|
US5011912A
(en)
|
1986-12-19 |
1991-04-30 |
Immunex Corporation |
Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
|
|
BR9608278A
(pt)
|
1995-04-11 |
1999-10-13 |
Merck & Co Inc |
Processo para produzir um intermediário de dipeptìdeo de um composto à base de dipeptìdeo
|
|
JP2001514508A
(ja)
|
1997-03-05 |
2001-09-11 |
ユニバーシティー オブ ワシントン |
C型肝炎ウイルスの複製を選択的に抑制する薬剤を同定するための新規なスクリーニング法
|
|
WO1999002546A1
(en)
|
1997-07-08 |
1999-01-21 |
Human Genome Sciences, Inc. |
123 human secreted proteins
|
|
AU751784B2
(en)
|
1997-08-29 |
2002-08-29 |
Innogenetics N.V. |
Methylated, SmD homologous peptides, reactive with the antibodies from sera of living beings affected with systemic lupus erythematosus
|
|
US6413783B1
(en)
|
1997-09-18 |
2002-07-02 |
Meso Scale Technologies, Llc |
Assay sonication apparatus and methodology
|
|
US6436703B1
(en)
|
2000-03-31 |
2002-08-20 |
Hyseq, Inc. |
Nucleic acids and polypeptides
|
|
CA2407352A1
(en)
|
2000-04-21 |
2001-11-01 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of acne vulgaris
|
|
US6846650B2
(en)
|
2000-10-25 |
2005-01-25 |
Diadexus, Inc. |
Compositions and methods relating to lung specific genes and proteins
|
|
US6855517B2
(en)
|
2000-11-20 |
2005-02-15 |
Diadexus, Inc. |
Compositions and methods relating to breast specific genes and proteins
|
|
US7528227B2
(en)
|
2004-03-23 |
2009-05-05 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Histone H2A peptide derivatives and uses thereof
|
|
US7163943B2
(en)
|
2001-09-21 |
2007-01-16 |
Reddy Us Therapeutics, Inc. |
Methods and compositions of novel triazine compounds
|
|
US7314974B2
(en)
|
2002-02-21 |
2008-01-01 |
Monsanto Technology, Llc |
Expression of microbial proteins in plants for production of plants with improved properties
|
|
US7393642B2
(en)
|
2003-07-17 |
2008-07-01 |
Chicago Community Foundation |
Methods and primers for diagnosing idiopathic congenital central hypoventilation syndrome
|
|
CN1856576B
(zh)
|
2003-09-30 |
2011-05-04 |
宾夕法尼亚州立大学托管会 |
腺伴随病毒(aav)进化支、序列、含有这些序列的载体及它们的应用
|
|
AU2005222776A1
(en)
|
2003-12-31 |
2005-09-29 |
Genimmune N.V. |
Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions
|
|
US7481997B1
(en)
|
2004-02-12 |
2009-01-27 |
Montana State University |
Snow mountain virus genome sequence, virus-like particles and methods of use
|
|
WO2005099741A1
(ja)
|
2004-04-08 |
2005-10-27 |
Noevir Co., Ltd. |
運動ニューロン疾患治療薬
|
|
US20060068434A1
(en)
*
|
2004-09-21 |
2006-03-30 |
Jay Stoerker |
Methods and compositions for detecting cancer using components of the U2 spliceosomal particle
|
|
EP1844148A2
(en)
|
2005-01-31 |
2007-10-17 |
University of Iowa Research Foundation |
Nucleic acid silencing of huntington's disease gene
|
|
US20090074721A1
(en)
|
2005-06-06 |
2009-03-19 |
Vgx Pharmaceuticals, Inc. |
Methods for treating viral infection with oral or injectibel drug solution
|
|
US20080248099A1
(en)
|
2005-11-11 |
2008-10-09 |
Ishii Douglas N |
Method for Treating Disease or Disorder of Adult Central Nervous System Associated with Tissue Shrinkage or Atrophy by Administration of Insulin
|
|
ES2453374T3
(es)
*
|
2006-09-20 |
2014-04-07 |
The Queen's University Of Belfast |
Método para determinar si una célula tumoral presenta potencial invasivo y/o metastásico, y agentes moduladores de la transformación maligna
|
|
WO2008097861A2
(en)
|
2007-02-02 |
2008-08-14 |
Braincells, Inc. |
MODULATION OF NEUROGENESIS WITH BIGUANIDES AND GSK3-ß AGENTS
|
|
US20090148866A1
(en)
*
|
2007-05-18 |
2009-06-11 |
