JP2020514326A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020514326A5 JP2020514326A5 JP2019546002A JP2019546002A JP2020514326A5 JP 2020514326 A5 JP2020514326 A5 JP 2020514326A5 JP 2019546002 A JP2019546002 A JP 2019546002A JP 2019546002 A JP2019546002 A JP 2019546002A JP 2020514326 A5 JP2020514326 A5 JP 2020514326A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023000606A JP2023036953A (ja) | 2017-02-24 | 2023-01-05 | 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762463216P | 2017-02-24 | 2017-02-24 | |
| US62/463,216 | 2017-02-24 | ||
| US201762555444P | 2017-09-07 | 2017-09-07 | |
| US62/555,444 | 2017-09-07 | ||
| PCT/US2018/018729 WO2018156491A1 (en) | 2017-02-24 | 2018-02-20 | Enhancing immunogenicity of streptococcus pneumoniae polysaccharide-protein conjugates |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023000606A Division JP2023036953A (ja) | 2017-02-24 | 2023-01-05 | 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020514326A JP2020514326A (ja) | 2020-05-21 |
| JP2020514326A5 true JP2020514326A5 (ja) | 2020-10-08 |
Family
ID=63254065
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019546002A Pending JP2020514326A (ja) | 2017-02-24 | 2018-02-20 | 肺炎連鎖球菌多糖−タンパク質コンジュゲートの免疫原性の増強 |
| JP2023000606A Pending JP2023036953A (ja) | 2017-02-24 | 2023-01-05 | 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023000606A Pending JP2023036953A (ja) | 2017-02-24 | 2023-01-05 | 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US11090374B2 (ja) |
| EP (1) | EP3589314A4 (ja) |
| JP (2) | JP2020514326A (ja) |
| KR (2) | KR20240011879A (ja) |
| CN (1) | CN110337307A (ja) |
| AU (1) | AU2018225099A1 (ja) |
| BR (1) | BR112019017560A2 (ja) |
| CA (1) | CA3050120A1 (ja) |
| MX (3) | MX2019009867A (ja) |
| WO (1) | WO2018156491A1 (ja) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006235013B2 (en) * | 2005-04-08 | 2011-11-03 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US10105431B2 (en) * | 2014-01-21 | 2018-10-23 | Pfizer Inc. | Streptococcus pneumoniae capsular polysaccharides and conjugates thereof |
| US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| KR102225282B1 (ko) * | 2015-07-21 | 2021-03-10 | 화이자 인코포레이티드 | 접합된 캡슐형 사카라이드 항원을 포함하는 면역원성 조성물, 그를 포함하는 키트 및 그의 용도 |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| EP3562503A2 (en) | 2016-12-30 | 2019-11-06 | Sutrovax, Inc. | Polypeptide-antigen conjugates with non-natural amino acids |
| EP3576759A4 (en) * | 2017-01-31 | 2020-11-11 | Merck Sharp & Dohme Corp. | PROCESS FOR THE PREPARATION OF CAPSULE POLYSACCHARIDE PROTEIN CONJUGATES FROM STREPTOCOCCUS PNEUMONIAE SEROTYPE 19F |
| US11197921B2 (en) | 2017-01-31 | 2021-12-14 | Merck Sharp & Dohme Corp. | Methods for making polysaccharide-protein conjugates |
| US11400162B2 (en) | 2017-02-24 | 2022-08-02 | Merck Sharp & Dohme Llc | Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein |
| US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
| BR112020004471A8 (pt) | 2017-09-07 | 2022-11-01 | Merck Sharp & Dohme | Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora |
| US11491216B2 (en) * | 2017-09-07 | 2022-11-08 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| US11524076B2 (en) | 2017-09-07 | 2022-12-13 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| KR20200051005A (ko) | 2017-09-07 | 2020-05-12 | 머크 샤프 앤드 돔 코포레이션 | 폐렴구균 폴리사카라이드 및 면역원성 폴리사카라이드-담체 단백질 접합체에서의 그의 용도 |
