JP2021501596A5 - - Google Patents
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- JP2021501596A5 JP2021501596A5 JP2020524540A JP2020524540A JP2021501596A5 JP 2021501596 A5 JP2021501596 A5 JP 2021501596A5 JP 2020524540 A JP2020524540 A JP 2020524540A JP 2020524540 A JP2020524540 A JP 2020524540A JP 2021501596 A5 JP2021501596 A5 JP 2021501596A5
- Authority
- JP
- Japan
- Prior art keywords
- expansion
- lymphocytes
- interleukin
- apc
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762582163P | 2017-11-06 | 2017-11-06 | |
| US62/582,163 | 2017-11-06 | ||
| PCT/EP2018/080343 WO2019086711A1 (en) | 2017-11-06 | 2018-11-06 | Method for expansion of lymphocytes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021501596A JP2021501596A (ja) | 2021-01-21 |
| JP2021501596A5 true JP2021501596A5 (enExample) | 2021-10-28 |
| JP7357613B2 JP7357613B2 (ja) | 2023-10-06 |
Family
ID=64332272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020524540A Active JP7357613B2 (ja) | 2017-11-06 | 2018-11-06 | リンパ球の拡大方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20200338125A1 (enExample) |
| EP (1) | EP3707245A1 (enExample) |
| JP (1) | JP7357613B2 (enExample) |
| CN (1) | CN111801415A (enExample) |
| AU (1) | AU2018361561C1 (enExample) |
| CA (1) | CA3081479A1 (enExample) |
| WO (1) | WO2019086711A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3118186A1 (en) | 2018-11-05 | 2020-05-14 | Ludwig Institute For Cancer Research Ltd | Humanized and variant tgf-.beta.1 specific antibodies and methods and uses thereof |
| AU2019374496B2 (en) | 2018-11-05 | 2026-02-05 | Centre Hospitalier Universitaire Vaudois | Humanized and variant TGF-β3 specific antibodies and methods and uses thereof |
| AU2020304022A1 (en) * | 2019-06-24 | 2022-02-17 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | A peptide-based screening method to identify neoantigens for use with tumor infiltrating lymphocytes |
| JP7337373B2 (ja) * | 2019-07-29 | 2023-09-04 | サイアス株式会社 | 抗原特異的ｔ細胞の製造方法 |
| BR112022011702A2 (pt) * | 2019-12-18 | 2022-09-06 | Cbio As | Processo melhorado para cultura de linfócitos infiltrantes tumorais para uso terapêutico |
| US12365871B2 (en) | 2020-04-28 | 2025-07-22 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| WO2021239083A1 (zh) * | 2020-05-29 | 2021-12-02 | 上海君赛生物科技有限公司 | 肿瘤浸润淋巴细胞的种子细胞培养基及其应用 |
| KR20230065251A (ko) | 2020-08-07 | 2023-05-11 | 네오진 테라퓨틱스 비.브이. | 유전적으로 조작된 t 세포를 풍부화시키기 위한 방법 |
| JP2023538364A (ja) * | 2020-08-17 | 2023-09-07 | ノースウェスタン ユニバーシティ | 膠芽細胞腫および他のがんの処置のためのｂ細胞ベースの免疫治療 |
| CN116948964A (zh) | 2020-11-19 | 2023-10-27 | 苏州沙砾生物科技有限公司 | 肿瘤浸润淋巴细胞的培养方法及其用途 |
| CN112501308B (zh) * | 2020-11-30 | 2025-10-10 | 中国水产科学研究院珠江水产研究所 | 一组鳖科动物线粒体全基因组扩增通用引物 |
| WO2022135525A1 (zh) * | 2020-12-24 | 2022-06-30 | 苏州沙砾生物科技有限公司 | 肿瘤浸润淋巴细胞的制备方法及其用途 |
| CN114686430A (zh) * | 2020-12-31 | 2022-07-01 | 上海赛比曼生物科技有限公司 | 一种制备til的方法 |
| KR20230146538A (ko) * | 2021-01-20 | 2023-10-19 | 네오진 테라퓨틱스 비.브이. | 조작된 항원 제시 세포 |
| CN115315509B (zh) * | 2021-02-08 | 2024-05-07 | 苏州沙砾生物科技有限公司 | 肿瘤浸润淋巴细胞的制备方法及其用途 |
| CN117321189A (zh) * | 2021-04-30 | 2023-12-29 | 泰根制药有限公司 | 淋巴细胞的单血管扩增 |
| US20240207319A1 (en) | 2021-05-06 | 2024-06-27 | Ludwig Institute For Cancer Research Ltd | Compositions and methods for immunotherapy |
| AU2022299605A1 (en) * | 2021-06-22 | 2024-01-04 | Achilles Therapeutics Uk Limited | A method for producing antigen-specific t cells |
| US20240360410A1 (en) * | 2021-08-03 | 2024-10-31 | Suzhou Grit Biotechnology Co., Ltd. | Modified tumor infiltrating lymphocyte and use thereof |
| US20240382591A1 (en) * | 2021-09-21 | 2024-11-21 | The University Of Chicago | Methods and composition using patient-derived autologous neoantigens for treating cancer |
| CN115433713B (zh) * | 2022-03-03 | 2023-10-27 | 中山大学孙逸仙纪念医院深汕中心医院 | 一种自体肿瘤引流淋巴结淋巴细胞的制备方法及其应用 |
| WO2024261339A1 (en) | 2023-06-23 | 2024-12-26 | Tigen Pharma Sa | Lymphocyte-stimulatory matrix (lsm) and uses thereof for expansion of lymphocyte populations |
