JP2020537646A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020537646A5 JP2020537646A5 JP2020520468A JP2020520468A JP2020537646A5 JP 2020537646 A5 JP2020537646 A5 JP 2020537646A5 JP 2020520468 A JP2020520468 A JP 2020520468A JP 2020520468 A JP2020520468 A JP 2020520468A JP 2020537646 A5 JP2020537646 A5 JP 2020537646A5
- Authority
- JP
- Japan
- Prior art keywords
- terminal fragment
- nucleotide sequence
- intein
- sequence encoding
- selectable marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023200808A JP2024015079A (ja) | 2017-10-12 | 2023-11-28 | トランスジェニック選択方法および組成物 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762571672P | 2017-10-12 | 2017-10-12 | |
| US62/571,672 | 2017-10-12 | ||
| US201762608478P | 2017-12-20 | 2017-12-20 | |
| US62/608,478 | 2017-12-20 | ||
| US201862616281P | 2018-01-11 | 2018-01-11 | |
| US62/616,281 | 2018-01-11 | ||
| US201862624629P | 2018-01-31 | 2018-01-31 | |
| US62/624,629 | 2018-01-31 | ||
| PCT/US2018/055412 WO2019075200A1 (en) | 2017-10-12 | 2018-10-11 | METHODS AND COMPOSITIONS OF TRANSGENIC SELECTION |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023200808A Division JP2024015079A (ja) | 2017-10-12 | 2023-11-28 | トランスジェニック選択方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020537646A JP2020537646A (ja) | 2020-12-24 |
| JP2020537646A5 true JP2020537646A5 (https=) | 2021-11-25 |
| JP7394752B2 JP7394752B2 (ja) | 2023-12-08 |
Family
ID=66101179
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020520468A Active JP7394752B2 (ja) | 2017-10-12 | 2018-10-11 | トランスジェニック選択方法および組成物 |
| JP2023200808A Pending JP2024015079A (ja) | 2017-10-12 | 2023-11-28 | トランスジェニック選択方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023200808A Pending JP2024015079A (ja) | 2017-10-12 | 2023-11-28 | トランスジェニック選択方法および組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20200263197A1 (https=) |
| EP (1) | EP3694869A4 (https=) |
| JP (2) | JP7394752B2 (https=) |
| KR (1) | KR102729768B1 (https=) |
| CN (1) | CN111511759B (https=) |
| AU (1) | AU2018347421B2 (https=) |
| CA (1) | CA3079017A1 (https=) |
| WO (1) | WO2019075200A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11293021B1 (en) | 2016-06-23 | 2022-04-05 | Inscripta, Inc. | Automated cell processing methods, modules, instruments, and systems |
| US10011849B1 (en) | 2017-06-23 | 2018-07-03 | Inscripta, Inc. | Nucleic acid-guided nucleases |
| US9982279B1 (en) | 2017-06-23 | 2018-05-29 | Inscripta, Inc. | Nucleic acid-guided nucleases |
| JP2020530979A (ja) | 2017-06-30 | 2020-11-05 | インスクリプタ， インコーポレイテッド | 自動細胞処理方法、モジュール、機器及びシステム |
| US10557216B2 (en) | 2018-04-24 | 2020-02-11 | Inscripta, Inc. | Automated instrumentation for production of T-cell receptor peptide libraries |
| US10858761B2 (en) | 2018-04-24 | 2020-12-08 | Inscripta, Inc. | Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells |
| CA3108767A1 (en) | 2018-06-30 | 2020-01-02 | Inscripta, Inc. | Instruments, modules, and methods for improved detection of edited sequences in live cells |
| US11142740B2 (en) | 2018-08-14 | 2021-10-12 | Inscripta, Inc. | Detection of nuclease edited sequences in automated modules and instruments |
| US11214781B2 (en) | 2018-10-22 | 2022-01-04 | Inscripta, Inc. | Engineered enzyme |
