JP2020536874A5 - - Google Patents

Download PDF

Info

Publication number
JP2020536874A5
JP2020536874A5 JP2020519353A JP2020519353A JP2020536874A5 JP 2020536874 A5 JP2020536874 A5 JP 2020536874A5 JP 2020519353 A JP2020519353 A JP 2020519353A JP 2020519353 A JP2020519353 A JP 2020519353A JP 2020536874 A5 JP2020536874 A5 JP 2020536874A5
Authority
JP
Japan
Prior art keywords
group
probe
aliphatic
aromatic
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020519353A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020536874A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/054242 external-priority patent/WO2019070906A1/en
Publication of JP2020536874A publication Critical patent/JP2020536874A/ja
Publication of JP2020536874A5 publication Critical patent/JP2020536874A5/ja
Pending legal-status Critical Current

Links

JP2020519353A 2017-10-04 2018-10-03 異物代謝に関与する酵素を選択的に特性評価するためのプローブ、ならびにその製造方法および使用方法 Pending JP2020536874A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762568151P 2017-10-04 2017-10-04
US62/568,151 2017-10-04
US201762591697P 2017-11-28 2017-11-28
US62/591,697 2017-11-28
PCT/US2018/054242 WO2019070906A1 (en) 2017-10-04 2018-10-03 PROBE FOR SELECTIVELY CHARACTERIZING ENZYMES INVOLVED IN XENOBIOTIC METABOLISM AND METHOD FOR MANUFACTURING AND USING SAME

Publications (2)

Publication Number Publication Date
JP2020536874A JP2020536874A (ja) 2020-12-17
JP2020536874A5 true JP2020536874A5 (https=) 2021-10-28

Family

ID=64270938

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020519353A Pending JP2020536874A (ja) 2017-10-04 2018-10-03 異物代謝に関与する酵素を選択的に特性評価するためのプローブ、ならびにその製造方法および使用方法

Country Status (9)

Country Link
US (2) US11345950B2 (https=)
EP (1) EP3692014B1 (https=)
JP (1) JP2020536874A (https=)
KR (1) KR20200067855A (https=)
CN (1) CN111433176B (https=)
CA (1) CA3077422A1 (https=)
IL (1) IL273630A (https=)
SG (1) SG11202002913QA (https=)
WO (2) WO2019070906A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023012556A (ja) * 2019-06-14 2023-01-26 株式会社同仁化学研究所 細胞滞留性蛍光化合物並びにそれを用いた細胞の染色方法及び高感度検出方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294326B1 (en) 1997-11-07 2001-09-25 Abbott Laboratories Analyte detection process using dual labeled probes
JP2004029009A (ja) * 1998-12-15 2004-01-29 Hitachi Software Eng Co Ltd バイオチップ
AR026748A1 (es) * 1999-12-08 2003-02-26 Vertex Pharma Un compuesto inhibidor de caspasas, una composicion farmaceutica que lo comprende, un metodo para la sintesis del mismo y un compuesto intermediario paradicha sintesis
CA2403296A1 (en) 2000-04-10 2001-10-18 Benjamin F. Cravatt Proteomic analysis using activity-based probe libraries
WO2004033397A2 (en) 2002-10-09 2004-04-22 Activx Biosciences, Inc. Activity-based probes, and methods of their preparation and use
JP2004357706A (ja) * 2003-05-13 2004-12-24 Kitakyushu Foundation For The Advancement Of Industry Science & Technology 酵素活性検出用基板及びそれを用いた酵素活性の検出方法
US7736911B2 (en) 2004-04-15 2010-06-15 Albert Einstein College Of Medicine Of Yeshiva University Activity-based probes for protein tyrosine phosphatases
JP2006029954A (ja) * 2004-07-15 2006-02-02 Olympus Corp 生体関連物質検出用プローブ及び生体関連物質検出用固相化担体、並びに生体関連物質検出方法
US20110020837A1 (en) 2009-07-07 2011-01-27 Universiteit Utrecht Holding B.V. Method for isolating or identifying a target protein interacting with a lipid in a cell
EP2482077A1 (en) 2011-01-28 2012-08-01 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Seed trait prediction by activity-based protein profiling
WO2014031498A1 (en) 2012-08-18 2014-02-27 Academia Sinica Cell-permeable probes for identification and imaging of sialidases
CN105473735A (zh) * 2013-08-19 2016-04-06 拜恩科技诊断有限责任公司 用于肿瘤分子亚型分型的方法和试剂盒
WO2017221270A1 (en) 2016-06-22 2017-12-28 Regional Centre For Biotechnology Conjugated anti-proliferative drug nano-particles and process for preparation thereof

Similar Documents

Publication Publication Date Title
JP2019516821A5 (https=)
JP2012006935A (ja) 蛍光タグ付きリガンド
US8835000B2 (en) High-density fluorescent dye clusters
JP2021529194A5 (https=)
JP2019516807A5 (https=)
US7977048B2 (en) Detection and quantification of analytes in solution using polymers
US8541555B2 (en) Hydrazone-based and oxime-based fluorescent and chromophoric/pro-fluorescent and pro-chromophoric reagents and linkers
US6750346B2 (en) Stable near-infrared (NIR) marker dyes based on benzopyrylium-polymethines
CN108440475A (zh) 一种区分不同极性脂滴的比率型荧光探针及其制备方法和应用
RU2018138590A (ru) Ультраяркие димерные или полимерные красители со спейсерными линкерными группами
JP4824704B2 (ja) 非特異的タンパク質結合のためのクマリンべースのシアニン色素
US20130115651A1 (en) Fluorescent dyes
WO2008145609A1 (en) Method of making covalent conjugates with his-tagged proteins
JP2020536874A5 (https=)
US20060240455A1 (en) Oxazine derivatives
US20030088109A1 (en) Fluorescent dye
DE102013114848A1 (de) Markerfarbstoffe für UV- und kurzwellige Anregung mit hohem Stokes Shift auf der Basis von Benzoxazolen
JP2006500588A (ja) 複数のドナー及びアクセプターを有する蛍光標識試薬
JP5244596B2 (ja) タンパク質の検出方法及びそれに用いる蛍光色素
JP6319874B2 (ja) 新規化合物およびそれを利用した酸素濃度測定試薬
JP2006234772A (ja) タンパク質の検出方法及びそれに用いる蛍光色素
JPWO2008153223A1 (ja) 核酸と被験物質との結合親和性を測定するための組成物及びその利用
DE102020109362A1 (de) Fluoreszenzfarbstoffe mit hohem Stokes Shift auf der Basis von verbrückten Benzopyryliumsalzen
WO2013075285A1 (zh) 一类双苄基五甲川菁荧光染料、其制备方法及应用
JP6398055B2 (ja) 新規蛍光標識スフィンゴミエリン及びその利用