JP2020528449A5 - - Google Patents

Download PDF

Info

Publication number
JP2020528449A5
JP2020528449A5 JP2020519008A JP2020519008A JP2020528449A5 JP 2020528449 A5 JP2020528449 A5 JP 2020528449A5 JP 2020519008 A JP2020519008 A JP 2020519008A JP 2020519008 A JP2020519008 A JP 2020519008A JP 2020528449 A5 JP2020528449 A5 JP 2020528449A5
Authority
JP
Japan
Prior art keywords
composition
gastrin
cancer
tumor
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020519008A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020528449A (ja
JP7469225B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/037737 external-priority patent/WO2018232230A1/en
Publication of JP2020528449A publication Critical patent/JP2020528449A/ja
Publication of JP2020528449A5 publication Critical patent/JP2020528449A5/ja
Priority to JP2023216520A priority Critical patent/JP2024038041A/ja
Application granted granted Critical
Publication of JP7469225B2 publication Critical patent/JP7469225B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020519008A 2017-06-15 2018-06-15 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法 Active JP7469225B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023216520A JP2024038041A (ja) 2017-06-15 2023-12-22 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762520267P 2017-06-15 2017-06-15
US62/520,267 2017-06-15
PCT/US2018/037737 WO2018232230A1 (en) 2017-06-15 2018-06-15 Compositions and methods for inducing humoral and cellular immunities against tumors and cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023216520A Division JP2024038041A (ja) 2017-06-15 2023-12-22 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法

Publications (3)

Publication Number Publication Date
JP2020528449A JP2020528449A (ja) 2020-09-24
JP2020528449A5 true JP2020528449A5 (https=) 2021-04-30
JP7469225B2 JP7469225B2 (ja) 2024-04-16

Family

ID=64659743

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020519008A Active JP7469225B2 (ja) 2017-06-15 2018-06-15 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法
JP2023216520A Pending JP2024038041A (ja) 2017-06-15 2023-12-22 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023216520A Pending JP2024038041A (ja) 2017-06-15 2023-12-22 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法

Country Status (9)

Country Link
US (3) US11583576B2 (https=)
EP (1) EP3624841A4 (https=)
JP (2) JP7469225B2 (https=)
KR (1) KR102772810B1 (https=)
CN (1) CN111050789A (https=)
AU (2) AU2018283284B2 (https=)
CA (1) CA3066756A1 (https=)
IL (1) IL271427B2 (https=)
WO (1) WO2018232230A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer
WO2018232230A1 (en) 2017-06-15 2018-12-20 Cancer Advances Inc. Compositions and methods for inducing humoral and cellular immunities against tumors and cancer
US11725056B2 (en) * 2017-10-03 2023-08-15 Cedars-Sinai Medical Center Methods for targeting the immune checkpoint PD1 pathway for treating pulmonary fibrosis
DK3720879T3 (da) * 2017-12-05 2022-06-20 Progastrine Et Cancers S A R L Kombinationsterapi mellem anti-progastrin-antistof og immunterapi til behandling af cancer
EP4225346A4 (en) * 2020-11-06 2025-01-01 Cancer Advances, Inc., Compositions and methods for enhancing t cell penetration of tumors and cancers
JP2024504924A (ja) * 2021-01-13 2024-02-02 キャンサー アドヴァンシーズ インク. 腫瘍及びがんを予防するための組成物及び方法

