JP2020512284A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020512284A5 JP2020512284A5 JP2019530043A JP2019530043A JP2020512284A5 JP 2020512284 A5 JP2020512284 A5 JP 2020512284A5 JP 2019530043 A JP2019530043 A JP 2019530043A JP 2019530043 A JP2019530043 A JP 2019530043A JP 2020512284 A5 JP2020512284 A5 JP 2020512284A5
- Authority
- JP
- Japan
- Prior art keywords
- intracellular signaling
- domain
- signaling domain
- intracellular
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662438106P | 2016-12-22 | 2016-12-22 | |
| US62/438,106 | 2016-12-22 | ||
| PCT/US2017/067830 WO2018119198A1 (en) | 2016-12-22 | 2017-12-21 | Compositions and methods for modulating the immune system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020512284A JP2020512284A (ja) | 2020-04-23 |
| JP2020512284A5 true JP2020512284A5 (https=) | 2021-02-04 |
Family
ID=62627209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019530043A Pending JP2020512284A (ja) | 2016-12-22 | 2017-12-21 | 免疫系調節組成物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20190330306A1 (https=) |
| EP (1) | EP3525805A4 (https=) |
| JP (1) | JP2020512284A (https=) |
| KR (1) | KR20190096969A (https=) |
| CN (1) | CN110267666A (https=) |
| AU (1) | AU2017382243A1 (https=) |
| CA (1) | CA3038150A1 (https=) |
| IL (1) | IL266386A (https=) |
| MX (1) | MX2019006852A (https=) |
| WO (1) | WO2018119198A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016037054A1 (en) * | 2014-09-04 | 2016-03-10 | The Johns Hopkins University | Activation of marrow infiltrating lymphocytes in hypoxic alternating with normoxic conditions |
| PL3298033T5 (pl) | 2015-05-18 | 2023-10-30 | TCR2 Therapeutics Inc. | Kompozycje i zastosowania medyczne do reprogramowania TCR z zastosowaniem białek fuzyjnych |
| DK3909972T5 (da) | 2015-06-19 | 2024-08-05 | Sebastian Kobold | Pd1-cd28-fusionsproteiner og disses anvendelse i medicin |
| JP7291396B2 (ja) | 2016-11-22 | 2023-06-15 | ティーシーアール２ セラピューティクス インク． | 融合タンパク質を用いたｔｃｒの再プログラミングのための組成物及び方法 |
| WO2020236964A1 (en) * | 2019-05-20 | 2020-11-26 | The Trustees Of The University Of Pennsylvania | Engineered expression of cell surface and secreted sialidase by car t cells for increased efficacy in solid tumors |
| WO2022211376A1 (ko) * | 2021-04-01 | 2022-10-06 | 주식회사 이뮤노로지컬디자이닝랩 | 키메릭 항원 수용체(car)를 포함하는 형질전환된 항원 특이적 전문적 항원표출세포 및 이의 용도 |
| KR20220144000A (ko) * | 2021-04-16 | 2022-10-26 | 주식회사 이뮤노로지컬디자이닝랩 | Programmed death-ligand 1(PD-L1)에 특이적으로 결합하는 키메릭 항원 수용체 및 이의 용도 |
| EP4334331A1 (en) * | 2021-05-07 | 2024-03-13 | Medigene Immunotherapies GmbH | Combination of prame specific t cell receptors and chimeric co-stimulatory receptors |
| CA3240185A1 (en) * | 2021-12-06 | 2023-06-15 | Vycellix, Inc. | Chimeric switch receptors in nk cells |
| WO2025056659A1 (en) * | 2023-09-15 | 2025-03-20 | Medigene Immunotherapies Gmbh | T-CELL RECEPTOR VARIANT AGAINST mKRAS7-16 G12V AND G12C |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2014001222A (es) * | 2011-07-29 | 2014-09-15 | Univ Pennsylvania | Receptores coestimuladores de cambio. |
| US9573988B2 (en) * | 2013-02-20 | 2017-02-21 | Novartis Ag | Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells |
