JP2020503013A5 - - Google Patents
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- JP2020503013A5 JP2020503013A5 JP2019531740A JP2019531740A JP2020503013A5 JP 2020503013 A5 JP2020503013 A5 JP 2020503013A5 JP 2019531740 A JP2019531740 A JP 2019531740A JP 2019531740 A JP2019531740 A JP 2019531740A JP 2020503013 A5 JP2020503013 A5 JP 2020503013A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- seq
- composition according
- antibody
- adm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023009286A JP2023052614A (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
| JP2024143320A JP2024170454A (ja) | 2016-12-16 | 2024-08-23 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16204847.4 | 2016-12-16 | ||
| EP16204847 | 2016-12-16 | ||
| EP16206305.1A EP3339324A1 (en) | 2016-12-22 | 2016-12-22 | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in intervention and therapy of congestion in a patient in need thereof |
| EP16206305.1 | 2016-12-22 | ||
| EP17197176.5 | 2017-10-18 | ||
| EP17197176 | 2017-10-18 | ||
| PCT/EP2017/083311 WO2018109228A1 (en) | 2016-12-16 | 2017-12-18 | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in intervention and therapy of congestion in a patient in need thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009286A Division JP2023052614A (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020503013A JP2020503013A (ja) | 2020-01-30 |
| JP2020503013A5 true JP2020503013A5 (enExample) | 2021-02-04 |
| JP7727371B2 JP7727371B2 (ja) | 2025-08-21 |
Family
ID=61148166
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019531740A Active JP7727371B2 (ja) | 2016-12-16 | 2017-12-18 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
| JP2023009286A Pending JP2023052614A (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
| JP2024143320A Pending JP2024170454A (ja) | 2016-12-16 | 2024-08-23 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009286A Pending JP2023052614A (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
| JP2024143320A Pending JP2024170454A (ja) | 2016-12-16 | 2024-08-23 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20200299372A1 (enExample) |
| EP (1) | EP3555130A1 (enExample) |
| JP (3) | JP7727371B2 (enExample) |
| KR (3) | KR20250084231A (enExample) |
| CN (2) | CN110167962B (enExample) |
| AU (2) | AU2017375049B2 (enExample) |
| BR (1) | BR112019011713A2 (enExample) |
| CA (1) | CA3046850A1 (enExample) |
| IL (2) | IL322765A (enExample) |
| MX (1) | MX2019007107A (enExample) |
| MY (1) | MY208219A (enExample) |
| RU (2) | RU2021135712A (enExample) |
| WO (1) | WO2018109228A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119215164A (zh) * | 2017-09-25 | 2024-12-31 | 艾德里诺医药公司 | 用于治疗或预防疾病症状的抗肾上腺髓质素（adm）结合剂 |
| EP3871689A1 (en) * | 2020-02-26 | 2021-09-01 | sphingotec GmbH | Anti-adm-antibodies binding to the free n-terminus for accelerated transition of adm-gly to bio-adm in patients with adm-gly/ bio-adm ratio above a threshold and combination with vitamin c |
| CA3168978A1 (en) * | 2020-02-27 | 2021-09-02 | Andreas Bergmann | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy or prevention of shock |
| EP4121771A1 (en) * | 2020-03-16 | 2023-01-25 | AdrenoMed AG | Pro-adrenomedullin or fragment thereof in patients infected with corona virus and treatments with binder against adrenomedullin |
| CN119072492A (zh) | 2022-03-15 | 2024-12-03 | 艾德里诺医药公司 | 抗肾上腺髓质素（adm）抗体或抗adm抗体片段的稳定水性制剂 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| AU634716B2 (en) | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ATE356869T1 (de) | 1990-01-12 | 2007-04-15 | Amgen Fremont Inc | Bildung von xenogenen antikörpern |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| ES2139598T3 (es) | 1990-07-10 | 2000-02-16 | Medical Res Council | Procedimientos para la produccion de miembros de parejas de union especifica. |
| WO1993012227A1 (en) | 1991-12-17 | 1993-06-24 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| JP2774769B2 (ja) | 1993-04-26 | 1998-07-09 | 賢治 寒川 | アドレノメデュリン |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| CN1628126A (zh) | 2001-08-30 | 2005-06-15 | 比奥雷克西斯药物公司 | 经修饰的运铁蛋白融合蛋白 |
| ATE477020T1 (de) | 2002-06-07 | 2010-08-15 | Dyax Corp | Prevention und verringerung von ischemia |
| DE10316583A1 (de) | 2003-04-10 | 2004-10-28 | B.R.A.H.M.S Aktiengesellschaft | Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung |
| JP2007523844A (ja) | 2003-04-25 | 2007-08-23 | ジェノバ・リミテッド | 心臓血管障害において減少する分泌ポリペプチド種 |
| CA2543360A1 (en) | 2003-10-24 | 2005-05-06 | Joost A. