AR112103A1 - Compuestos para el tratamiento de tnbc - Google Patents

Compuestos para el tratamiento de tnbc

Info

Publication number
AR112103A1
AR112103A1 ARP180101625A ARP180101625A AR112103A1 AR 112103 A1 AR112103 A1 AR 112103A1 AR P180101625 A ARP180101625 A AR P180101625A AR P180101625 A ARP180101625 A AR P180101625A AR 112103 A1 AR112103 A1 AR 112103A1
Authority
AR
Argentina
Prior art keywords
pharmaceutically acceptable
tnbc
treatment
compounds
tinostamustine
Prior art date
Application number
ARP180101625A
Other languages
English (en)
Inventor
Thomas Jorg Mehrling
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of AR112103A1 publication Critical patent/AR112103A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Tinostamustina o una sal farmacéuticamente aceptable de la misma para uso en el tratamiento del cáncer de mama negativo triple (TNBC). Reivindicación 17: Una combinación que contiene tinostamustina o una sal farmacéuticamente aceptable de la misma, y agente(s) adicional(es) seleccionado(s) de inhibidores de reparación de ADN o inhibidores de DDR. Reivindicación 19: Una composición farmacéutica que contiene un vehículo farmacéuticamente aceptable y una combinación de acuerdo con una cualquiera de las reivindicaciones 17 a 18.
ARP180101625A 2017-06-13 2018-06-13 Compuestos para el tratamiento de tnbc AR112103A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1709406.1A GB201709406D0 (en) 2017-06-13 2017-06-13 Compounds for treating TNBC

Publications (1)

Publication Number Publication Date
AR112103A1 true AR112103A1 (es) 2019-09-18

Family

ID=59358315

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180101625A AR112103A1 (es) 2017-06-13 2018-06-13 Compuestos para el tratamiento de tnbc

Country Status (14)

Country Link
US (3) US11413276B2 (es)
EP (1) EP3638228B1 (es)
JP (1) JP2020523354A (es)
KR (1) KR20200014789A (es)
AR (1) AR112103A1 (es)
AU (1) AU2018285819A1 (es)
BR (1) BR112019026474A2 (es)
CA (1) CA3067058A1 (es)
ES (1) ES2959952T3 (es)
GB (1) GB201709406D0 (es)
IL (1) IL271018A (es)
MX (1) MX2019015211A (es)
TW (1) TW201919615A (es)
WO (1) WO2018229130A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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GB201409485D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
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CA3040155C (en) 2016-10-11 2024-01-16 Euro-Celtique S.A. Compound for use in the treatment of hodgkin lymphoma
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
GB201709405D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
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Also Published As

Publication number Publication date
MX2019015211A (es) 2022-03-23
IL271018A (en) 2020-01-30
US20240139155A1 (en) 2024-05-02
EP3638228B1 (en) 2023-08-23
EP3638228A1 (en) 2020-04-22
EP3638228C0 (en) 2023-08-23
AU2018285819A1 (en) 2019-12-19
WO2018229130A1 (en) 2018-12-20
BR112019026474A2 (pt) 2020-07-14
US20230080216A1 (en) 2023-03-16
KR20200014789A (ko) 2020-02-11
JP2020523354A (ja) 2020-08-06
US11786509B2 (en) 2023-10-17
ES2959952T3 (es) 2024-02-29
US11413276B2 (en) 2022-08-16
US20200230109A1 (en) 2020-07-23
GB201709406D0 (en) 2017-07-26
CA3067058A1 (en) 2018-12-20
TW201919615A (zh) 2019-06-01

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