JP2021502104A5 - - Google Patents
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- JP2021502104A5 JP2021502104A5 JP2020526175A JP2020526175A JP2021502104A5 JP 2021502104 A5 JP2021502104 A5 JP 2021502104A5 JP 2020526175 A JP2020526175 A JP 2020526175A JP 2020526175 A JP2020526175 A JP 2020526175A JP 2021502104 A5 JP2021502104 A5 JP 2021502104A5
- Authority
- JP
- Japan
- Prior art keywords
- heavy chain
- cancer
- domain antibody
- single variable
- variable heavy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023111710A JP2023126951A (ja) | 2017-11-13 | 2023-07-06 | Ｃｄ１３７に結合するシングルドメイン抗体 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1718735.2 | 2017-11-13 | ||
| GB1718734.5 | 2017-11-13 | ||
| GBGB1718734.5A GB201718734D0 (en) | 2017-11-13 | 2017-11-13 | Single domain antibodies that bind to CD137 |
| GBGB1718735.2A GB201718735D0 (en) | 2017-11-13 | 2017-11-13 | Bispecific molecules that bind to CD137 and PSMA |
| GB1808589.4 | 2018-05-24 | ||
| GBGB1808589.4A GB201808589D0 (en) | 2018-05-24 | 2018-05-24 | Single domain antibodies that bind CD137 |
| PCT/GB2018/053279 WO2019092451A1 (en) | 2017-11-13 | 2018-11-13 | Single Domain Antibodies that Bind to CD137 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023111710A Division JP2023126951A (ja) | 2017-11-13 | 2023-07-06 | Ｃｄ１３７に結合するシングルドメイン抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021502104A JP2021502104A (ja) | 2021-01-28 |
| JP2021502104A5 true JP2021502104A5 (enExample) | 2021-12-23 |
| JP7312168B2 JP7312168B2 (ja) | 2023-07-20 |
Family
ID=64457031
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526245A Ceased JP2021502810A (ja) | 2017-11-13 | 2018-11-13 | Ｃｄ１３７およびｐｓｍａに結合する分子 |
| JP2020526175A Active JP7312168B2 (ja) | 2017-11-13 | 2018-11-13 | Ｃｄ１３７に結合するシングルドメイン抗体 |
| JP2023111710A Pending JP2023126951A (ja) | 2017-11-13 | 2023-07-06 | Ｃｄ１３７に結合するシングルドメイン抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526245A Ceased JP2021502810A (ja) | 2017-11-13 | 2018-11-13 | Ｃｄ１３７およびｐｓｍａに結合する分子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023111710A Pending JP2023126951A (ja) | 2017-11-13 | 2023-07-06 | Ｃｄ１３７に結合するシングルドメイン抗体 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20200362051A1 (enExample) |
| EP (2) | EP3710477A1 (enExample) |
| JP (3) | JP2021502810A (enExample) |
| KR (2) | KR20200080304A (enExample) |
| CN (4) | CN111699197B (enExample) |
| AU (2) | AU2018363292A1 (enExample) |
| CA (2) | CA3082297A1 (enExample) |
| IL (2) | IL274371A (enExample) |
| SG (2) | SG11202003978UA (enExample) |
| WO (2) | WO2019092452A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019506155A (ja) | 2016-01-12 | 2019-03-07 | クレッシェンド、バイオロジックス、リミテッドＣｒｅｓｃｅｎｄｏ Ｂｉｏｌｏｇｉｃｓ Ｌｉｍｉｔｅｄ | 治療分子 |
| GB201607968D0 (en) | 2016-05-06 | 2016-06-22 | Crescendo Biolog Ltd | Chimeric antigen receptor |
| EP3565842A1 (en) | 2017-01-06 | 2019-11-13 | Crescendo Biologics Limited | Single domain antibodies to programmed cell death (pd-1) |
| GB201711068D0 (en) * | 2017-07-10 | 2017-08-23 | Crescendo Biologics Ltd | Therapeutic molecules binding PSMA |