| US11001831B2 (en) * | 2019-03-25 | 2021-05-11 | Inscripta, Inc. | Simultaneous multiplex genome editing in yeast |
| AU2020247900A1 (en) | 2019-03-25 | 2021-11-04 | Inscripta, Inc. | Simultaneous multiplex genome editing in yeast |
| AU2020288623A1 (en) | 2019-06-06 | 2022-01-06 | Inscripta, Inc. | Curing for recursive nucleic acid-guided cell editing |
| US11203762B2 (en) | 2019-11-19 | 2021-12-21 | Inscripta, Inc. | Methods for increasing observed editing in bacteria |
| AU2020407048A1 (en) | 2019-12-18 | 2022-06-09 | Inscripta, Inc. | Cascade/dCas3 complementation assays for in vivo detection of nucleic acid-guided nuclease edited cells |
| US11225674B2 (en) | 2020-01-27 | 2022-01-18 | Inscripta, Inc. | Electroporation modules and instrumentation |
| US20210332388A1 (en) | 2020-04-24 | 2021-10-28 | Inscripta, Inc. | Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells |
| US11787841B2 (en) | 2020-05-19 | 2023-10-17 | Inscripta, Inc. | Rationally-designed mutations to the thrA gene for enhanced lysine production in E. coli |
| US11299731B1 (en) | 2020-09-15 | 2022-04-12 | Inscripta, Inc. | CRISPR editing to embed nucleic acid landing pads into genomes of live cells |
| US11512297B2 (en) | 2020-11-09 | 2022-11-29 | Inscripta, Inc. | Affinity tag for recombination protein recruitment |
| AU2021415461A1 (en) | 2021-01-04 | 2023-08-17 | Inscripta, Inc. | Mad nucleases |
| EP4274890A4 (en) | 2021-01-07 | 2024-11-27 | Inscripta, Inc. | MAD-NUCLEASES |
| US11884924B2 (en) | 2021-02-16 | 2024-01-30 | Inscripta, Inc. | Dual strand nucleic acid-guided nickase editing |
| US20240124850A1 (en) | 2021-03-03 | 2024-04-18 | Shape Therapeutics Inc. | Auxotrophic Cells for Virus Production and Compositions and Methods of Making |
| WO2023027170A1 (ja) * | 2021-08-27 | 2023-03-02 | 国立大学法人 東京医科歯科大学 | タンパク質の翻訳制御システム |
| WO2023027169A1 (ja) * | 2021-08-27 | 2023-03-02 | 国立大学法人 東京医科歯科大学 | 生細胞の選別システム |
| CN116063546B (zh) * | 2021-10-29 | 2026-01-16 | 中科辅酶医科技(深圳)有限公司 | 一种基于共振能量转移的全遗传编码nad+蛋白探针及其制备方法和应用 |
| EP4473123A4 (en) * | 2022-02-01 | 2026-03-11 | Shape Therapeutics Inc | STABLE CELL LINES FOR INDUCIBLE VAAR VIRION PRODUCTION |
| CN114686440B (zh) * | 2022-05-31 | 2022-09-27 | 南京艾尔普再生医学科技有限公司 | 一种低免疫原性iPSC细胞的制备方法、低免疫原性iPSC细胞及组合物 |
| CN115896147B (zh) * | 2022-10-11 | 2023-10-03 | 态创生物科技(广州)有限公司 | 内含肽进化系统和方法、对应的突变质粒和报告质粒 |
| WO2024216202A2 (en) * | 2023-04-13 | 2024-10-17 | The Regents Of The University Of California | Fret biosensor recombinant proteins |
| US20250154517A1 (en) * | 2023-09-22 | 2025-05-15 | Ut-Battelle, Llc | System for plant co-transformation and methods of use |
| CN120923600A (zh) * | 2024-05-09 | 2025-11-11 | 福建医科大学 | 一种超稳定红色荧光蛋白 |
| WO2026044087A1 (en) | 2024-08-21 | 2026-02-26 | Shape Therapeutics Inc. | Increased cellular stability for aav production |
| WO2026073032A1 (en) | 2024-09-27 | 2026-04-02 | Shape Therapeutics Inc. | Constructs for improved aav production |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10113174A (ja) * | 1996-10-08 | 1998-05-06 | Amashiyamu Kk | ヒトシトクロムｐ−４５０とヒトシトクロムｐ−４５０還元酵素の同時製造方法 |
| US6858775B1 (en) * | 1999-05-24 | 2005-02-22 | New England Biolabs, Inc. | Method for generating split, non-transferable genes that are able to express an active protein product |