Family Cites Families (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3391141A (en) 1966-07-07 1968-07-02 Bristol Myers Co Synthetic cephalosporins
US5006334A (en) 1973-05-07 1991-04-09 The Ohio State University Antigenic modification of polypeptides
US4691006A (en) 1983-03-04 1987-09-01 Ohio State University Antigenic modification of polypeptides
US4201770A (en) 1973-05-07 1980-05-06 The Ohio State University Antigenic modification of polypeptides
US4762913A (en) 1973-05-07 1988-08-09 The Ohio State University Antigenic modification of polypeptides
US4526716A (en) 1981-11-20 1985-07-02 The Ohio State University Antigenic modification of polypeptides
US4384995A (en) 1980-01-16 1983-05-24 The Ohio State University Antigenic modification of polypeptides
US4069313A (en) 1974-11-19 1978-01-17 Merck & Co., Inc. Water-in-oil adjuvant composition
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
SU1414392A1 (ru) 1982-12-29 1988-08-07 Всесоюзный кардиологический научный центр АМН СССР Противо звенное средство
US4925922A (en) 1983-02-22 1990-05-15 Xoma Corporation Potentiation of cytotoxic conjugates
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4828991A (en) 1984-01-31 1989-05-09 Akzo N.V. Tumor specific monoclonal antibodies
US4894443A (en) 1984-02-08 1990-01-16 Cetus Corporation Toxin conjugates
CA1289077C (en) 1984-08-13 1991-09-17 Harry H. Leveen Treatment of cancer with phlorizin and its derivatives
FR2575164B1 (fr) 1984-12-20 1987-03-20 Sanofi Sa Esters de tri- et tetrapeptides inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant
IT1179894B (it) 1984-12-27 1987-09-16 Rotta Research Lab Proglumide e composizioni farmaceutiche che la contengono per l impiego nella terapia di affezioni neoplastiche
US4803170A (en) 1985-05-09 1989-02-07 Ultra Diagnostics Corporation Competitive immunoassay method, device and test kit
US4713366A (en) 1985-12-04 1987-12-15 The Ohio State University Research Foundation Antigenic modification of polypeptides
IT1204430B (it) 1986-01-10 1989-03-01 Alfio Bertolini Composizioni farmaceutiche comprendenti peptidi del gruppo colecistochinina-cerulina per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoria
CA1341281C (en) 1986-07-09 2001-08-07 Hubert J.P. Schoemaker Immunotherapy of tumor with monoclonal antibody against the 17-1a antigen
US5344919A (en) 1987-02-19 1994-09-06 The Scripps Research Institute Integrin from human epithelial cells
US4971792A (en) 1987-03-27 1990-11-20 The Wistar Institute Monoclonal antibodies against glycolipid antigens
US4923819A (en) 1987-03-27 1990-05-08 Chimerix Corporation Time-resolved fluorescence immunoassay
WO1989005156A1 (en) 1987-12-09 1989-06-15 The General Hospital Corporation Carcinoma-associated antigens, and antibodies which recognize these antigens
US5035988A (en) 1988-05-12 1991-07-30 Fuji Photo Film Co., Ltd. Silver halide photographic material containing a yellow coupler and a phosphorus compound and color image forming method
US5162504A (en) 1988-06-03 1992-11-10 Cytogen Corporation Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients
JPH0249596A (ja) 1988-08-09 1990-02-19 Masamichi Ueda ヒト前立腺上皮細胞の表面に特異的に反応するモノクローナル抗体
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5759791A (en) 1989-01-17 1998-06-02 The Johns Hopkins University Cancer related antigen
US5023077A (en) 1989-01-24 1991-06-11 Aphton Corporation Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease
ES2063912T3 (es) * 1989-01-24 1995-01-16 Aphton Corp Composiciones inmunogenicas frente a peptidos de gastrina.
US5120829A (en) 1989-03-20 1992-06-09 La Jolla Cancer Research Foundation Hydrophobic attachment site for adhesion peptides
US4997950A (en) 1989-04-20 1991-03-05 Richard Finbar Murphy Novel C-terminal gastrin antagonists
US6020145A (en) 1989-06-30 2000-02-01 Bristol-Myers Squibb Company Methods for determining the presence of carcinoma using the antigen binding region of monoclonal antibody BR96
US5770576A (en) 1989-08-30 1998-06-23 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
US5110911A (en) 1989-11-02 1992-05-05 Biomira, Inc. Human tumor-associated thomsen-friedenreich antigen