| WO2015048744A2 (en) * | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
| EP4205749A1 (en) * | 2014-07-31 | 2023-07-05 | Novartis AG | Subset-optimized chimeric antigen receptor-containing cells |
| WO2016037054A1 (en) * | 2014-09-04 | 2016-03-10 | The Johns Hopkins University | Activation of marrow infiltrating lymphocytes in hypoxic alternating with normoxic conditions |
| US20180334490A1 (en) * | 2014-12-03 | 2018-11-22 | Qilong H. Wu | Methods for b cell preconditioning in car therapy |
| CN108064251A (zh) * | 2014-12-19 | 2018-05-22 | 达纳－法伯癌症研究所公司 | 碳酸酐酶ix特异性嵌合抗原受体及其使用方法 |
| EP4406604A3 (en) * | 2015-03-05 | 2024-10-23 | Fred Hutchinson Cancer Center | Immunomodulatory fusion proteins and uses thereof |
| CN108064176A (zh) * | 2015-04-22 | 2018-05-22 | 库瑞瓦格股份公司 | 用于治疗肿瘤疾病的含有rna的组合物 |
| WO2016179319A1 (en) * | 2015-05-04 | 2016-11-10 | Cellerant Therapeutics, Inc. | Chimeric antigen receptors with ctla4 signal transduction domains |
| JP2018520679A (ja) * | 2015-06-29 | 2018-08-02 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 免疫チェックポイントキメラ抗原受容体療法 |
| CN105153315B (zh) * | 2015-10-09 | 2019-04-02 | 重庆精准生物技术有限公司 | 免疫抑制受体联合肿瘤抗原嵌合受体及其应用 |
| EP3433269B1 (en) * | 2016-03-23 | 2023-09-27 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Fusion proteins of pd-1 and 4-1bb |
-
2017
- 2017-12-21 AU AU2017382243A patent/AU2017382243A1/en not_active Abandoned
- 2017-12-21 KR KR1020197014105A patent/KR20190096969A/ko not_active Withdrawn
- 2017-12-21 CA CA3038150A patent/CA3038150A1/en not_active Abandoned
- 2017-12-21 EP EP17885380.0A patent/EP3525805A4/en not_active Withdrawn
- 2017-12-21 JP JP2019530043A patent/JP2020512284A/ja active Pending
- 2017-12-21 WO PCT/US2017/067830 patent/WO2018119198A1/en not_active Ceased
- 2017-12-21 US US16/471,854 patent/US20190330306A1/en not_active Abandoned
- 2017-12-21 MX MX2019006852A patent/MX2019006852A/es unknown
- 2017-12-21 CN CN201780079696.3A patent/CN110267666A/zh active Pending
-
2019
- 2019-05-01 IL IL266386A patent/IL266386A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020512284A5 (https=) | ||
| JP2018520679A5 (https=) | ||
| IL292650B2 (en) | COSTIMULATORY CHIMERIC ANTIGEN RECEPTOR T CELLS TARGETING IL13Ra2 | |
| CN106117354B (zh) | 一种全人源抗CD47的全分子IgG抗体及其应用 | |
| IL259120A (en) | Her2-targeted antigen chimeric receptors2 | |
| Acharya et al. | Interleukin-17A promotes CD8+ T cell cytotoxicity to facilitate West Nile virus clearance | |
| JP2023538891A5 (https=) | ||
| JP2022531231A5 (https=) | ||
| JP2017537622A5 (https=) | ||
| JP2016502512A5 (https=) | ||
| MY200749A (en) | Anti-icos agonist antibodies and uses thereof | |
| JP2018500006A5 (https=) | ||
| JP2018518459A5 (https=) | ||
| JP2017538401A5 (https=) | ||
| FI3461261T3 (fi) | Yksiketjuisen vaihtelevan fragmentin sisältäviä cd3:a sitovia proteiineja | |
| JP2018529380A5 (https=) | ||
| JP2014534207A5 (https=) | ||
| JP2017018125A5 (https=) | ||
| JP2020502262A5 (https=) | ||
| JP2019509764A (ja) | 初代細胞のためのトランスポゾンに基づく転移システム | |
| JP2016514457A5 (https=) | ||
| JP2017513478A5 (https=) | ||
| JP2017508744A5 (https=) | ||
| JP2018522579A5 (https=) | ||
| EP4286522A3 (en) | Fusion proteins of pd-1 and 4-1bb |