JP2021500376A5 - - Google Patents
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- JP2021500376A5 JP2021500376A5 JP2020523261A JP2020523261A JP2021500376A5 JP 2021500376 A5 JP2021500376 A5 JP 2021500376A5 JP 2020523261 A JP2020523261 A JP 2020523261A JP 2020523261 A JP2020523261 A JP 2020523261A JP 2021500376 A5 JP2021500376 A5 JP 2021500376A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- binder
- seq
- cancer
- directed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024006108A JP2024041975A (ja) | 2017-10-25 | 2024-01-18 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17198420.6 | 2017-10-25 | ||
| EP17198420 | 2017-10-25 | ||
| PCT/EP2018/079197 WO2019081595A2 (en) | 2017-10-25 | 2018-10-24 | DPP3 BINDER DIRECTED TO AND BINDING SPECIFIC DPP3 EPITOPES AND USE THEREOF IN THE PREVENTION OR TREATMENT OF OXIDATIVE STRESS ASSOCIATED DISEASES / CONDITIONS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024006108A Division JP2024041975A (ja) | 2017-10-25 | 2024-01-18 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021500376A JP2021500376A (ja) | 2021-01-07 |
| JP2021500376A5 true JP2021500376A5 (enExample) | 2021-11-25 |
| JP7424972B2 JP7424972B2 (ja) | 2024-01-30 |
Family
ID=60186108
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020523261A Active JP7424972B2 (ja) | 2017-10-25 | 2018-10-24 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
| JP2024006108A Pending JP2024041975A (ja) | 2017-10-25 | 2024-01-18 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024006108A Pending JP2024041975A (ja) | 2017-10-25 | 2024-01-18 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11530276B2 (enExample) |
| EP (2) | EP3700937A2 (enExample) |
| JP (2) | JP7424972B2 (enExample) |
| KR (2) | KR20250111243A (enExample) |
| CN (2) | CN118791621A (enExample) |
| AU (2) | AU2018356441C1 (enExample) |
| BR (1) | BR112020006563A2 (enExample) |
| CA (1) | CA3080251A1 (enExample) |
| IL (1) | IL274009B2 (enExample) |
| MX (1) | MX2020004271A (enExample) |
| MY (1) | MY202502A (enExample) |
| SG (1) | SG11202002594PA (enExample) |
| WO (1) | WO2019081595A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3700937A2 (en) * | 2017-10-25 | 2020-09-02 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 binder directed to and binding to specific dpp3-epitopes and its use in the prevention or treatment of diseases / acute conditions that are associated with oxidative stress |
| US20220211798A1 (en) * | 2018-12-21 | 2022-07-07 | 4TEEN4 Pharmaceuticals GmbH | Therapy guidance and/or therapy monitoring for a treatment with angiotensin-receptor-agonist and/or a precursor thereof |
| JP2022546061A (ja) * | 2019-08-30 | 2022-11-02 | ４ティーン４ ファーマシューティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | ショック症治療のための治療法の誘導および／または治療法の監視 |
| BR112022015215A2 (pt) * | 2020-02-27 | 2022-10-11 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 para orientação, monitoramento e estratificação de terapia de anticorpos nt-adm em pacientes com choque |
| EP3922993A1 (en) | 2020-06-12 | 2021-12-15 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 in patients infected with coronavirus |
| CN115769076A (zh) * | 2020-03-16 | 2023-03-07 | 4Teen4制药有限公司 | 感染冠状病毒的患者中的dpp3 |
| EP4633659A1 (en) | 2022-12-15 | 2025-10-22 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 inhibitor for improvement of pulmonary function in critically ill patients |
| CN115804836A (zh) * | 2022-12-27 | 2023-03-17 | 中国人民解放军海军特色医学中心 | 一种中枢小分子蛋白dpp3在制备降压药物中的应用 |
| JP2026513177A (ja) | 2023-03-29 | 2026-04-23 | ４ティーン４ ファーマシューティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 血圧低下を有する重症患者における心筋保護及び心筋傷害の予防のためのｄｐｐ３阻害剤 |
| WO2026046947A1 (en) | 2024-08-26 | 2026-03-05 | 4TEEN4 Pharmaceuticals GmbH | Anti-dpp3 antibody directed to and binding to dpp3 for the treatment of shock in extreme-critically ill patients |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| JPS6188884A (ja) | 1984-10-04 | 1986-05-07 | Sankyo Co Ltd | エンケフアリナ−ゼｂ阻害物質およびその製法 |
| AU634716B2 (en) | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ES2284161T3 (es) | 1990-01-12 | 2007-11-01 | Amgen Fremont Inc. | Generacion de anticuerpos xenogenicos. |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| CA2109602C (en) | 1990-07-10 | 2002-10-01 | Gregory P. Winter | Methods for producing members of specific binding pairs |
