JP2020534788A5 - - Google Patents
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- JP2020534788A5 JP2020534788A5 JP2019562303A JP2019562303A JP2020534788A5 JP 2020534788 A5 JP2020534788 A5 JP 2020534788A5 JP 2019562303 A JP2019562303 A JP 2019562303A JP 2019562303 A JP2019562303 A JP 2019562303A JP 2020534788 A5 JP2020534788 A5 JP 2020534788A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762551133P | 2017-08-28 | 2017-08-28 | |
| US62/551,133 | 2017-08-28 | ||
| PCT/US2018/047561 WO2019046069A1 (en) | 2017-08-28 | 2018-08-22 | ADENO-ASSOCIATED VIRUS CAPSID VARIANTS AND METHODS OF USE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020534788A JP2020534788A (ja) | 2020-12-03 |
| JP2020534788A5 true JP2020534788A5 (https=) | 2021-09-30 |
Family
ID=65525930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019562303A Withdrawn JP2020534788A (ja) | 2017-08-28 | 2018-08-22 | アデノ随伴ウイルスカプシド変異体及びその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11680249B2 (https=) |
| EP (1) | EP3676373A4 (https=) |
| JP (1) | JP2020534788A (https=) |
| KR (1) | KR20200039617A (https=) |
| CN (1) | CN110709511A (https=) |
| AU (1) | AU2018324477A1 (https=) |
| BR (1) | BR112020003571A2 (https=) |
| CA (1) | CA3059995A1 (https=) |
| MX (1) | MX2020001997A (https=) |
| WO (1) | WO2019046069A1 (https=) |
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| HRP20171334T1 (hr) | 2011-04-22 | 2017-11-17 | The Regents Of The University Of California | Virioni adeno-povezanog virusa s kapsid varijantom i postupci njihove upotrebe |
| US11136557B2 (en) | 2013-05-31 | 2021-10-05 | The Regents Of The University Of California | Adeno-associated virus variants and methods of use thereof |
| KR102537394B1 (ko) | 2014-03-17 | 2023-05-30 | 애드베룸 바이오테크놀로지스, 인코포레이티드 | 원추세포에서 증강된 유전자 발현을 위한 조성물 및 방법 |
| WO2015191508A1 (en) | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Chimeric capsids |
| EP3827812B1 (en) | 2016-07-29 | 2025-10-29 | The Regents of the University of California | Adeno-associated virus virions with variant capsid and methods of use thereof |
| CA3040179A1 (en) | 2016-10-19 | 2018-04-26 | Adverum Biotechnologies, Inc. | Modified aav capsids and uses thereof |
| WO2019006182A1 (en) * | 2017-06-30 | 2019-01-03 | The Regents Of The University Of California | VIRIONS OF ADENO-ASSOCIATED VIRUSES OF CAPSID VARIANTS AND METHODS OF USE THEREOF |
| JP7221275B2 (ja) | 2017-08-03 | 2023-02-13 | ボイジャー セラピューティクス インコーポレイテッド | Ａａｖを送達するための組成物および方法 |
| JP2020534788A (ja) | 2017-08-28 | 2020-12-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | アデノ随伴ウイルスカプシド変異体及びその使用方法 |
| US20200263199A1 (en) | 2017-09-29 | 2020-08-20 | Voyager Therapeutics, Inc. | Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery |
| US12054724B2 (en) | 2018-04-10 | 2024-08-06 | President And Fellows Of Harvard College | AAV vectors encoding clarin-1 or GJB2 and uses thereof |
| WO2020068990A1 (en) | 2018-09-26 | 2020-04-02 | California Institute Of Technology | Adeno-associated virus compositions for targeted gene therapy |
| US12281321B2 (en) | 2018-09-28 | 2025-04-22 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
