JP2020504754A5 - - Google Patents
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- Publication number
- JP2020504754A5 JP2020504754A5 JP2019535843A JP2019535843A JP2020504754A5 JP 2020504754 A5 JP2020504754 A5 JP 2020504754A5 JP 2019535843 A JP2019535843 A JP 2019535843A JP 2019535843 A JP2019535843 A JP 2019535843A JP 2020504754 A5 JP2020504754 A5 JP 2020504754A5
- Authority
- JP
- Japan
- Prior art keywords
- carboxamide
- group
- amino
- ethyl
- oxoethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- CQUNASYKUVRVAK-UHFFFAOYSA-N CC(CCOCCOCCOCCOCCNC)=O Chemical compound CC(CCOCCOCCOCCOCCNC)=O CQUNASYKUVRVAK-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662439600P | 2016-12-28 | 2016-12-28 | |
| US62/439,600 | 2016-12-28 | ||
| PCT/US2017/068686 WO2018125992A1 (en) | 2016-12-28 | 2017-12-28 | Functionalized nanoluc inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020504754A JP2020504754A (ja) | 2020-02-13 |
| JP2020504754A5 true JP2020504754A5 (https=) | 2021-02-12 |
| JP7161475B2 JP7161475B2 (ja) | 2022-10-26 |
Family
ID=61007855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019535843A Active JP7161475B2 (ja) | 2016-12-28 | 2017-12-28 | 官能化ｎａｎｏｌｕｃ阻害剤 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10815247B2 (https=) |
| EP (1) | EP3562823B1 (https=) |
| JP (1) | JP7161475B2 (https=) |
| WO (1) | WO2018125992A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016210294A1 (en) | 2015-06-25 | 2016-12-29 | Promega Corporation | Thienopyrrole compounds and uses thereof as inhibitors of oplophorus-derived luciferases |
| WO2018125992A1 (en) | 2016-12-28 | 2018-07-05 | Promega Corporation | Functionalized nanoluc inhibitors |
| US12180581B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US12181452B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
| US11709155B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| EP3802514B1 (en) * | 2018-06-01 | 2022-08-03 | Promega Corporation | Inhibitors of oplophorus luciferase-derived bioluminescent complexes |
| WO2020041579A1 (en) | 2018-08-23 | 2020-02-27 | Promega Corporation | Coelenterazine analogues |
| SG11202101085PA (en) | 2018-08-27 | 2021-03-30 | Sumitomo Dainippon Pharma Co Ltd | Optically active azabicyclic derivative |
| CN111848657B (zh) * | 2019-04-24 | 2021-12-31 | 中国科学院上海药物研究所 | 靶向酪氨酸激酶识别的可逆性荧光化合物及其制备方法和应用 |
| US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
| US12352734B2 (en) | 2020-09-24 | 2025-07-08 | Waters Technologies Corporation | Chromatographic hardware improvements for separation of reactive molecules |
| KR20250085812A (ko) | 2022-10-14 | 2025-06-12 | 프로메가 코포레이션 | 코엘렌테라진 유사체 |
| US20250206747A1 (en) | 2023-12-20 | 2025-06-26 | Promega Corporation | Coelenterazine analogues |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3828535A1 (de) | 1988-08-23 | 1990-03-08 | Basf Ag | Benzimidazol-2-carbonsaeureanilide, ihre verwendung als lichtschutzmittel fuer organisches material und mit diesen aniliden stabilisiertes organisches material |
| US5283179A (en) | 1990-09-10 | 1994-02-01 | Promega Corporation | Luciferase assay method |
| DK0746544T3 (da) * | 1994-02-22 | 1999-06-07 | Merrell Pharma Inc | Indolderivater til behandling af østrogenafhængige neoplasmer og sygdomme |
| US7268229B2 (en) | 2001-11-02 | 2007-09-11 | Promega Corporation | Compounds to co-localize luminophores with luminescent proteins |
| EP1314733A1 (en) | 2001-11-22 | 2003-05-28 | Aventis Pharma Deutschland GmbH | Indole-2-carboxamides as factor Xa inhibitors |
| EP1753428A4 (en) | 2004-05-14 | 2010-09-15 | Abbott Lab | INHIBITORS OF KINASES AS THERAPEUTIC AGENTS |
| FR2897061B1 (fr) | 2006-02-03 | 2010-09-03 | Sanofi Aventis | Derives de n-heteroaryl-carboxamides tricycliques contenant un motif benzimidazole, leur preparation et leur application en therapeutique. |
| WO2008118445A1 (en) | 2007-03-26 | 2008-10-02 | Promega Corporation | Methods to quench light from optical reactions |
| US8163910B2 (en) | 2007-10-03 | 2012-04-24 | Elitech Holding B.V. | Amide-substituted xanthene dyes |
| WO2010051048A1 (en) * | 2008-02-20 | 2010-05-06 | The Wistar Institute | Microrna modulators and method for identifying and using the same |
| WO2010118208A1 (en) | 2009-04-09 | 2010-10-14 | Exelixis, Inc. | Benzoxazepin-4- (5h) -yl derivatives and their use to treat cancer |
| ES2795287T3 (es) | 2009-05-01 | 2020-11-23 | Promega Corp | Luciferasas de Oplophorus sintéticas con mayor emisión de luz |
| US20130178453A1 (en) | 2010-02-09 | 2013-07-11 | Ironwood Pharmaceuticals, Inc. | Cannabinoid Agonists |
| SG10202103336SA (en) | 2010-11-02 | 2021-04-29 | Promega Corp | Novel coelenterazine substrates and methods of use |
| CN103180324A (zh) | 2010-11-02 | 2013-06-26 | 普罗美加公司 | 腔肠素衍生物及其使用方法 |
| JP6067019B2 (ja) | 2011-09-02 | 2017-01-25 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | 代謝的に活性な細胞の酸化還元状態を評価するための化合物及び方法、ならびにｎａｄ（ｐ）／ｎａｄ（ｐ）ｈを測定するための方法 |
| US20140099654A1 (en) | 2012-09-26 | 2014-04-10 | Promega Corporation | Real-time monitoring |
| WO2015067302A1 (en) | 2013-11-05 | 2015-05-14 | Ecole Polytechnique Federale De Lausanne (Epfl) | Sensor molecules and uses thereof |
| EP3099691B1 (en) | 2014-01-29 | 2019-11-20 | Promega Corporation | Pro-substrates for live cell applications |
| US9790537B2 (en) * | 2014-01-29 | 2017-10-17 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| EP3304078B1 (en) | 2015-06-05 | 2022-08-31 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
| WO2016210294A1 (en) * | 2015-06-25 | 2016-12-29 | Promega Corporation | Thienopyrrole compounds and uses thereof as inhibitors of oplophorus-derived luciferases |
| WO2018125992A1 (en) | 2016-12-28 | 2018-07-05 | Promega Corporation | Functionalized nanoluc inhibitors |
-
2017
- 2017-12-28 WO PCT/US2017/068686 patent/WO2018125992A1/en not_active Ceased
- 2017-12-28 US US15/856,302 patent/US10815247B2/en active Active
- 2017-12-28 EP EP17832700.3A patent/EP3562823B1/en active Active
- 2017-12-28 JP JP2019535843A patent/JP7161475B2/ja active Active
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