JP2020514351A5 - - Google Patents

Info

Publication number

JP2020514351A5

JP2020514351A5 JP2019550158A JP2019550158A JP2020514351A5 JP 2020514351 A5 JP2020514351 A5 JP 2020514351A5 JP 2019550158 A JP2019550158 A JP 2019550158A JP 2019550158 A JP2019550158 A JP 2019550158A JP 2020514351 A5 JP2020514351 A5 JP 2020514351A5

Authority

JP

Japan

Prior art keywords

stannous

complex

mol

tin

per mole

Prior art date

2018-03-14

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 108010001441 Phosphopeptides Proteins 0.000 claims 19
• ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 claims 15
• 238000000034 method Methods 0.000 claims 15
• 239000000203 mixture Substances 0.000 claims 10
• 239000000243 solution Substances 0.000 claims 7
• 150000001875 compounds Chemical class 0.000 claims 5
• 201000002170 dentin sensitivity Diseases 0.000 claims 5
• IUTCEZPPWBHGIX-UHFFFAOYSA-N tin(2+) Chemical compound [Sn+2] IUTCEZPPWBHGIX-UHFFFAOYSA-N 0.000 claims 5
• 210000004268 dentin Anatomy 0.000 claims 4
• 239000000606 toothpaste Substances 0.000 claims 4
• BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 3
• 229910001424 calcium ion Inorganic materials 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 3
• 238000004519 manufacturing process Methods 0.000 claims 3
• 239000002324 mouth wash Substances 0.000 claims 3
• NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 3
• 229910001432 tin ion Inorganic materials 0.000 claims 3
• 229940034610 toothpaste Drugs 0.000 claims 3
• 210000005239 tubule Anatomy 0.000 claims 3
• 206010020751 Hypersensitivity Diseases 0.000 claims 2
• 208000026935 allergic disease Diseases 0.000 claims 2
• -1 fluoride ions Chemical class 0.000 claims 2
• 230000009610 hypersensitivity Effects 0.000 claims 2
• 210000000214 mouth Anatomy 0.000 claims 2
• 229940051866 mouthwash Drugs 0.000 claims 2
• 229940085991 phosphate ion Drugs 0.000 claims 2
• 230000002265 prevention Effects 0.000 claims 2
• KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims 1
• 239000002253 acid Substances 0.000 claims 1
• 229910000389 calcium phosphate Inorganic materials 0.000 claims 1
• 239000001506 calcium phosphate Substances 0.000 claims 1
• 235000011010 calcium phosphates Nutrition 0.000 claims 1
• 239000005018 casein Substances 0.000 claims 1
• BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims 1
• 235000021240 caseins Nutrition 0.000 claims 1
• 229940112822 chewing gum Drugs 0.000 claims 1
• 235000015218 chewing gum Nutrition 0.000 claims 1
• 239000006071 cream Substances 0.000 claims 1
• 239000003479 dental cement Substances 0.000 claims 1
• 210000003298 dental enamel Anatomy 0.000 claims 1
• GUYBGCBOZOALMT-UHFFFAOYSA-J dicalcium;fluoride;phosphate Chemical compound [F-].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O GUYBGCBOZOALMT-UHFFFAOYSA-J 0.000 claims 1
• 239000003085 diluting agent Substances 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 235000013305 food Nutrition 0.000 claims 1
• 238000009472 formulation Methods 0.000 claims 1
• 239000007788 liquid Substances 0.000 claims 1
• 235000013336 milk Nutrition 0.000 claims 1
• 239000008267 milk Substances 0.000 claims 1
• 210000004080 milk Anatomy 0.000 claims 1
• 239000002674 ointment Substances 0.000 claims 1
• 239000000546 pharmaceutical excipient Substances 0.000 claims 1
• 239000007921 spray Substances 0.000 claims 1
• QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 1
• 239000002966 varnish Substances 0.000 claims 1