JP2021500881A5 - - Google Patents
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- JP2021500881A5 JP2021500881A5 JP2020521362A JP2020521362A JP2021500881A5 JP 2021500881 A5 JP2021500881 A5 JP 2021500881A5 JP 2020521362 A JP2020521362 A JP 2020521362A JP 2020521362 A JP2020521362 A JP 2020521362A JP 2021500881 A5 JP2021500881 A5 JP 2021500881A5
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- Japan
- Prior art keywords
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- lymphoma
- antigen binding
- extracellular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102100038080 B-cell receptor CD22 Human genes 0.000 claims 5
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 claims 4
- 108010029157 Sialic Acid Binding Ig-like Lectin 2 Proteins 0.000 claims 4
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 230000004068 intracellular signaling Effects 0.000 claims 4
- 101000914514 Homo sapiens T-cell-specific surface glycoprotein CD28 Proteins 0.000 claims 3
- 102100027213 T-cell-specific surface glycoprotein CD28 Human genes 0.000 claims 3
- 125000006850 spacer group Chemical group 0.000 claims 3
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims 2
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims 2
- 101000934341 Homo sapiens T-cell surface glycoprotein CD5 Proteins 0.000 claims 2
- 102100025390 Integrin beta-2 Human genes 0.000 claims 2
- 206010025323 Lymphomas Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims 2
- 102100025244 T-cell surface glycoprotein CD5 Human genes 0.000 claims 2
- 102100022153 Tumor necrosis factor receptor superfamily member 4 Human genes 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 201000005787 hematologic cancer Diseases 0.000 claims 2
- 208000024200 hematopoietic and lymphoid system neoplasm Diseases 0.000 claims 2
- 208000032839 leukemia Diseases 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical group C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 1
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 claims 1
- 102100027207 CD27 antigen Human genes 0.000 claims 1
- 102100025221 CD70 antigen Human genes 0.000 claims 1
- 102100037904 CD9 antigen Human genes 0.000 claims 1
- 102100029360 Hematopoietic cell signal transducer Human genes 0.000 claims 1
- 102100026122 High affinity immunoglobulin gamma Fc receptor I Human genes 0.000 claims 1
- 208000017604 Hodgkin disease Diseases 0.000 claims 1
- 208000021519 Hodgkin lymphoma Diseases 0.000 claims 1
- 208000010747 Hodgkins lymphoma Diseases 0.000 claims 1
- 101000884305 Homo sapiens B-cell receptor CD22 Proteins 0.000 claims 1
- 101000914511 Homo sapiens CD27 antigen Proteins 0.000 claims 1
- 101000934356 Homo sapiens CD70 antigen Proteins 0.000 claims 1
- 101000738354 Homo sapiens CD9 antigen Proteins 0.000 claims 1
- 101000990188 Homo sapiens Hematopoietic cell signal transducer Proteins 0.000 claims 1
- 101000913074 Homo sapiens High affinity immunoglobulin gamma Fc receptor I Proteins 0.000 claims 1
- 101000935040 Homo sapiens Integrin beta-2 Proteins 0.000 claims 1
- 101000777628 Homo sapiens Leukocyte antigen CD37 Proteins 0.000 claims 1
- 101000917858 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-A Proteins 0.000 claims 1
- 101000917839 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-B Proteins 0.000 claims 1
- 101000934338 Homo sapiens Myeloid cell surface antigen CD33 Proteins 0.000 claims 1
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 1
- 101000716102 Homo sapiens T-cell surface glycoprotein CD4 Proteins 0.000 claims 1
- 101000946843 Homo sapiens T-cell surface glycoprotein CD8 alpha chain Proteins 0.000 claims 1
- 101000914484 Homo sapiens T-lymphocyte activation antigen CD80 Proteins 0.000 claims 1
- 101000809875 Homo sapiens TYRO protein tyrosine kinase-binding protein Proteins 0.000 claims 1
- 101000851370 Homo sapiens Tumor necrosis factor receptor superfamily member 9 Proteins 0.000 claims 1
- 108010064593 Intercellular Adhesion Molecule-1 Proteins 0.000 claims 1
- 102100037877 Intercellular adhesion molecule 1 Human genes 0.000 claims 1
- 102100031586 Leukocyte antigen CD37 Human genes 0.000 claims 1
- 102100029185 Low affinity immunoglobulin gamma Fc region receptor III-B Human genes 0.000 claims 1
- 108010064548 Lymphocyte Function-Associated Antigen-1 Proteins 0.000 claims 1
- 208000025205 Mantle-Cell Lymphoma Diseases 0.000 claims 1
- 208000034578 Multiple myelomas Diseases 0.000 claims 1
- 102100025243 Myeloid cell surface antigen CD33 Human genes 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 1
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 1
- 108091008874 T cell receptors Proteins 0.000 claims 1
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 1
- 102100036011 T-cell surface glycoprotein CD4 Human genes 0.000 claims 1
- 102100034922 T-cell surface glycoprotein CD8 alpha chain Human genes 0.000 claims 1
- 102100027222 T-lymphocyte activation antigen CD80 Human genes 0.000 claims 1
