JP2020515280A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020515280A5 JP2020515280A5 JP2019554692A JP2019554692A JP2020515280A5 JP 2020515280 A5 JP2020515280 A5 JP 2020515280A5 JP 2019554692 A JP2019554692 A JP 2019554692A JP 2019554692 A JP2019554692 A JP 2019554692A JP 2020515280 A5 JP2020515280 A5 JP 2020515280A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- amino acid
- nanostructure
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022167524A JP7541701B2 (ja) | 2017-04-04 | 2022-10-19 | パラミクソウイルスおよび／またはニューモウイルスのｆタンパク質を表示する自己アセンブリするタンパク質ナノ構造およびその使用 |
| JP2024132065A JP2024160321A (ja) | 2017-04-04 | 2024-08-08 | パラミクソウイルスおよび／またはニューモウイルスのｆタンパク質を表示する自己アセンブリするタンパク質ナノ構造およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762481331P | 2017-04-04 | 2017-04-04 | |
| US62/481,331 | 2017-04-04 | ||
| PCT/US2018/025880 WO2018187325A1 (en) | 2017-04-04 | 2018-04-03 | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus f proteins and their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022167524A Division JP7541701B2 (ja) | 2017-04-04 | 2022-10-19 | パラミクソウイルスおよび／またはニューモウイルスのｆタンパク質を表示する自己アセンブリするタンパク質ナノ構造およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020515280A JP2020515280A (ja) | 2020-05-28 |
| JP2020515280A5 true JP2020515280A5 (https=) | 2021-05-06 |
| JP7168938B2 JP7168938B2 (ja) | 2022-11-10 |
Family
ID=62116943
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019554692A Active JP7168938B2 (ja) | 2017-04-04 | 2018-04-03 | パラミクソウイルスおよび／またはニューモウイルスのｆタンパク質を表示する自己アセンブリするタンパク質ナノ構造およびその使用 |
| JP2022167524A Active JP7541701B2 (ja) | 2017-04-04 | 2022-10-19 | パラミクソウイルスおよび／またはニューモウイルスのｆタンパク質を表示する自己アセンブリするタンパク質ナノ構造およびその使用 |
| JP2024132065A Pending JP2024160321A (ja) | 2017-04-04 | 2024-08-08 | パラミクソウイルスおよび／またはニューモウイルスのｆタンパク質を表示する自己アセンブリするタンパク質ナノ構造およびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022167524A Active JP7541701B2 (ja) | 2017-04-04 | 2022-10-19 | パラミクソウイルスおよび／またはニューモウイルスのｆタンパク質を表示する自己アセンブリするタンパク質ナノ構造およびその使用 |
| JP2024132065A Pending JP2024160321A (ja) | 2017-04-04 | 2024-08-08 | パラミクソウイルスおよび／またはニューモウイルスのｆタンパク質を表示する自己アセンブリするタンパク質ナノ構造およびその使用 |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US11192926B2 (https=) |
| EP (2) | EP4559869A3 (https=) |
| JP (3) | JP7168938B2 (https=) |
| KR (2) | KR102774312B1 (https=) |
| CN (3) | CN115779077A (https=) |
| AU (3) | AU2018249533C1 (https=) |
| BR (1) | BR112019020661A2 (https=) |
| CA (1) | CA3058794A1 (https=) |
| DK (1) | DK3606942T3 (https=) |
| ES (1) | ES3040563T3 (https=) |
| FI (1) | FI3606942T3 (https=) |
| HR (1) | HRP20251060T1 (https=) |
| HU (1) | HUE073526T2 (https=) |
| IL (2) | IL322023A (https=) |
| LT (1) | LT3606942T (https=) |
| MX (2) | MX2019011869A (https=) |
| PH (1) | PH12019502276A1 (https=) |
| PL (1) | PL3606942T3 (https=) |
| PT (1) | PT3606942T (https=) |
| RS (1) | RS67190B1 (https=) |
| SG (1) | SG11201908999QA (https=) |
| SI (1) | SI3606942T1 (https=) |
| SM (1) | SMT202500317T1 (https=) |
| WO (1) | WO2018187325A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9630994B2 (en) * | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
| HUE073526T2 (hu) * | 2017-04-04 | 2026-01-28 | Univ Washington | Önmagát összeállító fehérje nanostruktúrák, amelyek paramyxovírus és/vagy pneumovírus F fehérjéket jelenítenek meg és azok használata |