| AU3328493A (en) | 1991-12-17 | 1993-07-19 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| EP1212434A2 (en) | 1999-09-01 | 2002-06-12 | Incyte Genomics, Inc. | Human hydrolytic enzymes |
| BR0212256A (pt) | 2001-08-30 | 2004-08-31 | Biorexis Pharmaceutical Corp | Proteìnas de fusão de transferrina modificadas |
| DK2311432T3 (en) | 2002-06-07 | 2015-02-02 | Dyax Corp | Modified Kunitz domain polypeptides and their use in reducing ischemia or the onset of a systemic inflammatory response associated with a surgical procedure |
| WO2005040229A2 (en) | 2003-10-24 | 2005-05-06 | Avidia, Inc. | Ldl receptor class a and egf domain monomers and multimers |
| US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| WO2005106486A2 (en) | 2004-04-28 | 2005-11-10 | Bayer Healthcare Ag | Diagnostic and therapeutics for diseases associated with dipeptidyl-peptidase 3(dpp3) |
| WO2006032436A2 (en) | 2004-09-21 | 2006-03-30 | Nascacell Technologies Ag. | Use of microproteins as tryptase inhibitors |
| JP2006230318A (ja) | 2005-02-25 | 2006-09-07 | Maruishi Pharmaceutical Co Ltd | 関節リウマチの診断方法 |
| WO2007117444A2 (en) | 2006-03-31 | 2007-10-18 | Yinghe Hu | Protein detection by aptamers |
| CA2659082A1 (en) | 2006-06-07 | 2007-12-21 | Tethys Bioscience, Inc. | Markers associated with arteriovascular events and methods of use thereof |
| ATE527353T1 (de) | 2007-12-19 | 2011-10-15 | Affibody Ab | Pdgf-bindendes polypeptid aus protein a |
| MX359570B (es) | 2008-11-03 | 2018-10-01 | Molecular Partners Ag | Proteinas de union que inhiben la interaccion en el receptor de vegf-a. |
| WO2010093872A2 (en) | 2009-02-13 | 2010-08-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Molecular-based method of cancer diagnosis and prognosis |
| US20120020954A1 (en) * | 2009-03-30 | 2012-01-26 | Anat Achiron | Methods of predicting clinical course and treating multiple sclerosis |
| BR112012004314A2 (pt) | 2009-08-27 | 2016-11-29 | Covagen Ag | compostos de ligação a il-17 e usos medicinais desses compostos |
| KR101436222B1 (ko) | 2009-12-14 | 2014-09-01 | 쉴 프로테인즈 게엠베하 | 리간드 결합능력을 가진 헤테로-다량체 변형 유비퀴틴 단백질을 확인하는 방법 |
| AU2011263786B2 (en) | 2010-06-08 | 2014-11-13 | Astrazeneca Ab | Tear lipocalin muteins binding IL-4 R alpha |
| AU2014210447A1 (en) | 2013-01-28 | 2015-08-20 | Nuevas Alternativas Naturales S.A De C.V. | Compositions for the systemic treatment of pathological conditions resulting from oxidative stress and/or redox imbalance |
| CN104946646B (zh) * | 2014-03-25 | 2020-03-31 | 中国医学科学院基础医学研究所 | 用于预防和/或治疗埃博拉病毒性出血热的小核酸分子、dna分子、蛋白及应用 |
| MY200300A (en) | 2016-04-21 | 2023-12-19 | 4TEEN4 Pharmaceuticals GmbH | Methods for determining dpp3 and therapeutic methods |
| EP3700937A2 (en) * | 2017-10-25 | 2020-09-02 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 binder directed to and binding to specific dpp3-epitopes and its use in the prevention or treatment of diseases / acute conditions that are associated with oxidative stress |
-
2018
- 2018-10-24 EP EP18795970.5A patent/EP3700937A2/en active Pending
- 2018-10-24 BR BR112020006563-3A patent/BR112020006563A2/pt unknown
- 2018-10-24 EP EP25153152.1A patent/EP4527458A3/en active Pending
- 2018-10-24 SG SG11202002594PA patent/SG11202002594PA/en unknown
- 2018-10-24 KR KR1020257023507A patent/KR20250111243A/ko active Pending
- 2018-10-24 CN CN202410933184.0A patent/CN118791621A/zh active Pending
- 2018-10-24 US US16/758,881 patent/US11530276B2/en active Active
- 2018-10-24 MX MX2020004271A patent/MX2020004271A/es unknown
- 2018-10-24 KR KR1020207014841A patent/KR102835427B1/ko active Active
- 2018-10-24 WO PCT/EP2018/079197 patent/WO2019081595A2/en not_active Ceased
- 2018-10-24 MY MYPI2020002078A patent/MY202502A/en unknown
- 2018-10-24 IL IL274009A patent/IL274009B2/en unknown
- 2018-10-24 CN CN201880069013.0A patent/CN111542548B/zh active Active
- 2018-10-24 CA CA3080251A patent/CA3080251A1/en active Pending
- 2018-10-24 AU AU2018356441A patent/AU2018356441C1/en active Active
- 2018-10-24 JP JP2020523261A patent/JP7424972B2/ja active Active
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2022
- 2022-11-10 US US17/984,611 patent/US20230295344A1/en active Pending
-
2024
- 2024-01-18 JP JP2024006108A patent/JP2024041975A/ja active Pending
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2025
- 2025-03-06 AU AU2025201656A patent/AU2025201656A1/en active Pending