JP2020505938A - エピジェネティックな免疫細胞計数のための改善された方法 - Google Patents

エピジェネティックな免疫細胞計数のための改善された方法 Download PDF

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JP2020505938A
JP2020505938A JP2019542675A JP2019542675A JP2020505938A JP 2020505938 A JP2020505938 A JP 2020505938A JP 2019542675 A JP2019542675 A JP 2019542675A JP 2019542675 A JP2019542675 A JP 2019542675A JP 2020505938 A JP2020505938 A JP 2020505938A
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cells
blood
demethylated
cell
nucleic acid
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オレク，スフェン
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エピオンティス ゲーエムベーハー
エピオンティス ゲーエムベーハー
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019542675A 2017-02-09 2018-02-08 エピジェネティックな免疫細胞計数のための改善された方法 Pending JP2020505938A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17155496.7 2017-02-09
EP17155496.7A EP3360971A1 (en) 2017-02-09 2017-02-09 Improved method for epigenetic immune cell counting
PCT/EP2018/053206 WO2018146209A1 (en) 2017-02-09 2018-02-08 Improved method for epigenetic immune cell counting

Publications (2)

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JP2020505938A true JP2020505938A (ja) 2020-02-27
JP2020505938A5 JP2020505938A5 (https=) 2021-03-18

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JP2019542675A Pending JP2020505938A (ja) 2017-02-09 2018-02-08 エピジェネティックな免疫細胞計数のための改善された方法

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Country Link
US (1) US11319581B2 (https=)
EP (2) EP3360971A1 (https=)
JP (1) JP2020505938A (https=)
CN (1) CN110382713A (https=)
AU (1) AU2018217352A1 (https=)
CA (1) CA3051314A1 (https=)
WO (1) WO2018146209A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102018116353B4 (de) * 2018-07-05 2020-06-10 Epiontis Gmbh Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening
WO2024073508A2 (en) * 2022-09-27 2024-04-04 Guardant Health, Inc. Methods and compositions for quantifying immune cell dna
CN119372296B (zh) * 2024-12-24 2025-06-13 北京致谱医学检验实验室有限公司 基于基因甲基化检测实现人b淋巴细胞计数的试剂盒
CN119372341B (zh) * 2024-12-30 2025-04-11 北京致谱医学检验实验室有限公司 基于基因甲基化检测实现人nk淋巴细胞计数的试剂盒

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012511917A (ja) * 2008-12-16 2012-05-31 エピオンティス ゲーエムベーハー １型の血液細胞成分の同定のためのエピジェネティックマーカー
JP2015509728A (ja) * 2012-03-12 2015-04-02 エピオンティス ゲーエムベーハー Ｃｄ３ｃｄ４陽性ｔリンパ球の同定用のエピジェネティックマーカー
JP2016505243A (ja) * 2012-11-23 2016-02-25 エピオンティス ゲーエムベーハー ＣＤ８＋Ｔリンパ球、特にＣＤ８α及びβＴリンパ球の亜集団の同定用のエピジェネティック法
JP2016515397A (ja) * 2013-04-19 2016-05-30 エピオンティス ゲーエムベーハー 生体サンプルにおける定量的細胞組成を特定する方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130021400A (ko) * 2005-04-15 2013-03-05 에피제노믹스 아게 세포 증식 질환을 분석하기 위한 방법 및 핵산
CN103031372A (zh) * 2012-08-10 2013-04-10 深圳先进技术研究院 Znf545基因甲基化定量检测方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012511917A (ja) * 2008-12-16 2012-05-31 エピオンティス ゲーエムベーハー １型の血液細胞成分の同定のためのエピジェネティックマーカー
JP2015509728A (ja) * 2012-03-12 2015-04-02 エピオンティス ゲーエムベーハー Ｃｄ３ｃｄ４陽性ｔリンパ球の同定用のエピジェネティックマーカー
JP2016505243A (ja) * 2012-11-23 2016-02-25 エピオンティス ゲーエムベーハー ＣＤ８＋Ｔリンパ球、特にＣＤ８α及びβＴリンパ球の亜集団の同定用のエピジェネティック法
JP2016515397A (ja) * 2013-04-19 2016-05-30 エピオンティス ゲーエムベーハー 生体サンプルにおける定量的細胞組成を特定する方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Epigenetic quantification of tumor-infiltrating T-lymphocytes", EPIGENETICS, vol. Volume 6, Issue 2, JPN6021048145, 2011, pages 236 - 246, ISSN: 0004843315 *

Also Published As

Publication number Publication date
WO2018146209A1 (en) 2018-08-16
CA3051314A1 (en) 2018-08-16
CN110382713A (zh) 2019-10-25
US20190390263A1 (en) 2019-12-26
US11319581B2 (en) 2022-05-03
EP3360971A1 (en) 2018-08-15
AU2018217352A1 (en) 2019-08-08
EP3580358A1 (en) 2019-12-18

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