JP2021006549A5 - - Google Patents
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- JP2021006549A5 JP2021006549A5 JP2020164335A JP2020164335A JP2021006549A5 JP 2021006549 A5 JP2021006549 A5 JP 2021006549A5 JP 2020164335 A JP2020164335 A JP 2020164335A JP 2020164335 A JP2020164335 A JP 2020164335A JP 2021006549 A5 JP2021006549 A5 JP 2021006549A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- complex compound
- acceptable salt
- compound according
- molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022192575A JP2023025151A (ja) | 2015-08-11 | 2022-12-01 | 多リガンド－薬物複合体及びその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510489556.6A CN106466485B (zh) | 2015-08-11 | 2015-08-11 | 一种具有细胞内吞介导功能的靶向配体-药物偶联体 |
| CN201510489560.2 | 2015-08-11 | ||
| CN201510489556.6 | 2015-08-11 | ||
| CN201510489560.2A CN106466484B (zh) | 2015-08-11 | 2015-08-11 | 一种具有细胞内吞介导功能的多靶向配体-药物偶联体 |
| JP2017568345A JP6772199B2 (ja) | 2015-08-11 | 2016-08-11 | 多リガンド−薬物複合体及びその使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017568345A Division JP6772199B2 (ja) | 2015-08-11 | 2016-08-11 | 多リガンド−薬物複合体及びその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022192575A Division JP2023025151A (ja) | 2015-08-11 | 2022-12-01 | 多リガンド－薬物複合体及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021006549A JP2021006549A (ja) | 2021-01-21 |
| JP2021006549A5 true JP2021006549A5 (https=) | 2021-03-04 |
| JP7573401B2 JP7573401B2 (ja) | 2024-10-25 |
Family
ID=57983917
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017568345A Active JP6772199B2 (ja) | 2015-08-11 | 2016-08-11 | 多リガンド−薬物複合体及びその使用 |
| JP2020164335A Active JP7573401B2 (ja) | 2015-08-11 | 2020-09-30 | 多リガンド－薬物複合体及びその使用 |
| JP2022192575A Pending JP2023025151A (ja) | 2015-08-11 | 2022-12-01 | 多リガンド－薬物複合体及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017568345A Active JP6772199B2 (ja) | 2015-08-11 | 2016-08-11 | 多リガンド−薬物複合体及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022192575A Pending JP2023025151A (ja) | 2015-08-11 | 2022-12-01 | 多リガンド－薬物複合体及びその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11571480B2 (https=) |
| EP (1) | EP3334500B1 (https=) |
| JP (3) | JP6772199B2 (https=) |
| KR (2) | KR102464778B1 (https=) |
| CN (3) | CN112263683A (https=) |
| AU (2) | AU2016305703B2 (https=) |
| CA (1) | CA2987322C (https=) |
| DK (1) | DK3334500T3 (https=) |
| ES (1) | ES2877409T3 (https=) |
| MX (1) | MX381031B (https=) |
| RU (1) | RU2722449C2 (https=) |
| WO (1) | WO2017025057A1 (https=) |
| ZA (1) | ZA201707464B (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2445932B1 (en) | 2009-06-26 | 2018-02-28 | Soricimed Biopharma Inc. | Soricidin derived peptides and methods for the detection of trpv-6 cancers and drug delivery |
| JP6772199B2 (ja) * | 2015-08-11 | 2020-10-21 | コヒレント バイオファーマ | 多リガンド−薬物複合体及びその使用 |
| CA3083950A1 (en) * | 2017-12-01 | 2019-06-06 | Soricimed Biopharma Inc. | Trpv6 inhibitors and combination therapies for treating cancers |
| US11576981B2 (en) | 2017-12-06 | 2023-02-14 | Ontario Institute For Cancer Research (Oicr) | Acyl hydrazone linkers, methods and uses thereof |
| WO2019119141A1 (en) | 2017-12-22 | 2019-06-27 | Ontario Institute For Cancer Research (Oicr) | Heterocyclic acyl hydrazone linkers, methods and uses thereof |
| WO2019134018A1 (en) * | 2018-01-05 | 2019-07-11 | Telethon Kids Institute | Vaccine conjugates and uses thereof |
