|
US5011912A
(en)
|
1986-12-19 |
1991-04-30 |
Immunex Corporation |
Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
|
|
ATE247129T1
(de)
|
1995-04-11 |
2003-08-15 |
Merck & Co Inc |
Biologisches verfahren zur herstellung von verbindungen auf der basis der dipeptiden
|
|
CA2283379A1
(en)
|
1997-03-05 |
1998-09-11 |
Michael G. Katze |
Novel screening methods to identify agents that selectively inhibit hepatitis c virus replication
|
|
EP1000084A4
(en)
|
1997-07-08 |
2003-03-26 |
Human Genome Sciences Inc |
123 HUMAN SECRETED PROTEINS
|
|
US6362007B1
(en)
|
1997-08-29 |
2002-03-26 |
Innogenetics N.V. |
Methylated, SMD homologous peptides, reactive with the antibodies from sera of living beings affected with systemic lupus erythematosus
|
|
US6413783B1
(en)
|
1997-09-18 |
2002-07-02 |
Meso Scale Technologies, Llc |
Assay sonication apparatus and methodology
|
|
US6436703B1
(en)
|
2000-03-31 |
2002-08-20 |
Hyseq, Inc. |
Nucleic acids and polypeptides
|
|
JP2004520803A
(ja)
|
2000-04-21 |
2004-07-15 |
コリクサ コーポレイション |
尋常性挫瘡の治療および診断のための組成物および方法
|
|
JP2004518437A
(ja)
|
2000-10-25 |
2004-06-24 |
ディアデクサス インコーポレーテッド |
肺特異的遺伝子およびタンパク質に関する組成物および方法
|
|
EP1349934A2
(en)
|
2000-11-20 |
2003-10-08 |
Diadexus, Inc. |
Compositions and methods relating to breast specific genes and proteins
|
|
US7528227B2
(en)
|
2004-03-23 |
2009-05-05 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Histone H2A peptide derivatives and uses thereof
|
|
US7163943B2
(en)
|
2001-09-21 |
2007-01-16 |
Reddy Us Therapeutics, Inc. |
Methods and compositions of novel triazine compounds
|
|
US7314974B2
(en)
|
2002-02-21 |
2008-01-01 |
Monsanto Technology, Llc |
Expression of microbial proteins in plants for production of plants with improved properties
|
|
US7393642B2
(en)
|
2003-07-17 |
2008-07-01 |
Chicago Community Foundation |
Methods and primers for diagnosing idiopathic congenital central hypoventilation syndrome
|
|
EP2345731B1
(en)
|
2003-09-30 |
2015-10-21 |
The Trustees of the University of Pennsylvania |
Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof
|
|
AU2005222776A1
(en)
|
2003-12-31 |
2005-09-29 |
Genimmune N.V. |
Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions
|
|
US7481997B1
(en)
|
2004-02-12 |
2009-01-27 |
Montana State University |
Snow mountain virus genome sequence, virus-like particles and methods of use
|
|
US20090075900A1
(en)
|
2004-04-08 |
2009-03-19 |
Sadakazu |
Therapeutic agent for motor neuron disease
|
|
WO2006034278A2
(en)
*
|
2004-09-21 |
2006-03-30 |
Matritech, Inc. |
Methods and compositions for detecting cancer using components of the u2 spliceosomal particle
|
|
EP1844148A2
(en)
|
2005-01-31 |
2007-10-17 |
University of Iowa Research Foundation |
Nucleic acid silencing of huntington's disease gene
|
|
WO2006133194A2
(en)
|
2005-06-06 |
2006-12-14 |
Vgx Pharmaceuticals, Inc |
Methods for treating viral infection with oral or injectible drug solution
|
|
US20080248099A1
(en)
|
2005-11-11 |
2008-10-09 |
Ishii Douglas N |
Method for Treating Disease or Disorder of Adult Central Nervous System Associated with Tissue Shrinkage or Atrophy by Administration of Insulin
|
|
PL2082225T3
(pl)
*
|
2006-09-20 |
2014-06-30 |
Univ Belfast |
Sposób określania czy komórka nowotworowa ma potencjał inwazyjny i/lub metastatyczny oraz środki modulujące złośliwą transformację
|
|
US20080188457A1
(en)
|
2007-02-02 |
2008-08-07 |
Braincells, Inc. |
Modulation of Neurogenesis with Biguanides and GSK3-beta Agents
|
|
US20090148866A1
(en)
*
|
2007-05-18 |
2009-06-11 |
Abbott Laboratories |