| WO2025081198A1 (en) * | 2023-10-13 | 2025-04-17 | Northwestern University | B cell production and expansion |
| WO2025131119A1 (en) * | 2023-12-22 | 2025-06-26 | Everest Medicines (China) Co., Ltd. | Cancer vaccines and uses thereof |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5858358A (en) | 1992-04-07 | 1999-01-12 | The United States Of America As Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of T cells |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| US7175843B2 (en) | 1994-06-03 | 2007-02-13 | Genetics Institute, Llc | Methods for selectively stimulating proliferation of T cells |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| US7067318B2 (en) | 1995-06-07 | 2006-06-27 | The Regents Of The University Of Michigan | Methods for transfecting T cells |
| US6291430B1 (en) | 1997-09-12 | 2001-09-18 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
| BR0108545A (pt) | 2000-02-24 | 2004-06-29 | Xcyte Therapies Inc | Estimulação e concentração simultâneas das células |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| DE60236520D1 (de) | 2001-08-16 | 2010-07-08 | Univ Pennsylvania | Synthese und verwendung von reagenzien für die verbesserte dna-lipofektion und/oder prodrug- und arzneimitteltherapien mit langsamer freisetzung |
| US8034334B2 (en) | 2002-09-06 | 2011-10-11 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Immunotherapy with in vitro-selected antigen-specific lymphocytes after non-myeloablative lymphodepleting chemotherapy |
| US9963510B2 (en) | 2005-04-15 | 2018-05-08 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| ES2707152T3 (es) | 2005-04-15 | 2019-04-02 | Macrogenics Inc | Diacuerpos covalentes y usos de los mismos |
| EP1995316A1 (de) | 2007-05-25 | 2008-11-26 | Qiagen GmbH | Verfahren zur schonenden Zellaufreinigung, Zellgewinnung und Transfektion von Zellen |
| EP2009095A1 (en) | 2007-06-28 | 2008-12-31 | Innovalor AG | Method of generating glucose-responsive cells |
| WO2009094273A2 (en) | 2008-01-15 | 2009-07-30 | Yale University | Compositions and methods for adoptive and active immunotherapy |
| CN101824400B (zh) * | 2009-03-05 | 2012-08-08 | 中国科学院微生物研究所 | 一种放大增殖抗原特异性t细胞的方法 |
| US8383099B2 (en) * | 2009-08-28 | 2013-02-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adoptive cell therapy with young T cells |
| KR102095670B1 (ko) * | 2010-05-14 | 2020-03-31 | 더 제너럴 하스피톨 코포레이션 | 종양 특이적 신생항원을 확인하는 조성물 및 방법 |
| US10023657B2 (en) | 2010-10-01 | 2018-07-17 | Ludwig Institute For Cancer Research Ltd. | Reversible protein multimers, methods for their production and use |
| JP6081483B2 (ja) * | 2011-12-12 | 2017-02-15 | セル・メディカ・リミテッド | Ｔ細胞を増殖させるプロセス |
| US20170107490A1 (en) * | 2014-06-11 | 2017-04-20 | Polybiocept Ab | Expansion of lymphocytes with a cytokine composition for active cellular immunotherapy |
| US10987412B2 (en) * | 2014-09-17 | 2021-04-27 | The John Hopkins University | Reagents and methods for identifying, enriching, and/or expanding antigen-specific T cells |
| US10973894B2 (en) * | 2014-10-02 | 2021-04-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human | Methods of isolating T cells having antigenic specificity for a cancer-specific mutation |
| WO2016145578A1 (en) * | 2015-03-13 | 2016-09-22 | Syz Cell Therapy Co. | Methods of cancer treatment using activated t cells |
| US11723962B2 (en) * | 2016-05-04 | 2023-08-15 | Fred Hutchinson Cancer Center | Cell-based neoantigen vaccines and uses thereof |
-
2018
- 2018-11-06 WO PCT/EP2018/080343 patent/WO2019086711A1/en not_active Ceased
- 2018-11-06 US US16/761,711 patent/US20200338125A1/en active Pending
- 2018-11-06 JP JP2020524540A patent/JP7357613B2/ja active Active
- 2018-11-06 AU AU2018361561A patent/AU2018361561C1/en active Active
- 2018-11-06 CN CN201880079423.3A patent/CN111801415A/zh active Pending
- 2018-11-06 CA CA3081479A patent/CA3081479A1/en active Pending
- 2018-11-06 EP EP18804249.3A patent/EP3707245A1/en active Pending
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