KR20200057708A - 클릭 기반 연결 - Google Patents

클릭 기반 연결 Download PDF

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Publication number
KR20200057708A
KR20200057708A KR1020207007632A KR20207007632A KR20200057708A KR 20200057708 A KR20200057708 A KR 20200057708A KR 1020207007632 A KR1020207007632 A KR 1020207007632A KR 20207007632 A KR20207007632 A KR 20207007632A KR 20200057708 A KR20200057708 A KR 20200057708A
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KR
South Korea
Prior art keywords
click
reaction
catalyst
molecule
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020207007632A
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English (en)
Korean (ko)
Inventor
토마스 프리슈무트
자샤 제르튜코브
Original Assignee
바제클리크 게엠베하
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Priority claimed from EP17194093.5A external-priority patent/EP3461832A1/en
Application filed by 바제클리크 게엠베하 filed Critical 바제클리크 게엠베하
Publication of KR20200057708A publication Critical patent/KR20200057708A/ko
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00Reactions characterised by treatment of reaction samples
    • C12Q2523/10Characterised by chemical treatment
    • C12Q2523/109Characterised by chemical treatment chemical ligation between nucleic acids

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020207007632A 2017-09-29 2018-09-28 클릭 기반 연결 Ceased KR20200057708A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP17194093.5 2017-09-29
EP17194093.5A EP3461832A1 (en) 2017-09-29 2017-09-29 Click based ligation
EP18164071 2018-03-26
EP18164071.5 2018-03-26
PCT/EP2018/076495 WO2019063803A1 (en) 2017-09-29 2018-09-28 LIGATURE BASED ON A CLICK REACTION

Publications (1)

Publication Number Publication Date
KR20200057708A true KR20200057708A (ko) 2020-05-26

Family

ID=63683912

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207007632A Ceased KR20200057708A (ko) 2017-09-29 2018-09-28 클릭 기반 연결

Country Status (9)

Country Link
US (1) US20200361984A1 (enExample)
EP (1) EP3688004A1 (enExample)
JP (1) JP2020536524A (enExample)
KR (1) KR20200057708A (enExample)
CN (1) CN111183144A (enExample)
AU (1) AU2018338781B2 (enExample)
BR (1) BR112020004041A2 (enExample)
CA (1) CA3070514A1 (enExample)
WO (1) WO2019063803A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021130151A1 (en) 2019-12-23 2021-07-01 Baseclick Gmbh Method of amplifying mrnas and for preparing full length mrna libraries
EP3842532A1 (en) 2019-12-23 2021-06-30 baseclick GmbH Method of amplifying mrnas and for preparing full length mrna libraries
MX2022011504A (es) 2020-03-19 2022-10-07 Baseclick Gmbh Arnm modificados para desarrollo de vacunas.
EP4046651A1 (en) 2021-02-23 2022-08-24 baseclick GmbH Method for producing an mrna tumor vaccine
WO2023194331A1 (en) 2022-04-04 2023-10-12 Ecole Polytechnique Federale De Lausanne (Epfl) CONSTRUCTION OF SEQUENCING LIBRARIES FROM A RIBONUCLEIC ACID (RNA) USING TAILING AND LIGATION OF cDNA (TLC)
EP4585695A1 (en) * 2024-01-15 2025-07-16 Leica Microsystems CMS GmbH Label and marker for analysing a biological sample

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA973642B (en) * 1996-04-26 1997-11-25 Merck & Co Inc DNA vaccine formulations.
WO2003101972A1 (en) * 2002-05-30 2003-12-11 The Scripps Research Institute Copper-catalysed ligation of azides and acetylenes
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
GB0706243D0 (en) * 2007-03-30 2007-05-09 Univ Southampton Modified nucleic acids
EP2239053A1 (en) * 2009-04-09 2010-10-13 baseclick GmbH Click chemistry on heterogeneous catalysts
US8680260B2 (en) * 2009-05-15 2014-03-25 Riken 18F-labeled azide compound, reagent for 18F-labeling and method for 18F-labeling of alkyne compound using same
US20110210017A1 (en) * 2010-03-01 2011-09-01 Lai Rebecca Y Fabrication of electrochemical biosensors via click chemistry
US20130046083A1 (en) * 2011-08-16 2013-02-21 Tom Brown Oligonucleotide ligation
WO2014016202A1 (en) * 2012-07-22 2014-01-30 Universität Basel Methods for catalytic alkylation of nucleic acids
EP2940150A1 (en) * 2014-04-29 2015-11-04 Baseclick GmbH Self-assembly of DNA Origami: a new diganostic tool
WO2016196492A1 (en) * 2015-06-01 2016-12-08 Occidental College Methods, compositions, and kits using heterogeneous catalysts
US10155797B2 (en) * 2015-09-11 2018-12-18 The Governors Of The University Of Alberta Binding-induced DNA nanomachines

Also Published As

Publication number Publication date
CN111183144A (zh) 2020-05-19
EP3688004A1 (en) 2020-08-05
WO2019063803A1 (en) 2019-04-04
BR112020004041A2 (pt) 2020-09-08
JP2020536524A (ja) 2020-12-17
US20200361984A1 (en) 2020-11-19
CA3070514A1 (en) 2019-04-04
AU2018338781B2 (en) 2023-04-20
AU2018338781A1 (en) 2020-02-06

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