|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
GB1512203A
(en)
|
1974-05-08 |
1978-05-24 |
Aspin F |
Rolls for use in profiling film
|
|
CA1186621A
(en)
|
1981-08-10 |
1985-05-07 |
John L. Hendrix |
Fluoro immuno assay system
|
|
JPS5896026A
(ja)
|
1981-10-30 |
1983-06-07 |
Nippon Chemiphar Co Ltd |
新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤
|
|
DE3380726D1
(en)
|
1982-06-24 |
1989-11-23 |
Japan Chem Res |
Long-acting composition
|
|
US4681581A
(en)
|
1983-12-05 |
1987-07-21 |
Coates Fredrica V |
Adjustable size diaper and folding method therefor
|
|
FR2570703B1
(fr)
|
1984-09-26 |
1988-07-08 |
Commissariat Energie Atomique |
Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
|
|
US4766106A
(en)
|
1985-06-26 |
1988-08-23 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polymer conjugation
|
|
US4735210A
(en)
|
1985-07-05 |
1988-04-05 |
Immunomedics, Inc. |
Lymphographic and organ imaging method and kit
|
|
US5101827A
(en)
|
1985-07-05 |
1992-04-07 |
Immunomedics, Inc. |
Lymphographic and organ imaging method and kit
|
|
US5776093A
(en)
|
1985-07-05 |
1998-07-07 |
Immunomedics, Inc. |
Method for imaging and treating organs and tissues
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
WO1988004777A1
(en)
|
1986-12-15 |
1988-06-30 |
Ultra Diagnostics Corporation |
Monomeric phthalocyanine reagents
|
|
US5750172A
(en)
|
1987-06-23 |
1998-05-12 |
Pharming B.V. |
Transgenic non human mammal milk
|
|
US4876190A
(en)
|
1987-10-21 |
1989-10-24 |
Becton Dickinson & Company |
Peridinin-chlorophyll complex as fluorescent label
|
|
US5648471A
(en)
|
1987-12-03 |
1997-07-15 |
Centocor, Inc. |
One vial method for labeling antibodies with Technetium-99m
|
|
FR2624862B1
(fr)
|
1987-12-18 |
1990-06-08 |
Oris Ind |
Cryptates de terres rares, procedes d'obtention, intermediaires de synthese et application a titre de marqueurs fluorescents
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
DK0486622T3
(da)
|
1989-08-09 |
1999-07-19 |
Rhomed Inc |
Direkte radiomærkning af antistoffer og andre proteiner med technetium eller rhenium
|
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
ATE158021T1
(de)
|
1990-08-29 |
1997-09-15 |
Genpharm Int |
Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
|
WO1992022645A1
(en)
|
1991-06-14 |
1992-12-23 |
Genpharm International, Inc. |
Transgenic immunodeficient non-human animals
|
|
CA2113113A1
(en)
|
1991-07-08 |
1993-01-21 |
Simon W. Kantor |
Thermotropic liquid crystal segmented block copolymer
|
|
WO1994019935A1
(en)
|
1993-03-09 |
1994-09-15 |
Genzyme Corporation |
Isolation of components of interest from milk
|
|
JPH08509612A
(ja)
|
1993-04-26 |
1996-10-15 |
ジェンファーム インターナショナル インコーポレイテッド |
異種抗体を産生することができるトランスジェニック非ヒト動物
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US6077835A
(en)
|
1994-03-23 |
2000-06-20 |
Case Western Reserve University |
Delivery of compacted nucleic acid to cells
|
|
KR970029803A
(ko)
|
1995-11-03 |
1997-06-26 |
김광호 |
반도체 메모리장치의 프리차지 회로
|
|
DK1034298T3
(da)
|
1997-12-05 |
2012-01-30 |
Scripps Research Inst |
Humanisering af murint antistof
|
|
WO2000046147A2
(en)
|
1999-02-03 |
2000-08-10 |
Biosante Pharmaceuticals, Inc. |
Therapeutic calcium phosphate particles and methods of manufacture and use
|
|
US6281005B1
(en)
|
1999-05-14 |
2001-08-28 |
Copernicus Therapeutics, Inc. |
Automated nucleic acid compaction device
|
|
MXPA02000962A
(es)
|
1999-07-29 |
2002-07-02 |
Medarex Inc |
Anticuerpos monoclonales humanos para her2/neu.