| MX2021011701A (es) * | 2019-03-28 | 2021-12-10 | Massachusetts Gen Hospital | Vectores adenoasociados fabricados por ingenieria (aav) para expresion transgenica. |
| TW202102526A (zh) * | 2019-04-04 | 2021-01-16 | 美商銳進科斯生物股份有限公司 | 重組腺相關病毒及其用途 |
| AU2020271108A1 (en) * | 2019-04-11 | 2021-11-11 | California Institute Of Technology | Virus compositions with enhanced specificity in the brain |
| CN114072514A (zh) * | 2019-05-14 | 2022-02-18 | 杜克大学 | 用于治疗atp酶介导的疾病的组合物和方法 |
| IL297391A (en) | 2020-04-20 | 2022-12-01 | Tenaya Therapeutics Inc | An adeno-associated virus with an engineered capsid |
| CN116390934A (zh) * | 2020-05-26 | 2023-07-04 | 塑造治疗公司 | 功能性aav衣壳的高通量工程化 |
| JP2023528801A (ja) | 2020-05-29 | 2023-07-06 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | バリアントキャプシドを有するアデノ随伴ウイルスビリオン及びその使用方法 |
| US12129287B2 (en) | 2020-09-14 | 2024-10-29 | President And Fellows Of Harvard College | Recombinant adeno associated virus encoding clarin-1 and uses thereof |
| CN112194706B (zh) * | 2020-09-30 | 2022-03-08 | 广州派真生物技术有限公司 | 腺相关病毒突变体及其应用 |
| WO2022079082A1 (en) | 2020-10-15 | 2022-04-21 | F. Hoffmann-La Roche Ag | Nucleic acid constructs for simultaneous gene activation |
| CN113025658B (zh) * | 2021-03-10 | 2022-04-22 | 华侨大学 | 一种神经干细胞特异性基因的递送载体及其应用 |
| CN113121651B (zh) * | 2021-04-19 | 2023-11-17 | 信念医药科技(上海)有限公司 | 低中和抗体腺相关病毒衣壳蛋白 |
| US20240342311A1 (en) * | 2021-07-30 | 2024-10-17 | University Of Florida Research Foundation, Incorporated | Engineering aav vectors with improved cns targeting |
| CN114057840B (zh) * | 2021-10-14 | 2022-09-20 | 和元生物技术（上海）股份有限公司 | 包含变异的aav9衣壳蛋白的重组腺相关病毒颗粒 |
| CN119095866A (zh) * | 2022-02-22 | 2024-12-06 | 北卡罗来纳大学查佩尔希尔分校 | 嵌合神经向性aav衣壳 |
| CN119894920A (zh) * | 2022-07-22 | 2025-04-25 | 上海天泽云泰生物医药有限公司 | 用于靶向神经系统的新型aav衣壳及其用途 |
| CN116789738B (zh) * | 2022-12-08 | 2023-12-19 | 广州派真生物技术有限公司 | 腺相关病毒突变体及其应用 |
| CN117012275A (zh) * | 2023-08-11 | 2023-11-07 | 瑞诺元(苏州)生物科技有限公司 | 一种腺相关病毒测序数据的分析方法及系统 |
| WO2025147741A1 (en) * | 2024-01-11 | 2025-07-17 | Children's Medical Research Institute | Aav capsids and vectors for transduction of cells |
| KR20260014488A (ko) * | 2024-07-22 | 2026-01-30 | 한국생명공학연구원 | 변이체 캡시드를 포함하는 아데노-연관 바이러스 및 이의 용도 |
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2018
- 2018-08-22 JP JP2019562303A patent/JP2020534788A/ja not_active Withdrawn
- 2018-08-22 MX MX2020001997A patent/MX2020001997A/es unknown
- 2018-08-22 AU AU2018324477A patent/AU2018324477A1/en not_active Abandoned
- 2018-08-22 KR KR1020197035110A patent/KR20200039617A/ko not_active Withdrawn
- 2018-08-22 CN CN201880035665.2A patent/CN110709511A/zh active Pending
- 2018-08-22 WO PCT/US2018/047561 patent/WO2019046069A1/en not_active Ceased
- 2018-08-22 CA CA3059995A patent/CA3059995A1/en active Pending
- 2018-08-22 EP EP18850221.5A patent/EP3676373A4/en not_active Withdrawn
- 2018-08-22 US US16/500,706 patent/US11680249B2/en active Active
- 2018-08-22 BR BR112020003571-8A patent/BR112020003571A2/pt not_active IP Right Cessation
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