| EP3746090A4 (en) | 2018-01-29 | 2021-11-17 | ModernaTX, Inc. | RSV RNA Vaccines |
| WO2019169120A1 (en) | 2018-02-28 | 2019-09-06 | University Of Washington | Self-asssembling nanostructure vaccines |
| CN113423718A (zh) | 2019-02-08 | 2021-09-21 | 美国政府(由卫生和人类服务部的部长所代表) | 基于纳米颗粒的流感病毒疫苗及其用途 |
| EP4025587A1 (en) * | 2019-09-04 | 2022-07-13 | University of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus f proteins and their use |
| CN110878128A (zh) * | 2019-11-04 | 2020-03-13 | 中国疾病预防控制中心病毒病预防控制所 | 一种人呼吸道合胞病毒粘膜疫苗及其制备方法和应用 |
| JP2023513073A (ja) * | 2020-01-30 | 2023-03-30 | モデルナティエックス インコーポレイテッド | 呼吸器系ウイルス免疫化組成物 |
| PE20230486A1 (es) * | 2020-02-14 | 2023-03-21 | Univ Washington | Polipeptidos y sus usos |
| WO2021163438A1 (en) * | 2020-02-14 | 2021-08-19 | University Of Washington | Polypeptides, compositions, and their use to treat or limit development of an infection |
| KR20230044394A (ko) * | 2020-06-09 | 2023-04-04 | 아이코사백스, 인크. | 바이러스 유사 입자를 제조하는 방법 |
| MX2022015593A (es) * | 2020-06-09 | 2023-04-03 | Icosavax Inc | Metodo de ensamblaje de particulas similares a virus de dos componentes. |
| KR102860080B1 (ko) | 2020-10-09 | 2025-09-15 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 융합전-안정화된 hmpv f 단백질 |
| CN111991556B (zh) * | 2020-10-29 | 2021-03-02 | 中山大学 | SARS-CoV-2 RBD共轭纳米颗粒疫苗 |
| AU2021380755A1 (en) | 2020-11-13 | 2023-06-22 | Icosavax, Inc. | Protein-based nanoparticle vaccine for metapneumovirus |
| CN112778404B (zh) * | 2021-01-28 | 2022-11-29 | 中山大学 | 一种含EB病毒gHgL蛋白的自组装纳米颗粒及其制备方法与应用 |
| IL310628A (en) * | 2021-08-10 | 2024-04-01 | Icosavax Inc | Virus-like particle vaccine for respiratory syncytial virus |
| KR20250025527A (ko) | 2022-05-17 | 2025-02-21 | 아이코사백스, 인크. | 파라믹소바이러스용 다가 백신 및 이의 용도 |
| WO2024118544A2 (en) * | 2022-11-29 | 2024-06-06 | The Scripps Research Institute | Vaccines containing novel nanoparticle scaffolds |
| WO2024131862A1 (zh) * | 2022-12-22 | 2024-06-27 | 北京吉诺卫生物科技有限公司 | 一种rsv疫苗及其制备方法与应用 |
| CN118108812B (zh) * | 2023-05-04 | 2025-04-15 | 国药中生生物技术研究院有限公司 | Rsv f蛋白的突变体 |
| IL325774A (en) * | 2023-07-18 | 2026-03-01 | Astrazeneca Ab | RSV vaccine |
| CN119930762A (zh) * | 2023-11-03 | 2025-05-06 | 广东蓝玉生物科技有限公司 | 非洲猪瘟病毒ep153r蛋白的免疫原性组合物及其应用 |
| CN121758570A (zh) * | 2023-11-03 | 2026-03-31 | 广东蓝玉生物科技有限公司 | 非洲猪瘟病毒CD2v蛋白的免疫原性组合物及其应用 |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4238904A1 (de) | 1992-11-19 | 1994-05-26 | Basf Ag | Riboflavin-Synthese in Hefen |
| US6262202B1 (en) | 1998-03-04 | 2001-07-17 | Univation Technologies, Llc | Noncoordinating anions for olefin polymerization |
| US6303767B1 (en) | 1998-11-05 | 2001-10-16 | Kosan Biosciences, Inc. | Nucleic acids encoding narbonolide polyketide synthase enzymes from streptomyces narbonensis |
| JP2000152791A (ja) | 1998-11-11 | 2000-06-06 | E I Du Pont De Nemours & Co | ルマジンシンターゼおよびリボフラビンシンターゼ |
| US20040005672A1 (en) | 2002-02-22 | 2004-01-08 | Santi Daniel V. | Heterologous production of polyketides |
| WO2004024744A2 (en) | 2002-07-31 | 2004-03-25 | The Board Of Trustees Of The Leland Stanford Junior University | Production of glycosylated macrolides in e. coli |
| EP1773303A2 (en) | 2004-05-25 | 2007-04-18 | Chimeracore, Inc. | Self-assembling nanoparticle drug delivery system |