| CN111683678B (zh) | 2017-12-06 | 2024-01-26 | 默沙东有限责任公司 | 包含肺炎链球菌多糖蛋白缀合物的组合物及其使用方法 |
| KR20210005158A (ko) | 2018-04-30 | 2021-01-13 | 머크 샤프 앤드 돔 코포레이션 | 스트렙토코쿠스 뉴모니아에 피막 폴리사카라이드 담체 단백질 접합체를 제조하는 방법 |
| KR20210002641A (ko) | 2018-04-30 | 2021-01-08 | 머크 샤프 앤드 돔 코포레이션 | 디메틸술폭시드 중의 동결건조된 돌연변이체 디프테리아 독소의 균질 용액을 제공하는 방법 |
| AU2019341723B2 (en) * | 2018-09-23 | 2024-03-21 | Biological E Limited | Purified capsular polysaccharides of Streptococcus pneumoniae |
| CA3123414A1 (en) * | 2018-12-19 | 2020-06-25 | Merck Sharp & Dohme Corp. | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
| US20220184199A1 (en) * | 2019-04-10 | 2022-06-16 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof |
| CA3142692A1 (en) * | 2019-06-05 | 2020-12-10 | Merck Sharp & Dohme Corp. | An immunogenic serotype 35b pneumococcal polysaccharide-protein conjugate and conjugation process for making the same |
| CN110804097B (zh) * | 2019-10-30 | 2021-02-26 | 云南沃森生物技术股份有限公司 | 一种同时制备两种单克隆抗体的方法 |
| EP4101192A4 (en) * | 2020-02-03 | 2024-02-28 | Anagog Ltd. | DELIVERY OF DISTRIBUTED CONTENT |
| EP4243863A2 (en) | 2020-11-10 | 2023-09-20 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| TW202306969A (zh) | 2021-05-28 | 2023-02-16 | 美商輝瑞大藥廠 | 包含結合之莢膜醣抗原的免疫原組合物及其用途 |
| CN114965784B (zh) * | 2022-06-01 | 2023-10-27 | 艾美探索者生命科学研发有限公司 | 多糖活化度的测定方法 |
| WO2024059161A1 (en) * | 2022-09-16 | 2024-03-21 | Merck Sharp & Dohme Llc | Method for quantification of polysaccharide content in conjugate vaccines |
| WO2024110839A2 (en) | 2022-11-22 | 2024-05-30 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0220198D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Modified saccharides,conjugates thereof and their manufacture |
| US20070184072A1 (en) * | 2005-04-08 | 2007-08-09 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US7709001B2 (en) * | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US7955605B2 (en) * | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| JP5049264B2 (ja) | 2005-04-08 | 2012-10-17 | ワイス・エルエルシー | ｐＨ操作によるストレプトコッカス・ニューモニエ多糖からの混入物の分離 |
| AU2006235013B2 (en) | 2005-04-08 | 2011-11-03 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| TW200806315A (en) | 2006-04-26 | 2008-02-01 | Wyeth Corp | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
| US8808707B1 (en) | 2006-05-08 | 2014-08-19 | Wyeth Llc | Pneumococcal dosing regimen |
| MX2009003730A (es) | 2006-10-10 | 2009-04-22 | Wyeth Corp | Purificacion de polisacaridos de streptococcus pneumoniae tipo 3. |
| PL2436700T3 (pl) | 2007-03-23 | 2018-12-31 | Wyeth Llc | Skrócony sposób oczyszczania do wytwarzania polisacharydów otoczkowych Streptococcus pneumoniae |
| US8540955B2 (en) | 2007-07-10 | 2013-09-24 | Wyeth Llc | Process for producing aluminum phosphate |
| HUE037465T2 (hu) | 2008-12-18 | 2018-09-28 | Wyeth Llc | Eljárás 19A szerotípusú streptococcus pneumoniae poliszacharidok molekulatömegének szabályozására |
| RU2524436C2 (ru) | 2008-12-18 | 2014-07-27 | УАЙТ ЭлЭлСи | Способ получения жидкой фракции, содержащей изолированные высокомолекулярные капсульные полисахариды streptococcus pneumoniae, и жидкая фракция, полученная таким способом |
| CA2766418C (en) | 2009-06-22 | 2016-03-29 | Wyeth Llc | Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions |
| TW201136603A (en) | 2010-02-09 | 2011-11-01 | Merck Sharp & Amp Dohme Corp | 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition |
| BR112012030950B1 (pt) | 2010-06-04 | 2020-02-04 | Wyeth Llc | composição imunogênica multivalente, formulação, frasco, dispositivo de distribuição de vacinas pré-enchido, kit, e recipiente |
| AU2011338723A1 (en) | 2010-12-10 | 2013-05-30 | Merck Sharp & Dohme Corp. | Novel formulations which mitigate agitation-induced aggregation of immunogenic compositions |
| KR102057217B1 (ko) * | 2012-06-20 | 2020-01-22 | 에스케이바이오사이언스 주식회사 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
| KR20140075201A (ko) * | 2012-12-11 | 2014-06-19 | 에스케이케미칼주식회사 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
| EP4169929A1 (en) | 2012-12-20 | 2023-04-26 | Pfizer Inc. | Immunogenic compositions comprising pn-serotype 12f |
| MX2016009470A (es) * | 2014-01-21 | 2017-01-18 | Pfizer | Composiciones inmunogenicas que comprenden antigenos sacaridos capsulares conjugados y usos de los mismos. |
| BR122023022294A2 (pt) | 2014-01-21 | 2023-12-12 | Pfizer Inc. | Uso de uma composição imunogênica que compreende um conjugado imunogênico compreendendo um polissacarídeo capsular isolado de streptococcus pneumoniae do sorotipo 15b |
| US10105431B2 (en) * | 2014-01-21 | 2018-10-23 | Pfizer Inc. | Streptococcus pneumoniae capsular polysaccharides and conjugates thereof |
| CA2956188A1 (en) | 2014-08-08 | 2016-02-11 | Glycovaxyn Ag | Modified host cells for use in bioconjugate production |
| US10653764B2 (en) * | 2015-01-15 | 2020-05-19 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| EP3292146A1 (en) | 2015-05-04 | 2018-03-14 | Pfizer Inc | Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof |
| KR102225282B1 (ko) * | 2015-07-21 | 2021-03-10 | 화이자 인코포레이티드 | 접합된 캡슐형 사카라이드 항원을 포함하는 면역원성 조성물, 그를 포함하는 키트 및 그의 용도 |
| RU2021135165A (ru) | 2015-11-17 | 2021-12-29 | Пфайзер Инк. | Среды и способы ферментации для производства полисахаридов в бактериальной клеточной культуре |
| CA3005524C (en) | 2015-11-20 | 2023-10-10 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| CN109862908B (zh) * | 2016-08-05 | 2023-05-02 | 圣诺菲·帕斯图尔公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物 |
| EP3562503A2 (en) * | 2016-12-30 | 2019-11-06 | Sutrovax, Inc. | Polypeptide-antigen conjugates with non-natural amino acids |
| EP3570879B1 (en) | 2017-01-20 | 2022-03-30 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| EP3576759A4 (en) | 2017-01-31 | 2020-11-11 | Merck Sharp & Dohme Corp. | PROCESS FOR THE PREPARATION OF CAPSULE POLYSACCHARIDE PROTEIN CONJUGATES FROM STREPTOCOCCUS PNEUMONIAE SEROTYPE 19F |
| US11197921B2 (en) | 2017-01-31 | 2021-12-14 | Merck Sharp & Dohme Corp. | Methods for making polysaccharide-protein conjugates |
| WO2018156465A1 (en) | 2017-02-24 | 2018-08-30 | Merck Sharp & Dohme Corp. | Polysaccharide-protein conjugates utilizing diphtheria toxin fragment b as a carrier |
| US20200061542A1 (en) | 2017-02-24 | 2020-02-27 | Merck Sharp & Dohme Corp. | Methods for improving filterability of polysaccharide-protein conjugate reactions |
| EP3585803A4 (en) | 2017-02-24 | 2020-11-11 | Merck Sharp & Dohme Corp. | PNEUMOCOCCIC CONJUGATE VACCINE FORMULATIONS |
| WO2019036313A1 (en) | 2017-08-16 | 2019-02-21 | Merck Sharp & Dohme Corp. | CONJUGATED PNEUMOCOCCAL VACCINE FORMULATIONS |
