JP2020534788A5 - - Google Patents
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- JP2020534788A5 JP2020534788A5 JP2019562303A JP2019562303A JP2020534788A5 JP 2020534788 A5 JP2020534788 A5 JP 2020534788A5 JP 2019562303 A JP2019562303 A JP 2019562303A JP 2019562303 A JP2019562303 A JP 2019562303A JP 2020534788 A5 JP2020534788 A5 JP 2020534788A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762551133P | 2017-08-28 | 2017-08-28 | |
| US62/551,133 | 2017-08-28 | ||
| PCT/US2018/047561 WO2019046069A1 (en) | 2017-08-28 | 2018-08-22 | ADENO-ASSOCIATED VIRUS CAPSID VARIANTS AND METHODS OF USE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020534788A JP2020534788A (ja) | 2020-12-03 |
| JP2020534788A5 true JP2020534788A5 (OSRAM) | 2021-09-30 |
Family
ID=65525930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019562303A Withdrawn JP2020534788A (ja) | 2017-08-28 | 2018-08-22 | アデノ随伴ウイルスカプシド変異体及びその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11680249B2 (OSRAM) |
| EP (1) | EP3676373A4 (OSRAM) |
| JP (1) | JP2020534788A (OSRAM) |
| KR (1) | KR20200039617A (OSRAM) |
| CN (1) | CN110709511A (OSRAM) |
| AU (1) | AU2018324477A1 (OSRAM) |
| BR (1) | BR112020003571A2 (OSRAM) |
| CA (1) | CA3059995A1 (OSRAM) |
| MX (1) | MX2020001997A (OSRAM) |
| WO (1) | WO2019046069A1 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107012171B (zh) | 2011-04-22 | 2021-07-13 | 加利福尼亚大学董事会 | 具有变异衣壳的腺相关病毒病毒体及其使用方法 |
| CN105247044B (zh) | 2013-05-31 | 2021-05-07 | 加利福尼亚大学董事会 | 腺相关病毒变体及其使用方法 |
| EP3800191B1 (en) | 2014-03-17 | 2025-08-20 | Adverum Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
| US10577627B2 (en) | 2014-06-09 | 2020-03-03 | Voyager Therapeutics, Inc. | Chimeric capsids |
| EP4700118A3 (en) | 2016-07-29 | 2026-04-22 | The Regents of the University of California | Adeno-associated virus virions with varint capsid and methods of use thereof |
| CA3040179A1 (en) | 2016-10-19 | 2018-04-26 | Adverum Biotechnologies, Inc. | Modified aav capsids and uses thereof |
| EP3645052A4 (en) | 2017-06-30 | 2021-07-28 | Regents of the University of California | ADENO-ASSOCIATED VIRUS VIRIONS WITH ASSOCIATED CAPSIDE VARIANTS AND METHODS OF USE |
| TWI832036B (zh) | 2017-08-03 | 2024-02-11 | 美商航海家醫療公司 | 用於aav之遞送之組合物及方法 |
| KR20200039617A (ko) | 2017-08-28 | 2020-04-16 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 아데노-연관 바이러스 캡시드 변이체 및 이의 사용 방법 |
| MX2020003042A (es) | 2017-09-29 | 2020-11-18 | Voyager Therapeutics Inc | Rescate del fenotipo neurológico central y periférico de la ataxia de friedreich mediante administración intravenosa. |
| WO2019200016A1 (en) | 2018-04-10 | 2019-10-17 | President And Fellows Of Harvard College | Aav vectors encoding clarin-1 or gjb2 and uses thereof |
| SG11202103102WA (en) | 2018-09-26 | 2021-04-29 | California Inst Of Techn | Adeno-associated virus compositions for targeted gene therapy |
| CN113383010B (zh) | 2018-09-28 | 2025-09-09 | 沃雅戈治疗公司 | 具有经工程化改造的启动子的共济蛋白表达构建体及其使用方法 |
| AU2020248116B2 (en) * | 2019-03-28 | 2025-12-04 | President And Fellows Of Harvard College | Engineered adeno-associated (AAV) vectors for transgene expression |