| EP1793850A4 (en) | 2004-09-21 | 2010-06-30 | Medimmune Inc | ANTIBODIES TO THE METHOD AND METHOD FOR THE PRODUCTION OF VACCINES AGAINST THE RESPIRATORY SYNCYTIAL VIRUS |
| JP5711972B2 (ja) | 2007-12-24 | 2015-05-07 | アイディー バイオメディカル コーポレイション オブ ケベック | 組換えｒｓｖ抗原 |
| US9102526B2 (en) | 2008-08-12 | 2015-08-11 | Imiplex Llc | Node polypeptides for nanostructure assembly |
| WO2010019725A2 (en) | 2008-08-12 | 2010-02-18 | Salemme Francis R | Node polypeptides for nanostructure assembly |
| GB0817507D0 (en) | 2008-09-24 | 2008-10-29 | Ucl Business Plc | Protein cages |
| PL2370099T3 (pl) | 2008-12-09 | 2016-10-31 | Zmodyfikowane białka F RSV i sposoby ich zastosowania | |
| US20110200560A1 (en) | 2009-05-26 | 2011-08-18 | Massachusetts Institute Of Technology | Non-ionic self-assembling peptides and uses thereof |
| WO2011017835A1 (en) | 2009-08-11 | 2011-02-17 | Nanjing University | Preparation method of protein or peptide nanoparticles for in vivo drug delivery by unfolding and refolding |
| US8920812B2 (en) | 2009-11-03 | 2014-12-30 | Takeda Vaccines, Inc. | Chimeric RSV-F polypeptide and lentivirus or alpha-retrovirus Gag-based VLPS |
| CN106008716B (zh) | 2010-07-07 | 2019-08-13 | 人工细胞科技公司 | 呼吸道合胞病毒抗原组合物和方法 |
| CN103282378B (zh) * | 2010-10-06 | 2015-03-11 | 华盛顿大学商业中心 | 多肽及其在治疗和限制呼吸道合胞病毒感染中的用途 |
| CA2835644C (en) | 2011-05-13 | 2021-06-15 | Novartis Ag | Pre-fusion rsv f antigens |
| EP2758038B1 (en) | 2011-09-23 | 2018-05-30 | The United States of America, as represented by The Secretary, Department of Health & Human Services | Novel influenza hemagglutinin protein-based vaccines |
| RU2014117068A (ru) | 2011-09-30 | 2015-11-10 | Новавакс, Инк. | Вакцина на основе рекомбинантных наночастиц f из rsv против респираторно-синцитиального вируса |
| WO2013056122A1 (en) | 2011-10-12 | 2013-04-18 | University Of Washington | Engineered outer domain (eod) of hv gp120 and mutants thereof |
| HK1210479A1 (en) | 2012-04-10 | 2016-04-22 | The Trustees Of The University Of Pennsylvania | Human respiratory syncytial virus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same |
| US8969521B2 (en) | 2012-04-11 | 2015-03-03 | University Of Washington Through Its Center For Commercialization | General method for designing self-assembling protein nanomaterials |
| WO2014005643A1 (en) | 2012-07-05 | 2014-01-09 | Okairos Ag | Novel prime-boosting regimens involving immunogenic polypeptides encoded by polynucleotides |
| CA2878344A1 (en) | 2012-07-06 | 2014-01-09 | Novartis Ag | Complexes of cytomegalovirus proteins |
| KR102435054B1 (ko) | 2012-08-01 | 2022-08-22 | 버베리안 노딕 에이/에스 | 재조합 변형된 백시니아 바이러스 앙카라(ankara) (mva) 호흡기 신시티알 바이러스(rsv) 백신 |
| US20140141037A1 (en) | 2012-11-20 | 2014-05-22 | Novartis Ag | Rsv f prefusion trimers |
| EP2922570A1 (en) | 2012-11-20 | 2015-09-30 | GlaxoSmithKline Biologicals SA | Rsv f prefusion trimers |
| US10248758B2 (en) | 2013-02-07 | 2019-04-02 | University Of Washington Through Its Center For Commercialization | Self-assembling protein nanostructures |
| US9738689B2 (en) | 2013-03-13 | 2017-08-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Prefusion RSV F proteins and their use |
