JP2021098740A5 - - Google Patents
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- Publication number
- JP2021098740A5 JP2021098740A5 JP2021038684A JP2021038684A JP2021098740A5 JP 2021098740 A5 JP2021098740 A5 JP 2021098740A5 JP 2021038684 A JP2021038684 A JP 2021038684A JP 2021038684 A JP2021038684 A JP 2021038684A JP 2021098740 A5 JP2021098740 A5 JP 2021098740A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- idh2
- trifluoromethyl
- composition according
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562263580P | 2015-12-04 | 2015-12-04 | |
| US62/263,580 | 2015-12-04 | ||
| US201662300721P | 2016-02-26 | 2016-02-26 | |
| US62/300,721 | 2016-02-26 | ||
| JP2018528735A JP6852073B2 (ja) | 2015-12-04 | 2016-12-02 | 悪性病変を処置する方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018528735A Division JP6852073B2 (ja) | 2015-12-04 | 2016-12-02 | 悪性病変を処置する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021098740A JP2021098740A (ja) | 2021-07-01 |
| JP2021098740A5 true JP2021098740A5 (https=) | 2021-10-21 |
Family
ID=57610403
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018528588A Expired - Fee Related JP6892448B2 (ja) | 2015-12-04 | 2016-12-02 | 悪性腫瘍の処置の方法 |
| JP2018528735A Active JP6852073B2 (ja) | 2015-12-04 | 2016-12-02 | 悪性病変を処置する方法 |
| JP2021038684A Pending JP2021098740A (ja) | 2015-12-04 | 2021-03-10 | 悪性病変を処置する方法 |
| JP2021089138A Withdrawn JP2021121636A (ja) | 2015-12-04 | 2021-05-27 | 悪性腫瘍の処置の方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018528588A Expired - Fee Related JP6892448B2 (ja) | 2015-12-04 | 2016-12-02 | 悪性腫瘍の処置の方法 |
| JP2018528735A Active JP6852073B2 (ja) | 2015-12-04 | 2016-12-02 | 悪性病変を処置する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021089138A Withdrawn JP2021121636A (ja) | 2015-12-04 | 2021-05-27 | 悪性腫瘍の処置の方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20200268726A1 (https=) |
| EP (2) | EP3383433A1 (https=) |
| JP (4) | JP6892448B2 (https=) |
| KR (2) | KR102924995B1 (https=) |
| CN (1) | CN108883184A (https=) |
| AU (2) | AU2016362425B2 (https=) |
| CA (2) | CA3007363A1 (https=) |
| ES (1) | ES2905915T3 (https=) |
| IL (4) | IL298663A (https=) |
| MA (1) | MA43374A (https=) |
| MX (2) | MX391229B (https=) |
| WO (2) | WO2017096150A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010223919B2 (en) | 2009-03-13 | 2016-03-31 | Les Laboratoires Servier | Methods and compositions for cell-proliferation-related disorders |
| EP3561077B1 (en) * | 2009-10-21 | 2022-12-21 | Les Laboratoires Servier | Methods for cell-proliferation-related disorders |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| US20150031627A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| KR20240010105A (ko) | 2014-03-14 | 2024-01-23 | 아지오스 파마슈티컬스 아이엔씨. | 치료적으로 활성인 화합물의 약제학적 조성물 |
| AU2015324158A1 (en) | 2014-09-29 | 2017-04-13 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| CN107531675A (zh) | 2015-02-04 | 2018-01-02 | 安吉奥斯医药品有限公司 | 治疗活性化合物及其使用方法 |
| CN108366980A (zh) | 2015-10-15 | 2018-08-03 | 安吉奥斯医药品有限公司 | 用于治疗恶性肿瘤的组合疗法 |
| PT3362066T (pt) | 2015-10-15 | 2021-11-16 | Celgene Corp | Terapia de combinação para tratar malignidades |
| SG11201803088PA (en) | 2015-10-15 | 2018-05-30 | Agios Pharmaceuticals Inc | Combination therapy for treating malignancies |
| US10695352B2 (en) | 2015-10-15 | 2020-06-30 | Celgene Corporation | Combination therapy for treating malignancies |
| MX392941B (es) | 2016-09-07 | 2025-03-24 | Celgene Corp | Composiciones para comprimidos. |
