JP2020508468A5 - - Google Patents

Download PDF

Info

Publication number
JP2020508468A5
JP2020508468A5 JP2019563338A JP2019563338A JP2020508468A5 JP 2020508468 A5 JP2020508468 A5 JP 2020508468A5 JP 2019563338 A JP2019563338 A JP 2019563338A JP 2019563338 A JP2019563338 A JP 2019563338A JP 2020508468 A5 JP2020508468 A5 JP 2020508468A5
Authority
JP
Japan
Prior art keywords
particles
flow
detector
particle
trigger
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019563338A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020508468A (ja
JP7366754B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/017036 external-priority patent/WO2018148194A1/en
Publication of JP2020508468A publication Critical patent/JP2020508468A/ja
Publication of JP2020508468A5 publication Critical patent/JP2020508468A5/ja
Priority to JP2023175614A priority Critical patent/JP7527453B2/ja
Application granted granted Critical
Publication of JP7366754B2 publication Critical patent/JP7366754B2/ja
Priority to JP2024117735A priority patent/JP2024167184A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2019563338A 2017-02-07 2018-02-06 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法 Active JP7366754B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023175614A JP7527453B2 (ja) 2017-02-07 2023-10-11 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法
JP2024117735A JP2024167184A (ja) 2017-02-07 2024-07-23 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762456069P 2017-02-07 2017-02-07
US62/456,069 2017-02-07
PCT/US2018/017036 WO2018148194A1 (en) 2017-02-07 2018-02-06 Microfluidic system with combined electrical and optical detection for high accuracy particle sorting and methods thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023175614A Division JP7527453B2 (ja) 2017-02-07 2023-10-11 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法

Publications (3)

Publication Number Publication Date
JP2020508468A JP2020508468A (ja) 2020-03-19
JP2020508468A5 true JP2020508468A5 (https=) 2021-03-18
JP7366754B2 JP7366754B2 (ja) 2023-10-23

Family

ID=63107803

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019563338A Active JP7366754B2 (ja) 2017-02-07 2018-02-06 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法
JP2023175614A Active JP7527453B2 (ja) 2017-02-07 2023-10-11 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法
JP2024117735A Pending JP2024167184A (ja) 2017-02-07 2024-07-23 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023175614A Active JP7527453B2 (ja) 2017-02-07 2023-10-11 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法
JP2024117735A Pending JP2024167184A (ja) 2017-02-07 2024-07-23 高精度粒子選別のための電気的検出と光学的検出を組み合わせたマイクロ流体システム、およびその方法

Country Status (4)

Country Link
US (6) US11579073B2 (https=)
EP (1) EP3579973A4 (https=)
JP (3) JP7366754B2 (https=)
WO (1) WO2018148194A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3933378A4 (en) * 2019-02-27 2022-11-30 Kyocera Corporation PARTICLE SEPARATION AND MEASURING DEVICE AND PARTICLE SEPARATION AND MEASURING DEVICE
WO2020219800A1 (en) 2019-04-24 2020-10-29 Bennubio Inc. Positionally assisted negative particle rejection (panr) to sort and enrich target cells of interest
CN114729872A (zh) * 2019-11-20 2022-07-08 索尼集团公司 微芯片、样本分选试剂盒和微粒分选装置
JP7477378B2 (ja) 2020-06-19 2024-05-01 シスメックス株式会社 粒子ソーター、粒子分取方法およびマイクロ流路カートリッジ
DK181994B1 (en) * 2021-09-28 2025-05-15 Samplix Aps Instrument for sorting of particles
EP4255632A1 (en) * 2020-12-01 2023-10-11 Samplix ApS System and method for sorting of particles
TWI785543B (zh) * 2021-03-18 2022-12-01 歐陽自坤 生物粒子檢測系統及檢測方法
GB2621756B (en) * 2021-04-27 2026-04-01 Boe Technology Group Co Ltd Microfluidic chip, box body device, and microfluidic device
US20230285970A1 (en) * 2022-03-11 2023-09-14 Hewlett-Packard Development Company, L.P. Apparatuses with fluid droplet generators coupled to reaction regions and fluid ejectors
WO2024064914A1 (en) 2022-09-22 2024-03-28 Sigil Biosciences, Inc. Devices and systems for isolating particles in solution by particle permitivity
CN115468942B (zh) * 2022-09-22 2025-09-09 深圳高性能医疗器械国家研究院有限公司 一种单分子荧光检测系统及锥形毛细微管制备方法
WO2024155709A1 (en) * 2023-01-18 2024-07-25 Nodexus Inc. Microfluidic particle sorting
CN116207194B (zh) * 2023-05-05 2023-08-01 武汉精立电子技术有限公司 一种Mini LED芯片自动化制程装置及方法
WO2025106429A1 (en) * 2023-11-15 2025-05-22 Generate Biomedicines, Inc. Systems and methods for image-based cell sorting