| EP2970398B1 (en) * | 2013-03-13 | 2024-05-08 | The United States of America, as Represented by The Secretary, Department of Health and Human Services | Prefusion rsv f proteins and their use |
| US9060975B2 (en) | 2013-03-14 | 2015-06-23 | Mucosis Bv | Heat-stable respiratory syncytial virus F protein oligomers and their use in immunological compositions |
| EP2975052B1 (en) * | 2013-03-15 | 2020-09-23 | Xiamen University | Epitope of rsv fusion protein and antibody identifying same |
| KR102236497B1 (ko) | 2013-04-25 | 2021-04-06 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 가용성 예비융합 ｒｓｖ ｆ 폴리펩타이드 |
| CN105408348B (zh) | 2013-06-17 | 2021-07-06 | 扬森疫苗与预防公司 | 稳定化的可溶性融合前rsv f多肽 |
| CN104436202B (zh) | 2013-09-12 | 2017-07-28 | 中国科学院深圳先进技术研究院 | 聚合物纳米颗粒、其制备方法及疫苗组合物、疫苗制剂及其制备方法 |
| JP2016533332A (ja) * | 2013-09-24 | 2016-10-27 | マサチューセッツ インスティテュート オブ テクノロジー | 自己集合型ナノ粒子ワクチン |
| US20150166610A1 (en) | 2013-10-14 | 2015-06-18 | Glaxosmithkline Biologicals, S.A. | Recombinant rsv antigens |
| JP6652500B2 (ja) | 2014-01-09 | 2020-02-26 | アルファ−オ ペプティデス アクツィエンゲゼルシャフト | ワクチンプラットフォームとしてのフラジェリン含有タンパク質ナノ粒子 |
| EP2974739A1 (en) * | 2014-07-15 | 2016-01-20 | Novartis AG | RSVF trimerization domains |
| EA035375B1 (ru) | 2014-07-10 | 2020-06-03 | Янссен Вэксинс Энд Превеншн Б.В. | Вакцины против вируса гриппа и их применения |
| US9630994B2 (en) | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
| US11191727B2 (en) | 2014-12-31 | 2021-12-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Multivalent nanoparticle-based vaccines |
| WO2016138525A1 (en) | 2015-02-27 | 2016-09-01 | University Of Washington | Polypeptide assemblies and methods for the production thereof |
| WO2016160166A1 (en) | 2015-03-30 | 2016-10-06 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Immunogenic rsv polypeptides |
| EA039065B1 (ru) | 2015-07-07 | 2021-11-29 | Янссен Вэксинс Энд Превеншн Б.В. | Вакцина против rsv |
| US10457708B2 (en) | 2015-07-07 | 2019-10-29 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion RSV F polypeptides |
| WO2017027480A1 (en) | 2015-08-13 | 2017-02-16 | Echogen Power Systems, L.L.C. | Heat engine system including an integrated cooling circuit |
| CA2996762A1 (en) | 2015-08-31 | 2017-03-09 | Technovax, Inc. | Human respiratory syncytial virus (hrsv) virus-like particles (vlps) based vaccine |
| CA2996007A1 (en) | 2015-09-03 | 2017-03-09 | Novavax, Inc. | Vaccine compositions having improved stability and immunogenicity |
| US10688175B2 (en) | 2015-10-13 | 2020-06-23 | Daniel C. Carter | NSP10 self-assembling fusion proteins for vaccines, therapeutics, diagnostics and other nanomaterial applications |
| EP4011451A1 (en) | 2015-10-22 | 2022-06-15 | ModernaTX, Inc. | Metapneumovirus mrna vaccines |
| MX2018005462A (es) | 2015-10-29 | 2018-08-01 | Univ Emory | Composiciones inmunogénicas de rsv quimérico y métodos de uso. |
| RU2723039C2 (ru) | 2015-12-23 | 2020-06-08 | Пфайзер Инк. | Мутанты белка f rsv |
| WO2017172890A1 (en) | 2016-03-29 | 2017-10-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Substitutions-modified prefusion rsv f proteins and their use |
| IL262108B2 (en) | 2016-04-05 | 2023-04-01 | Janssen Vaccines Prevention B V | Soluble pre-fusion rsv f proteins are stabilized |
| CN109311946A (zh) | 2016-05-30 | 2019-02-05 | 扬森疫苗与预防公司 | 稳定化的融合前rsv f蛋白 |
