GB0809821D0 - Treatment and diagnosis of behavioural disorders - Google Patents

Treatment and diagnosis of behavioural disorders

Info

Publication number
GB0809821D0
GB0809821D0 GBGB0809821.2A GB0809821A GB0809821D0 GB 0809821 D0 GB0809821 D0 GB 0809821D0 GB 0809821 A GB0809821 A GB 0809821A GB 0809821 D0 GB0809821 D0 GB 0809821D0
Authority
GB
United Kingdom
Prior art keywords
treatment
diagnosis
behavioural
behavioural disorders
eif4e
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0809821.2A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Aberdeen
Grampian Health Board
Original Assignee
University of Aberdeen
Grampian Health Board
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Aberdeen, Grampian Health Board filed Critical University of Aberdeen
Priority to GBGB0809821.2A priority Critical patent/GB0809821D0/en
Publication of GB0809821D0 publication Critical patent/GB0809821D0/en
Priority to PCT/GB2009/001367 priority patent/WO2009144480A1/en
Priority to GB1021794.1A priority patent/GB2473575B/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention concerns the identification of a novel drug target for use in the treatment of behavioural dis order, hi particular, the invention provides compounds capable of modulating the expression, function and/or activity of eIF4E, for use in treating a behavioural disorder as well as methods of identifying the same.
GBGB0809821.2A 2008-05-30 2008-05-30 Treatment and diagnosis of behavioural disorders Ceased GB0809821D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GBGB0809821.2A GB0809821D0 (en) 2008-05-30 2008-05-30 Treatment and diagnosis of behavioural disorders
PCT/GB2009/001367 WO2009144480A1 (en) 2008-05-30 2009-05-29 Treatment and diagnosis of behavioural disorders
GB1021794.1A GB2473575B (en) 2008-05-30 2009-05-29 Diagnosis of autism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0809821.2A GB0809821D0 (en) 2008-05-30 2008-05-30 Treatment and diagnosis of behavioural disorders

Publications (1)

Publication Number Publication Date
GB0809821D0 true GB0809821D0 (en) 2008-07-09

Family

ID=39637839

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB0809821.2A Ceased GB0809821D0 (en) 2008-05-30 2008-05-30 Treatment and diagnosis of behavioural disorders
GB1021794.1A Expired - Fee Related GB2473575B (en) 2008-05-30 2009-05-29 Diagnosis of autism

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1021794.1A Expired - Fee Related GB2473575B (en) 2008-05-30 2009-05-29 Diagnosis of autism

Country Status (2)

Country Link
GB (2) GB0809821D0 (en)
WO (1) WO2009144480A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013503646A (en) 2009-09-08 2013-02-04 ラボラトリー コーポレイション オブ アメリカ ホールディングス Compositions and methods for diagnosing autism spectrum disorders
US10509045B2 (en) 2015-05-29 2019-12-17 University Of Florida Research Foundation, Incorporated Methods for diagnosing Huntington's disease
CA3019847A1 (en) * 2016-04-04 2017-10-12 University Of Florida Research Foundation, Incorporated Manipulation of eif3 to modulate repeat associated non-atg (ran) translation
WO2018195110A1 (en) 2017-04-17 2018-10-25 University Of Florida Research Foundation, Incorporated Regolation of ran translation by pkr and eif2a-p pathways
US11903910B2 (en) 2017-09-26 2024-02-20 University Of Florida Research Foundation, Incorporated Use of metformin and analogs thereof to reduce RAN protein levels in the treatment of neurological disorders
US20240052004A1 (en) * 2019-10-04 2024-02-15 Yale University Targeting cap-dependent translation to reduce seizures in mtor disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100150839A1 (en) * 2005-02-04 2010-06-17 Massachusetts Institute Of Technology Compositions and Methods for Modulating Cognitive Function

Also Published As

Publication number Publication date
GB2473575A (en) 2011-03-16
GB201021794D0 (en) 2011-02-02
WO2009144480A1 (en) 2009-12-03
GB2473575B (en) 2013-02-20

Similar Documents

Publication Publication Date Title
WO2009044173A3 (en) Methods of treating cancer using notch pathway inhibitors
WO2011038210A3 (en) Treatment of filaggrin (flg) related diseases by modulation of flg expression and activity
UA98629C2 (en) Compounds and methods for kinase modulation
UA107667C2 (en) Medical compounds stimulating activity of pyruvate kinase m2, compositions on their basis and use in the treatment of cancer
EP3311818A3 (en) Inhibitors of bruton's tyrosine kinase for the treatment of solid tumors
BRPI0813311A2 (en) COMPOUND, METHODS FOR MODULATING THE ACTIVITY OF A PROTEIN KINASE AND FOR TREATING CANCER IN AN INDIVIDUAL AND PHARMACEUTICAL COMPOSITION.
UA109878C2 (en) Isoquinolinone derivatives, pharmaceutical composition based on them (variants), and method of treating diseases (variants)
WO2014035140A3 (en) Compounds and compositions for modulating histone methyltransferase activity
MX2008006076A (en) Methods, compositions, and kits for the treatment of medical conditions.
BR112018007026A2 (en) compound, gaba-at activity modulation method, dopamine level modulation method, substance dependence treatment method, ornithine aminotransferase activity modulation method, ornithine aminotransferase activity reduction method expressed by a human hepatocellular carcinoma and method for treating psychological and neurological disorders
EP4295912A3 (en) Compounds and methods for kinase modulation, and indications therefor
WO2012040499A3 (en) Metabolic inhibitors
TN2011000176A1 (en) Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral or non-oral antidiabetic drug
WO2007117344A3 (en) Differentiating and/or identifying tissue regions innervated by targeted nerves
WO2008086025A3 (en) Treatment of respiratory chain disorders using compounds having erythropoietin or thrombopoietin activity
GB2473575A (en) Treatment and diagnosis of behavioural disorders
UY33276A (en) AMINO-OXAZINES AND AMINO-DIHYDROTIAZINE COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE
EA201370008A1 (en) TREATMENT OF COGNITIVE DISTURBANCES
WO2010034015A3 (en) Modulating the alternative complement pathway
WO2012009402A3 (en) Treatment of discs large homolog (dlg) related diseases by inhibition of natural antisense transcript to dlg
EP3712264A8 (en) Cystathionine beta-synthase enzyme for treatment of homocystinuria
WO2009015369A3 (en) Isophthalamide derivatives inhibiting beta-secretase activity
WO2011097522A3 (en) Combination methods for treatment of disease
MY155340A (en) Use of cathepsin c
MX2009009693A (en) Methods of activating irs-1 and akt.

Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)