JP2020523354A - Ｔｎｂｃを処置するための化合物 - Google Patents

Ｔｎｂｃを処置するための化合物 Download PDF

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Publication number
JP2020523354A
JP2020523354A JP2019568645A JP2019568645A JP2020523354A JP 2020523354 A JP2020523354 A JP 2020523354A JP 2019568645 A JP2019568645 A JP 2019568645A JP 2019568645 A JP2019568645 A JP 2019568645A JP 2020523354 A JP2020523354 A JP 2020523354A
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JP
Japan
Prior art keywords
tinostamustine
pharmaceutically acceptable
acceptable salt
tnbc
treatment
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2019568645A
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English (en)
Japanese (ja)
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JP2020523354A5 (https=
Inventor
トーマス・ヨーク・メーリング
Original Assignee
ユーロ−セルティーク エス．エイ．
ユーロ−セルティーク エス．エイ．
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Application filed by ユーロ−セルティーク エス．エイ．, ユーロ−セルティーク エス．エイ． filed Critical ユーロ−セルティーク エス．エイ．
Publication of JP2020523354A publication Critical patent/JP2020523354A/ja
Publication of JP2020523354A5 publication Critical patent/JP2020523354A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019568645A 2017-06-13 2018-06-13 Ｔｎｂｃを処置するための化合物 Pending JP2020523354A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1709406.1 2017-06-13
GBGB1709406.1A GB201709406D0 (en) 2017-06-13 2017-06-13 Compounds for treating TNBC
PCT/EP2018/065662 WO2018229130A1 (en) 2017-06-13 2018-06-13 Compounds for treating tnbc

Publications (2)

Publication Number Publication Date
JP2020523354A true JP2020523354A (ja) 2020-08-06
JP2020523354A5 JP2020523354A5 (https=) 2021-07-29

Family

ID=59358315

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019568645A Pending JP2020523354A (ja) 2017-06-13 2018-06-13 Ｔｎｂｃを処置するための化合物

Country Status (14)

Country Link
US (4) US11413276B2 (https=)
EP (1) EP3638228B1 (https=)
JP (1) JP2020523354A (https=)
KR (1) KR20200014789A (https=)
AR (1) AR112103A1 (https=)
AU (1) AU2018285819A1 (https=)
BR (1) BR112019026474A2 (https=)
CA (1) CA3067058A1 (https=)
ES (1) ES2959952T3 (https=)
GB (1) GB201709406D0 (https=)
IL (1) IL271018A (https=)
MX (1) MX390945B (https=)
TW (1) TW201919615A (https=)
WO (1) WO2018229130A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021505583A (ja) * 2017-12-05 2021-02-18 エンジェクス ファーマシューティカル インコーポレイテッド Ｐｍｒｔ５阻害剤としての複素環式化合物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409485D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
AU2016426574B2 (en) 2016-10-11 2023-07-13 Euro-Celtique S.A. Hodgkin lymphoma therapy
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
GB201709405D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
CN113365624A (zh) 2018-12-18 2021-09-07 萌蒂制药国际有限公司 用于治疗淋巴瘤或t-细胞恶性疾病的化合物

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021505583A (ja) * 2017-12-05 2021-02-18 エンジェクス ファーマシューティカル インコーポレイテッド Ｐｍｒｔ５阻害剤としての複素環式化合物

Also Published As

Publication number Publication date
US12303492B2 (en) 2025-05-20
GB201709406D0 (en) 2017-07-26
BR112019026474A2 (pt) 2020-07-14
US20230080216A1 (en) 2023-03-16
US11786509B2 (en) 2023-10-17
US11413276B2 (en) 2022-08-16
US20250275945A1 (en) 2025-09-04
EP3638228B1 (en) 2023-08-23
US20200230109A1 (en) 2020-07-23
WO2018229130A1 (en) 2018-12-20
EP3638228C0 (en) 2023-08-23
MX390945B (es) 2025-03-21
MX2019015211A (es) 2022-03-23
KR20200014789A (ko) 2020-02-11
IL271018A (en) 2020-01-30
AR112103A1 (es) 2019-09-18
ES2959952T3 (es) 2024-02-29
CA3067058A1 (en) 2018-12-20
AU2018285819A1 (en) 2019-12-19
US20240139155A1 (en) 2024-05-02
EP3638228A1 (en) 2020-04-22
TW201919615A (zh) 2019-06-01

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