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE48477T1 (de) * 1984-09-11 1989-12-15 Partec Ag Verfahren und vorrichtung zur sortierung von mikroskopischen partikeln.
JPS61160038A (ja) 1985-01-08 1986-07-19 Sumitomo Electric Ind Ltd 粒子検出器
US4778657A (en) 1985-09-10 1988-10-18 Kernforschungszentrum Karlsruhe Gmbh Apparatus for determining the characteristics of particles suspended in liquids
US5846708A (en) 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
AU5877600A (en) * 1999-06-22 2001-01-09 Agilent Technologies Inc. Apparatus for the operation of a microfluidic device
US6849423B2 (en) * 2000-11-29 2005-02-01 Picoliter Inc Focused acoustics for detection and sorting of fluid volumes
WO2002059575A2 (en) 2001-01-23 2002-08-01 The Trustees Of Princeton University, Princeton University Method and apparatus for analysis of biological solutions
JP2002286594A (ja) * 2001-03-28 2002-10-03 Olympus Optical Co Ltd 微粒子搬送機構
CN1325658C (zh) 2001-04-23 2007-07-11 三星电子株式会社 包含mosfet分子检测芯片和采用该芯片的分子检测装置以及使用该装置的分子检测方法
AU2002318269A1 (en) * 2001-07-18 2003-03-03 The Regents Of The University Of Michigan Gas-focusing flow cytometer cell and flow cytometer detection system with waveguide optics
EP1421365A1 (en) * 2001-07-19 2004-05-26 Tufts University Optical array device and methods of use thereof for screening, analysis and manipulation of particles
US7179420B2 (en) * 2001-10-25 2007-02-20 Techelan, Llc Apparatus comprising a particle sorter/dispenser and method therefor
CA2480728A1 (en) * 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
BR0309321A (pt) * 2002-04-17 2005-03-29 Cytonome Inc Método e aparelho para selecionar partìculas
WO2005033283A2 (en) 2003-09-30 2005-04-14 Singulex, Inc. Methods for enhancing the analysis of particle detection
US7389879B2 (en) * 2004-01-21 2008-06-24 Hewlett-Packard Development Company, L.P. Sorting particles
CN100582766C (zh) 2004-03-05 2010-01-20 安捷伦科技有限公司 检测通道内剖面缩小的非接触检测单元
US7392908B2 (en) 2005-01-12 2008-07-01 Beckman Coulter, Inc. Methods and apparatus for sorting particles hydraulically
JP4047336B2 (ja) * 2005-02-08 2008-02-13 独立行政法人科学技術振興機構 ゲル電極付セルソーターチップ
EP1855114A1 (en) 2005-03-01 2007-11-14 Rohm Co., Ltd. Microchannel and microfluid chip
CA2607579A1 (en) 2005-05-06 2006-11-23 The Regents Of The University Of California Microfluidic system for identifying or sizing individual particles passing through a channel
WO2007005907A1 (en) * 2005-07-01 2007-01-11 Honeywell International, Inc. A molded cartridge with 3-d hydrodynamic focusing
US20070059683A1 (en) 2005-09-15 2007-03-15 Tom Barber Veterinary diagnostic system
US8290625B2 (en) 2007-04-04 2012-10-16 Beckman Coulter, Inc. Flow cytometer sorter
US8691164B2 (en) * 2007-04-20 2014-04-08 Celula, Inc. Cell sorting system and methods
KR100830221B1 (ko) 2007-04-23 2008-05-16 (주)에이치시티 입자 측정장치
WO2009032827A2 (en) 2007-09-04 2009-03-12 Purdue Research Foundation Electroporative flow cytometry
KR20110030415A (ko) 2008-01-22 2011-03-23 인터젠엑스 인크. 만능 샘플 제조 시스템 및 집적 분석 시스템에서의 용도
US20100099198A1 (en) 2008-07-11 2010-04-22 Board Of Regents, The University Of Texas System Apparatus and system for pattern recognition sensing for biomolecules
ATE544063T1 (de) 2008-07-17 2012-02-15 Koninkl Philips Electronics Nv Nanoporenvorrichtung und verfahren zur nukleinsäureanalyse
JP5382852B2 (ja) 2009-02-06 2014-01-08 株式会社オンチップ・バイオテクノロジーズ 使い捨てチップ型フローセルとそれを用いたフローサイトメーター
JP5487638B2 (ja) * 2009-02-17 2014-05-07 ソニー株式会社 微小粒子分取のための装置及びマイクロチップ
WO2010104993A2 (en) * 2009-03-10 2010-09-16 The Regents Of The University Of California Fluidic flow cytometry devices and particle sensing based on signal-encoding
US9364831B2 (en) 2009-08-08 2016-06-14 The Regents Of The University Of California Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting
US8771933B2 (en) 2009-10-06 2014-07-08 Massachusetts Institute Of Technology Continuous-flow deformability-based cell separation
EP2311975A1 (en) 2009-10-13 2011-04-20 Iee International Electronics & Engineering S.A. Electrophoretic biomolecules separation device
EP3671180B1 (en) * 2010-01-15 2023-03-08 On-chip Biotechnologies Co., Ltd. Method of using an apparatus configured to separate biological particles
US20110293558A1 (en) 2010-03-22 2011-12-01 Massachusetts Institute Of Technology Material properties of t cells and related methods and compositions
US8705031B2 (en) * 2011-02-04 2014-04-22 Cytonome/St, Llc Particle sorting apparatus and method
AU2012243396A1 (en) 2011-04-15 2013-10-31 The University Of British Columbia Method and apparatus for separation of particles
US10466160B2 (en) * 2011-08-01 2019-11-05 Celsee Diagnostics, Inc. System and method for retrieving and analyzing particles
EP2764347B1 (en) 2011-10-06 2022-04-20 The Regents of The University of California Devices for detecting a particle in a sample and methods for use thereof
US8894946B2 (en) * 2011-10-21 2014-11-25 Integenx Inc. Sample preparation, processing and analysis systems
EP2602608B1 (en) * 2011-12-07 2016-09-14 Imec Analysis and sorting of biological cells in flow
US9297784B2 (en) * 2012-12-05 2016-03-29 Caliper Life Sciences, Inc. Device and method for extracting target objects from a sample
JP2016514965A (ja) 2013-03-15 2016-05-26 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 試料中の細胞を分類する装置及び該装置の使用方法
AU2014235403B2 (en) 2013-03-15 2018-06-28 Beckman Coulter, Inc. Optics system for a flow cytometer
CA2895638A1 (en) * 2013-03-15 2014-09-18 Fluidigm Corporation Methods and devices for analysis of defined multicellular combinations
US10343165B2 (en) * 2013-09-05 2019-07-09 Bio-Rad Laboratories, Inc. On-demand particle dispensing system
US8820538B1 (en) 2014-03-17 2014-09-02 Namocell LLC Method and apparatus for particle sorting
CN110038653A (zh) * 2014-05-27 2019-07-23 伊鲁米那股份有限公司 包括基本仪器和可拆卸盒的用于生物化学分析的系统和方法
EP3154693B1 (en) * 2014-06-11 2021-11-03 PerkinElmer Health Sciences, Inc. Method for performing a sample assay with a microfluidic cartridges with integrated assay controls
KR101702745B1 (ko) * 2014-11-13 2017-02-03 인제대학교 산학협력단 단일세포 분리장치 및 방법
GB2531615B (en) * 2015-02-02 2017-11-22 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
WO2016182034A1 (ja) * 2015-05-12 2016-11-17 株式会社オンチップ・バイオテクノロジーズ 単一粒子解析方法およびその解析のためのシステム
JP7130562B2 (ja) 2016-03-17 2022-09-05 ベクトン・ディキンソン・アンド・カンパニー ハイスループット蛍光フローサイトメーターを用いる細胞選別
US10650602B2 (en) 2016-04-15 2020-05-12 Center Of Human-Centered Interaction For Coexistence Apparatus and method for three-dimensional information augmented video see-through display, and rectification apparatus
US10611995B2 (en) 2018-08-15 2020-04-07 Deepcell, Inc. Systems and methods for particle analysis