|
|
EP1212422B1
(en)
|
1999-08-24 |
2007-02-21 |
Medarex, Inc. |
Human ctla-4 antibodies and their uses
|
|
WO2002004482A1
(en)
|
2000-07-07 |
2002-01-17 |
Panacea Pharmaceuticals, Inc. |
Methods for preventing neural tissue damage and for the treatment of alpha-synuclein diseases
|
|
CA2430013C
(en)
|
2000-11-30 |
2011-11-22 |
Medarex, Inc. |
Transgenic transchromosomal rodents for making human antibodies
|
|
WO2003000714A2
(en)
|
2001-06-22 |
2003-01-03 |
Panacea Pharmaceuticals, Inc. |
Compositions and methods for preventing protein aggregation in neurodegenerative diseases
|
|
MXPA05000511A
(es)
|
2001-07-12 |
2005-09-30 |
Jefferson Foote |
Anticuepros super humanizados.
|
|
US8829198B2
(en)
|
2007-10-31 |
2014-09-09 |
Proteotech Inc |
Compounds, compositions and methods for the treatment of beta-amyloid diseases and synucleinopathies
|
|
US9034337B2
(en)
|
2003-10-31 |
2015-05-19 |
Prothena Biosciences Limited |
Treatment and delay of outset of synucleinopathic and amyloidogenic disease
|
|
US20080014194A1
(en)
|
2003-10-31 |
2008-01-17 |
Elan Pharmaceuticals, Inc. |
Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
|
|
TW200509968A
(en)
|
2002-11-01 |
2005-03-16 |
Elan Pharm Inc |
Prevention and treatment of synucleinopathic disease
|
|
US8506959B2
(en)
|
2002-11-01 |
2013-08-13 |
Neotope Biosciences Limited |
Prevention and treatment of synucleinopathic and amyloidogenic disease
|
|
US7358331B2
(en)
|
2003-05-19 |
2008-04-15 |
Elan Pharmaceuticals, Inc. |
Truncated fragments of alpha-synuclein in Lewy body disease
|
|
PL2361928T3
(pl)
|
2003-05-19 |
2017-09-29 |
Prothena Biosciences Limited |
Skrócone fragmenty alfa-synukleiny w chorobie z ciałami Lewy'ego
|
|
WO2005047860A2
(en)
|
2003-11-08 |
2005-05-26 |
Elan Pharmaceuticals, Inc. |
Antibodies to alpha-synuclein
|
|
EP1740615B1
(en)
|
2004-03-31 |
2014-11-05 |
Genentech, Inc. |
Humanized anti-tgf-beta antibodies
|
|
JP2006031250A
(ja)
|
2004-07-14 |
2006-02-02 |
Fuji Xerox Co Ltd |
通信装置およびその制御方法
|
|
EA013752B1
(ru)
|
2004-08-09 |
2010-06-30 |
Элан Фармасьютикалз, Инк. |
Предупреждение и лечение синуклеинопатических и амилоидогенных заболеваний
|
|
US20060205024A1
(en)
|
2005-03-08 |
2006-09-14 |
Sun Health Research Institute |
Method to diagnose and evaluate progression of Alzheimer's disease
|
|
WO2007011907A2
(en)
|
2005-07-19 |
2007-01-25 |
University Of Rochester |
Alpha-synuclein antibodies and methods related thereto
|
|
WO2007021255A1
(en)
|
2005-08-09 |
2007-02-22 |
Elan Pharmaceuticals, Inc. |
Antibodies to alpha-synuclein
|
|
CA2631184A1
(en)
|
2005-11-28 |
2007-05-31 |
Genmab A/S |
Recombinant monovalent antibodies and methods for production thereof
|
|
HUE043966T2
(hu)
|
2007-02-23 |
2019-09-30 |
Prothena Biosciences Ltd |
Szinukleinopátiás és amiloidogén betegség megelõzése és kezelése
|
|
