JP2020510436A5 - - Google Patents
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- Publication number
- JP2020510436A5 JP2020510436A5 JP2019548614A JP2019548614A JP2020510436A5 JP 2020510436 A5 JP2020510436 A5 JP 2020510436A5 JP 2019548614 A JP2019548614 A JP 2019548614A JP 2019548614 A JP2019548614 A JP 2019548614A JP 2020510436 A5 JP2020510436 A5 JP 2020510436A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- malodor
- receptor
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 claims description 22
- 108020004707 nucleic acids Proteins 0.000 claims description 16
- 102000039446 nucleic acids Human genes 0.000 claims description 16
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 12
- 230000000295 complement effect Effects 0.000 claims description 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 6
- 239000013604 expression vector Substances 0.000 claims description 5
- YWHLKYXPLRWGSE-UHFFFAOYSA-N Dimethyl trisulfide Chemical group CSSSC YWHLKYXPLRWGSE-UHFFFAOYSA-N 0.000 claims 22
- WQOXQRCZOLPYPM-UHFFFAOYSA-N dimethyl disulfide Chemical compound CSSC WQOXQRCZOLPYPM-UHFFFAOYSA-N 0.000 claims 20
- 239000000126 substance Substances 0.000 claims 20
- 229920001184 polypeptide Polymers 0.000 claims 13
- 102000004196 processed proteins & peptides Human genes 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 102000012547 Olfactory receptors Human genes 0.000 claims 12
- 108050002069 Olfactory receptors Proteins 0.000 claims 12
- 210000004027 cell Anatomy 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 10
- 102000005962 receptors Human genes 0.000 claims 10
- 108020003175 receptors Proteins 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 5
- 101000990753 Homo sapiens Olfactory receptor 52N5 Proteins 0.000 claims 4
- 102100030578 Olfactory receptor 52N5 Human genes 0.000 claims 4
- 101001121144 Homo sapiens Olfactory receptor 2L13 Proteins 0.000 claims 3
- 102100026579 Olfactory receptor 2L13 Human genes 0.000 claims 3
- 101000594462 Homo sapiens Olfactory receptor 2AJ1 Proteins 0.000 claims 2
- -1 OR2OR Proteins 0.000 claims 2
- 102100035516 Olfactory receptor 2AJ1 Human genes 0.000 claims 2
- 101000614009 Homo sapiens Olfactory receptor 4S2 Proteins 0.000 claims 1
- 101000992264 Homo sapiens Olfactory receptor 5T1 Proteins 0.000 claims 1
- 102100040567 Olfactory receptor 4S2 Human genes 0.000 claims 1
- 102100031852 Olfactory receptor 5T1 Human genes 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 235000019645 odor Nutrition 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023010950A JP7662685B2 (ja) | 2017-03-09 | 2023-01-27 | 悪臭調節化合物の同定方法 |
| JP2025061793A JP2025106387A (ja) | 2017-03-09 | 2025-04-03 | 悪臭調節化合物の同定方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762469256P | 2017-03-09 | 2017-03-09 | |
| US62/469,256 | 2017-03-09 | ||
| PCT/EP2018/055753 WO2018162638A1 (en) | 2017-03-09 | 2018-03-08 | Method of identifying malodor modulating compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023010950A Division JP7662685B2 (ja) | 2017-03-09 | 2023-01-27 | 悪臭調節化合物の同定方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020510436A JP2020510436A (ja) | 2020-04-09 |
| JP2020510436A5 true JP2020510436A5 (enExample) | 2021-03-25 |
| JP7606816B2 JP7606816B2 (ja) | 2024-12-26 |
Family
ID=61911520
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019548614A Active JP7606816B2 (ja) | 2017-03-09 | 2018-03-08 | 悪臭調節化合物の同定方法 |
| JP2023010950A Active JP7662685B2 (ja) | 2017-03-09 | 2023-01-27 | 悪臭調節化合物の同定方法 |
| JP2025061793A Pending JP2025106387A (ja) | 2017-03-09 | 2025-04-03 | 悪臭調節化合物の同定方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023010950A Active JP7662685B2 (ja) | 2017-03-09 | 2023-01-27 | 悪臭調節化合物の同定方法 |