| WO2018204787A1 (en) | 2017-05-05 | 2018-11-08 | Memorial Sloan Kettering Cancer Center | Methods of treatment of myeloproliferative neoplasm |
| CN109467538A (zh) | 2017-09-07 | 2019-03-15 | 和记黄埔医药（上海）有限公司 | 环烯烃取代的杂芳环类化合物及其用途 |
| US11311527B2 (en) * | 2018-05-16 | 2022-04-26 | Forma Therapeutics, Inc. | Inhibiting mutant isocitrate dehydrogenase 1 (mIDH-1) |
| WO2019222553A1 (en) | 2018-05-16 | 2019-11-21 | Forma Therapeutics, Inc. | Inhibiting mutant idh-1 |
| US11013734B2 (en) | 2018-05-16 | 2021-05-25 | Forma Therapeutics, Inc. | Treating patients harboring an isocitrate dehydrogenase-1 (IDH-1) mutation |
| US10532047B2 (en) | 2018-05-16 | 2020-01-14 | Forma Therapeutics, Inc. | Solid forms of ((S)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile |
| US11013733B2 (en) * | 2018-05-16 | 2021-05-25 | Forma Therapeutics, Inc. | Inhibiting mutant isocitrate dehydrogenase 1 (mlDH-1) |
| US10980788B2 (en) | 2018-06-08 | 2021-04-20 | Agios Pharmaceuticals, Inc. | Therapy for treating malignancies |
| US12268690B2 (en) | 2018-07-27 | 2025-04-08 | Oregon Health & Science University | Treatments for mutations in acute myeloid leukemia |
| WO2020092894A1 (en) | 2018-11-02 | 2020-05-07 | Celgene Corporation | Solid forms of 2-methyl-1-[(4-[6-(trifluoromethyl) pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl) amino]propan-2-ol |
| WO2020092906A1 (en) | 2018-11-02 | 2020-05-07 | Celgene Corporation | Co-crystals of 2-methyl-1 -[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl) pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol, compositions and methods of use thereof |
| WO2020092915A1 (en) | 2018-11-02 | 2020-05-07 | Celgene Corporation | Solid dispersions for treatment of cancer |
| CA3133376A1 (en) * | 2018-11-30 | 2020-06-04 | Aptose Biosciences Inc. | Combination therapy with 2,3-dihydro-isoindole-1-one compounds and methods for treating patients with various mutations |
| WO2021097160A1 (en) | 2019-11-14 | 2021-05-20 | Celgene Corporation | Pediatric formulations for treatment of cancer |
| US12014835B2 (en) | 2020-02-19 | 2024-06-18 | Vanderbilt University | Methods for evaluating therapeutic benefit of combination therapies |
| WO2021168283A1 (en) * | 2020-02-19 | 2021-08-26 | Vanderbilt University | Therapeutic methods and compositions for treating cancer using braf and/or mek inhibitor combination therapy |
| CA3186380A1 (en) * | 2020-07-24 | 2022-01-27 | Molly ADAM | Spray drying of supersaturated solutions of api with acetic acid |
| WO2024229332A1 (en) * | 2023-05-03 | 2024-11-07 | Memorial Sloan-Kettering Cancer Center | Anti-cancer treatments and methods of use thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2290624C (en) | 1997-06-06 | 2006-12-05 | John W. Shell | Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs |
| US6635280B2 (en) | 1997-06-06 | 2003-10-21 | Depomed, Inc. | Extending the duration of drug release within the stomach during the fed mode |
| ES2270982T3 (es) | 2000-02-04 | 2007-04-16 | Depomed, Inc. | Forma de dosificacion de nucleo y carcasa que se aproxima a una liberacion del farmaco de orden cero. |
| US6723340B2 (en) | 2001-10-25 | 2004-04-20 | Depomed, Inc. | Optimal polymer mixtures for gastric retentive tablets |
| AU2010223919B2 (en) | 2009-03-13 | 2016-03-31 | Les Laboratoires Servier | Methods and compositions for cell-proliferation-related disorders |
| EP3561077B1 (en) | 2009-10-21 | 2022-12-21 | Les Laboratoires Servier | Methods for cell-proliferation-related disorders |
