JP2020519568A5 - - Google Patents
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- Publication number
- JP2020519568A5 JP2020519568A5 JP2019556888A JP2019556888A JP2020519568A5 JP 2020519568 A5 JP2020519568 A5 JP 2020519568A5 JP 2019556888 A JP2019556888 A JP 2019556888A JP 2019556888 A JP2019556888 A JP 2019556888A JP 2020519568 A5 JP2020519568 A5 JP 2020519568A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- alkyl
- formula
- compound represented
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 27
- 206010028980 Neoplasm Diseases 0.000 claims 14
- 125000000217 alkyl group Chemical group 0.000 claims 14
- 201000011510 cancer Diseases 0.000 claims 12
- 125000003545 alkoxy group Chemical group 0.000 claims 9
- 229910052794 bromium Inorganic materials 0.000 claims 9
- 229910052801 chlorine Inorganic materials 0.000 claims 7
- 229910052731 fluorine Inorganic materials 0.000 claims 7
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims 6
- 125000002252 acyl group Chemical group 0.000 claims 6
- 208000009956 adenocarcinoma Diseases 0.000 claims 6
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 5
- 206010006187 Breast cancer Diseases 0.000 claims 4
- 208000026310 Breast neoplasm Diseases 0.000 claims 4
- 206010060862 Prostate cancer Diseases 0.000 claims 4
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000003174 Brain Neoplasms Diseases 0.000 claims 2
- 206010008342 Cervix carcinoma Diseases 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 2
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 208000003445 Mouth Neoplasms Diseases 0.000 claims 2
- 208000002231 Muscle Neoplasms Diseases 0.000 claims 2
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 2
- 208000000821 Parathyroid Neoplasms Diseases 0.000 claims 2
- 208000002471 Penile Neoplasms Diseases 0.000 claims 2
- 206010034299 Penile cancer Diseases 0.000 claims 2
- 208000009565 Pharyngeal Neoplasms Diseases 0.000 claims 2
- 206010034811 Pharyngeal cancer Diseases 0.000 claims 2
- 208000015634 Rectal Neoplasms Diseases 0.000 claims 2
- 206010038389 Renal cancer Diseases 0.000 claims 2
- 208000016624 Retinal neoplasm Diseases 0.000 claims 2
- 208000000453 Skin Neoplasms Diseases 0.000 claims 2
- 208000000277 Splenic Neoplasms Diseases 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- 208000024313 Testicular Neoplasms Diseases 0.000 claims 2
- 206010057644 Testis cancer Diseases 0.000 claims 2
- 208000024770 Thyroid neoplasm Diseases 0.000 claims 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 2
- 201000005188 adrenal gland cancer Diseases 0.000 claims 2
- 208000024447 adrenal gland neoplasm Diseases 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 210000000941 bile Anatomy 0.000 claims 2
- 201000006491 bone marrow cancer Diseases 0.000 claims 2
- 201000010881 cervical cancer Diseases 0.000 claims 2
- 208000029742 colonic neoplasm Diseases 0.000 claims 2
- 201000000787 conjunctival cancer Diseases 0.000 claims 2
- 201000004101 esophageal cancer Diseases 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 208000014829 head and neck neoplasm Diseases 0.000 claims 2
- 201000010235 heart cancer Diseases 0.000 claims 2
- 208000024348 heart neoplasm Diseases 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 201000010982 kidney cancer Diseases 0.000 claims 2
- 150000002596 lactones Chemical class 0.000 claims 2
- 208000012987 lip and oral cavity carcinoma Diseases 0.000 claims 2
- 201000007270 liver cancer Diseases 0.000 claims 2
- 208000014018 liver neoplasm Diseases 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 2
- 208000026045 malignant tumor of parathyroid gland Diseases 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 201000002077 muscle cancer Diseases 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 201000002528 pancreatic cancer Diseases 0.000 claims 2
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 2
- 206010038038 rectal cancer Diseases 0.000 claims 2
- 201000001275 rectum cancer Diseases 0.000 claims 2
- 201000008933 retinal cancer Diseases 0.000 claims 2
- 201000008407 sebaceous adenocarcinoma Diseases 0.000 claims 2
- 201000000849 skin cancer Diseases 0.000 claims 2