| JP2025061793A Pending JP2025106387A (ja) | 2017-03-09 | 2025-04-03 | 悪臭調節化合物の同定方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11787847B2 (enExample) |
| EP (1) | EP3592766A1 (enExample) |
| JP (3) | JP7606816B2 (enExample) |
| CN (2) | CN117330756A (enExample) |
| BR (1) | BR112019018196A2 (enExample) |
| SG (1) | SG11201907884XA (enExample) |
| WO (1) | WO2018162638A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7606816B2 (ja) * | 2017-03-09 | 2024-12-26 | フイルメニツヒ ソシエテ アノニム | 悪臭調節化合物の同定方法 |
| JP7770307B2 (ja) * | 2019-10-04 | 2025-11-14 | フイルメニツヒ ソシエテ アノニム | 嗅覚香調を嗅覚受容体活性化に割り当てる方法および割り当てられた香調を有する化合物を同定する方法 |
| JP7658911B2 (ja) * | 2019-11-01 | 2025-04-08 | 高砂香料工業株式会社 | 悪臭抑制素材のスクリーニング方法 |
| US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
| US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
| US12269315B2 (en) | 2020-08-20 | 2025-04-08 | Denso International America, Inc. | Systems and methods for measuring and managing odor brought into rental vehicles |
| US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
| US12251991B2 (en) | 2020-08-20 | 2025-03-18 | Denso International America, Inc. | Humidity control for olfaction sensors |
| US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
| US12377711B2 (en) | 2020-08-20 | 2025-08-05 | Denso International America, Inc. | Vehicle feature control systems and methods based on smoking |
| US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
| US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
| US12017506B2 (en) | 2020-08-20 | 2024-06-25 | Denso International America, Inc. | Passenger cabin air control systems and methods |
| US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
| WO2022270481A1 (ja) | 2021-06-22 | 2022-12-29 | 花王株式会社 | 嗅覚受容体の発現方法及び応答測定方法 |
| JP2023084475A (ja) * | 2021-12-07 | 2023-06-19 | 花王株式会社 | カルボン酸を原因とするにおいの抑制剤の評価及び／又は選択方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003094088A1 (en) * | 2001-08-09 | 2003-11-13 | The Trustees Of Columbia University In The City Of New York | Mouse olfactory receptor gene superfamily specification |
| MX371282B (es) | 2013-06-29 | 2020-01-24 | Firmenich & Cie | Metodos para identificar, aislar y usar receptores de odorizantes y aroma. |
| JP6449157B2 (ja) | 2013-08-09 | 2019-01-09 | 国立大学法人 東京大学 | ムスク系香料のスクリーニング方法 |
| EP3726218B1 (en) | 2015-06-10 | 2023-08-09 | Firmenich Sa | Cell lines for screening odorant and aroma receptors |
| US10913787B2 (en) | 2015-06-10 | 2021-02-09 | Firmenich Sa | Method of identifying musk compounds |
| WO2016204211A1 (ja) | 2015-06-17 | 2016-12-22 | 花王株式会社 | スルフィド化合物の臭いの抑制剤の評価又は選択方法 |
| JP6371336B2 (ja) * | 2015-06-17 | 2018-08-08 | 花王株式会社 | ポリスルフィド化合物の臭いの抑制剤 |
| JP6920786B2 (ja) | 2015-08-26 | 2021-08-18 | ドイチェス クレブスフォルシュンクスツェントルム | 免疫ウイルス療法のためのｒｎａウイルス |
| JP7606816B2 (ja) * | 2017-03-09 | 2024-12-26 | フイルメニツヒ ソシエテ アノニム | 悪臭調節化合物の同定方法 |
-
2018
- 2018-03-08 JP JP2019548614A patent/JP7606816B2/ja active Active
- 2018-03-08 WO PCT/EP2018/055753 patent/WO2018162638A1/en not_active Ceased
- 2018-03-08 CN CN202311093055.7A patent/CN117330756A/zh active Pending
- 2018-03-08 US US16/492,115 patent/US11787847B2/en active Active
- 2018-03-08 SG SG11201907884XA patent/SG11201907884XA/en unknown
- 2018-03-08 EP EP18716115.3A patent/EP3592766A1/en active Pending
- 2018-03-08 CN CN201880016397.XA patent/CN110418801B/zh active Active
- 2018-03-08 BR BR112019018196-2A patent/BR112019018196A2/pt not_active Application Discontinuation
-
2023
- 2023-01-27 JP JP2023010950A patent/JP7662685B2/ja active Active
- 2023-10-13 US US18/486,417 patent/US20240117001A1/en not_active Abandoned
-
2025
- 2025-04-03 JP JP2025061793A patent/JP2025106387A/ja active Pending
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