the treatment of degenerative diseases of the retina |
| US7309487B2 (en) | 2004-02-09 | 2007-12-18 | George Inana | Methods and compositions for detecting and treating retinal diseases |
| EP1891976A1 (en) | 2006-08-23 | 2008-02-27 | Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research | Use of light sensitive genes |
| MX2010011467A (es) | 2008-04-18 | 2011-02-15 | Novartis Forschungsstiftung | Novedosas herramientas y metodos terapeuticos para tratar la ceguera. |
| WO2009134681A2 (en) * | 2008-04-30 | 2009-11-05 | The Trustees Of The University Of Pennsylvania | Aav7 viral vectors for targeted delivery of rpe cells |
| CN101747425B (zh) | 2008-12-16 | 2012-03-28 | 清华大学 | 与视网膜光反应相关的蛋白及其编码基因与应用 |
| US20120172419A1 (en) * | 2009-09-15 | 2012-07-05 | Medical College Of Wisconsin Research Foundation Inc. | Reagents and methods for modulating cone photoreceptor activity |
| KR20130010121A (ko) | 2010-03-23 | 2013-01-25 | 인트렉손 코포레이션 | 치료적 단백질을 조건부로 발현하는 벡터，상기 벡터를 포함하는 숙주 세포 및 이의 용도 |
| WO2012051599A2 (en) * | 2010-10-15 | 2012-04-19 | Eos Neuroscience, Inc. | Modulation neural pathways |
| WO2014033095A1 (en) | 2012-08-27 | 2014-03-06 | Friedrich Miescher Institute For Biomedical Research | Retinal off circuit-specific promoter |
| EP3104895A1 (en) * | 2014-02-10 | 2016-12-21 | Friedrich Miescher Institute for Biomedical Research | Aii retinal amacrine cell-specific promoter |
| EP3105334B1 (en) | 2014-02-11 | 2019-07-03 | Friedrich Miescher Institute for Biomedical Research | Müller cell-specific promoter |
| LT3137497T (lt) * | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| US10941417B2 (en) | 2015-04-30 | 2021-03-09 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in Müller cells |
| US10857241B2 (en) | 2015-09-15 | 2020-12-08 | Friedrich Miescher Institute For Biomedical Research | Therapeutical tools and methods for treating blindness by targeting photoreceptors |
| WO2017064642A1 (en) | 2015-10-14 | 2017-04-20 | Fredrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in retinal endothelial cells |
| ES2909444T3 (es) | 2015-12-03 | 2022-05-06 | Friedrich Miescher Institute For Biomedical Res | Synp159, un promotor para la expresión específica de genes en los fotorreceptores de los bastones |
| WO2017093934A1 (en) | 2015-12-03 | 2017-06-08 | Friedrich Miescher Institute For Biomedical Research | Synp160, a promoter for the specific expression of genes in rod photoreceptors |
| EP3383439B1 (en) | 2015-12-03 | 2019-09-25 | Friedrich Miescher Institute for Biomedical Research | Synp161, a promoter for the specific expression of genes in rod photoreceptors |
| EP3383440B1 (en) | 2015-12-03 | 2021-06-30 | Friedrich Miescher Institute for Biomedical Research | Synp162, a promoter for the specific expression of genes in rod photoreceptors |
| WO2017093566A1 (en) | 2015-12-04 | 2017-06-08 | Universite Pierre Et Marie Curie (Paris 6) | Promoters and uses thereof |
| CN107287238B (zh) | 2016-04-11 | 2020-10-16 | 厦门继景生物技术有限责任公司 | 一种基因载体及其用于治疗雷柏氏先天性黑矇2型疾病的基因治疗药物 |
| US20190209708A1 (en) | 2016-05-17 | 2019-07-11 | Friedrich Miescher Institute For Biomedical Research | Novel therapeutic tools and methods for treating blindness |
| RU2766353C2 (ru) | 2016-11-02 | 2022-03-15 | Фридрих Мишер Инститьют Фор Байомедикал Рисерч | Synp198, промотор для специфической экспрессии генов в ганглионарных клетках сетчатки, избирательных в отношении направления |
| US20190376083A1 (en) | 2016-12-01 | 2019-12-12 | Friedrich Miescher Institute For Biomedical Research | Synp1, a promoter for the specific expression of genes in interneurons |
| EP3548093A1 (en) | 2016-12-01 | 2019-10-09 | Friedrich Miescher Institute for Biomedical Research | Synp107, a promoter for the specific expression of genes in interneurons |
