CN110709511A - 腺相关病毒衣壳变体及其使用方法 - Google Patents

腺相关病毒衣壳变体及其使用方法 Download PDF

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CN110709511A
CN110709511A CN201880035665.2A CN201880035665A CN110709511A CN 110709511 A CN110709511 A CN 110709511A CN 201880035665 A CN201880035665 A CN 201880035665A CN 110709511 A CN110709511 A CN 110709511A
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aav
amino acids
virion
fold
raav
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D·V·谢弗
D·S·奥贾拉
P·A·罗梅罗
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University of California San Diego UCSD
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University of California San Diego UCSD
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CN201880035665.2A 2017-08-28 2018-08-22 腺相关病毒衣壳变体及其使用方法 Pending CN110709511A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762551133P 2017-08-28 2017-08-28
US62/551,133 2017-08-28
PCT/US2018/047561 WO2019046069A1 (en) 2017-08-28 2018-08-22 ADENO-ASSOCIATED VIRUS CAPSID VARIANTS AND METHODS OF USE

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US (1) US11680249B2 (https=)
EP (1) EP3676373A4 (https=)
JP (1) JP2020534788A (https=)
KR (1) KR20200039617A (https=)
CN (1) CN110709511A (https=)
AU (1) AU2018324477A1 (https=)
BR (1) BR112020003571A2 (https=)
CA (1) CA3059995A1 (https=)
MX (1) MX2020001997A (https=)
WO (1) WO2019046069A1 (https=)

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CN113025658A (zh) * 2021-03-10 2021-06-25 华侨大学 一种神经干细胞特异性基因的递送载体及其应用
CN113121651A (zh) * 2021-04-19 2021-07-16 信念医药科技(上海)有限公司 新型低中和抗体腺相关病毒衣壳蛋白
CN113754727A (zh) * 2020-09-30 2021-12-07 广州派真生物技术有限公司 腺相关病毒突变体及其应用
CN116249772A (zh) * 2020-05-29 2023-06-09 加利福尼亚大学董事会 具有变体衣壳的腺相关病毒病毒体及其使用方法
CN116621935A (zh) * 2022-12-08 2023-08-22 广州派真生物技术有限公司 腺相关病毒突变体及其应用

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CN116390934A (zh) * 2020-05-26 2023-07-04 塑造治疗公司 功能性aav衣壳的高通量工程化
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US20240342311A1 (en) * 2021-07-30 2024-10-17 University Of Florida Research Foundation, Incorporated Engineering aav vectors with improved cns targeting
CN114057840B (zh) * 2021-10-14 2022-09-20 和元生物技术（上海）股份有限公司 包含变异的aav9衣壳蛋白的重组腺相关病毒颗粒
CN119095866A (zh) * 2022-02-22 2024-12-06 北卡罗来纳大学查佩尔希尔分校 嵌合神经向性aav衣壳
CN119894920A (zh) * 2022-07-22 2025-04-25 上海天泽云泰生物医药有限公司 用于靶向神经系统的新型aav衣壳及其用途
CN117012275A (zh) * 2023-08-11 2023-11-07 瑞诺元(苏州)生物科技有限公司 一种腺相关病毒测序数据的分析方法及系统
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