JP2021502069A5 - - Google Patents
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- JP2021502069A5 JP2021502069A5 JP2020524429A JP2020524429A JP2021502069A5 JP 2021502069 A5 JP2021502069 A5 JP 2021502069A5 JP 2020524429 A JP2020524429 A JP 2020524429A JP 2020524429 A JP2020524429 A JP 2020524429A JP 2021502069 A5 JP2021502069 A5 JP 2021502069A5
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- 239000000523 sample Substances 0.000 claims description 121
- 102000042567 non-coding RNA Human genes 0.000 claims description 93
- 108091027963 non-coding RNA Proteins 0.000 claims description 93
- 238000000034 method Methods 0.000 claims description 77
- 239000012634 fragment Substances 0.000 claims description 39
- 150000007523 nucleic acids Chemical class 0.000 claims description 24
- 230000000295 complement effect Effects 0.000 claims description 16
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims description 15
- 201000011510 cancer Diseases 0.000 claims description 14
- 206010028980 Neoplasm Diseases 0.000 claims description 13
- 206010006187 Breast cancer Diseases 0.000 claims description 11
- 208000026310 Breast neoplasm Diseases 0.000 claims description 11
- 239000013068 control sample Substances 0.000 claims description 11
- 102000039446 nucleic acids Human genes 0.000 claims description 11
- 108020004707 nucleic acids Proteins 0.000 claims description 11
- 230000003463 hyperproliferative effect Effects 0.000 claims description 10
- 210000002966 serum Anatomy 0.000 claims description 9
- 230000003211 malignant effect Effects 0.000 claims description 7
- 238000001574 biopsy Methods 0.000 claims description 5
- 210000002381 plasma Anatomy 0.000 claims description 5
- 238000010241 blood sampling Methods 0.000 claims description 4
- 230000001680 brushing effect Effects 0.000 claims description 4
- 210000004369 blood Anatomy 0.000 claims description 3
- 239000008280 blood Substances 0.000 claims description 3
- 238000012300 Sequence Analysis Methods 0.000 claims description 2
- 238000004458 analytical method Methods 0.000 claims description 2
- 238000004587 chromatography analysis Methods 0.000 claims description 2
- 239000000975 dye Substances 0.000 claims description 2
- 238000000799 fluorescence microscopy Methods 0.000 claims description 2
- 239000007850 fluorescent dye Substances 0.000 claims description 2
- 238000002955 isolation Methods 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 238000005259 measurement Methods 0.000 claims description 2
- 210000000115 thoracic cavity Anatomy 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 4
- 210000004027 cell Anatomy 0.000 description 14
- 210000001519 tissue Anatomy 0.000 description 8
- 238000001514 detection method Methods 0.000 description 6
- 239000000758 substrate Substances 0.000 description 4
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000011002 quantification Methods 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 1
- 239000005081 chemiluminescent agent Substances 0.000 description 1
- 238000010205 computational analysis Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000012632 fluorescent imaging Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000013558 reference substance Substances 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023171655A JP2024009855A (ja) | 2017-11-12 | 2023-10-02 | がんを検出するための非コードｒｎａ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762584899P | 2017-11-12 | 2017-11-12 | |
| US62/584,899 | 2017-11-12 | ||
| PCT/US2018/060113 WO2019094780A2 (en) | 2017-11-12 | 2018-11-09 | Non-coding rna for detection of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023171655A Division JP2024009855A (ja) | 2017-11-12 | 2023-10-02 | がんを検出するための非コードｒｎａ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021502069A JP2021502069A (ja) | 2021-01-28 |
| JP2021502069A5 true JP2021502069A5 (enExample) | 2021-12-23 |
| JP7549880B2 JP7549880B2 (ja) | 2024-09-12 |
Family
ID=66439063
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020524429A Active JP7549880B2 (ja) | 2017-11-12 | 2018-11-09 | がんを検出するための非コードｒｎａ |