US5164299A (en) 1990-03-20 1992-11-17 E. I. Du Pont De Nemours And Company Use of a mixture of conjugated and unconjugated solid phase binding reagent to enhance the performance of assays
US5932412A (en) 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
US5733790A (en) 1991-01-15 1998-03-31 The Salk Institute For Biological Studies CRF binding protein antibodies and assays using same
US5668117A (en) 1991-02-22 1997-09-16 Shapiro; Howard K. Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
GB9115364D0 (en) 1991-07-16 1991-08-28 Wellcome Found Antibody
US5319073A (en) 1992-02-07 1994-06-07 The United States Of America, As Represented By The Department Of Health & Human Services Method of purifying cholecystokinin receptor protein
US5256542A (en) 1992-03-09 1993-10-26 Tanox Biosystems, Inc. Selecting low frequency antigen-specific single B lymphocytes with correction for background noise
US5580563A (en) 1992-05-01 1996-12-03 Tam; James P. Multiple antigen peptide system having adjuvant properties, vaccines prepared therefrom and methods of use thereof
DE69317282D1 (de) 1992-05-08 1998-04-09 Receptagen Corp Anti-Rezeptor Antikörper gegen den Vitamin B12/transcobalamin II Rezeptor
US5639613A (en) 1992-05-13 1997-06-17 Board Of Regents, University Of Texas System Methods for cancer diagnosis and prognosis
DE69333623T3 (de) 1992-06-23 2014-05-15 Mount Sinai School Of Medicine Klonierung und expression von gonadotropinreleasing hormon
US5736146A (en) 1992-07-30 1998-04-07 Yeda Research And Development Co. Ltd. Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them
JP3439490B2 (ja) 1992-09-28 2003-08-25 株式会社林原生物化学研究所 蛋白質とその蛋白質をコードするdna並びにその蛋白質の製造方法
JP3628029B2 (ja) 1992-09-30 2005-03-09 塩野義製薬株式会社 ガストリン拮抗剤の新用途
ATE373486T1 (de) 1992-09-30 2007-10-15 Univ Ohio State Res Found Impfstoffe zur behandlung von kolonkrebs
US5879898A (en) 1992-11-20 1999-03-09 Isis Innovation Limited Antibodies specific for peptide corresponding to CD44 exon 6, and use of these antibodies for diagnosis of tumors
US5683695A (en) 1993-02-10 1997-11-04 United Biomedical, Inc. Production of recombinant proteins containing multiple antigenic determinants linked by flexible hinge domains
US5759551A (en) 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
CA2168584C (en) 1993-08-09 2008-10-14 Edward Baral A method for sensitization of cancer cells for killer cell mediated lysis
US5601990A (en) 1994-09-13 1997-02-11 Thomas Jefferson University Methods of diagnosing colorectal tumors and metastasis thereof
US5468494A (en) 1993-11-12 1995-11-21 Aphton Corp. Immunogenic compositions against human gastrin 17
US5750119A (en) 1994-01-13 1998-05-12 Mount Sinai School Of Medicine Of The City University Of New York Immunotherapeutic stress protein-peptide complexes against cancer
AU1681095A (en) 1994-01-14 1995-08-01 Matthias Rath Hydrophilic signal oligopeptides and methods of therapeutic use
US7300918B2 (en) 1994-01-14 2007-11-27 Matthias Rath Method of producing vaccines from protein signal oligopeptides
US5688506A (en) 1994-01-27 1997-11-18 Aphton Corp. Immunogens against gonadotropin releasing hormone
WO1995021380A1 (en) 1994-02-02 1995-08-10 Ludwig Institute For Cancer Research Assay for screening of receptor antagonists
US5767242A (en) 1994-04-20 1998-06-16 Boehringer Ingelheim Int'l Gmbh Isolated dimeric fibroblast activation protein alpha, and uses thereof
US5869058A (en) 1994-05-25 1999-02-09 Yeda Research And Development Co. Ltd. Peptides used as carriers in immunogenic constructs suitable for development of synthetic vaccines
CA2195753C (en) 1994-07-25 2008-12-16 Ursula-Henrike Wienhues Determination of a specific immunoglobulin using multiple antigens
JP3853384B2 (ja) 1994-09-09 2006-12-06 株式会社三菱化学ヤトロン 抗サイモシンα1モノクローナル抗体産生ハイブリドーマ
US5789000A (en) 1994-11-14 1998-08-04 Bionumerik Pharmaceuticals, Inc. Sterile aqueous parenteral formulations of cis-diammine dichloro platinum
FI97304C (fi) 1994-11-16 1996-11-25 Locus Genex Oy Menetelmä mahasyövän riskin seulonnaksi
US5723718A (en) 1994-12-20 1998-03-03 St. Joseph's Hospital And Medical Center Induction of immune tolerance to tumor cells