- 102100038717 TYRO protein tyrosine kinase-binding protein Human genes 0.000 claims 1
- 101710165473 Tumor necrosis factor receptor superfamily member 4 Proteins 0.000 claims 1
- 102100036856 Tumor necrosis factor receptor superfamily member 9 Human genes 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 230000002489 hematologic effect Effects 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000011664 signaling Effects 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023076196A JP7696393B2 (ja) | 2017-10-16 | 2023-05-02 | 抗ｃｄ２２免疫療法によってがんを処置するための組成物および方法 |
| JP2025095443A JP2025138681A (ja) | 2017-10-16 | 2025-06-09 | 抗ｃｄ２２免疫療法によってがんを処置するための組成物および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762572926P | 2017-10-16 | 2017-10-16 | |
| US62/572,926 | 2017-10-16 | ||
| PCT/US2018/056011 WO2019079249A1 (en) | 2017-10-16 | 2018-10-16 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER WITH ANTI-CD22 IMMUNOTHERAPY |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023076196A Division JP7696393B2 (ja) | 2017-10-16 | 2023-05-02 | 抗ｃｄ２２免疫療法によってがんを処置するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021500881A JP2021500881A (ja) | 2021-01-14 |
| JP2021500881A5 true JP2021500881A5 (enExample) | 2021-11-25 |
| JP7275118B2 JP7275118B2 (ja) | 2023-05-17 |
Family
ID=65896005
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020521362A Active JP7275118B2 (ja) | 2017-10-16 | 2018-10-16 | 抗ｃｄ２２免疫療法によってがんを処置するための組成物および方法 |
| JP2023076196A Active JP7696393B2 (ja) | 2017-10-16 | 2023-05-02 | 抗ｃｄ２２免疫療法によってがんを処置するための組成物および方法 |
| JP2025095443A Pending JP2025138681A (ja) | 2017-10-16 | 2025-06-09 | 抗ｃｄ２２免疫療法によってがんを処置するための組成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023076196A Active JP7696393B2 (ja) | 2017-10-16 | 2023-05-02 | 抗ｃｄ２２免疫療法によってがんを処置するための組成物および方法 |
| JP2025095443A Pending JP2025138681A (ja) | 2017-10-16 | 2025-06-09 | 抗ｃｄ２２免疫療法によってがんを処置するための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10543263B2 (enExample) |
| EP (2) | EP4279584A3 (enExample) |
| JP (3) | JP7275118B2 (enExample) |
| CN (2) | CN111629735B (enExample) |
| AU (2) | AU2018352245B2 (enExample) |
| CA (1) | CA3078962A1 (enExample) |
| ES (1) | ES2958849T3 (enExample) |
| WO (1) | WO2019079249A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7275118B2 (ja) * | 2017-10-16 | 2023-05-17 | レンティジェン・テクノロジー・インコーポレイテッド | 抗ｃｄ２２免疫療法によってがんを処置するための組成物および方法 |
| WO2021021846A1 (en) * | 2019-07-29 | 2021-02-04 | The Children's Hospital Of Philadelphia | Antibodies for the diagnosis and treatment of b-cell acute lymphoblastic leukemia |
| CN113527507A (zh) * | 2020-04-16 | 2021-10-22 | 上海赛比曼生物科技有限公司 | 靶向cd22的嵌合抗原受体及其制法和应用 |
| CN112708687B (zh) * | 2021-02-04 | 2021-11-09 | 瑞安市人民医院 | 肠道菌群在肝性脑病检测中的应用 |
| WO2024040194A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
| CN116063506A (zh) * | 2022-09-02 | 2023-05-05 | 华道(上海)生物医药有限公司 | 一种分离的抗体及其用途 |
| WO2024249954A1 (en) | 2023-05-31 | 2024-12-05 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025006799A1 (en) | 2023-06-27 | 2025-01-02 | Capstan Therapeutics, Inc. | Extracorporeal and ex vivo engineering of select cell populations from peripheral blood |
| WO2025076127A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| WO2025096878A1 (en) | 2023-11-02 | 2025-05-08 | Capstan Therapeutics, Inc. | Rna for in vivo transfection with increased expression |
| WO2025129201A1 (en) | 2023-12-15 | 2025-06-19 | Capstan Therapeutics, Inc. | Humanized anti-cd8 antibodies and uses thereof |
| US20250302763A1 (en) | 2024-02-22 | 2025-10-02 | Capstan Therapeutics, Inc. | Immune engineering amplification |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
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2018
- 2018-10-16 JP JP2020521362A patent/JP7275118B2/ja active Active
- 2018-10-16 EP EP23187608.7A patent/EP4279584A3/en active Pending
- 2018-10-16 CA CA3078962A patent/CA3078962A1/en active Pending
- 2018-10-16 US US16/161,542 patent/US10543263B2/en active Active
- 2018-10-16 CN CN201880080739.4A patent/CN111629735B/zh active Active
- 2018-10-16 EP EP18867942.7A patent/EP3697426B1/en active Active
- 2018-10-16 CN CN202410512405.7A patent/CN118345102A/zh active Pending
- 2018-10-16 WO PCT/US2018/056011 patent/WO2019079249A1/en not_active Ceased
- 2018-10-16 AU AU2018352245A patent/AU2018352245B2/en active Active
- 2018-10-16 ES ES18867942T patent/ES2958849T3/es active Active
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2020
- 2020-01-27 US US16/773,379 patent/US11878052B2/en active Active
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2023
- 2023-05-02 JP JP2023076196A patent/JP7696393B2/ja active Active
- 2023-12-04 US US18/528,012 patent/US20240108706A1/en active Pending
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2025
- 2025-06-09 JP JP2025095443A patent/JP2025138681A/ja active Pending
- 2025-09-10 AU AU2025230694A patent/AU2025230694A1/en active Pending
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