PL2583978T3
(pl)
|
2007-02-23 |
2016-07-29 |
Prothena Biosciences Ltd Co |
Profilaktyka i leczenie chorób synukleinopatycznych i amyloidogennych
|
|
JP5588866B2
(ja)
|
2007-08-10 |
2014-09-10 |
メダレックス エル．エル．シー． |
Ｈｃｏ３２およびｈｃｏ２７、ならびに関連実施例
|
|
PT2282758T
(pt)
|
2008-04-29 |
2019-02-12 |
Bioarctic Ab |
Anticorpos e vacinas para uso em métodos terapêuticos e diagnósticos para perturbações relacionadas com a alfa-sinucleína
|
|
CN102317316B
(zh)
|
2008-12-19 |
2014-08-13 |
帕尼玛制药股份公司 |
人抗α突触核蛋白自身抗体
|
|
JP5894939B2
(ja)
|
2010-02-26 |
2016-03-30 |
バイオアークティック ニューロサイエンス アーベー |
プロトフィブリル結合抗体ならびにパーキンソン病、レビー小体型認知症および他のα−シヌクレイノパチーの治療および診断方法におけるこれらの使用
|
|
EP2366714A1
(en)
|
2010-03-03 |
2011-09-21 |
Dr. Rentschler Holding GmbH & Co. KG |
Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein
|
|
GB201008682D0
(en)
*
|
2010-05-25 |
2010-07-07 |
Vib Vzw |
Epitope tag for affinity based applications
|
|
JP2014502356A
(ja)
|
2010-11-24 |
2014-01-30 |
エラン ファーマシューティカルズ，インコーポレイテッド |
シヌクレイン病のマーカーとしての食作用活性
|
|
KR101308898B1
(ko)
*
|
2011-02-08 |
2013-09-23 |
건국대학교 산학협력단 |
신규 항-α-시누클레인 단일클론항체 및 이를 이용한 ＥＬＩＳＡ 시스템
|
|
SI2723379T1
(sl)
|
2011-06-23 |
2019-03-29 |
Biogen International Neuroscience Gmbh |
Molekule, ki se vežejo ma anti alfa-sinuklein
|
|
JP2013059866A
(ja)
|
2011-09-12 |
2013-04-04 |
Seiko Epson Corp |
液体噴射装置、液体噴射装置の制御方法および液体噴射装置の制御プログラム
|
|
RS63930B1
(sr)
|
2011-10-28 |
2023-02-28 |
Prothena Biosciences Ltd |
Humanizovana antitela koja prepoznaju alfa-sinuklein
|
|
SG10201708959WA
(en)
|
2012-07-03 |
2017-11-29 |
Univ Washington |
Antibodies to tau
|
|
UA118441C2
(uk)
*
|
2012-10-08 |
2019-01-25 |
Протена Біосаєнсиз Лімітед |
Антитіло, що розпізнає альфа-синуклеїн
|
|
US9534044B2
(en)
|
2013-02-28 |
2017-01-03 |
United Arab Emirates University |
Alpha-synuclein antibodies and uses thereof
|
|
US10513555B2
(en)
|
2013-07-04 |
2019-12-24 |
Prothena Biosciences Limited |
Antibody formulations and methods
|
|
LT3071597T
(lt)
|
2013-11-21 |
2020-10-12 |
F. Hoffmann-La Roche Ag |
Antikūnai prieš alfa-sunukleiną ir jų naudojimo būdai
|
|
JP2017536102A
(ja)
|
2014-10-16 |
2017-12-07 |
ジェネンテック， インコーポレイテッド |
抗アルファ−シヌクレイン抗体及び使用方法
|
|
GB201512203D0
(en)
|
2015-07-13 |
2015-08-19 |
Lundbeck & Co As H |
Agents,uses and methods
|
|
EP3341725B1
(en)
|
2015-08-25 |
2021-08-18 |
Prothena Biosciences Limited |
Methods for detecting phosphorylated alpha-synuclein
|
|
US10160800B2
(en)
|
2016-06-02 |
2018-12-25 |
Medimmune Limited |
Antibodies to α-synuclein and uses thereof
|
|
BR112018014281A2
(pt)
|
2016-11-15 |
2018-12-18 |
H Lundbeck As |
agentes, usos e métodos para o tratamento da sinucleinopatia
|
|
US10364286B2
(en)
|
2016-12-22 |
2019-07-30 |
H. Lundbeck A/S |
Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation
|
|
CN111630382A
(zh)
|
2017-12-21 |
2020-09-04 |
H.隆德贝克有限公司 |
α-共核蛋白病的测定、方法和治疗
|