Similar Documents

Publication Publication Date Title
JP2020508468A5 (https=)
JP4964752B2 (ja) 粒子を選別する方法および装置
US12188858B2 (en) Microfluidic system with combined electrical and optical detection for high accuracy particle sorting and methods thereof
JP2022191270A (ja) システムおよび方法
US9926521B2 (en) Microfluidic particle-analysis systems
US20040072278A1 (en) Microfluidic particle-analysis systems
CN110988373A (zh) 微流体分析的方法、组合物和系统
JP2022037655A5 (https=)
JP2010271168A (ja) 微小粒子測定装置
JP7440905B2 (ja) 粒子の純化方法、単一粒子分注方法、及び細胞クラスター解析方法、並びそれに用いる装置
WO2014145530A1 (en) Aspiration-free well plate apparatus and methods
Sun et al. Low-stress microfluidic density-gradient centrifugation for blood cell sorting
JP7589775B2 (ja) 微小粒子分取装置、細胞治療薬製造装置、微小粒子分取方法、及びプログラム
JP6237806B2 (ja) 微小粒子分取装置
CN110312926B (zh) 分析多个液滴并从中选择特定液滴的方法和相关装置
JP7287399B2 (ja) 微小粒子分取用流路ユニット及び微小粒子分取装置
EP2629072A1 (en) A light detecting system and a flow cytometer including the light detecting system
JP5978715B2 (ja) 微小粒子分取装置及び微小粒子分取装置の制御方法
JP2013250229A (ja) 微小粒子分取用マイクロチップ、該微小粒子分取用マイクロチップが搭載された微小粒子分取装置、並びに微小粒子の分取方法
Tu et al. Microfluidic cell analysis and sorting using photonic forces
Terray et al. Preparative separations using optical chromatography
HK40011201A (en) Method for analyzing and selecting a specific droplet among a plurality of droplets and associated apparatus