- 201000002471 spleen cancer Diseases 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 210000004243 sweat Anatomy 0.000 claims 2
- 201000003120 testicular cancer Diseases 0.000 claims 2
- 210000000115 thoracic cavity Anatomy 0.000 claims 2
- 201000002510 thyroid cancer Diseases 0.000 claims 2
- 206010044285 tracheal cancer Diseases 0.000 claims 2
- 206010061336 Pelvic neoplasm Diseases 0.000 claims 1
- 208000007913 Pituitary Neoplasms Diseases 0.000 claims 1
- 235000009754 Vitis X bourquina Nutrition 0.000 claims 1
- 235000012333 Vitis X labruscana Nutrition 0.000 claims 1
- 240000006365 Vitis vinifera Species 0.000 claims 1
- 235000014787 Vitis vinifera Nutrition 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 201000005787 hematologic cancer Diseases 0.000 claims 1
- 230000002489 hematologic effect Effects 0.000 claims 1
- 208000024200 hematopoietic and lymphoid system neoplasm Diseases 0.000 claims 1
- 210000002751 lymph Anatomy 0.000 claims 1
- 201000010453 lymph node cancer Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 201000002511 pituitary cancer Diseases 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 0 **c1c(*)c(*)c(C2=C**C=C2)c2*(*)c(*)c(*)*(*)c12 Chemical compound **c1c(*)c(*)c(C2=C**C=C2)c2*(*)c(*)c(*)*(*)c12 0.000 description 2
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201621035967 | 2017-04-20 | ||
| IN201621035967 | 2017-04-20 | ||
| IN201721045003 | 2017-12-14 | ||
| IN201721045003 | 2017-12-14 | ||
| PCT/IN2018/050237 WO2018193476A2 (en) | 2017-04-20 | 2018-04-19 | Anticancer compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020519568A JP2020519568A (ja) | 2020-07-02 |
| JP2020519568A5 true JP2020519568A5 (enExample) | 2021-05-27 |
| JP7198221B2 JP7198221B2 (ja) | 2022-12-28 |
Family
ID=62244517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019556888A Active JP7198221B2 (ja) | 2017-04-20 | 2018-04-19 | 抗癌化合物 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11084843B2 (enExample) |
| EP (1) | EP3612172B1 (enExample) |
| JP (1) | JP7198221B2 (enExample) |
| ES (1) | ES3030482T3 (enExample) |
| WO (1) | WO2018193476A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113365615A (zh) * | 2018-12-17 | 2021-09-07 | 戈达瓦里生物炼制有限责任公司 | 抑制不受调控细胞生长的化合物 |
| MX2022014109A (es) * | 2020-05-11 | 2023-02-22 | Godavari Biorefineries Ltd | Uso de compuestos para el tratamiento de infecciones virales. |
| US20250025441A1 (en) * | 2021-09-22 | 2025-01-23 | Godavari Biorefineries Limited | Pharmaceutical composition and a process to prepare the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101463055B (zh) * | 2009-01-15 | 2010-12-08 | 天津药物研究院 | 一类o-糖苷化合物、其制备方法和用途 |
| US20120029179A1 (en) | 2009-02-05 | 2012-02-02 | Godavari Biorefineries Ltd. | Process for the synthesis of cleistanthin |
| WO2012081038A2 (en) | 2010-12-17 | 2012-06-21 | Godavari Biorefineries Limited | Anticancer compounds and targeting cancer with the same |
| WO2012099247A1 (ja) * | 2011-01-21 | 2012-07-26 | 花王株式会社 | 美白剤 |
| WO2014097318A2 (en) | 2012-12-18 | 2014-06-26 | Godavari Biorefineries Limited | Agents for eliminating tumour-initiating cells |
| WO2015002038A1 (ja) * | 2013-07-01 | 2015-01-08 | 株式会社トクヤマ | 新規なフェニルナフトール誘導体 |
| CN103467463B (zh) * | 2013-09-18 | 2016-06-22 | 南开大学 | 一类木脂素类衍生物及其制备方法和用途 |
| WO2015153653A1 (en) | 2014-03-31 | 2015-10-08 | Ohio State Innovation Foundation | Arylnaphthalene lactone derivatives and methods of making and using thereof |
| WO2016025779A1 (en) | 2014-08-14 | 2016-02-18 | Rigel Pharmaceuticals, Inc. | Quinoline derivatives useful as ubiquitination inhibitors |
| CN104844614B (zh) * | 2015-03-31 | 2016-09-14 | 华东师范大学 | 奥托肉豆蔻脂素化合物及制备方法和用途 |
-
2018
- 2018-04-19 JP JP2019556888A patent/JP7198221B2/ja active Active
- 2018-04-19 ES ES18727059T patent/ES3030482T3/es active Active
- 2018-04-19 WO PCT/IN2018/050237 patent/WO2018193476A2/en not_active Ceased
- 2018-04-19 EP EP18727059.0A patent/EP3612172B1/en active Active
- 2018-04-19 US US16/336,460 patent/US11084843B2/en active Active
-
2021
- 2021-06-30 US US17/364,570 patent/US11680078B2/en active Active
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