| NZ627096A (en) * | 2012-01-06 | 2017-02-24 | Agios Pharmaceuticals Inc | Triazinyl compounds and their methods of use |
| US9474779B2 (en) * | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| JP2015512630A (ja) * | 2012-03-12 | 2015-04-30 | メモリアル スローン−ケタリング キャンサー センター | 急性骨髄性白血病の診断、予後、及び治療用の方法及び組成物 |
| MY185687A (en) | 2013-07-11 | 2021-05-30 | Agios Pharmaceuticals Inc | N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as idh2 mutants inhibitors for the treatment of cancer |
| TWI666208B (zh) * | 2013-08-02 | 2019-07-21 | 美商阿吉斯藥品有限公司 | 治療活性化合物及其使用方法（三） |
| CA2842635A1 (en) | 2014-01-20 | 2015-07-20 | University Health Network | Pre-cancerous cells and their identification in the prevention and treatment of cancer |
| WO2015127172A1 (en) * | 2014-02-20 | 2015-08-27 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| WO2015127173A1 (en) * | 2014-02-20 | 2015-08-27 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| BR122023021436A2 (pt) | 2014-03-14 | 2023-12-12 | Les Laboratoires Servier | Formas cristalinas e composição farmacêutica de compostos terapeuticamente ativos |
| KR20240010105A (ko) * | 2014-03-14 | 2024-01-23 | 아지오스 파마슈티컬스 아이엔씨. | 치료적으로 활성인 화합물의 약제학적 조성물 |
| AU2015324158A1 (en) | 2014-09-29 | 2017-04-13 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| CN107531675A (zh) | 2015-02-04 | 2018-01-02 | 安吉奥斯医药品有限公司 | 治疗活性化合物及其使用方法 |
| CA2993615A1 (en) | 2015-08-05 | 2017-02-09 | Agios Pharmaceuticals, Inc. | Methods of preparing 6-(aryl or heteroaryl)-1,3,5-triazine-2,4-diols and 6-(aryl or heteroaryl)-1,3,5-triazine-2,4-diamines |
-
2016
- 2016-12-02 IL IL298663A patent/IL298663A/en unknown
- 2016-12-02 ES ES16816809T patent/ES2905915T3/es active Active
- 2016-12-02 KR KR1020187019185A patent/KR102924995B1/ko active Active
- 2016-12-02 MX MX2018006745A patent/MX391229B/es unknown
- 2016-12-02 WO PCT/US2016/064600 patent/WO2017096150A1/en not_active Ceased
- 2016-12-02 EP EP16816817.7A patent/EP3383433A1/en not_active Withdrawn
- 2016-12-02 MX MX2018006831A patent/MX380596B/es unknown
- 2016-12-02 KR KR1020187018928A patent/KR20180086255A/ko not_active Ceased
- 2016-12-02 US US15/781,019 patent/US20200268726A1/en not_active Abandoned
- 2016-12-02 JP JP2018528588A patent/JP6892448B2/ja not_active Expired - Fee Related
- 2016-12-02 IL IL299563A patent/IL299563A/en unknown
- 2016-12-02 US US15/368,439 patent/US10188656B2/en active Active
- 2016-12-02 AU AU2016362425A patent/AU2016362425B2/en active Active
- 2016-12-02 CN CN201680080463.0A patent/CN108883184A/zh active Pending
- 2016-12-02 AU AU2016363011A patent/AU2016363011B2/en not_active Ceased
- 2016-12-02 JP JP2018528735A patent/JP6852073B2/ja active Active
- 2016-12-02 CA CA3007363A patent/CA3007363A1/en active Pending
- 2016-12-02 WO PCT/US2016/064832 patent/WO2017096309A1/en not_active Ceased
- 2016-12-02 MA MA043374A patent/MA43374A/fr unknown
- 2016-12-02 CA CA3007218A patent/CA3007218A1/en not_active Abandoned
- 2016-12-02 EP EP16816809.4A patent/EP3383400B1/en active Active
-
2018
- 2018-06-03 IL IL259787A patent/IL259787A/en unknown
- 2018-06-03 IL IL259783A patent/IL259783A/en unknown
-
2021
- 2021-03-10 JP JP2021038684A patent/JP2021098740A/ja active Pending
- 2021-05-12 US US17/318,606 patent/US20220000878A1/en not_active Abandoned
- 2021-05-27 JP JP2021089138A patent/JP2021121636A/ja not_active Withdrawn
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