| WO2017207477A1 (en) | 2016-05-30 | 2017-12-07 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv f proteins |
| US10961283B2 (en) | 2016-06-27 | 2021-03-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Self-assembling insect ferritin nanoparticles for display of co-assembled trimeric antigens |
| US11084850B2 (en) | 2016-12-16 | 2021-08-10 | The Pirbright Institute | Recombinant prefusion RSV F proteins and uses thereof |
| HUE073526T2 (hu) | 2017-04-04 | 2026-01-28 | Univ Washington | Önmagát összeállító fehérje nanostruktúrák, amelyek paramyxovírus és/vagy pneumovírus F fehérjéket jelenítenek meg és azok használata |
| CN107157933B (zh) | 2017-05-04 | 2021-05-11 | 同济大学 | 一种蛋白自组装新型纳米疫苗及其制备方法 |
| WO2019169120A1 (en) * | 2018-02-28 | 2019-09-06 | University Of Washington | Self-asssembling nanostructure vaccines |
-
2018
- 2018-04-03 HU HUE18723094A patent/HUE073526T2/hu unknown
- 2018-04-03 SI SI201831259T patent/SI3606942T1/sl unknown
- 2018-04-03 CA CA3058794A patent/CA3058794A1/en active Pending
- 2018-04-03 CN CN202310044111.1A patent/CN115779077A/zh active Pending
- 2018-04-03 EP EP25152898.0A patent/EP4559869A3/en active Pending
- 2018-04-03 JP JP2019554692A patent/JP7168938B2/ja active Active
- 2018-04-03 WO PCT/US2018/025880 patent/WO2018187325A1/en not_active Ceased
- 2018-04-03 CN CN202310044118.3A patent/CN115947873A/zh active Pending
- 2018-04-03 US US16/500,331 patent/US11192926B2/en active Active
- 2018-04-03 BR BR112019020661-2A patent/BR112019020661A2/pt unknown
- 2018-04-03 RS RS20250807A patent/RS67190B1/sr unknown
- 2018-04-03 DK DK18723094.1T patent/DK3606942T3/da active
- 2018-04-03 CN CN201880023734.8A patent/CN110603262A/zh active Pending
- 2018-04-03 FI FIEP18723094.1T patent/FI3606942T3/fi active
- 2018-04-03 KR KR1020197029815A patent/KR102774312B1/ko active Active
- 2018-04-03 HR HRP20251060TT patent/HRP20251060T1/hr unknown
- 2018-04-03 PL PL18723094.1T patent/PL3606942T3/pl unknown
- 2018-04-03 PT PT187230941T patent/PT3606942T/pt unknown
- 2018-04-03 AU AU2018249533A patent/AU2018249533C1/en active Active
- 2018-04-03 ES ES18723094T patent/ES3040563T3/es active Active
- 2018-04-03 MX MX2019011869A patent/MX2019011869A/es unknown
- 2018-04-03 KR KR1020247035024A patent/KR20240161683A/ko active Pending
- 2018-04-03 SG SG11201908999Q patent/SG11201908999QA/en unknown
- 2018-04-03 SM SM20250317T patent/SMT202500317T1/it unknown
- 2018-04-03 LT LTEPPCT/US2018/025880T patent/LT3606942T/lt unknown
- 2018-04-03 IL IL322023A patent/IL322023A/en unknown
- 2018-04-03 EP EP18723094.1A patent/EP3606942B1/en active Active
-
2019
- 2019-09-25 IL IL26964319A patent/IL269643A/en unknown
- 2019-10-02 PH PH12019502276A patent/PH12019502276A1/en unknown
- 2019-10-02 MX MX2023004704A patent/MX2023004704A/es unknown
-
2021
- 2021-11-10 US US17/523,174 patent/US11732011B2/en active Active
-
2022
- 2022-04-27 AU AU2022202787A patent/AU2022202787C1/en active Active
- 2022-10-19 JP JP2022167524A patent/JP7541701B2/ja active Active
-
2023
- 2023-06-20 US US18/337,881 patent/US12275757B2/en active Active
-
2024
- 2024-08-08 JP JP2024132065A patent/JP2024160321A/ja active Pending
- 2024-09-26 AU AU2024220089A patent/AU2024220089A1/en active Pending
-
2025
- 2025-03-12 US US19/077,674 patent/US20250263445A1/en active Pending