| US11491216B2 (en) * | 2017-09-07 | 2022-11-08 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| BR112020004410A8 (pt) | 2017-09-07 | 2023-01-31 | Merck Sharp & Dohme | Processos para a formulação de polissacarídeos pneumocócicos para conjugação a uma proteína carreadora |
| BR112020004471A8 (pt) | 2017-09-07 | 2022-11-01 | Merck Sharp & Dohme | Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora |
| KR20200051005A (ko) | 2017-09-07 | 2020-05-12 | 머크 샤프 앤드 돔 코포레이션 | 폐렴구균 폴리사카라이드 및 면역원성 폴리사카라이드-담체 단백질 접합체에서의 그의 용도 |
| JP7438102B2 (ja) * | 2017-09-07 | 2024-02-26 | メルク・シャープ・アンド・ドーム・エルエルシー | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
| JP2021501144A (ja) | 2017-10-25 | 2021-01-14 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | アジュバントワクチン |
| CN111683678B (zh) | 2017-12-06 | 2024-01-26 | 默沙东有限责任公司 | 包含肺炎链球菌多糖蛋白缀合物的组合物及其使用方法 |
| KR20210005158A (ko) | 2018-04-30 | 2021-01-13 | 머크 샤프 앤드 돔 코포레이션 | 스트렙토코쿠스 뉴모니아에 피막 폴리사카라이드 담체 단백질 접합체를 제조하는 방법 |
| KR20210002641A (ko) | 2018-04-30 | 2021-01-08 | 머크 샤프 앤드 돔 코포레이션 | 디메틸술폭시드 중의 동결건조된 돌연변이체 디프테리아 독소의 균질 용액을 제공하는 방법 |
| JP7489324B2 (ja) | 2018-04-30 | 2024-05-23 | メルク・シャープ・アンド・ドーム・エルエルシー | リオスフィアから肺炎連鎖球菌莢膜多糖類キャリアタンパク質コンジュゲートを生産する方法 |
| WO2019236435A1 (en) | 2018-06-07 | 2019-12-12 | Merck Sharp & Dohme Corp. | Lyosphere critical reagent kit |
| CA3120922A1 (en) | 2018-12-12 | 2020-06-18 | Pfizer Inc. | Immunogenic multiple hetero-antigen polysaccharide-protein conjugates and uses thereof |
| CA3123414A1 (en) | 2018-12-19 | 2020-06-25 | Merck Sharp & Dohme Corp. | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
| US20220184199A1 (en) | 2019-04-10 | 2022-06-16 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof |
| CA3142692A1 (en) | 2019-06-05 | 2020-12-10 | Merck Sharp & Dohme Corp. | An immunogenic serotype 35b pneumococcal polysaccharide-protein conjugate and conjugation process for making the same |
| BR112021024491A8 (pt) | 2019-06-05 | 2023-04-11 | Merck Sharp & Dohme | Composição imunogênica, e, método para prevenir, tratar ou melhorar uma infecção, doença ou condição |
-
2018
- 2018-02-20 US US16/487,550 patent/US11090374B2/en active Active
- 2018-02-20 AU AU2018225099A patent/AU2018225099A1/en active Pending
- 2018-02-20 WO PCT/US2018/018729 patent/WO2018156491A1/en unknown
- 2018-02-20 CN CN201880013793.7A patent/CN110337307A/zh active Pending
- 2018-02-20 KR KR1020247001331A patent/KR20240011879A/ko active Search and Examination
- 2018-02-20 MX MX2019009867A patent/MX2019009867A/es unknown
- 2018-02-20 KR KR1020197027396A patent/KR20190121330A/ko not_active Application Discontinuation
- 2018-02-20 BR BR112019017560A patent/BR112019017560A2/pt unknown
- 2018-02-20 JP JP2019546002A patent/JP2020514326A/ja active Pending
- 2018-02-20 CA CA3050120A patent/CA3050120A1/en active Pending
- 2018-02-20 EP EP18757315.9A patent/EP3589314A4/en active Pending
-
2019
- 2019-08-19 MX MX2023001948A patent/MX2023001948A/es unknown
- 2019-08-19 MX MX2023001947A patent/MX2023001947A/es unknown
-
2021
- 2021-07-07 US US17/369,177 patent/US20210330777A1/en not_active Abandoned
- 2021-07-07 US US17/369,230 patent/US20210330778A1/en not_active Abandoned
-
2023
- 2023-01-05 JP JP2023000606A patent/JP2023036953A/ja active Pending
- 2023-06-22 US US18/339,723 patent/US20240139303A1/en active Pending