Antibodies and Improved Test Sample Handling Methods for Use in Assays for Myeloperoxidase
|
|
EP2164865A2
(en)
|
2007-06-13 |
2010-03-24 |
Hochschule Mannheim |
Compounds for the modulation of huntingtin aggregation, methods and means for identifying such compounds
|
|
US20090143418A1
(en)
|
2007-11-30 |
2009-06-04 |
The Regents Of The University Of Michigan |
Compositions and Methods for Preventing and Treating Hair Growth Cycle-Related Conditions
|
|
GB0809821D0
(en)
|
2008-05-30 |
2008-07-09 |
Univ Aberdeen |
Treatment and diagnosis of behavioural disorders
|
|
TW201034684A
(en)
|
2009-02-18 |
2010-10-01 |
Genentech Inc |
Method for inhibiting neurodegeneration
|
|
CA2757354A1
(en)
|
2009-04-02 |
2010-10-07 |
Laura P.W. Ranum |
Nucleotide repeat expansion-associated polypeptides and uses thereof
|
|
US20130053426A1
(en)
|
2009-04-17 |
2013-02-28 |
Yiqi Seow |
Composition For Delivery Of Genetic Material
|
|
CA2762351A1
(en)
|
2009-05-18 |
2010-11-25 |
Ottawa Hospital Research Institute |
Treatment of muscle disease characterized by insulin resistance
|
|
WO2011028912A2
(en)
|
2009-09-03 |
2011-03-10 |
University Of Tennessee Research Foundation |
A biomarker for neurodegeneration in neurological disease
|
|
KR101133243B1
(ko)
|
2009-10-29 |
2012-04-06 |
국립암센터 |
암의 진단 및 치료를 위한 ｅＩＦ３ｍ의 용도
|
|
EP2552435A1
(en)
|
2010-04-02 |
2013-02-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions comprising ampk activator (metformin/troglitazone) for the treatment of myotonic dystrophy type 1 (dm1)
|
|
EP2647706B1
(en)
*
|
2010-11-30 |
2023-05-17 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
|
|
PL3892295T3
(pl)
|
2011-05-24 |
2023-07-24 |
BioNTech SE |
Zindywidualizowane szczepionki przeciwnowotworowe
|
|
US9896729B2
(en)
|
2011-08-31 |
2018-02-20 |
The University Of Manchester |
Method for diagnosing a neurodegenerative disease
|
|
US9587014B2
(en)
|
2011-10-28 |
2017-03-07 |
Biogen International Neuroscience Gmbh |
TDP-43 specific binding molecules
|
|
WO2013130824A1
(en)
|
2012-02-29 |
2013-09-06 |
Sangamo Biosciences, Inc. |
Methods and compositions for treating huntington's disease
|
|
KR101417272B1
(ko)
|
2012-05-15 |
2014-07-14 |
경상대학교산학협력단 |
메트포민 및/또는 타이모퀴논을 포함하는 임신중 알코올 노출에 의한 신경질환 치료 또는 예방용 약학적 조성물
|
|
US20140100282A1
(en)
|
2012-10-10 |
2014-04-10 |
Patrick S L Wong |
Intranasal administration of pharmaceutical agents for treatment of neurological diseases
|
|
WO2014114303A1
(en)
|
2013-01-22 |
2014-07-31 |
Deutsches Zentrum Für Neurodegenerative Erkrankungen |
Dipeptide-repeat proteins as therapeutic target in neurodegenerative diseases with hexanucleotide repeat expansion
|
|
WO2014114660A1
(en)
|
2013-01-22 |
2014-07-31 |
Deutsches Zentrum Für Neurodegenerative Erkrankungen E.V. (Dzne) |
Dipeptide-repeat proteins as therapeutic target in neurodegenerative diseases with hexanucleotide repeat expansion
|
|
EP2948471A4
(en)
|
2013-01-24 |
2016-08-10 |
Mayo Foundation |
METHOD AND MATERIALS FOR DETECTING POSITIVE FRONTOTEMPORAL PAPER DEGENERATION BY C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSION OR AMYOTROPHATE LATERAL SCLEROSIS BY C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSION
|
|
WO2014159247A1
(en)
|
2013-03-14 |
2014-10-02 |
University Of Florida Research Foundation, Inc. |
Di-amino acid repeat-containing proteins associated with als
|
|
JP6806562B2
(ja)
|
2013-03-15 |
2021-01-06 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
ｅＩＦ２α経路の調節因子
|
|
WO2014186746A1
(en)
|
2013-05-16 |
2014-11-20 |
University Of Florida Research Foundation, Inc. |
HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION
|
|
EP2837390A1
(en)
|
2013-08-15 |
2015-02-18 |
Universitäts-Kinderspital beider Basel |
Combined Pharmaceutical Preparation for Use in Treating Neuromuscular Disorders
|
|
CA2990161A1
(en)
|
2014-08-13 |
2016-02-18 |
The Scripps Research Institute |
Treatment of c9ftd/als by targeting rna expanded repeat sequences
|
|
JP6508996B2
(ja)
*
|
2015-03-24 |
2019-05-08 |
東ソー株式会社 |
β−ＡＮＰによる心不全の検出方法
|
|
US20180088111A1
(en)
|
2015-04-14 |
2018-03-29 |
Bristol-Myers Squibb Company |
IMMUNOASSAY FOR SOLUBLE PROGRAMMED DEATH-1 (sPD-1) PROTEIN
|
|
WO2016191241A1
(en)
|
2015-05-27 |
2016-12-01 |
Mmc & Company Llc |
Dual target mitochondrial impinging pharmaceutical compositions affecting mitochondrial redox state and methods of treatment
|
|
US10509045B2
(en)
|
2015-05-29 |
2019-12-17 |
University Of Florida Research Foundation, Incorporated |
Methods for diagnosing Huntington's disease
|
|
FI3356827T3
(fi)
*
|
2015-10-02 |
2024-01-03 |
Univ Wuerzburg J Maximilians |
GDF-15 diagnostisena markkerina immuunivasteen vapauttajilla annetun hoidon hoitovasteen ennustamiseksi
|
|
US10940161B2
(en)
|
2016-04-04 |
2021-03-09 |
University Of Florida Research Foundation, Incorporated |
Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation
|
|
CN109715144A
(zh)
|
2016-08-18 |
2019-05-03 |
奥维德医疗公司 |
使用双胍类治疗发育障碍的方法
|
|
WO2018195110A1
(en)
|
2017-04-17 |
2018-10-25 |
University Of Florida Research Foundation, Incorporated |
Regolation of ran translation by pkr and eif2a-p pathways
|
|
EP3688020A4
(en)
|
2017-09-25 |
2021-07-14 |
University of Florida Research Foundation, Incorporated |
IMMUNOASSAYS FOR DETECTION OF RAN PROTEINS
|
|
AU2018342105B2
(en)
|
2017-09-26 |
2023-11-16 |
University Of Florida Research Foundation, Incorporated |
Use of metformin and analogs thereof to reduce ran protein levels in the treatment of neurological disorders
|
|
WO2019099732A1
(en)
|
2017-11-16 |
2019-05-23 |
Brainbox Solutions, Inc. |
Protein biomarker indicators of neurological injury and/or disease and methods of use thereof
|
|
EP3962518A1
(en)
|
2019-05-02 |
2022-03-09 |
Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) |
Immunogen for preventing or treating familial frontotemporal dementia (ftd) and/or amyotrophic lateral sclerosis (als)
|
|
EP3994159A4
(en)
|
2019-07-05 |
2023-08-09 |
University of Florida Research Foundation, Incorporated |
METHODS OF TREATING NEUROLOGICAL DISEASES ASSOCIATED WITH THE RAN PROTEIN
|
|
WO2021055880A1
(en)
|
2019-09-20 |
2021-03-25 |
University Of Florida Researchfoundation, Incorporated |
Detection of antibodies against ran proteins from serum and tissue lysates
|
|
WO2021061537A1
(en)
|
2019-09-23 |
2021-04-01 |
University Of Florida Research Foundation, Incorporated |
Vaccine therapy for ran protein diseases
|
|
EP4041756A4
(en)
|
2019-10-10 |
2023-11-01 |
University Of Florida Research Foundation, Incorporated |
RAN PROTEINS AS BIOMARKERS IN CAG/CTG EXPANSION DISORDERS
|
|
WO2021231887A1
(en)
|
2020-05-15 |
2021-11-18 |
University Of Florida Research Foundation, Incorporated |
Compositions and methods of detection of pre-symptomatic als
|
|
EP4440560A1
(en)
|
2021-12-01 |
2024-10-09 |
University Of Florida Research Foundation, Incorporated |
Small molecule inhibitors of repeat associated non-aug (ran) translation and combination therapies
|
|
WO2023164686A2
(en)
|
2022-02-28 |
2023-08-31 |
University Of Florida Researchfoundation, Incorporated |
Ran proteins in sporadic amyotrophic lateral sclerosis
|