CN111344409A - 用于检测癌症的非编码rna - Google Patents

用于检测癌症的非编码rna Download PDF

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Publication number
CN111344409A
CN111344409A CN201880073234.5A CN201880073234A CN111344409A CN 111344409 A CN111344409 A CN 111344409A CN 201880073234 A CN201880073234 A CN 201880073234A CN 111344409 A CN111344409 A CN 111344409A
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sample
coding rna
amount
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rna
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CN201880073234.5A
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Chinese (zh)
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H·古达兹
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University of California San Diego UCSD
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University of California San Diego UCSD
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201880073234.5A 2017-11-12 2018-11-09 用于检测癌症的非编码rna Pending CN111344409A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762584899P 2017-11-12 2017-11-12
US62/584,899 2017-11-12
PCT/US2018/060113 WO2019094780A2 (en) 2017-11-12 2018-11-09 Non-coding rna for detection of cancer

Publications (1)

Publication Number Publication Date
CN111344409A true CN111344409A (zh) 2020-06-26

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CN201880073234.5A Pending CN111344409A (zh) 2017-11-12 2018-11-09 用于检测癌症的非编码rna

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US (4) US20200362420A1 (enExample)
EP (1) EP3707259A4 (enExample)
JP (2) JP7549880B2 (enExample)
CN (1) CN111344409A (enExample)
AU (2) AU2018364987A1 (enExample)
CA (1) CA3082391A1 (enExample)
MX (1) MX2020004949A (enExample)
WO (1) WO2019094780A2 (enExample)

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Publication number Priority date Publication date Assignee Title
US10889862B2 (en) 2017-01-23 2021-01-12 Srnalytics, Llc. Methods for identifying and using small RNA predictors
WO2021102228A1 (en) * 2019-11-21 2021-05-27 Icahn School Of Medicine At Mount Sinai Small unannotated, non-coding rnas for the detection of liver cancer
EP4093744A4 (en) * 2020-01-22 2024-01-17 Gatehouse Bio, Inc. SMALL RNA-BASED DISEASE CLASSIFIERS
US20220042108A1 (en) * 2020-08-06 2022-02-10 Agendia NV Systems and methods of assessing breast cancer
CA3192008A1 (en) * 2020-08-16 2022-02-24 The Regents Of The University Of California System and methods of detection of oncrnas for cancer diagnosis
WO2022101672A2 (en) 2020-11-11 2022-05-19 Agendia NV Method of assessing diseases using image classifiers
US20250218588A1 (en) * 2022-03-29 2025-07-03 The Regents Of The University Of California Methods for determining the presence, type, or grade of a tumor, cyst, or mass, or subtyping a cancer
WO2025033530A1 (ja) * 2023-08-10 2025-02-13 国立大学法人山口大学 大腸癌の診断マーカー

Citations (3)

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US20080076674A1 (en) * 2006-07-06 2008-03-27 Thomas Litman Novel oligonucleotide compositions and probe sequences useful for detection and analysis of non coding RNAs associated with cancer
CN103403181A (zh) * 2010-11-19 2013-11-20 密执安大学评议会 ncRNA及其用途
CN104031984A (zh) * 2008-02-28 2014-09-10 俄亥俄州立大学研究基金会 用于前列腺相关病症的诊断、预后和治疗的基于微rna的方法和组合物

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US20070065844A1 (en) * 2005-06-08 2007-03-22 Massachusetts Institute Of Technology Solution-based methods for RNA expression profiling
WO2008109556A1 (en) * 2007-03-02 2008-09-12 Mdrna, Inc. Nucleic acid compounds for inhibiting telomerase gene expression and uses thereof
US20110136124A1 (en) * 2009-09-23 2011-06-09 Wilson Roa Microrna expression profiles associated with lung cancer
EP2388336A1 (en) * 2010-05-19 2011-11-23 Signature Diagnostics AG Method and kits for diagnosing colorectal cancer
EP2723894B1 (en) * 2011-06-27 2016-05-11 Eisai R&D Management Co., Ltd. Microrna biomarkers indicative of alzheimer's disease
EP2748335B1 (en) * 2011-08-22 2018-10-03 Exosome Diagnostics, Inc. Urine biomarkers
JP2014003925A (ja) * 2012-06-22 2014-01-16 Japanese Foundation For Cancer Research 予後不良の肺小細胞がんの検査方法及び治療手段
WO2017190003A1 (en) * 2016-04-28 2017-11-02 Joslin Diabetes Center, Inc. Compositions and method for treating and preventing end stage renal disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080076674A1 (en) * 2006-07-06 2008-03-27 Thomas Litman Novel oligonucleotide compositions and probe sequences useful for detection and analysis of non coding RNAs associated with cancer
CN104031984A (zh) * 2008-02-28 2014-09-10 俄亥俄州立大学研究基金会 用于前列腺相关病症的诊断、预后和治疗的基于微rna的方法和组合物
CN103403181A (zh) * 2010-11-19 2013-11-20 密执安大学评议会 ncRNA及其用途

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
孙效文等: "水产基因组技术与研究进展", 31 July 2011, 海洋出版社, pages: 105 - 106 *
李伟等: "分子诊断学", 30 September 2015, 中国医药科技出版社, pages: 104 - 107 *

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AU2025204881B2 (en) 2025-10-02
JP2021502069A (ja) 2021-01-28
US20200362420A1 (en) 2020-11-19
US20250154598A1 (en) 2025-05-15
US20250101509A1 (en) 2025-03-27
AU2018364987A1 (en) 2020-04-23
JP2024009855A (ja) 2024-01-23
JP7549880B2 (ja) 2024-09-12
AU2025204881A1 (en) 2025-07-17
WO2019094780A2 (en) 2019-05-16
MX2020004949A (es) 2020-08-27
US12398429B2 (en) 2025-08-26
EP3707259A4 (en) 2021-08-11
CA3082391A1 (en) 2019-05-16
EP3707259A2 (en) 2020-09-16
WO2019094780A3 (en) 2020-04-02
US20220325359A1 (en) 2022-10-13

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