| CA3082297A1 (en) * | 2017-11-13 | 2019-05-16 | Crescendo Biologics Limited | Molecules that bind to cd137 and psma |
| GB201802573D0 (en) | 2018-02-16 | 2018-04-04 | Crescendo Biologics Ltd | Therapeutic molecules that bind to LAG3 |
| JP2020132572A (ja) * | 2019-02-20 | 2020-08-31 | 旭化成株式会社 | シラノール組成物、硬化物及び製造方法 |
| US20220220215A1 (en) * | 2019-05-15 | 2022-07-14 | Crescendo Biologics Limited | Binding molecules |
| US11261259B2 (en) * | 2019-08-12 | 2022-03-01 | I-Mab Biopharma Us Limited | Anti-claudin 18.2 and anti-4-1BB bispecific antibodies and uses thereof |
| KR20220087479A (ko) * | 2019-11-13 | 2022-06-24 | 허페이 한커맵 바이오테크놀로지 컴퍼니 리미티드 | 인간 4-1bb와 결합할 수 있는 분자 및 이의 응용 |
| MX2022005983A (es) | 2019-11-18 | 2022-09-07 | Janssen Biotech Inc | Receptores del antígeno quimérico anti-cd79, células car-t, y usos de estos. |
| WO2022002063A1 (zh) * | 2020-06-30 | 2022-01-06 | 和铂医药(上海)有限责任公司 | 一种4-1bb结合蛋白及其应用 |
| AU2021345124A1 (en) | 2020-09-16 | 2023-03-30 | Amgen Inc. | Methods for administering therapeutic doses of bispecific T-cell engaging molecules for the treatment of cancer |
| CN114195894B (zh) * | 2020-09-17 | 2025-02-25 | 普米斯生物技术(珠海)有限公司 | 一种靶向4-1bb的抗体及其应用 |
| CN117355540A (zh) * | 2021-05-21 | 2024-01-05 | 百济神州有限公司 | 抗cd137抗体和使用方法 |
| WO2022242682A1 (en) * | 2021-05-21 | 2022-11-24 | Beigene, Ltd. | Anti-gpc3 and anti-cd137 multispecific antibodies and methods of use |
| CN113621065B (zh) * | 2021-08-30 | 2023-08-01 | 武汉海沙百得生物技术有限公司 | 靶向4-1bb的全人源抗体及其制备方法和应用 |
| JP2024530325A (ja) * | 2021-08-31 | 2024-08-16 | ラノバ メディシンズ リミテッド | 抗４－１ｂｂナノボディ |
| WO2024040195A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
| JP2025529310A (ja) * | 2022-09-06 | 2025-09-04 | ティージェイ バイオファーマ （シャンハイ） カンパニー， リミテッド | 多特異性構築物およびその使用 |
| EP4789724A2 (en) * | 2022-09-22 | 2026-08-12 | ABlink Biotech Co., Ltd. | Anti-4-1bb nanobody 137-7, preparation therefor, and use thereof |
| CN122255279A (zh) * | 2022-11-21 | 2026-06-23 | 广州百济神州生物制药有限公司 | 抗cd137抗体和使用方法 |
| KR20240164748A (ko) * | 2023-05-12 | 2024-11-20 | 앱클론(주) | 항체 또는 그의 항원 결합 단편, 및 어피바디를 포함하는 이중 항원 표적 단백질 복합체 |
| EP4719352A1 (en) | 2023-05-31 | 2026-04-08 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| JP2025022410A (ja) | 2023-08-03 | 2025-02-14 | ルネサスエレクトロニクス株式会社 | 半導体装置およびその製造方法 |
| US20250127728A1 (en) | 2023-10-05 | 2025-04-24 | Capstan Therapeutics, Inc. | Constrained Ionizable Cationic Lipids and Lipid Nanoparticles |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| US20250302763A1 (en) | 2024-02-22 | 2025-10-02 | Capstan Therapeutics, Inc. | Immune engineering amplification |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025214249A1 (en) * | 2024-04-12 | 2025-10-16 | Suzhou Biomissile Pharmaceuticals Co., Ltd. | Anti-4-bb single domain antibodies, bispecific antibodies and uses thereof |
| CN118629502A (zh) * | 2024-06-19 | 2024-09-10 | 中山百灵生物技术股份有限公司 | 基于数据处理的核苷酸序列实验预测优化系统 |
| WO2026096576A1 (en) * | 2024-10-30 | 2026-05-07 | Regeneron Pharmaceuticals, Inc. | Multispecific antigen-binding molecules that bind psma and 4-1bb and methods of use thereof |