Abbott Laboratories |
Antibodies and Improved Test Sample Handling Methods for Use in Assays for Myeloperoxidase
|
|
WO2008151833A2
(en)
|
2007-06-13 |
2008-12-18 |
Hochschule Mannheim |
Compounds for the modulation of huntingtin aggregation, methods and means for identifying such compounds
|
|
US20090143418A1
(en)
|
2007-11-30 |
2009-06-04 |
The Regents Of The University Of Michigan |
Compositions and Methods for Preventing and Treating Hair Growth Cycle-Related Conditions
|
|
GB0809821D0
(en)
|
2008-05-30 |
2008-07-09 |
Univ Aberdeen |
Treatment and diagnosis of behavioural disorders
|
|
TW201034684A
(en)
|
2009-02-18 |
2010-10-01 |
Genentech Inc |
Method for inhibiting neurodegeneration
|
|
CA2757354A1
(en)
|
2009-04-02 |
2010-10-07 |
Laura P.W. Ranum |
Nucleotide repeat expansion-associated polypeptides and uses thereof
|
|
EP3569254B1
(en)
|
2009-04-17 |
2022-07-20 |
Oxford University Innovation Limited |
Composition for delivery of genetic material
|
|
WO2010132982A1
(en)
|
2009-05-18 |
2010-11-25 |
Ottawa Hospital Research Institute |
Treatment of muscle disease characterized by insulin resistance
|
|
WO2011028912A2
(en)
|
2009-09-03 |
2011-03-10 |
University Of Tennessee Research Foundation |
A biomarker for neurodegeneration in neurological disease
|
|
KR101133243B1
(ko)
|
2009-10-29 |
2012-04-06 |
국립암센터 |
암의 진단 및 치료를 위한 eIF3m의 용도
|
|
US20130085169A1
(en)
|
2010-04-02 |
2013-04-04 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions comprising ampk activator (metformin/troglitazone) for the treatment of myotonic dystrophy type 1 (dm1)
|
|
TWI812066B
(zh)
|
2010-11-30 |
2023-08-11 |
日商中外製藥股份有限公司 |
具有鈣依存性的抗原結合能力之抗體
|
|
HRP20211595T1
(hr)
|
2011-05-24 |
2022-01-21 |
BioNTech SE |
Individualizirana cjepiva protiv raka
|
|
EP2751284B1
(en)
|
2011-08-31 |
2017-01-11 |
The University Of Manchester |
Method for diagnosing a neurodegenerative disease.
|
|
CA2853412C
(en)
|
2011-10-28 |
2021-05-04 |
University Of Zurich |
Tdp-43 specific binding molecules
|
|
CN108285491B
(zh)
|
2012-02-29 |
2021-08-10 |
桑格摩生物科学股份有限公司 |
治疗亨廷顿氏病的方法和组合物
|
|
KR101417272B1
(ko)
|
2012-05-15 |
2014-07-14 |
경상대학교산학협력단 |
메트포민 및/또는 타이모퀴논을 포함하는 임신중 알코올 노출에 의한 신경질환 치료 또는 예방용 약학적 조성물
|
|
US20140100282A1
(en)
|
2012-10-10 |
2014-04-10 |
Patrick S L Wong |
Intranasal administration of pharmaceutical agents for treatment of neurological diseases
|
|
WO2014114303A1
(en)
|
2013-01-22 |
2014-07-31 |
Deutsches Zentrum Für Neurodegenerative Erkrankungen |
Dipeptide-repeat proteins as therapeutic target in neurodegenerative diseases with hexanucleotide repeat expansion
|
|
PT2948777T
(pt)
|
2013-01-22 |
2019-09-26 |
Deutsches Zentrum Fuer Neurodegenerative Erkrankungen E V |
Proteínas de repetição por dipeptídeos como alvo terapêutico em doenças neurodegenerativas com expansão de hexanucleotídico repetido
|
|
EP2948471A4
(en)
|
2013-01-24 |
2016-08-10 |
Mayo Foundation |
METHOD AND MATERIALS FOR DETECTING POSITIVE FRONTOTEMPORAL PAPER DEGENERATION BY C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSION OR AMYOTROPHATE LATERAL SCLEROSIS BY C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSION
|
|
WO2014159247A1
(en)
*
|
2013-03-14 |
2014-10-02 |
University Of Florida Research Foundation, Inc. |
Di-amino acid repeat-containing proteins associated with als
|
|
CA2904794C
(en)
|
2013-03-15 |
2021-11-23 |
Peter Walter |
Modulators of the eif2alpha pathway
|
|
WO2014186746A1
(en)
|
2013-05-16 |
2014-11-20 |
University Of Florida Research Foundation, Inc. |
HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION
|
|
EP2837390A1
(en)
|
2013-08-15 |
2015-02-18 |
Universitäts-Kinderspital beider Basel |
Combined Pharmaceutical Preparation for Use in Treating Neuromuscular Disorders
|
|
WO2016025692A1
(en)
*
|
2014-08-13 |
2016-02-18 |
The Scripps Research Institute |
Treatment of c9ftd/als by targeting rna expanded repeat sequences
|
|
JP6508996B2
(ja)
|
2015-03-24 |
2019-05-08 |
東ソー株式会社 |
β−ANPによる心不全の検出方法
|
|
WO2016168143A1
(en)
|
2015-04-14 |
2016-10-20 |
Bristol-Myers Squibb Company |
IMMUNOASSAY FOR SOLUBLE PROGRAMMED DEATH-1 (sPD-1) PROTEIN
|
|
WO2016191241A1
(en)
|
2015-05-27 |
2016-12-01 |
Mmc & Company Llc |
Dual target mitochondrial impinging pharmaceutical compositions affecting mitochondrial redox state and methods of treatment
|
|
US10509045B2
(en)
|
2015-05-29 |
2019-12-17 |
University Of Florida Research Foundation, Incorporated |
Methods for diagnosing Huntington's disease
|
|
KR102621034B1
(ko)
|
2015-10-02 |
2024-01-03 |
율리우스-막시밀리안스 우니버지태트 뷔르츠부르크 |
면역 체크포인트 차단제를 이용한 치료의 임상적인 경과를 예측하기 위한 진단 마커로서의 gdf-15
|
|
US10940161B2
(en)
|
2016-04-04 |
2021-03-09 |
University Of Florida Research Foundation, Incorporated |
Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation
|
|
JP2019524834A
(ja)
|
2016-08-18 |
2019-09-05 |
オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics, Inc. |
ビグアナイド系による発達障害の治療方法
|
|
WO2018195110A1
(en)
|
2017-04-17 |
2018-10-25 |
University Of Florida Research Foundation, Incorporated |
Regolation of ran translation by pkr and eif2a-p pathways
|
|
JP2020535448A
(ja)
|
2017-09-25 |
2020-12-03 |
ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. |
Ranタンパク質の検出のための免役アッセイ
|
|
US11903910B2
(en)
|
2017-09-26 |
2024-02-20 |
University Of Florida Research Foundation, Incorporated |
Use of metformin and analogs thereof to reduce RAN protein levels in the treatment of neurological disorders
|
|
JP2021503610A
(ja)
|
2017-11-16 |
2021-02-12 |
ブレインボックス ソルーションズ、インコーポレイテッドBrainbox Solutions, Inc. |
神経損傷および/または疾患のタンパク質バイオマーカー指標及びその使用の方法
|
|
WO2020221937A1
(en)
|
2019-05-02 |
2020-11-05 |
Deutsches Zentrum Für Neurodegenerative Erkrankungen E.V. (Dzne) |
Immunogen for preventing or treating familial frontotemporal dementia (ftd) and/or amyotrophic lateral sclerosis (als)
|
|
US20220267776A1
(en)
|
2019-07-05 |
2022-08-25 |
University Of Florida Research Foundation, Incorporated |
Methods for treating ran protein-associated neurological diseases
|
|
WO2021055880A1
(en)
|
2019-09-20 |
2021-03-25 |
University Of Florida Researchfoundation, Incorporated |
Detection of antibodies against ran proteins from serum and tissue lysates
|
|
WO2021061537A1
(en)
|
2019-09-23 |
2021-04-01 |
University Of Florida Research Foundation, Incorporated |
Vaccine therapy for ran protein diseases
|
|
EP4041756A4
(en)
|
2019-10-10 |
2023-11-01 |
University Of Florida Research Foundation, Incorporated |
RAN PROTEINS AS BIOMARKERS IN CAG/CTG EXPANSION DISORDERS
|
|
US20230304088A1
(en)
|
2020-05-15 |
2023-09-28 |
University Of Florida Research Foundation, Incorporated |
Compositions and methods of detection of pre-symptomatic als
|
|
WO2023102111A1
(en)
|
2021-12-01 |
2023-06-08 |
University Of Florida Research Foundation, Incorporated |
Small molecule inhibitors of repeat associated non-aug (ran) translation and combination therapies
|
|
WO2023164686A2
(en)
|
2022-02-28 |
2023-08-31 |
University Of Florida Researchfoundation, Incorporated |
Ran proteins in sporadic amyotrophic lateral sclerosis
|