| WO2018146588A1 (en) | 2017-02-08 | 2018-08-16 | Friedrich Miescher Institute For Biomedical Research | Synp88, a promoter for the specific expression of genes in retinal ganglion cells |
| MX2020005033A (es) | 2017-11-15 | 2020-10-28 | Friedrich Miescher Institute For Biomedical Res | Promotor especifico de las celulas del epitelio pigmentario retinal en primates. |
| SG11202005024QA (en) | 2017-11-30 | 2020-06-29 | Friedrich Miescher Institute For Biomedical Res | Synpiii, a promoter for the specific expression of genes in retinal pigment epithelium |
| CN111527102A (zh) | 2017-11-30 | 2020-08-11 | 弗里德里克·米谢尔生物医学研究所 | 灵长类动物视网膜色素上皮细胞特异性启动子SynP61 |
| EP3870709A1 (en) | 2018-10-25 | 2021-09-01 | Friedrich Miescher Institute for Biomedical Research | Synp27 (prob12), a promoter for the specific expression of genes in protoplasmic astrocytes |
| JP2022505517A (ja) | 2018-10-25 | 2022-01-14 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターＳｙｎＰ１５１（ＰｒｏＣ２９） |
| EP3870240A1 (en) | 2018-10-25 | 2021-09-01 | Friedrich Miescher Institute for Biomedical Research | Synp78 (proa27), a promoter for the specific expression of genes in retinal ganglion cells |
| EP3870239A1 (en) | 2018-10-25 | 2021-09-01 | Friedrich Miescher Institute for Biomedical Research | Synp57 (proa14), a promoter for the specific expression of genes in photoreceptors |
| WO2020084537A1 (en) | 2018-10-25 | 2020-04-30 | Friedrich Miescher Institute For Biomedical Research | Synp17 (prob1), a promoter for the specific expression of genes in retinal ganglion cells |
| US20210353773A1 (en) | 2018-10-25 | 2021-11-18 | Friedrich Miescher Institute For Biomedical Research | Synp194 (prob15), a promoter for the specific expression of genes in retinal ganglion cells |
| US20220119841A1 (en) | 2019-01-24 | 2022-04-21 | Friedrich Miescher Instit for Biomedical Research | Synp5 (proa9), a promoter for the specific expression of genes in retinal ganglion cells |
| EP3914300A1 (en) | 2019-01-24 | 2021-12-01 | Friedrich Miescher Institute for Biomedical Research | Synp66 (proa21), a promoter for the specific expression of genes in retinal ganglion cells |
| US20220119807A1 (en) | 2019-01-24 | 2022-04-21 | Friedrich Miescher Institute For Biomedical Research | Synp35 (proc8), a promoter for the specific expression of genes in retinal ganglion cells |
| WO2020152626A1 (en) | 2019-01-24 | 2020-07-30 | Friedrich Miescher Institute For Biomedical Research | Synp166 (proa36), a promoter for the specific expression of genes in photoreceptors |
| SG11202108044YA (en) | 2019-02-25 | 2021-09-29 | Novartis Ag | Compositions and methods to treat bietti crystalline dystrophy |
| US20220154211A1 (en) | 2019-02-25 | 2022-05-19 | Novartis Ag | Compositions and methods to treat bietti crystalline dystrophy |
-
2018
- 2018-11-15 MX MX2020005033A patent/MX2020005033A/es unknown
- 2018-11-15 CR CR20200210A patent/CR20200210A/es unknown
- 2018-11-15 CA CA3082080A patent/CA3082080A1/en active Pending
- 2018-11-15 US US16/764,306 patent/US11739349B2/en active Active
- 2018-11-15 SG SG11202004205YA patent/SG11202004205YA/en unknown
- 2018-11-15 AU AU2018369975A patent/AU2018369975B2/en not_active Ceased
- 2018-11-15 WO PCT/IB2018/059015 patent/WO2019097454A1/en not_active Ceased
- 2018-11-15 BR BR112020009579-6A patent/BR112020009579A2/pt not_active Application Discontinuation
- 2018-11-15 CN CN201880074227.7A patent/CN111726985B/zh not_active Expired - Fee Related
- 2018-11-15 KR KR1020207016484A patent/KR20200084028A/ko not_active Ceased
- 2018-11-15 JP JP2020526394A patent/JP7348176B2/ja active Active
- 2018-11-15 EP EP18808513.8A patent/EP3709798B1/en active Active
-
2020
- 2020-05-05 IL IL274460A patent/IL274460A/en unknown
- 2020-05-13 PH PH12020550757A patent/PH12020550757A1/en unknown
-
2023
- 2023-02-22 JP JP2023025663A patent/JP2023075139A/ja active Pending
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