| TW202102526A (zh) * | 2019-04-04 | 2021-01-16 | 美商銳進科斯生物股份有限公司 | 重組腺相關病毒及其用途 |
| KR20220007056A (ko) * | 2019-04-11 | 2022-01-18 | 캘리포니아 인스티튜트 오브 테크놀로지 | 뇌에서 증진된 특이성을 갖는 바이러스 조성물 |
| JP2022531809A (ja) * | 2019-05-14 | 2022-07-11 | デューク ユニバーシティ | ＡＴＰａｓｅ媒介性疾患の処置のための組成物および方法 |
| KR20230004719A (ko) | 2020-04-20 | 2023-01-06 | 테나야 테라퓨틱스, 인코포레이티드 | 조작된 캡시드를 갖는 아데노-연관 바이러스 |
| JP2023529315A (ja) * | 2020-05-26 | 2023-07-10 | シェイプ セラピューティクス インコーポレイテッド | 機能的ａａｖカプシドのハイスループット工学操作 |
| CA3179597A1 (en) | 2020-05-29 | 2021-12-02 | John G. Flannery | Adeno-associated virus virions with variant capsids and methods of use thereof |
| US12129287B2 (en) | 2020-09-14 | 2024-10-29 | President And Fellows Of Harvard College | Recombinant adeno associated virus encoding clarin-1 and uses thereof |
| CN113754727B (zh) * | 2020-09-30 | 2022-07-12 | 广州派真生物技术有限公司 | 腺相关病毒突变体及其应用 |
| EP4229204A1 (en) | 2020-10-15 | 2023-08-23 | F. Hoffmann-La Roche AG | Nucleic acid constructs for simultaneous gene activation |
| CN113025658B (zh) * | 2021-03-10 | 2022-04-22 | 华侨大学 | 一种神经干细胞特异性基因的递送载体及其应用 |
| CN113121651B (zh) * | 2021-04-19 | 2023-11-17 | 信念医药科技(上海)有限公司 | 低中和抗体腺相关病毒衣壳蛋白 |
| US20240342311A1 (en) * | 2021-07-30 | 2024-10-17 | University Of Florida Research Foundation, Incorporated | Engineering aav vectors with improved cns targeting |
| CN114057840B (zh) * | 2021-10-14 | 2022-09-20 | 和元生物技术（上海）股份有限公司 | 包含变异的aav9衣壳蛋白的重组腺相关病毒颗粒 |
| EP4482850A1 (en) * | 2022-02-22 | 2025-01-01 | The University of North Carolina at Chapel Hill | Chimeric neurotropic aav capsids |
| CN119894920A (zh) * | 2022-07-22 | 2025-04-25 | 上海天泽云泰生物医药有限公司 | 用于靶向神经系统的新型aav衣壳及其用途 |
| CN116789738B (zh) * | 2022-12-08 | 2023-12-19 | 广州派真生物技术有限公司 | 腺相关病毒突变体及其应用 |
| CN117012275A (zh) * | 2023-08-11 | 2023-11-07 | 瑞诺元(苏州)生物科技有限公司 | 一种腺相关病毒测序数据的分析方法及系统 |
| WO2025147741A1 (en) * | 2024-01-11 | 2025-07-17 | Children's Medical Research Institute | Aav capsids and vectors for transduction of cells |
| WO2026024048A1 (ko) * | 2024-07-22 | 2026-01-29 | 한국생명공학연구원 | 변이체 캡시드를 포함하는 아데노-연관 바이러스 및 이의 용도 |
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| US6551795B1 (en) | 1998-02-18 | 2003-04-22 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics |
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| US6943153B1 (en) | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
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-
2018
- 2018-08-22 KR KR1020197035110A patent/KR20200039617A/ko not_active Withdrawn
- 2018-08-22 EP EP18850221.5A patent/EP3676373A4/en not_active Withdrawn
- 2018-08-22 MX MX2020001997A patent/MX2020001997A/es unknown
- 2018-08-22 JP JP2019562303A patent/JP2020534788A/ja not_active Withdrawn
- 2018-08-22 AU AU2018324477A patent/AU2018324477A1/en not_active Abandoned
- 2018-08-22 WO PCT/US2018/047561 patent/WO2019046069A1/en not_active Ceased
- 2018-08-22 BR BR112020003571-8A patent/BR112020003571A2/pt not_active IP Right Cessation
- 2018-08-22 CA CA3059995A patent/CA3059995A1/en active Pending
- 2018-08-22 CN CN201880035665.2A patent/CN110709511A/zh active Pending
- 2018-08-22 US US16/500,706 patent/US11680249B2/en active Active
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