US5955504A (en) 1995-03-13 1999-09-21 Loma Linda University Medical Center Colorectal chemoprotective composition and method of preventing colorectal cancer
US7078493B1 (en) 1995-03-15 2006-07-18 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor-like genes
EP0824596A1 (en) 1995-05-12 1998-02-25 Schering Corporation Surface plasmon resonance based enzymatic assay
US6359114B1 (en) 1995-06-07 2002-03-19 Aphton Corp. System for method for the modification and purification of proteins
US5811097A (en) 1995-07-25 1998-09-22 The Regents Of The University Of California Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
US5712369A (en) 1995-08-24 1998-01-27 Ludwig Institute For Cancer Research Isolated protein which binds to A33 antibody, and peptides corresponding to portions of the protein
DE69602756T2 (de) 1995-08-18 2000-02-10 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Rockville Funktionelle rolle von adrenomedullin(am) und dem gen-verwandten produkt(pamp) in der menschlichen pathologie und physiologie
MA24512A1 (fr) 1996-01-17 1998-12-31 Univ Vermont And State Agrienl Procede pour la preparation d'agents anticoagulants utiles dans le traitement de la thrombose
ATE505202T1 (de) 1996-02-08 2011-04-15 Cancer Advances Inc Immunologische methoden zur behandlung von gastrointestinalem krebs
US5786213A (en) 1996-04-18 1998-07-28 Board Of Regents, The University Of Texas System Inhibition of endogenous gastrin expression for treatment of colorectal cancer
CA2257108A1 (en) 1996-06-07 1997-12-11 Takeda Chemical Industries, Ltd. Novel peptides and production and use thereof
IL118626A0 (en) 1996-06-11 1996-10-16 Xtl Biopharmaceuticals Limited Anti HBV antibody
JPH1026621A (ja) 1996-07-12 1998-01-27 Dai Ichi Pure Chem Co Ltd イムノアッセイ法
UA76934C2 (en) 1996-10-04 2006-10-16 Chugai Pharmaceutical Co Ltd Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
US6472506B1 (en) 1997-01-21 2002-10-29 Aventis Pasteur S.A. Polysaccharide-peptide-conjugates
WO1998035707A1 (en) 1997-02-18 1998-08-20 Thomas Jefferson University Compositions that bind to pancreatic cancer cells and methods of using the same
US20040001842A1 (en) 1997-05-12 2004-01-01 Dov Michaeli Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors
ES2227833T3 (es) 1997-05-12 2005-04-01 Aphton Corporation Composiciones inmunogenicas para el receptor cck-b/gastrina y metodos para el tratamiento de tumores.
AUPO982097A0 (en) 1997-10-15 1997-11-06 University Of Melbourne, The Methods and compositions for use therein
US6565813B1 (en) 1998-02-04 2003-05-20 Merck & Co., Inc. Virtual wells for use in high throughput screening assays
EP1579863A3 (en) 1998-05-15 2008-03-19 Receptor Biologix, Inc. Combination therapy with anti-gastrin G17 antibodies for the treatment of tumors
KR100699574B1 (ko) 1998-05-15 2007-03-23 리셉터 바이오로직스 인크 종양 치료를 위한 조합 치료
AU4080399A (en) 1998-05-15 1999-12-06 Aphton Corporation Prevention and treatment of hypergastrinemia
US20030068326A1 (en) 1998-05-15 2003-04-10 Aphton Corporation Method for the treatment of gastroesophageal reflux disease
CA2331834A1 (en) 1998-06-18 1999-12-23 Michal Y. Chowers Pharmaceutical compositions for the treatment of helicobacter pylori-associated disorders
DE19956568A1 (de) 1999-01-30 2000-08-17 Roland Kreutzer Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
AU768027B2 (en) 1999-02-24 2003-11-27 Uab Research Foundation, The Taxane derivatives for targeted therapy of cancer
FI118653B (fi) 1999-04-30 2008-01-31 Biohit Oyj Menetelmä peptisen haavan riskin määrittämiseksi
FR2797689B1 (fr) 1999-08-16 2003-06-27 Pasteur Sanofi Diagnostics Utilisation de composes synthetiques pour des immunodosages
TR200200472T2 (tr) 1999-08-27 2002-06-21 Genentech, Inc. Anti-Erb B2 antikorları ile tedavi için dozajlar
WO2001034192A2 (en) 1999-11-08 2001-05-17 Aphton Corporation Improved method of immunization
US20020058040A1 (en) 1999-12-23 2002-05-16 Stephen Grimes Stable immunogenic composition for frozen storage
WO2001077685A2 (en) 2000-04-10 2001-10-18 The General Hospital Corporation Diagnosis and treatment of gastrointestinal disease