| AU2020214507B2 (en) * | 2019-01-30 | 2025-09-25 | Coherent Biopharma (Suzhou), Limited | Bi-ligand drug conjugate and use thereof |
| WO2021016392A1 (en) * | 2019-07-22 | 2021-01-28 | Purdue Research Foundation | Multivalent fibroblast-targeted agents and methods of use |
| CN114286867B (zh) * | 2019-08-20 | 2024-04-16 | 青岛华大智造科技有限责任公司 | 一种基于发光标记物光信号动力学及二次发光信号对多核苷酸进行测序的方法 |
| WO2021163701A1 (en) * | 2020-02-13 | 2021-08-19 | Escape Therapeutics, Inc. | Melanoma therapeutics |
| EP4274595A4 (en) * | 2021-01-07 | 2026-01-21 | Purdue Research Foundation | FOLATE RECEPTOR-TARGETED CONJUGATES, COMPOSITIONS AND ADMINISTRATION TO THE CENTRAL NERVOUS SYSTEM |
| CN117693365A (zh) * | 2021-06-25 | 2024-03-12 | 同宜医药（苏州）有限公司 | 配体药物偶联物及其应用 |
| CN116059392B (zh) * | 2021-09-03 | 2025-02-28 | 同宜医药（苏州）有限公司 | 配体偶联物及其应用 |
| JP2024533395A (ja) * | 2021-09-08 | 2024-09-12 | 同宜医藥（蘇州）有限公司 | 薬物製剤及びその製造方法と用途 |
| TW202327659A (zh) * | 2021-10-19 | 2023-07-16 | 大陸商同宜醫藥（蘇州）有限公司 | 偶聯體藥物製劑及其製備方法和用途 |
| CN116196408B (zh) * | 2021-12-30 | 2026-01-06 | 思格(苏州)生物科技有限公司 | 一种新型免疫佐剂及其制备方法和应用 |
| TW202404643A (zh) * | 2022-04-20 | 2024-02-01 | 大陸商同宜醫藥（蘇州）有限公司 | 化合物及用途 |
| WO2024099387A1 (zh) * | 2022-11-09 | 2024-05-16 | 同宜医药（苏州）有限公司 | 通过施用配体-药物偶联体治疗癌症 |
| CN120813385A (zh) * | 2023-03-23 | 2025-10-17 | 同宜医药（苏州）有限公司 | 通过施用配体-药物偶联体治疗卵巢癌 |
| WO2024222803A1 (zh) * | 2023-04-26 | 2024-10-31 | 同宜医药（苏州）有限公司 | 一种配体-药物偶联体在治疗癌症中的用途 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6093382A (en) * | 1998-05-16 | 2000-07-25 | Bracco Research Usa Inc. | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications |
| AU2002337954C1 (en) | 2001-10-22 | 2008-10-23 | The Scripps Research Institute | Integrin targeting compounds |
| EP1531846A4 (en) * | 2002-02-27 | 2006-04-19 | Us Gov Health & Human Serv | Conjugates of ligand, linker and cytotoxic agent and related compositions and methods of use |
| GB0209893D0 (en) | 2002-04-30 | 2002-06-05 | Molmed Spa | Conjugate |
| US7119168B2 (en) | 2002-11-18 | 2006-10-10 | Bioprospecting Nb Inc. | Paralytic peptide for use in neuromuscular therapy |
| EP1689443B1 (en) | 2003-12-05 | 2019-03-13 | Arrogene, Inc. | Polymalic acid-based multifunctional drug delivery system |
| WO2006060664A2 (en) | 2004-12-03 | 2006-06-08 | The Uab Research Foundation | Single-drug multi-ligand conjugates for targeted drug delivery |
| BRPI0615354A2 (pt) | 2005-08-19 | 2011-05-17 | Endocyte, Inc. | conjugado de liberação de fármaco de ligação de receptor, composição farmacêutica que o compreende, bem como seu uso |
| EP2354163A3 (en) | 2005-09-26 | 2013-04-24 | Medarex, Inc. | Conjugates of duocarmycin and anti-CD70 or anti-PSMA antibodies |
| JP2010503708A (ja) * | 2006-09-15 | 2010-02-04 | エンゾン ファーマスーティカルズ インコーポレイテッド | 多官能性リンカーを含む標的化ポリマープロドラッグ |
| US20080181852A1 (en) | 2007-01-29 | 2008-07-31 | Nitto Denko Corporation | Multi-functional Drug Carriers |
| CN101224306B (zh) * | 2008-02-20 | 2011-04-20 | 中山大学 | 叶酸-多肽复合物介导的靶向抗肿瘤前体药物及其制备方法 |
| EP2362729A1 (en) | 2008-11-17 | 2011-09-07 | Enzon Pharmaceuticals, Inc. | Releasable conjugates for nucleic acids delivery systems |
| WO2010059315A1 (en) * | 2008-11-18 | 2010-05-27 | Merrimack Pharmaceuticals, Inc. | Human serum albumin linkers and conjugates thereof |
| US9572895B2 (en) | 2010-08-06 | 2017-02-21 | The Board Of Trustees Of The University Of Illinois | Multiplexed supramolecular assemblies for non-viral delivery of genetic material |
