JP2020506722A5 - - Google Patents
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- Publication number
- JP2020506722A5 JP2020506722A5 JP2019561348A JP2019561348A JP2020506722A5 JP 2020506722 A5 JP2020506722 A5 JP 2020506722A5 JP 2019561348 A JP2019561348 A JP 2019561348A JP 2019561348 A JP2019561348 A JP 2019561348A JP 2020506722 A5 JP2020506722 A5 JP 2020506722A5
- Authority
- JP
- Japan
- Prior art keywords
- microorganism
- genetically modified
- enzyme
- molecule
- prk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 244000005700 microbiome Species 0.000 claims 21
- 108010080971 phosphoribulokinase Proteins 0.000 claims 15
- 108010003581 Ribulose-bisphosphate carboxylase Proteins 0.000 claims 8
- 108090000790 Enzymes Proteins 0.000 claims 6
- 102000004190 Enzymes Human genes 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 150000003505 terpenes Chemical class 0.000 claims 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 3
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 3
- 102000014701 Transketolase Human genes 0.000 claims 3
- 108010043652 Transketolase Proteins 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 229930182558 Sterol Natural products 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 230000015556 catabolic process Effects 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- 229930003935 flavonoid Natural products 0.000 claims 2
- 150000002215 flavonoids Chemical class 0.000 claims 2
- 235000017173 flavonoids Nutrition 0.000 claims 2
- 150000007524 organic acids Chemical class 0.000 claims 2
- 235000005985 organic acids Nutrition 0.000 claims 2
- 230000001590 oxidative effect Effects 0.000 claims 2
- 230000004108 pentose phosphate pathway Effects 0.000 claims 2
- 229920005862 polyol Polymers 0.000 claims 2
- 150000003077 polyols Chemical class 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 235000018102 proteins Nutrition 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 238000000746 purification Methods 0.000 claims 2
- 150000003432 sterols Chemical class 0.000 claims 2
- 235000003702 sterols Nutrition 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- 235000007586 terpenes Nutrition 0.000 claims 2
- 229940088594 vitamin Drugs 0.000 claims 2
- 229930003231 vitamin Natural products 0.000 claims 2
- 235000013343 vitamin Nutrition 0.000 claims 2
- 239000011782 vitamin Substances 0.000 claims 2
- FNZLKVNUWIIPSJ-UHNVWZDZSA-N D-ribulose 5-phosphate Chemical compound OCC(=O)[C@H](O)[C@H](O)COP(O)(O)=O FNZLKVNUWIIPSJ-UHNVWZDZSA-N 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 101150007158 NQM1 gene Proteins 0.000 claims 1
- FNZLKVNUWIIPSJ-UHFFFAOYSA-N Rbl5P Natural products OCC(=O)C(O)C(O)COP(O)(O)=O FNZLKVNUWIIPSJ-UHFFFAOYSA-N 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 230000036983 biotransformation Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000012261 overproduction Methods 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 101150115276 tal1 gene Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1750696 | 2017-01-27 | ||
| FR1750696A FR3062395B1 (fr) | 2017-01-27 | 2017-01-27 | Microorganisme genetiquement optimise pour la production de molecules d'interet |
| PCT/EP2018/052004 WO2018138288A1 (fr) | 2017-01-27 | 2018-01-26 | Microorganisme génétiquement optimisé pour la production de molécules d'intérêt |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020506722A JP2020506722A (ja) | 2020-03-05 |
| JP2020506722A5 true JP2020506722A5 (enExample) | 2021-02-12 |
Family
ID=59070758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019561348A Pending JP2020506722A (ja) | 2017-01-27 | 2018-01-26 | 目的分子を産生するための遺伝的に最適化された微生物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20190359988A1 (enExample) |
| EP (1) | EP3574082A1 (enExample) |
| JP (1) | JP2020506722A (enExample) |
| KR (1) | KR20190114982A (enExample) |
| CN (1) | CN110475851A (enExample) |
| BR (1) | BR112019015411A2 (enExample) |
| FR (1) | FR3062395B1 (enExample) |
| WO (1) | WO2018138288A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014219510A1 (en) * | 2013-02-22 | 2015-08-27 | Technische Universiteit Delft | Recombinant micro-organism for use in method with increased product yield |
| US11767521B2 (en) * | 2020-02-21 | 2023-09-26 | The Regents Of The University Of California | Genetically modified bacterial cells and methods useful for producing indigoidine |
| CN118956840A (zh) * | 2021-04-19 | 2024-11-15 | 武汉合生科技有限公司 | 获得α-法尼烯以及β-法尼烯的重组微生物及其构建方法 |
| CN115259391B (zh) * | 2022-08-26 | 2023-10-10 | 辽宁中森生物科技有限公司 | 一种污水处理用多元菌藻组合物、复合剂及其应用 |
| CN117210446A (zh) * | 2023-03-21 | 2023-12-12 | 北京蓝晶微生物科技有限公司 | 一种重建卡尔文循环提高异养微生物代谢产物产量的方法 |
| CN117721054B (zh) * | 2023-12-12 | 2025-01-28 | 四川大学 | 一种提高乳酸菌在盐胁迫下生物膜产量的方法 |
| CN119709580A (zh) * | 2025-03-04 | 2025-03-28 | 诸城市浩天药业有限公司 | 一种高效生产d-泛酸的工程菌株及其构建方法与应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG2014012520A (en) * | 2011-07-12 | 2014-06-27 | Scientist Of Fortune Sa | Recombinant microorganism for the production of useful metabolites |
| FR3016371B1 (fr) * | 2014-01-16 | 2018-02-02 | Institut National De La Recherche Agronomique | Levures modifiees pour utiliser le dioxyde de carbone |
-
2017
- 2017-01-27 FR FR1750696A patent/FR3062395B1/fr not_active Expired - Fee Related
-
2018
- 2018-01-26 KR KR1020197022622A patent/KR20190114982A/ko not_active Ceased
- 2018-01-26 EP EP18702646.3A patent/EP3574082A1/fr active Pending
- 2018-01-26 US US16/480,579 patent/US20190359988A1/en not_active Abandoned
- 2018-01-26 BR BR112019015411-6A patent/BR112019015411A2/pt not_active IP Right Cessation
- 2018-01-26 JP JP2019561348A patent/JP2020506722A/ja active Pending
- 2018-01-26 CN CN201880019539.8A patent/CN110475851A/zh active Pending
- 2018-01-26 WO PCT/EP2018/052004 patent/WO2018138288A1/fr not_active Ceased
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