US20030138860A1 (en) 2000-06-14 2003-07-24 Robertson John Forsyth Russell Cancer detection methods and reagents
US20030232399A1 (en) 2000-06-14 2003-12-18 Robertson John Forsyth Russell Cancer detection methods and reagents
US6780969B2 (en) 2000-12-22 2004-08-24 United Biomedical, Inc. Synthetic peptide composition as immunogens for prevention of urinary tract infection
CN1312181C (zh) 2001-02-12 2007-04-25 米德列斯公司 抗Fcα受体(CD89)的人单克隆抗体
JP2005508838A (ja) 2001-03-23 2005-04-07 アフトン コーポレーション 膵癌の組合せ治療
US20090191232A1 (en) 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
JP2004536835A (ja) 2001-07-09 2004-12-09 アフトン コーポレーション 肝臓、肺および食道の癌性ならびに前癌性状態の治療および防止
BRPI0214168B8 (pt) 2001-11-14 2021-05-25 Centocor Inc anticorpos anti-il-6, moléculas de ácido nucleico codificando os mesmos, vetores compreendendo as referidas moléculas, composições e formulações compreendendo os referidos anticorpos, bem como métodos de produção dos mesmos
EP1837031B1 (en) 2002-06-07 2009-10-14 Waratah Pharmaceuticals, Inc. Compositions and methods for treating diabetes
US20050169979A1 (en) 2002-07-03 2005-08-04 Dov Michaeli Liposomal vaccine
US20040208920A1 (en) 2002-07-03 2004-10-21 Dov Michaeli Liposomal vaccine
US20040247661A1 (en) 2002-07-03 2004-12-09 Dov Michaeli Liposomal vaccine
ES2350687T3 (es) 2002-07-03 2011-01-26 Ono Pharmaceutical Co., Ltd. Composiciones de inmunopotenciación.
FI119571B (fi) 2002-09-06 2008-12-31 Biohit Oyj Menetelmä esofagiitin tai Barrettin ruokatorven riskin osoittamiseksi yksilöllä
US20030049698A1 (en) 2002-10-08 2003-03-13 Wang Timothy C. Diagnosis and treatment of gastrointestinal disease
US7438907B2 (en) 2002-11-15 2008-10-21 Genmab A/S Human monoclonal antibodies against CD25
JP4689597B2 (ja) 2003-03-28 2011-05-25 レセプター バイオロジックス インク. ガストリンホルモン免疫アッセイ
WO2004089976A1 (en) 2003-04-08 2004-10-21 The University Of Melbourne Method of treatment
EP1730193A2 (en) 2004-03-29 2006-12-13 Receptor Biologix, Inc. Monoclonal antibodies to gastrin hormone
CN1997669A (zh) 2004-03-29 2007-07-11 受体生物技术公司 抗胃泌素激素单克隆抗体
WO2006008649A1 (en) 2004-07-15 2006-01-26 Aphton Corporation Anti-sense polynucleotide therapy for gastrin-promoted tumors
AU2005270917A1 (en) 2004-08-11 2006-02-16 Cancer Advances, Inc. Gastrin-specific interfering RNA
US7662926B2 (en) 2004-09-02 2010-02-16 Genentech, Inc. Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor
KR101333168B1 (ko) 2004-09-22 2013-11-28 리셉터 바이오로직스 인크 프로가스트린에 대한 모노클로날 항체
EP1971363A1 (en) 2005-12-02 2008-09-24 Waratah Pharmaceuticals, Inc. Combination treatments with gastrin agonists for diabetes and related diseases
CN100558747C (zh) * 2006-04-06 2009-11-11 海南天源康泽医药科技有限公司 以白喉毒素突变体crm197为载体的免疫原及其制备方法与应用
US7854932B2 (en) 2006-12-19 2010-12-21 The Board Of Regents Of The University Of Texas System Immunogenic compositions comprising progastrin and uses thereof
EP3375791A1 (en) 2009-09-30 2018-09-19 Memorial Sloan Kettering Cancer Center Combination immunotherapy for the treatment of cancer
US8900588B2 (en) * 2010-01-08 2014-12-02 Les Laboratories Servier Methods for treating breast cancer
GB201121571D0 (en) * 2011-12-15 2012-01-25 Astrimmune Ltd Compounds and uses thereof
ES2665780T3 (es) 2013-05-21 2018-04-27 Tyg Oncology Ltd. Composición inmunogénica de péptido de gastrina
CN104232576B (zh) 2013-06-14 2018-07-17 加思葆(北京)医药科技有限公司 蛋白-细胞偶联物、其制备方法和用途
WO2015069571A1 (en) * 2013-11-05 2015-05-14 Bavarian Nordic, Inc. Combination therapy for treating cancer with a poxvirus expressing a tumor antigen and an antagonist and/or agonist of an immune checkpoint inhibitor
MX2017015618A (es) * 2015-06-03 2018-08-15 Boston Biomedical Inc Composiciones que comprenden un inhibidor de la autorrenovación y diferenciación de células madre cancerosas y un agente inmunoterapéutico para su uso en el tratamiento del cáncer.
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer
WO2018232230A1 (en) 2017-06-15 2018-12-20 Cancer Advances Inc. Compositions and methods for inducing humoral and cellular immunities against tumors and cancer
JP2024504924A (ja) 2021-01-13 2024-02-02 キャンサー アドヴァンシーズ インク. 腫瘍及びがんを予防するための組成物及び方法

