JP2023544683A5 - - Google Patents
Info
- Publication number
- JP2023544683A5 JP2023544683A5 JP2023515813A JP2023515813A JP2023544683A5 JP 2023544683 A5 JP2023544683 A5 JP 2023544683A5 JP 2023515813 A JP2023515813 A JP 2023515813A JP 2023515813 A JP2023515813 A JP 2023515813A JP 2023544683 A5 JP2023544683 A5 JP 2023544683A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- capsid protein
- muscle
- aav capsid
- terminus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20306005 | 2020-09-10 | ||
| EP20306005.8 | 2020-09-10 | ||
| PCT/EP2021/074964 WO2022053630A1 (en) | 2020-09-10 | 2021-09-10 | Peptide-modified aav capsid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023544683A JP2023544683A (ja) | 2023-10-25 |
| JP2023544683A5 true JP2023544683A5 (OSRAM) | 2024-09-19 |
| JP7834725B2 JP7834725B2 (ja) | 2026-03-24 |
Family
ID=72717827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023515813A Active JP7834725B2 (ja) | 2020-09-10 | 2021-09-10 | ペプチド改変されたａａｖカプシド |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240209030A1 (OSRAM) |
| EP (2) | EP4211231B1 (OSRAM) |
| JP (1) | JP7834725B2 (OSRAM) |
| CN (1) | CN116096431A (OSRAM) |
| CA (1) | CA3193128A1 (OSRAM) |
| DK (1) | DK4211231T3 (OSRAM) |
| ES (1) | ES2984259T3 (OSRAM) |
| FI (1) | FI4211231T3 (OSRAM) |
| PL (1) | PL4211231T3 (OSRAM) |
| PT (1) | PT4211231T (OSRAM) |
| WO (1) | WO2022053630A1 (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230004719A (ko) | 2020-04-20 | 2023-01-06 | 테나야 테라퓨틱스, 인코포레이티드 | 조작된 캡시드를 갖는 아데노-연관 바이러스 |
| US20240165271A1 (en) | 2021-03-26 | 2024-05-23 | The Board Of Regents Of The University Of Texas System | Nucleotide editing to reframe dmd transcripts by base editing and prime editing |
| CN117897492A (zh) | 2021-08-04 | 2024-04-16 | 吉尼松公司 | 用于肌肉和cns中的基因表达的杂合启动子 |
| EP4504952A4 (en) * | 2022-04-07 | 2026-04-08 | Kate Therapeutics Inc | COMPOSITIONS AND METHODS FOR MUSCULAR DISORDERS |
| CN120590489A (zh) * | 2022-04-12 | 2025-09-05 | 合肥星眸生物科技有限公司 | 一种融合型腺相关病毒及其应用 |
| CA3252764A1 (en) | 2022-06-09 | 2023-12-14 | Institut National de la Santé et de la Recherche Médicale | GDE truncated at the N-terminal level for the treatment of type III glycogen storage disease |
| PL4536686T3 (pl) | 2022-06-10 | 2026-03-23 | Genethon | Kapsyd aav zmodyfikowany peptydem o zwiększonej skuteczności transdukcji mięśniowej |
| CN120112308A (zh) | 2022-10-07 | 2025-06-06 | 吉尼松公司 | 使用抗fap car-t细胞免疫治疗骨骼肌病 |
| CN120035601A (zh) * | 2022-10-12 | 2025-05-23 | Ｃｐｃ株式会社 | 基因导入法、基因治疗法及组织再生法 |
| WO2024191778A1 (en) | 2023-03-10 | 2024-09-19 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2024188913A1 (en) | 2023-03-10 | 2024-09-19 | Genethon | Induction of immune tolerance by aav vector comprising the combination of a liver detargeted capsid and a tandem liver-muscle specific promoter |
| CN121420060A (zh) | 2023-06-29 | 2026-01-27 | 吉尼松公司 | 用于治疗糖原贮积病iii的n-端截短的糖原脱支酶 |
| CN121941776A (zh) * | 2023-08-25 | 2026-04-28 | 新加坡科技研究局 | 用于鉴定向心肌和/或骨骼肌纤维进行差异化基因递送的新型aav变体的组合物和方法 |
| WO2025133247A1 (en) | 2023-12-21 | 2025-06-26 | Genethon | Methods for aav vector re-administration |
| WO2025165162A1 (ko) * | 2024-02-01 | 2025-08-07 | 주식회사 글루진테라퓨틱스 | 평활근 세포 특이적 유전자 전달이 가능한 아데노연관바이러스 벡터 |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| WO2026017727A1 (en) | 2024-07-16 | 2026-01-22 | Genethon | Alternative barcoding method to assess transduction efficiency of aav vectors |
| CN119751595B (zh) * | 2024-07-16 | 2025-09-09 | 广州派真生物技术有限公司 | 腺相关病毒突变体及其应用 |
| WO2026064428A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026064444A1 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014287005C1 (en) * | 2013-07-12 | 2021-06-03 | The Children's Hospital Of Philadelphia | AAV vector and assay for anti-AAV (adeno-associated virus) neutralizing antibodies |
| AU2017301600B2 (en) * | 2016-07-26 | 2022-08-04 | Biomarin Pharmaceutical Inc. | Novel adeno-associated virus capsid proteins |
| CN112004925B (zh) | 2018-04-05 | 2024-09-27 | 吉尼松公司 | 具有降低的肝向性的AAV9和AAVrh74的杂合重组腺相关病毒血清型 |
| CA3097375A1 (en) | 2018-04-27 | 2019-10-31 | Universitat Heidelberg | Modified aav capsid polypeptides for treatment of muscular diseases |
-
2021
- 2021-09-10 WO PCT/EP2021/074964 patent/WO2022053630A1/en not_active Ceased
- 2021-09-10 ES ES21777271T patent/ES2984259T3/es active Active
- 2021-09-10 EP EP21777271.4A patent/EP4211231B1/en active Active
- 2021-09-10 PL PL21777271.4T patent/PL4211231T3/pl unknown
- 2021-09-10 CA CA3193128A patent/CA3193128A1/en active Pending
- 2021-09-10 US US18/024,103 patent/US20240209030A1/en active Pending
- 2021-09-10 CN CN202180055064.XA patent/CN116096431A/zh active Pending
- 2021-09-10 PT PT217772714T patent/PT4211231T/pt unknown
- 2021-09-10 FI FIEP21777271.4T patent/FI4211231T3/fi active
- 2021-09-10 DK DK21777271.4T patent/DK4211231T3/da active
- 2021-09-10 JP JP2023515813A patent/JP7834725B2/ja active Active
- 2021-09-10 EP EP24183857.2A patent/EP4421179A3/en not_active Withdrawn
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