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| JP2019506155A (ja) * | 2016-01-12 | 2019-03-07 | クレッシェンド、バイオロジックス、リミテッドＣｒｅｓｃｅｎｄｏ Ｂｉｏｌｏｇｉｃｓ Ｌｉｍｉｔｅｄ | 治療分子 |
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| EP3565842A1 (en) | 2017-01-06 | 2019-11-13 | Crescendo Biologics Limited | Single domain antibodies to programmed cell death (pd-1) |
| WO2018148223A1 (en) | 2017-02-09 | 2018-08-16 | Memorial Sloan Kettering Cancer Center | Anti-kir3dl1 antibodies |
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| GB201711068D0 (en) | 2017-07-10 | 2017-08-23 | Crescendo Biologics Ltd | Therapeutic molecules binding PSMA |
| US12202911B2 (en) * | 2017-10-10 | 2025-01-21 | Numab Therapeutics AG | Multispecific antibody comprising CD137 binding domain and PDL1 binding domain |
| EP3470426A1 (en) | 2017-10-10 | 2019-04-17 | Numab Therapeutics AG | Multispecific antibody |
| CA3082297A1 (en) | 2017-11-13 | 2019-05-16 | Crescendo Biologics Limited | Molecules that bind to cd137 and psma |
| GB201802573D0 (en) | 2018-02-16 | 2018-04-04 | Crescendo Biologics Ltd | Therapeutic molecules that bind to LAG3 |
| GB201818460D0 (en) | 2018-11-13 | 2018-12-26 | Crescendo Biologics Ltd | Single domain antibodies that bind human serum albumin |
| US20220220215A1 (en) | 2019-05-15 | 2022-07-14 | Crescendo Biologics Limited | Binding molecules |
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2018
- 2018-11-13 CA CA3082297A patent/CA3082297A1/en active Pending
- 2018-11-13 JP JP2020526245A patent/JP2021502810A/ja not_active Ceased
- 2018-11-13 SG SG11202003978UA patent/SG11202003978UA/en unknown
- 2018-11-13 JP JP2020526175A patent/JP7312168B2/ja active Active
- 2018-11-13 CN CN201880085847.0A patent/CN111699197B/zh active Active
- 2018-11-13 WO PCT/GB2018/053280 patent/WO2019092452A1/en not_active Ceased
- 2018-11-13 US US16/763,063 patent/US20200362051A1/en not_active Abandoned
- 2018-11-13 CN CN202411099964.6A patent/CN118955716A/zh active Pending
- 2018-11-13 EP EP18808057.6A patent/EP3710477A1/en active Pending
- 2018-11-13 KR KR1020207016093A patent/KR20200080304A/ko not_active Ceased
- 2018-11-13 WO PCT/GB2018/053279 patent/WO2019092451A1/en not_active Ceased
- 2018-11-13 AU AU2018363292A patent/AU2018363292A1/en not_active Abandoned
- 2018-11-13 CN CN201880086045.1A patent/CN111683968B/zh active Active
- 2018-11-13 EP EP18808058.4A patent/EP3710478A1/en active Pending
- 2018-11-13 CA CA3082321A patent/CA3082321A1/en active Pending
- 2018-11-13 CN CN202410837001.5A patent/CN118667027A/zh active Pending
- 2018-11-13 SG SG11202003912RA patent/SG11202003912RA/en unknown
- 2018-11-13 US US16/763,059 patent/US12077595B2/en active Active
- 2018-11-13 KR KR1020207016092A patent/KR20200083574A/ko not_active Ceased
- 2018-11-13 AU AU2018363291A patent/AU2018363291A1/en not_active Abandoned
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2020
- 2020-04-30 IL IL274371A patent/IL274371A/en unknown
- 2020-04-30 IL IL274370A patent/IL274370A/en unknown
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2023
- 2023-07-06 JP JP2023111710A patent/JP2023126951A/ja active Pending