| JP2023171655A Pending JP2024009855A (ja) | 2017-11-12 | 2023-10-02 | がんを検出するための非コードｒｎａ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023171655A Pending JP2024009855A (ja) | 2017-11-12 | 2023-10-02 | がんを検出するための非コードｒｎａ |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20200362420A1 (enExample) |
| EP (1) | EP3707259A4 (enExample) |
| JP (2) | JP7549880B2 (enExample) |
| CN (1) | CN111344409A (enExample) |
| AU (2) | AU2018364987A1 (enExample) |
| CA (1) | CA3082391A1 (enExample) |
| MX (1) | MX2020004949A (enExample) |
| WO (1) | WO2019094780A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3571315B1 (en) | 2017-01-23 | 2025-01-08 | Gatehouse Bio, Inc. | Methods for identifying and using small rna predictors |
| WO2021102228A1 (en) * | 2019-11-21 | 2021-05-27 | Icahn School Of Medicine At Mount Sinai | Small unannotated, non-coding rnas for the detection of liver cancer |
| CA3168874A1 (en) * | 2020-01-22 | 2021-07-29 | Gatehouse Bio, Inc. | Small rna disease classifiers |
| WO2022029488A1 (en) * | 2020-08-06 | 2022-02-10 | Agenda Nv | Systems and methods of assessing breast cancer |
| JP2023538900A (ja) * | 2020-08-16 | 2023-09-12 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | がん診断のためのｏｎｃＲＮＡの検出のシステム及び方法 |
| WO2022101672A2 (en) | 2020-11-11 | 2022-05-19 | Agendia NV | Method of assessing diseases using image classifiers |
| EP4500535A2 (en) * | 2022-03-29 | 2025-02-05 | The Regents Of The University Of California | Methods for determining the presence, type, grade, classification of a tumor, cyst, lesion, mass, and/or cancer |
| WO2025033530A1 (ja) * | 2023-08-10 | 2025-02-13 | 国立大学法人山口大学 | 大腸癌の診断マーカー |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070065844A1 (en) * | 2005-06-08 | 2007-03-22 | Massachusetts Institute Of Technology | Solution-based methods for RNA expression profiling |
| US20080076674A1 (en) * | 2006-07-06 | 2008-03-27 | Thomas Litman | Novel oligonucleotide compositions and probe sequences useful for detection and analysis of non coding RNAs associated with cancer |
| WO2008109556A1 (en) * | 2007-03-02 | 2008-09-12 | Mdrna, Inc. | Nucleic acid compounds for inhibiting telomerase gene expression and uses thereof |
| CN104031984A (zh) * | 2008-02-28 | 2014-09-10 | 俄亥俄州立大学研究基金会 | 用于前列腺相关病症的诊断、预后和治疗的基于微rna的方法和组合物 |
| US20110136124A1 (en) * | 2009-09-23 | 2011-06-09 | Wilson Roa | Microrna expression profiles associated with lung cancer |
| EP2388336A1 (en) * | 2010-05-19 | 2011-11-23 | Signature Diagnostics AG | Method and kits for diagnosing colorectal cancer |
| US20150284802A1 (en) * | 2010-11-19 | 2015-10-08 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| US9771617B2 (en) * | 2011-06-27 | 2017-09-26 | Eisai R&D Management Co., Ltd. | Microrna biomarkers indicative of alzheimer's disease |
| EP3492606B1 (en) * | 2011-08-22 | 2023-10-04 | Exosome Diagnostics, Inc. | Urine biomarkers |
| JP2014003925A (ja) * | 2012-06-22 | 2014-01-16 | Japanese Foundation For Cancer Research | 予後不良の肺小細胞がんの検査方法及び治療手段 |
| WO2017190003A1 (en) * | 2016-04-28 | 2017-11-02 | Joslin Diabetes Center, Inc. | Compositions and method for treating and preventing end stage renal disease |
-
2018
- 2018-11-09 CA CA3082391A patent/CA3082391A1/en active Pending
- 2018-11-09 EP EP18876580.4A patent/EP3707259A4/en active Pending
- 2018-11-09 US US16/763,540 patent/US20200362420A1/en not_active Abandoned
- 2018-11-09 JP JP2020524429A patent/JP7549880B2/ja active Active
- 2018-11-09 MX MX2020004949A patent/MX2020004949A/es unknown
- 2018-11-09 AU AU2018364987A patent/AU2018364987A1/en not_active Abandoned
- 2018-11-09 CN CN201880073234.5A patent/CN111344409A/zh active Pending
- 2018-11-09 WO PCT/US2018/060113 patent/WO2019094780A2/en not_active Ceased
-
2022
- 2022-04-15 US US17/722,051 patent/US20220325359A1/en not_active Abandoned
-
2023
- 2023-10-02 JP JP2023171655A patent/JP2024009855A/ja active Pending
-
2024
- 2024-01-31 US US18/429,051 patent/US12398429B2/en active Active
- 2024-06-24 US US18/752,640 patent/US20250154598A1/en active Pending
-
2025
- 2025-06-27 AU AU2025204881A patent/AU2025204881B2/en active Active
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