JP2020503013A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020503013A5 JP2020503013A5 JP2019531740A JP2019531740A JP2020503013A5 JP 2020503013 A5 JP2020503013 A5 JP 2020503013A5 JP 2019531740 A JP2019531740 A JP 2019531740A JP 2019531740 A JP2019531740 A JP 2019531740A JP 2020503013 A5 JP2020503013 A5 JP 2020503013A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- seq
- composition according
- antibody
- adm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023009286A JP7892568B2 (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン(ADM)抗体、または抗ADM抗体フラグメント、または抗ADM非Ig足場 |
| JP2024143320A JP2024170454A (ja) | 2016-12-16 | 2024-08-23 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン(ADM)抗体、または抗ADM抗体フラグメント、または抗ADM非Ig足場 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16204847.4 | 2016-12-16 | ||
| EP16204847 | 2016-12-16 | ||
| EP16206305.1A EP3339324A1 (en) | 2016-12-22 | 2016-12-22 | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in intervention and therapy of congestion in a patient in need thereof |
| EP16206305.1 | 2016-12-22 | ||
| EP17197176 | 2017-10-18 | ||
| EP17197176.5 | 2017-10-18 | ||
| PCT/EP2017/083311 WO2018109228A1 (en) | 2016-12-16 | 2017-12-18 | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in intervention and therapy of congestion in a patient in need thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009286A Division JP7892568B2 (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン(ADM)抗体、または抗ADM抗体フラグメント、または抗ADM非Ig足場 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020503013A JP2020503013A (ja) | 2020-01-30 |
| JP2020503013A5 true JP2020503013A5 (enExample) | 2021-02-04 |
| JP7727371B2 JP7727371B2 (ja) | 2025-08-21 |
Family
ID=61148166
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019531740A Active JP7727371B2 (ja) | 2016-12-16 | 2017-12-18 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン(ADM)抗体、または抗ADM抗体フラグメント、または抗ADM非Ig足場 |
| JP2023009286A Active JP7892568B2 (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン(ADM)抗体、または抗ADM抗体フラグメント、または抗ADM非Ig足場 |
| JP2024143320A Pending JP2024170454A (ja) | 2016-12-16 | 2024-08-23 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン(ADM)抗体、または抗ADM抗体フラグメント、または抗ADM非Ig足場 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009286A Active JP7892568B2 (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン(ADM)抗体、または抗ADM抗体フラグメント、または抗ADM非Ig足場 |
| JP2024143320A Pending JP2024170454A (ja) | 2016-12-16 | 2024-08-23 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン(ADM)抗体、または抗ADM抗体フラグメント、または抗ADM非Ig足場 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20200299372A1 (enExample) |
| EP (1) | EP3555130A1 (enExample) |
| JP (3) | JP7727371B2 (enExample) |
| KR (3) | KR20190120174A (enExample) |
| CN (2) | CN110167962B (enExample) |
| AU (2) | AU2017375049B2 (enExample) |
| BR (1) | BR112019011713A2 (enExample) |
| CA (1) | CA3046850A1 (enExample) |
| IL (2) | IL322765A (enExample) |
| MX (1) | MX2019007107A (enExample) |
| MY (1) | MY208219A (enExample) |
| RU (1) | RU2762059C2 (enExample) |
| WO (1) | WO2018109228A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220227854A1 (en) * | 2017-09-25 | 2022-07-21 | Adrenomed Ag | Anti-adrenomedullin (adm) binder for use in therapy or prevention of symptoms of illness |
| EP3871689A1 (en) * | 2020-02-26 | 2021-09-01 | sphingotec GmbH | Anti-adm-antibodies binding to the free n-terminus for accelerated transition of adm-gly to bio-adm in patients with adm-gly/ bio-adm ratio above a threshold and combination with vitamin c |
