JP2020536524A - クリックベースのライゲーション - Google Patents

クリックベースのライゲーション Download PDF

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JP2020536524A
JP2020536524A JP2020518080A JP2020518080A JP2020536524A JP 2020536524 A JP2020536524 A JP 2020536524A JP 2020518080 A JP2020518080 A JP 2020518080A JP 2020518080 A JP2020518080 A JP 2020518080A JP 2020536524 A JP2020536524 A JP 2020536524A
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Japan
Prior art keywords
click
reaction
molecule
catalyst
methyl
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JP2020518080A
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English (en)
Japanese (ja)
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JP2020536524A5 (enExample
Inventor
フリシュムート トーマス
フリシュムート トーマス
セルジュコフ ザシャ
セルジュコフ ザシャ
Original Assignee
ベースクリック ゲーエムベーハー
ベースクリック ゲーエムベーハー
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Priority claimed from EP17194093.5A external-priority patent/EP3461832A1/en
Application filed by ベースクリック ゲーエムベーハー, ベースクリック ゲーエムベーハー filed Critical ベースクリック ゲーエムベーハー
Publication of JP2020536524A publication Critical patent/JP2020536524A/ja
Publication of JP2020536524A5 publication Critical patent/JP2020536524A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00—Reactions characterised by treatment of reaction samples
    • C12Q2523/10—Characterised by chemical treatment
    • C12Q2523/109—Characterised by chemical treatment chemical ligation between nucleic acids

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2020518080A 2017-09-29 2018-09-28 クリックベースのライゲーション Pending JP2020536524A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP17194093.5 2017-09-29
EP17194093.5A EP3461832A1 (en) 2017-09-29 2017-09-29 Click based ligation
EP18164071.5 2018-03-26
EP18164071 2018-03-26
PCT/EP2018/076495 WO2019063803A1 (en) 2017-09-29 2018-09-28 LIGATURE BASED ON A CLICK REACTION

Publications (2)

Publication Number Publication Date
JP2020536524A true JP2020536524A (ja) 2020-12-17
JP2020536524A5 JP2020536524A5 (enExample) 2021-11-04

Family

ID=63683912

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020518080A Pending JP2020536524A (ja) 2017-09-29 2018-09-28 クリックベースのライゲーション

Country Status (9)

Country Link
US (1) US20200361984A1 (enExample)
EP (1) EP3688004A1 (enExample)
JP (1) JP2020536524A (enExample)
KR (1) KR20200057708A (enExample)
CN (1) CN111183144A (enExample)
AU (1) AU2018338781B2 (enExample)
BR (1) BR112020004041A2 (enExample)
CA (1) CA3070514A1 (enExample)
WO (1) WO2019063803A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3842532A1 (en) 2019-12-23 2021-06-30 baseclick GmbH Method of amplifying mrnas and for preparing full length mrna libraries
IL290043B2 (en) 2019-12-23 2023-11-01 Baseclick Gmbh Method of amplifying mrnas and for preparing full length mrna libraries
CA3167380A1 (en) 2020-03-19 2021-09-23 Baseclick Gmbh Modified mrnas for vaccine development
EP4046651A1 (en) 2021-02-23 2022-08-24 baseclick GmbH Method for producing an mrna tumor vaccine
WO2023194331A1 (en) 2022-04-04 2023-10-12 Ecole Polytechnique Federale De Lausanne (Epfl) CONSTRUCTION OF SEQUENCING LIBRARIES FROM A RIBONUCLEIC ACID (RNA) USING TAILING AND LIGATION OF cDNA (TLC)
EP4585695A1 (en) * 2024-01-15 2025-07-16 Leica Microsystems CMS GmbH Label and marker for analysing a biological sample

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110210017A1 (en) * 2010-03-01 2011-09-01 Lai Rebecca Y Fabrication of electrochemical biosensors via click chemistry
JP2012523224A (ja) * 2009-04-09 2012-10-04 ベースクリック ゲーエムベーハー 不均一系触媒でのクリック化学
US20160347785A1 (en) * 2015-06-01 2016-12-01 Occidental College Methods, compositions, and kits using heterogeneous catalysts
US20170051338A1 (en) * 2014-04-29 2017-02-23 Baseclick Gmbh Self-assembly of dna origami: a new diagnostic tool

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA973642B (en) * 1996-04-26 1997-11-25 Merck & Co Inc DNA vaccine formulations.
ATE469135T1 (de) * 2002-05-30 2010-06-15 Scripps Research Inst Kupferkatalysierte ligierung von aziden und acetylenen
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
GB0706243D0 (en) * 2007-03-30 2007-05-09 Univ Southampton Modified nucleic acids
US8680260B2 (en) * 2009-05-15 2014-03-25 Riken 18F-labeled azide compound, reagent for 18F-labeling and method for 18F-labeling of alkyne compound using same
US20130046083A1 (en) * 2011-08-16 2013-02-21 Tom Brown Oligonucleotide ligation
WO2014016202A1 (en) * 2012-07-22 2014-01-30 Universität Basel Methods for catalytic alkylation of nucleic acids
US10155797B2 (en) * 2015-09-11 2018-12-18 The Governors Of The University Of Alberta Binding-induced DNA nanomachines

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012523224A (ja) * 2009-04-09 2012-10-04 ベースクリック ゲーエムベーハー 不均一系触媒でのクリック化学
US20110210017A1 (en) * 2010-03-01 2011-09-01 Lai Rebecca Y Fabrication of electrochemical biosensors via click chemistry
US20170051338A1 (en) * 2014-04-29 2017-02-23 Baseclick Gmbh Self-assembly of dna origami: a new diagnostic tool
US20160347785A1 (en) * 2015-06-01 2016-12-01 Occidental College Methods, compositions, and kits using heterogeneous catalysts

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ACC. CHEM. RES., vol. 48, JPN6022043094, 2015, pages 2516 - 2528, ISSN: 0005164883 *

Also Published As

Publication number Publication date
AU2018338781B2 (en) 2023-04-20
US20200361984A1 (en) 2020-11-19
CN111183144A (zh) 2020-05-19
KR20200057708A (ko) 2020-05-26
WO2019063803A1 (en) 2019-04-04
AU2018338781A1 (en) 2020-02-06
EP3688004A1 (en) 2020-08-05
CA3070514A1 (en) 2019-04-04
BR112020004041A2 (pt) 2020-09-08

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