JP2020523354A - Ｔｎｂｃを処置するための化合物 - Google Patents

Ｔｎｂｃを処置するための化合物 Download PDF

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Publication number
JP2020523354A
JP2020523354A JP2019568645A JP2019568645A JP2020523354A JP 2020523354 A JP2020523354 A JP 2020523354A JP 2019568645 A JP2019568645 A JP 2019568645A JP 2019568645 A JP2019568645 A JP 2019568645A JP 2020523354 A JP2020523354 A JP 2020523354A
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JP
Japan
Prior art keywords
tinostamustine
pharmaceutically acceptable
acceptable salt
tnbc
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019568645A
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English (en)
Japanese (ja)
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JP2020523354A5 (enExample
Inventor
トーマス・ヨーク・メーリング
Original Assignee
ユーロ−セルティーク エス．エイ．
ユーロ−セルティーク エス．エイ．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by ユーロ−セルティーク エス．エイ．, ユーロ−セルティーク エス．エイ． filed Critical ユーロ−セルティーク エス．エイ．
Publication of JP2020523354A publication Critical patent/JP2020523354A/ja
Publication of JP2020523354A5 publication Critical patent/JP2020523354A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019568645A 2017-06-13 2018-06-13 Ｔｎｂｃを処置するための化合物 Pending JP2020523354A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1709406.1 2017-06-13
GBGB1709406.1A GB201709406D0 (en) 2017-06-13 2017-06-13 Compounds for treating TNBC
PCT/EP2018/065662 WO2018229130A1 (en) 2017-06-13 2018-06-13 Compounds for treating tnbc

Publications (2)

Publication Number Publication Date
JP2020523354A true JP2020523354A (ja) 2020-08-06
JP2020523354A5 JP2020523354A5 (enExample) 2021-07-29

Family

ID=59358315

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019568645A Pending JP2020523354A (ja) 2017-06-13 2018-06-13 Ｔｎｂｃを処置するための化合物

Country Status (14)

Country Link
US (4) US11413276B2 (enExample)
EP (1) EP3638228B1 (enExample)
JP (1) JP2020523354A (enExample)
KR (1) KR20200014789A (enExample)
AR (1) AR112103A1 (enExample)
AU (1) AU2018285819A1 (enExample)
BR (1) BR112019026474A2 (enExample)
CA (1) CA3067058A1 (enExample)
ES (1) ES2959952T3 (enExample)
GB (1) GB201709406D0 (enExample)
IL (1) IL271018A (enExample)
MX (1) MX390945B (enExample)
TW (1) TW201919615A (enExample)
WO (1) WO2018229130A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021505583A (ja) * 2017-12-05 2021-02-18 エンジェクス ファーマシューティカル インコーポレイテッド Ｐｍｒｔ５阻害剤としての複素環式化合物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409485D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
US11266631B2 (en) 2016-10-11 2022-03-08 Purdue Pharmaceutical Products L.P. Hodgkin lymphoma therapy
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
GB201709405D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
WO2020128912A1 (en) * 2018-12-18 2020-06-25 Mundipharma International Corporation Limited Compounds for treating lymphoma or a t-cell malignant disease

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021505583A (ja) * 2017-12-05 2021-02-18 エンジェクス ファーマシューティカル インコーポレイテッド Ｐｍｒｔ５阻害剤としての複素環式化合物

Also Published As

Publication number Publication date
EP3638228A1 (en) 2020-04-22
EP3638228C0 (en) 2023-08-23
ES2959952T3 (es) 2024-02-29
AR112103A1 (es) 2019-09-18
US11786509B2 (en) 2023-10-17
US11413276B2 (en) 2022-08-16
US20230080216A1 (en) 2023-03-16
US20240139155A1 (en) 2024-05-02
EP3638228B1 (en) 2023-08-23
KR20200014789A (ko) 2020-02-11
US20250275945A1 (en) 2025-09-04
US12303492B2 (en) 2025-05-20
AU2018285819A1 (en) 2019-12-19
WO2018229130A1 (en) 2018-12-20
IL271018A (en) 2020-01-30
CA3067058A1 (en) 2018-12-20
GB201709406D0 (en) 2017-07-26
MX2019015211A (es) 2022-03-23
MX390945B (es) 2025-03-21
TW201919615A (zh) 2019-06-01
US20200230109A1 (en) 2020-07-23
BR112019026474A2 (pt) 2020-07-14

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