| CA3168978A1 (en) * | 2020-02-27 | 2021-09-02 | Andreas Bergmann | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy or prevention of shock |
| US20210285949A1 (en) * | 2020-03-16 | 2021-09-16 | Sphingotec Gmbh | Pro-adrenomedullin or fragment thereof in patients infected with corona virus and treatments with binder against adrenomedullin |
| CN119072492A (zh) | 2022-03-15 | 2024-12-03 | 艾德里诺医药公司 | 抗肾上腺髓质素(adm)抗体或抗adm抗体片段的稳定水性制剂 |
| KR20250040987A (ko) * | 2022-07-20 | 2025-03-25 | 상하이 제유 파마슈티칼 컴퍼니 리미티드 | 항-아드레노메둘린 비중화 항체, 이의 제조 방법 및 응용 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| AU634716B2 (en) | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP1690935A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| ES2139598T3 (es) | 1990-07-10 | 2000-02-16 | Medical Res Council | Procedimientos para la produccion de miembros de parejas de union especifica. |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| JPH07503132A (ja) | 1991-12-17 | 1995-04-06 | ジェンファーム インターナショナル,インコーポレイティド | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| JP2774769B2 (ja) | 1993-04-26 | 1998-07-09 | 賢治 寒川 | アドレノメデュリン |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| CN1628126A (zh) | 2001-08-30 | 2005-06-15 | 比奥雷克西斯药物公司 | 经修饰的运铁蛋白融合蛋白 |
| PT2298278E (pt) | 2002-06-07 | 2016-02-25 | Dyax Corp | Prevenção e redução da perda de sangue e resposta inflamatória |
| DE10316583A1 (de) | 2003-04-10 | 2004-10-28 | B.R.A.H.M.S Aktiengesellschaft | Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung |
| WO2004097423A1 (en) | 2003-04-25 | 2004-11-11 | Genova Ltd. | Secreted polypeptide species reduced cardiovascular disorders |
| CA2543360A1 (en) | 2003-10-24 | 2005-05-06 | Joost A. Kolkman | Ldl receptor class a and egf domain monomers and multimers |
| US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| US20070280886A1 (en) | 2004-09-09 | 2007-12-06 | Bayer Healthcare Ag | Diagnostics and Therapeutics for Diseases Associated with Adrenomedullin Receptor (Amdr) |
| AU2005287557B2 (en) | 2004-09-21 | 2011-10-13 | Biontech Ag | Use of microproteins as tryptase inhibitors |
| ES2373832T3 (es) | 2007-12-19 | 2012-02-09 | Affibody Ab | Polipéptido derivado de proteína a y capaz de unirse a pdgf. |
| EP2324059A4 (en) * | 2008-07-01 | 2012-12-05 | Cephalon Australia Vic Pty Ltd | THERAPEUTIC ANTI-PAMP ANTIBODIES |
| NZ592591A (en) | 2008-11-03 | 2012-04-27 | Molecular Partners Ag | Binding proteins comprising ankyrin repeast domains that inhibit the vegf-a receptor interaction |
| CA2772162C (en) | 2009-08-27 | 2018-05-22 | Covagen Ag | Anti-il-17a fynomers and medical uses thereof |
| BR112012014417B1 (pt) | 2009-12-14 | 2021-11-09 | Scil Proteins Gmbh | Proteínas ubiquitinas modificadas tendo uma atividade de ligação específica para o extradomínio b de fibronectina |
| AU2011263786B2 (en) | 2010-06-08 | 2014-11-13 | Astrazeneca Ab | Tear lipocalin muteins binding IL-4 R alpha |
| BR112012032389A2 (pt) * | 2010-06-18 | 2016-10-25 | Brahms Gmbh | biomarcadores para a previsão de câncer incidente |
| HRP20190122T1 (hr) | 2011-11-16 | 2019-03-08 | Adrenomed Ag | Protutijelo protiv adrenomedulina (adm) ili fragment protutijela protiv adm ili okosnica ne-ig protiv adm, namijenjeni reguliranju ravnoteže tekućina kod pacijenta s kroničnom ili akutnom bolešću |
| PL3553084T3 (pl) * | 2011-11-16 | 2023-04-17 | Adrenomed Ag | Przeciwciało przeciwko adrenomedulinie (adm) lub fragment przeciwciała przeciwko adm lub szkielet przeciwko adm inny niż ig do profilaktyki lub zmniejszania zaburzenia czynności narządu lub niewydolności narządu u pacjenta cierpiącego na przewlekłą lub ostrą chorobę lub ostry stan |