Similar Documents

Publication Publication Date Title
JP2020528449A5 (https=)
JP2022068348A (ja) がんに対する組合せ療法
KR102721494B1 (ko) 고갈성 항 cd4 단일클론항체를 포함하는 항암 t 세포치료제 보조용 조성물 및 이의 용도
CA2687368C (en) Vaccine for the prevention of breast cancer relapse
JP6698541B2 (ja) 細胞性の細胞傷害性免疫応答を誘導または延長する方法における使用のための医薬
EP2839291B1 (en) Multivalent breast cancer vaccine
JP4970035B2 (ja) invivoにおける樹状細胞の標的化
US20250312428A1 (en) Heterologous Prime Boost Vaccine
JP2022553192A (ja) 癌ワクチン
JP7822620B2 (ja) 免疫療法のエンハンサーとして有用なil-10/fc融合タンパク質
Franks et al. New anticancer immunotherapies
US20200000899A1 (en) Pharmaceutical composition for use in the treatment of cancer
Natarajan et al. Novel immunotherapeutic agents and small molecule antagonists of signalling kinases for the treatment of metastatic melanoma
WO2011139738A2 (en) Therapies using zanolimumab to enhance the immune response
Schütz et al. MHC‐Ig induces memory T cell formation in vivo and inhibits tumour growth
AU2017440798C1 (en) Improved treatment of cancer
KR20090099011A (ko) 암의 치료를 위한 수술, 화학요법 또는 방사선요법과 조합된 면역요법에서 mage a3-단백질 d 융합 항원의 용도
CA2990893C (fr) Peptides immunogenes de preprocalcitonine
US20250066420A1 (en) Pd-l1 inhibitory peptide for cancer immunotherapy
US20240415828A1 (en) Tlr7 agonist and combinations for cancer treatment
US20220008512A1 (en) Anti-cancer monotherapy using sa-4-1bbl
Boghossian et al. Tumour vaccines, monoclonals, proteins or whole cell therapies