JP7549880B2 - がんを検出するための非コードｒｎａ - Google Patents

がんを検出するための非コードｒｎａ Download PDF

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JP7549880B2
JP7549880B2 JP2020524429A JP2020524429A JP7549880B2 JP 7549880 B2 JP7549880 B2 JP 7549880B2 JP 2020524429 A JP2020524429 A JP 2020524429A JP 2020524429 A JP2020524429 A JP 2020524429A JP 7549880 B2 JP7549880 B2 JP 7549880B2
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seq
sample
coding rna
rna
coding
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JP2021502069A (ja
JP2021502069A5 (enExample
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ハニ グッダルジ，
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University of California San Diego UCSD
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University of California San Diego UCSD
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2020524429A 2017-11-12 2018-11-09 がんを検出するための非コードｒｎａ Active JP7549880B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023171655A JP2024009855A (ja) 2017-11-12 2023-10-02 がんを検出するための非コードｒｎａ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762584899P 2017-11-12 2017-11-12
US62/584,899 2017-11-12
PCT/US2018/060113 WO2019094780A2 (en) 2017-11-12 2018-11-09 Non-coding rna for detection of cancer

Related Child Applications (1)

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JP2023171655A Division JP2024009855A (ja) 2017-11-12 2023-10-02 がんを検出するための非コードｒｎａ

Publications (3)

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JP2021502069A JP2021502069A (ja) 2021-01-28
JP2021502069A5 JP2021502069A5 (enExample) 2021-12-23
JP7549880B2 true JP7549880B2 (ja) 2024-09-12

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JP2020524429A Active JP7549880B2 (ja) 2017-11-12 2018-11-09 がんを検出するための非コードｒｎａ
JP2023171655A Pending JP2024009855A (ja) 2017-11-12 2023-10-02 がんを検出するための非コードｒｎａ

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US (4) US20200362420A1 (enExample)
EP (1) EP3707259A4 (enExample)
JP (2) JP7549880B2 (enExample)
CN (1) CN111344409A (enExample)
AU (2) AU2018364987A1 (enExample)
CA (1) CA3082391A1 (enExample)
MX (1) MX2020004949A (enExample)
WO (1) WO2019094780A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110418850B (zh) 2017-01-23 2024-04-16 盖特豪斯生物股份有限公司 鉴定和使用小rna预测因子的方法
US20230027285A1 (en) * 2019-11-21 2023-01-26 Icahn School Of Medicine At Mount Sinai Small unannotated, non-coding rnas for the detection of liver cancer
EP4093744A4 (en) * 2020-01-22 2024-01-17 Gatehouse Bio, Inc. SMALL RNA-BASED DISEASE CLASSIFIERS
WO2022029488A1 (en) * 2020-08-06 2022-02-10 Agenda Nv Systems and methods of assessing breast cancer
AU2021329814A1 (en) * 2020-08-16 2023-03-23 The Regents Of The University Of California System and methods of detection of oncrnas for cancer diagnosis
WO2022101672A2 (en) 2020-11-11 2022-05-19 Agendia NV Method of assessing diseases using image classifiers
WO2023192227A2 (en) * 2022-03-29 2023-10-05 The Regents Of The University Of California Methods for determining the presence, type, grade, classification of a tumor, cyst, lesion, mass, and/or cancer
WO2025033530A1 (ja) * 2023-08-10 2025-02-13 国立大学法人山口大学 大腸癌の診断マーカー

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014003925A (ja) 2012-06-22 2014-01-16 Japanese Foundation For Cancer Research 予後不良の肺小細胞がんの検査方法及び治療手段

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US20070065844A1 (en) * 2005-06-08 2007-03-22 Massachusetts Institute Of Technology Solution-based methods for RNA expression profiling
US20080076674A1 (en) * 2006-07-06 2008-03-27 Thomas Litman Novel oligonucleotide compositions and probe sequences useful for detection and analysis of non coding RNAs associated with cancer
WO2008109556A1 (en) * 2007-03-02 2008-09-12 Mdrna, Inc. Nucleic acid compounds for inhibiting telomerase gene expression and uses thereof
EP3112477A1 (en) * 2008-02-28 2017-01-04 The Ohio State University Research Foundation Microrna-based methods and compositions for the diagnosis, prognosis and treatment of prostate related disorders
US20110136124A1 (en) * 2009-09-23 2011-06-09 Wilson Roa Microrna expression profiles associated with lung cancer
EP2388336A1 (en) * 2010-05-19 2011-11-23 Signature Diagnostics AG Method and kits for diagnosing colorectal cancer
WO2012068383A2 (en) * 2010-11-19 2012-05-24 The Regents Of The University Of Michigan ncRNA AND USES THEREOF
AU2012275556B2 (en) * 2011-06-27 2016-02-04 Eisai R&D Management Co., Ltd. MicroRNA biomarkers indicative of Alzheimer's Disease
EP2748335B1 (en) * 2011-08-22 2018-10-03 Exosome Diagnostics, Inc. Urine biomarkers
WO2017190003A1 (en) * 2016-04-28 2017-11-02 Joslin Diabetes Center, Inc. Compositions and method for treating and preventing end stage renal disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014003925A (ja) 2012-06-22 2014-01-16 Japanese Foundation For Cancer Research 予後不良の肺小細胞がんの検査方法及び治療手段

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
RASOOL, M., et al.，"Non-coding RNAs in cancer diagnosis and therapy."，NON-CODING RNA RESEARCH，2016年11月11日，Vol.1, No.1，pp.69-76，DOI: 10.1016/j.ncrna.2016.11.001

Also Published As

Publication number Publication date
EP3707259A4 (en) 2021-08-11
US12398429B2 (en) 2025-08-26
MX2020004949A (es) 2020-08-27
US20220325359A1 (en) 2022-10-13
JP2021502069A (ja) 2021-01-28
AU2018364987A1 (en) 2020-04-23
WO2019094780A3 (en) 2020-04-02
AU2025204881A1 (en) 2025-07-17
JP2024009855A (ja) 2024-01-23
EP3707259A2 (en) 2020-09-16
CN111344409A (zh) 2020-06-26
AU2025204881B2 (en) 2025-10-02
US20250154598A1 (en) 2025-05-15
CA3082391A1 (en) 2019-05-16
US20200362420A1 (en) 2020-11-19
US20250101509A1 (en) 2025-03-27
WO2019094780A2 (en) 2019-05-16

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