| BR112014011670B1 (pt) * | 2011-11-16 | 2021-05-25 | Adrenomed Ag | anticorpo anti-adrenomedulina (adm) ou fragmento de anticorpo anti-adm ou um arcabouço de proteína não-igg anti-adm que se liga à adrenomedulina e formulação farmacêutica |
| HRP20191771T1 (hr) * | 2011-11-16 | 2019-12-27 | Adrenomed Ag | Anti-adrenomedulin (adm) antitijelo ili fragment anti-adm antitijela ili anti-adm non-ig skela za uporabu u terapiji akutne bolesti ili akutnog stanja pacijenta za stabiliziranje cirkulacije |
| US9140696B2 (en) * | 2011-11-16 | 2015-09-22 | Adrenomed Ag | Anti-adrenomedullin (ADM) antibody or anti-ADM antibody fragment or anti-ADM non-IG scaffold for reducing the risk of mortality in a patient having a chronic or acute disease or acute condition |
| ES2494190T3 (es) * | 2011-11-16 | 2014-09-15 | Adrenomed Ag | Anticuerpo anti-adrenomedulina (ADM) o fragmento de anticuerpo anti-ADM o andamiaje proteico sin Ig anti-ADM para reducir el riesgo de mortalidad en un paciente que padece una enfermedad crónica o aguda o un estado agudo |
-
2017
- 2017-12-18 KR KR1020197020162A patent/KR20190120174A/ko not_active Ceased
- 2017-12-18 EP EP17837953.3A patent/EP3555130A1/en active Pending
- 2017-12-18 WO PCT/EP2017/083311 patent/WO2018109228A1/en not_active Ceased
- 2017-12-18 IL IL322765A patent/IL322765A/en unknown
- 2017-12-18 CA CA3046850A patent/CA3046850A1/en active Pending
- 2017-12-18 RU RU2019122135A patent/RU2762059C2/ru active
- 2017-12-18 CN CN201780077335.5A patent/CN110167962B/zh active Active
- 2017-12-18 AU AU2017375049A patent/AU2017375049B2/en active Active
- 2017-12-18 BR BR112019011713-0A patent/BR112019011713A2/pt unknown
- 2017-12-18 KR KR1020257017044A patent/KR20250084231A/ko active Pending
- 2017-12-18 KR KR1020247006366A patent/KR20240033285A/ko not_active Ceased
- 2017-12-18 MY MYPI2019003407A patent/MY208219A/en unknown
- 2017-12-18 CN CN202410627213.0A patent/CN118767128A/zh active Pending
- 2017-12-18 MX MX2019007107A patent/MX2019007107A/es unknown
- 2017-12-18 JP JP2019531740A patent/JP7727371B2/ja active Active
- 2017-12-18 US US16/469,738 patent/US20200299372A1/en not_active Abandoned
-
2019
- 2019-06-12 IL IL267282A patent/IL267282A/en unknown
-
2021
- 2021-06-04 US US17/339,221 patent/US20220041703A1/en active Pending
-
2023
- 2023-01-25 JP JP2023009286A patent/JP7892568B2/ja active Active
-
2024
- 2024-08-23 JP JP2024143320A patent/JP2024170454A/ja active Pending
-
2025
- 2025-04-29 AU AU2025202983A patent/AU2025202983A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023052614A5 (enExample) | ||
| JP2022105138A5 (enExample) | ||
| JP2016529229A5 (enExample) | ||
| JP2020506693A5 (enExample) | ||
| JP2021505156A5 (enExample) | ||
| JP6640083B2 (ja) | 肺高血圧症を治療するための組成物および方法 | |
| JP2019535763A5 (enExample) | ||
| JP2015522576A5 (enExample) | ||
| JP2023505492A5 (enExample) | ||
| JP2022502367A5 (enExample) | ||
| JP2019510739A5 (enExample) | ||
| JP2010521147A5 (enExample) | ||
| JP2018508489A5 (enExample) | ||
| JP2018500924A5 (enExample) | ||
| JP2018530331A5 (enExample) | ||
| JP2017113019A5 (enExample) | ||
| JP2019536806A5 (enExample) | ||
| JP2014221801A5 (enExample) | ||
| RU2019122135A (ru) | Антитело против адреномедуллина (adm) или фрагмент анти-adm антитела, или анти-adm не-ig каркас для применения при вмешательстве и терапии гиперемии у пациента | |
| JP2019506841A5 (enExample) | ||
| JP2018537966A5 (enExample) | ||
| JP2017529067A5 (enExample) | ||
| JP2020517628A5 (enExample) | ||
| JP2023534143A5 (enExample) | ||
| JP2019528285A5 (enExample) |