AU2018364987A1 - Non-coding RNA for detection of cancer - Google Patents

Non-coding RNA for detection of cancer Download PDF

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Publication number
AU2018364987A1
AU2018364987A1 AU2018364987A AU2018364987A AU2018364987A1 AU 2018364987 A1 AU2018364987 A1 AU 2018364987A1 AU 2018364987 A AU2018364987 A AU 2018364987A AU 2018364987 A AU2018364987 A AU 2018364987A AU 2018364987 A1 AU2018364987 A1 AU 2018364987A1
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AU
Australia
Prior art keywords
sample
coding rna
rna
subject
homologous sequence
Prior art date
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Abandoned
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AU2018364987A
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English (en)
Inventor
Hani Goodarzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
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University of California Berkeley
University of California San Diego UCSD
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Publication date
Application filed by University of California Berkeley, University of California San Diego UCSD filed Critical University of California Berkeley
Publication of AU2018364987A1 publication Critical patent/AU2018364987A1/en
Priority to AU2025204881A priority Critical patent/AU2025204881B2/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2018364987A 2017-11-12 2018-11-09 Non-coding RNA for detection of cancer Abandoned AU2018364987A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2025204881A AU2025204881B2 (en) 2017-11-12 2025-06-27 Non-coding RNA for detection of cancer

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762584899P 2017-11-12 2017-11-12
US62/584,899 2017-11-12
PCT/US2018/060113 WO2019094780A2 (en) 2017-11-12 2018-11-09 Non-coding rna for detection of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2025204881A Division AU2025204881B2 (en) 2017-11-12 2025-06-27 Non-coding RNA for detection of cancer

Publications (1)

Publication Number Publication Date
AU2018364987A1 true AU2018364987A1 (en) 2020-04-23

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
AU2018364987A Abandoned AU2018364987A1 (en) 2017-11-12 2018-11-09 Non-coding RNA for detection of cancer
AU2025204881A Active AU2025204881B2 (en) 2017-11-12 2025-06-27 Non-coding RNA for detection of cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2025204881A Active AU2025204881B2 (en) 2017-11-12 2025-06-27 Non-coding RNA for detection of cancer

Country Status (8)

Country Link
US (4) US20200362420A1 (enExample)
EP (1) EP3707259A4 (enExample)
JP (2) JP7549880B2 (enExample)
CN (1) CN111344409A (enExample)
AU (2) AU2018364987A1 (enExample)
CA (1) CA3082391A1 (enExample)
MX (1) MX2020004949A (enExample)
WO (1) WO2019094780A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10889862B2 (en) 2017-01-23 2021-01-12 Srnalytics, Llc. Methods for identifying and using small RNA predictors
WO2021102228A1 (en) * 2019-11-21 2021-05-27 Icahn School Of Medicine At Mount Sinai Small unannotated, non-coding rnas for the detection of liver cancer
EP4093744A4 (en) * 2020-01-22 2024-01-17 Gatehouse Bio, Inc. SMALL RNA-BASED DISEASE CLASSIFIERS
US20220042108A1 (en) * 2020-08-06 2022-02-10 Agendia NV Systems and methods of assessing breast cancer
CA3192008A1 (en) * 2020-08-16 2022-02-24 The Regents Of The University Of California System and methods of detection of oncrnas for cancer diagnosis
WO2022101672A2 (en) 2020-11-11 2022-05-19 Agendia NV Method of assessing diseases using image classifiers
US20250218588A1 (en) * 2022-03-29 2025-07-03 The Regents Of The University Of California Methods for determining the presence, type, or grade of a tumor, cyst, or mass, or subtyping a cancer
WO2025033530A1 (ja) * 2023-08-10 2025-02-13 国立大学法人山口大学 大腸癌の診断マーカー

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070065844A1 (en) * 2005-06-08 2007-03-22 Massachusetts Institute Of Technology Solution-based methods for RNA expression profiling
US20080076674A1 (en) * 2006-07-06 2008-03-27 Thomas Litman Novel oligonucleotide compositions and probe sequences useful for detection and analysis of non coding RNAs associated with cancer
WO2008109556A1 (en) * 2007-03-02 2008-09-12 Mdrna, Inc. Nucleic acid compounds for inhibiting telomerase gene expression and uses thereof
ES2600165T3 (es) * 2008-02-28 2017-02-07 The Ohio State University Research Foundation Antagonistas de miR-32 para aumentar la respuesta del cáncer de próstata a la apoptosis
US20110136124A1 (en) * 2009-09-23 2011-06-09 Wilson Roa Microrna expression profiles associated with lung cancer
EP2388336A1 (en) * 2010-05-19 2011-11-23 Signature Diagnostics AG Method and kits for diagnosing colorectal cancer
CA3012765A1 (en) * 2010-11-19 2012-05-24 The Regents Of The University Of Michigan Ncrna and uses thereof
EP2723894B1 (en) * 2011-06-27 2016-05-11 Eisai R&D Management Co., Ltd. Microrna biomarkers indicative of alzheimer's disease
EP2748335B1 (en) * 2011-08-22 2018-10-03 Exosome Diagnostics, Inc. Urine biomarkers
JP2014003925A (ja) * 2012-06-22 2014-01-16 Japanese Foundation For Cancer Research 予後不良の肺小細胞がんの検査方法及び治療手段
WO2017190003A1 (en) * 2016-04-28 2017-11-02 Joslin Diabetes Center, Inc. Compositions and method for treating and preventing end stage renal disease

Also Published As

Publication number Publication date
AU2025204881B2 (en) 2025-10-02
CN111344409A (zh) 2020-06-26
JP2021502069A (ja) 2021-01-28
US20200362420A1 (en) 2020-11-19
US20250154598A1 (en) 2025-05-15
US20250101509A1 (en) 2025-03-27
JP2024009855A (ja) 2024-01-23
JP7549880B2 (ja) 2024-09-12
AU2025204881A1 (en) 2025-07-17
WO2019094780A2 (en) 2019-05-16
MX2020004949A (es) 2020-08-27
US12398429B2 (en) 2025-08-26
EP3707259A4 (en) 2021-08-11
CA3082391A1 (en) 2019-05-16
EP3707259A2 (en) 2020-09-16
WO2019094780A3 (en) 2020-04-02
US20220325359A1 (en) 2022-10-13

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