JP2020528933A5 - - Google Patents
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- JP2020528933A5 JP2020528933A5 JP2020526718A JP2020526718A JP2020528933A5 JP 2020528933 A5 JP2020528933 A5 JP 2020528933A5 JP 2020526718 A JP2020526718 A JP 2020526718A JP 2020526718 A JP2020526718 A JP 2020526718A JP 2020528933 A5 JP2020528933 A5 JP 2020528933A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- compound
- formula
- phenyl
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762538675P | 2017-07-29 | 2017-07-29 | |
| US62/538,675 | 2017-07-29 | ||
| PCT/IL2018/050836 WO2019026065A2 (en) | 2017-07-29 | 2018-07-26 | NOVEL BRAF INHIBITORS AND THEIR USE FOR THE TREATMENT OF SKIN REACTIONS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020528933A JP2020528933A (ja) | 2020-10-01 |
| JP2020528933A5 true JP2020528933A5 (enExample) | 2021-03-04 |
| JP6912667B2 JP6912667B2 (ja) | 2021-08-04 |
Family
ID=65233550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526718A Active JP6912667B2 (ja) | 2017-07-29 | 2018-07-26 | 新規なｂｒａｆ阻害剤および皮膚反応を治療するためのその使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10927112B2 (enExample) |
| EP (1) | EP3661515B1 (enExample) |
| JP (1) | JP6912667B2 (enExample) |
| KR (1) | KR102328351B1 (enExample) |
| CN (1) | CN111132680B (enExample) |
| AU (1) | AU2018311538B2 (enExample) |
| CA (1) | CA3070542C (enExample) |
| DK (1) | DK3661515T3 (enExample) |
| ES (1) | ES2908602T3 (enExample) |
| HR (1) | HRP20220609T1 (enExample) |
| IL (1) | IL272312B (enExample) |
| MX (1) | MX383386B (enExample) |
| SI (1) | SI3661515T1 (enExample) |
| WO (1) | WO2019026065A2 (enExample) |
| ZA (1) | ZA202000354B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11458139B2 (en) * | 2017-08-08 | 2022-10-04 | Memorial Sloan Kettering Cancer Center | Use of BRAF inhibitors for treating cutaneous reactions caused by treatment with a MEK inhibitor |
| MX2021009535A (es) | 2019-02-12 | 2022-10-10 | Lutris Pharma Ltd | Uso de composiciones tópicas de inhibidores de braf para el tratamiento de la dermatitis por radiación. |
| WO2022136912A1 (en) * | 2020-12-24 | 2022-06-30 | Lutris Pharma Ltd. | Topical braf inhibitor compositions for treatment of egfr downstream effectors - induced reactions |
| WO2023275620A2 (en) * | 2021-07-02 | 2023-01-05 | Lutris Pharma Ltd. | Use of isoquinoline-1,5-diamines for wound healing |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5753612A (en) | 1992-10-27 | 1998-05-19 | Yissum Research Development Co. Of The Hebrew University Of Jerusalem | Pharmaceutical composition and method for inhibiting hair growth by administration of activin or activin agonists |
| US7989461B2 (en) | 2005-12-23 | 2011-08-02 | Amgen Inc. | Substituted quinazolinamine compounds for the treatment of cancer |
| US8557830B2 (en) * | 2007-06-07 | 2013-10-15 | Amgen Inc. | RAF kinase modulators and methods of use |
| TWI611053B (zh) | 2012-02-27 | 2018-01-11 | 曾宇鳳 | 為先導藥物最適化之以結構為基礎的片段遷越及合成可行性之改良 |
| KR20140011780A (ko) | 2012-07-19 | 2014-01-29 | 한미약품 주식회사 | 단백질 키나아제 저해활성을 갖는 이소퀴놀린-5-카복스아미드 유도체 |
| RU2015149937A (ru) * | 2013-05-30 | 2017-07-06 | Плексксикон Инк. | Соединения для модулирования киназы и показания к их применению |
| CN106535900A (zh) * | 2014-05-06 | 2017-03-22 | 加利福尼亚大学董事会 | 使用braf抑制剂的伤口愈合 |
| CN109069511A (zh) | 2016-03-10 | 2018-12-21 | 鲁特里斯制药有限公司 | Braf抑制剂用于治疗皮肤反应的用途 |
-
2018
- 2018-07-26 SI SI201830670T patent/SI3661515T1/sl unknown
- 2018-07-26 KR KR1020207005707A patent/KR102328351B1/ko active Active
- 2018-07-26 JP JP2020526718A patent/JP6912667B2/ja active Active
- 2018-07-26 EP EP18841422.1A patent/EP3661515B1/en active Active
- 2018-07-26 CN CN201880060593.7A patent/CN111132680B/zh active Active
- 2018-07-26 WO PCT/IL2018/050836 patent/WO2019026065A2/en not_active Ceased
- 2018-07-26 AU AU2018311538A patent/AU2018311538B2/en active Active
- 2018-07-26 MX MX2020000939A patent/MX383386B/es unknown
- 2018-07-26 DK DK18841422.1T patent/DK3661515T3/da active
- 2018-07-26 CA CA3070542A patent/CA3070542C/en active Active
- 2018-07-26 ES ES18841422T patent/ES2908602T3/es active Active
- 2018-07-26 HR HRP20220609TT patent/HRP20220609T1/hr unknown
-
2019
- 2019-06-13 US US16/440,601 patent/US10927112B2/en active Active
-
2020
- 2020-01-17 ZA ZA2020/00354A patent/ZA202000354B/en unknown
- 2020-01-28 IL IL272312A patent/IL272312B/en active IP Right Grant
- 2020-11-20 US US17/100,181 patent/US11339163B2/en active Active
-
2022
- 2022-05-17 US US17/746,446 patent/US20220274988A1/en not_active Abandoned
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