| IN2014DN00101A (https=) | 2011-06-06 | 2015-05-15 | Starpharma Pty Ltd | |
| JP6355563B2 (ja) * | 2012-02-27 | 2018-07-11 | アムニクス オペレーティング インコーポレイテッド | Ｘｔｅｎ共役組成物およびそれを製造する方法 |
| CN103372199B (zh) * | 2012-04-16 | 2015-12-16 | 广州暨南大学医药生物技术研究开发中心 | 一种预防和治疗神经退行性疾病的新型脑部靶向制剂 |
| CA2873112A1 (en) | 2012-05-11 | 2013-11-14 | Alexander Krantz | Site-specific labeling and targeted delivery of proteins for the treatment of cancer |
| GB201211309D0 (en) | 2012-06-26 | 2012-08-08 | Fujifilm Mfg Europe Bv | Process for preparing membranes |
| CN104411337A (zh) | 2012-07-09 | 2015-03-11 | 基因泰克公司 | 包含抗cd79b抗体的免疫偶联物 |
| ES2781523T3 (es) * | 2012-07-12 | 2020-09-02 | Hangzhou Dac Biotech Co Ltd | Conjugados de moléculas de unión celular con agentes citotóxicos |
| WO2014089209A2 (en) | 2012-12-04 | 2014-06-12 | Abbvie, Inc. | Blood-brain barrier (bbb) penetrating dual specific binding proteins |
| EP2928502B1 (en) | 2012-12-05 | 2019-01-23 | Ruprecht-Karls-Universität Heidelberg | Conjugates of proteins and multivalent cell-penetrating peptides and their uses |
| US10150800B2 (en) * | 2013-03-15 | 2018-12-11 | Zyngenia, Inc. | EGFR-binding modular recognition domains |
| AU2014337317A1 (en) | 2013-10-15 | 2016-09-15 | Sorrento Therapeutics Inc. | Drug-conjugates with a targeting molecule and two different drugs |
| CN104784699B (zh) * | 2014-01-20 | 2019-05-03 | 博瑞生物医药（苏州）股份有限公司 | 叶酸受体结合配体-药物偶联物 |
| WO2016004043A1 (en) * | 2014-06-30 | 2016-01-07 | Blend Therapeutics, Inc. | Targeted conjugates and particles and formulations thereof |
| CN104667292B (zh) * | 2015-02-02 | 2017-09-05 | 北京大学 | 一种还原响应型药物偶联物纳米粒的制备及其应用 |
| EP3294810A4 (en) * | 2015-05-12 | 2019-01-02 | Blinkbio Inc. | Silicon based drug conjugates and methods of using same |
| JP6772199B2 (ja) * | 2015-08-11 | 2020-10-21 | コヒレント バイオファーマ | 多リガンド−薬物複合体及びその使用 |
| JP2020164335A (ja) * | 2019-03-28 | 2020-10-08 | イビデン株式会社 | ハニカム構造体 |
-
2016
- 2016-08-11 JP JP2017568345A patent/JP6772199B2/ja active Active
- 2016-08-11 ES ES16834681T patent/ES2877409T3/es active Active
- 2016-08-11 WO PCT/CN2016/094704 patent/WO2017025057A1/en not_active Ceased
- 2016-08-11 KR KR1020207016784A patent/KR102464778B1/ko active Active
- 2016-08-11 CN CN202011155574.8A patent/CN112263683A/zh active Pending
- 2016-08-11 US US15/751,541 patent/US11571480B2/en active Active
- 2016-08-11 AU AU2016305703A patent/AU2016305703B2/en active Active
- 2016-08-11 CN CN201680045855.3A patent/CN108135881B/zh active Active
- 2016-08-11 DK DK16834681.5T patent/DK3334500T3/da active
- 2016-08-11 CA CA2987322A patent/CA2987322C/en active Active
- 2016-08-11 MX MX2018001723A patent/MX381031B/es unknown
- 2016-08-11 RU RU2018104266A patent/RU2722449C2/ru active
- 2016-08-11 EP EP16834681.5A patent/EP3334500B1/en active Active
- 2016-08-11 KR KR1020187003716A patent/KR102301596B1/ko active Active
- 2016-08-11 CN CN202010115950.4A patent/CN111617250B/zh active Active
-
2017
- 2017-11-03 ZA ZA2017/07464A patent/ZA201707464B/en unknown
-
2019
- 2019-10-02 AU AU2019240611A patent/AU2019240611B2/en active Active
-
2020
- 2020-09-30 JP JP2020164335A patent/JP7573401B2/ja active Active
-
2022
- 2022-10-06 US US17/961,397 patent/US20240100175A1/en active Pending
- 2022-12-01 JP JP2022192575A patent/JP2023025151A/ja active Pending
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