JPWO2022053630A5 - - Google Patents
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- Publication number
- JPWO2022053630A5 JPWO2022053630A5 JP2023515813A JP2023515813A JPWO2022053630A5 JP WO2022053630 A5 JPWO2022053630 A5 JP WO2022053630A5 JP 2023515813 A JP2023515813 A JP 2023515813A JP 2023515813 A JP2023515813 A JP 2023515813A JP WO2022053630 A5 JPWO2022053630 A5 JP WO2022053630A5
- Authority
- JP
- Japan
- Prior art keywords
- capsid protein
- sequence
- gene
- aav capsid
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20306005 | 2020-09-10 | ||
| EP20306005.8 | 2020-09-10 | ||
| PCT/EP2021/074964 WO2022053630A1 (en) | 2020-09-10 | 2021-09-10 | Peptide-modified aav capsid |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023544683A JP2023544683A (ja) | 2023-10-25 |
| JP2023544683A5 JP2023544683A5 (https=) | 2024-09-19 |
| JPWO2022053630A5 true JPWO2022053630A5 (https=) | 2024-09-19 |
| JP7834725B2 JP7834725B2 (ja) | 2026-03-24 |
Family
ID=72717827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023515813A Active JP7834725B2 (ja) | 2020-09-10 | 2021-09-10 | ペプチド改変されたａａｖカプシド |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240209030A1 (https=) |
| EP (2) | EP4211231B1 (https=) |
| JP (1) | JP7834725B2 (https=) |
| CN (1) | CN116096431A (https=) |
| CA (1) | CA3193128A1 (https=) |
| DK (1) | DK4211231T3 (https=) |
| ES (1) | ES2984259T3 (https=) |
| FI (1) | FI4211231T3 (https=) |
| PL (1) | PL4211231T3 (https=) |
| PT (1) | PT4211231T (https=) |
| WO (1) | WO2022053630A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL297391A (en) | 2020-04-20 | 2022-12-01 | Tenaya Therapeutics Inc | An adeno-associated virus with an engineered capsid |
| EP4314295A1 (en) | 2021-03-26 | 2024-02-07 | The Board Of Regents Of The University Of Texas System | Nucleotide editing to reframe dmd transcripts by base editing and prime editing |
| CN117897492A (zh) | 2021-08-04 | 2024-04-16 | 吉尼松公司 | 用于肌肉和cns中的基因表达的杂合启动子 |
| US20250249052A1 (en) * | 2022-04-07 | 2025-08-07 | Kate Therapeutics, Inc. | Compositions and methods for muscle disorders |
| CN116925192B (zh) * | 2022-04-12 | 2025-04-29 | 合肥星眸生物科技有限公司 | 一种融合型腺相关病毒及其应用 |
| JP2025524363A (ja) | 2022-06-09 | 2025-07-30 | ジェネトン | 糖原病ｉｉｉの処置のためのｎ末端短縮型ｇｄｅ |
| EP4707399A2 (en) | 2022-06-10 | 2026-03-11 | Généthon | Peptide-modified aav capsid with enhanced muscle transduction efficiency |
| US20260053923A1 (en) | 2022-10-07 | 2026-02-26 | Genethon | Immunotherapy of Skeletal Myopathies Using ANTI-FAP CAR-T Cells |
| EP4609882A1 (en) * | 2022-10-12 | 2025-09-03 | CPC Corporation | Gene introduction method, gene therapy method, and tissue regeneration method |
| TW202502803A (zh) | 2023-03-10 | 2025-01-16 | 美商戴諾治療公司 | 衣殼多肽及其使用方法 |
| EP4677073A1 (en) | 2023-03-10 | 2026-01-14 | Genethon | Induction of immune tolerance by aav vector comprising the combination of a liver detargeted capsid and a tandem liver-muscle specific promoter |
| CN121420060A (zh) | 2023-06-29 | 2026-01-27 | 吉尼松公司 | 用于治疗糖原贮积病iii的n-端截短的糖原脱支酶 |
| WO2025048709A1 (en) * | 2023-08-25 | 2025-03-06 | Agency For Science, Technology And Research | Composition and methods for identification of novel aav variants for differentiated gene delivery to cardiomyoctes and/or skeletal myofibers |
| WO2025133247A1 (en) | 2023-12-21 | 2025-06-26 | Genethon | Methods for aav vector re-administration |
| KR102933125B1 (ko) * | 2024-02-01 | 2026-03-04 | 주식회사 글루진테라퓨틱스 | 평활근 세포 특이적 유전자 전달이 가능한 아데노연관바이러스 벡터 |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| WO2026017727A1 (en) | 2024-07-16 | 2026-01-22 | Genethon | Alternative barcoding method to assess transduction efficiency of aav vectors |
| WO2026064428A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026064444A1 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1222673A1 (zh) * | 2013-07-12 | 2017-07-07 | The Children's Hospital Of Philadelphia | Aav载体和用於抗aav(腺相关病毒)中和抗体的检测 |
| PE20190401A1 (es) * | 2016-07-26 | 2019-03-13 | Biomarin Pharm Inc | Novedosas proteinas de la capside del virus adenoasociado |
| EP3775173A1 (en) | 2018-04-05 | 2021-02-17 | Genethon | Hybrid recombinant adeno-associated virus serotype between aav9 and aavrh74 with reduced liver tropism |
| AU2019258830B2 (en) | 2018-04-27 | 2025-12-18 | Universität Heidelberg | Modified AAV capsid polypeptides for treatment of muscular diseases |
-
2021
- 2021-09-10 PL PL21777271.4T patent/PL4211231T3/pl unknown
- 2021-09-10 EP EP21777271.4A patent/EP4211231B1/en active Active
- 2021-09-10 DK DK21777271.4T patent/DK4211231T3/da active
- 2021-09-10 CN CN202180055064.XA patent/CN116096431A/zh active Pending
- 2021-09-10 JP JP2023515813A patent/JP7834725B2/ja active Active
- 2021-09-10 ES ES21777271T patent/ES2984259T3/es active Active
- 2021-09-10 US US18/024,103 patent/US20240209030A1/en active Pending
- 2021-09-10 EP EP24183857.2A patent/EP4421179A3/en not_active Withdrawn
- 2021-09-10 PT PT217772714T patent/PT4211231T/pt unknown
- 2021-09-10 CA CA3193128A patent/CA3193128A1/en active Pending
- 2021-09-10 WO PCT/EP2021/074964 patent/WO2022053630A1/en not_active Ceased
- 2021-09-10 FI FIEP21777271.4T patent/FI4211231T3/fi active
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