| DE60036942T2 (de) * | 1999-05-24 | 2008-08-07 | New England Biolabs, Inc., Beverly | Verfahren zur herstellung von getrennten, nicht-übertragbaren genen, welche befähigt sind ein aktives proteinprodukt zu exprimieren |
| EP2395084B1 (en) * | 2002-01-08 | 2018-03-14 | Agrivida, Inc. | Transgenic plants expressing CIVPS or intein modified proteins and related method |
| AU2004315485A1 (en) * | 2003-10-24 | 2005-08-18 | The Regents Of The University Of California | Self-assembling split-fluorescent protein systems |
| MX2008000985A (es) * | 2005-07-21 | 2008-04-07 | Abbott Lab | Expresion de gen multiple que incluye construcciones y metodos sorf (cuadro de lectura abierta simple) con poliproteinas, pro-proteinas y proteolisis. |
| JP5801207B2 (ja) * | 2009-02-27 | 2015-10-28 | ノバルティス アーゲー | ２種類の選択マーカーを含む発現ベクター系 |
| KR102096534B1 (ko) * | 2011-09-28 | 2020-04-03 | 에라 바이오테크, 에스.에이. | 분할된 인테인 및 그의 이용 |
-
2018
- 2018-10-11 KR KR1020207013411A patent/KR102729768B1/ko active Active
- 2018-10-11 US US16/755,065 patent/US20200263197A1/en active Pending
- 2018-10-11 AU AU2018347421A patent/AU2018347421B2/en active Active
- 2018-10-11 CA CA3079017A patent/CA3079017A1/en active Pending
- 2018-10-11 EP EP18867279.4A patent/EP3694869A4/en active Pending
- 2018-10-11 CN CN201880078542.7A patent/CN111511759B/zh active Active
- 2018-10-11 WO PCT/US2018/055412 patent/WO2019075200A1/en not_active Ceased
- 2018-10-11 JP JP2020520468A patent/JP7394752B2/ja active Active
-
2023
- 2023-11-28 JP JP2023200808A patent/JP2024015079A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020537646A5 (https=) | ||
| US20230279389A1 (en) | Recombinant nucleic acid molecule and application thereof in preparation of circular rna | |
| KR102884236B1 (ko) | Rna-가이드된 전사 조절 | |
| AU2014265608B2 (en) | Intracellular translation of circular RNA | |
| CA2678055C (en) | Rna interference tags | |
| US8017755B2 (en) | RNA-based transcriptional regulators | |
| JP2020537646A (ja) | トランスジェニック選択方法および組成物 | |
| US10294478B2 (en) | Aptamer modulators of estrogen receptors | |
| JP7770447B2 (ja) | タウの播種または凝集の遺伝的修飾因子を同定するためのｃｒｉｓｐｒ／ｃａｓスクリーニングプラットフォーム | |
| JP7389135B2 (ja) | タウ凝集に関連する遺伝的脆弱性を明らかにするためのｃｒｉｓｐｒ／ｃａｓドロップアウトスクリーニングプラットフォーム | |
| Lin et al. | Global profiling of Rbm24 bound RNAs uncovers a multi-tasking RNA binding protein | |
| CN101684478B (zh) | 一种串联表达小干扰rna重组慢病毒载体的构建方法 | |
| CN102245766B (zh) | 采用RNP基序构建蛋白应答shRNA/RNAi控制体系 | |
| JP2026511240A (ja) | 単離ヌクレアーゼ及びその使用 | |
| KR101921522B1 (ko) | miRNA의 표적 유전자 검증용 DNA 구조체 | |
| WO2006071884A2 (en) | Oligonucleotide based therapeutics | |
| US7504492B2 (en) | RNA polymerase III promoter, process for producing the same and method of using the same | |
| CN104560996B (zh) | 一种抑制小鼠GH基因表达的shRNA的载体及其应用 | |
| CN104404070A (zh) | 抑制小鼠MSTN表达的方法及相应MSTN shRNA片段 | |
| WO2007010840A1 (ja) | 多重shRNA発現ベクター | |
| KR20250166293A (ko) | 단리된 트랜스포사제 및 이의 용도 | |
| Biagi et al. | A Short 63-Nucleotide Element Promotes Efficient circRNA Translation | |
| Merle | Identification of miRNA pathway genes using a novel approach for identification of trans-factors acting on cis-regulatory elements in the 3′ UTR | |
| US9777277B2 (en) | Organic small hairpin RNAs | |
| Otto | Deciphering principles of recognition of human immunodeficiency virus (HIV) splice sites |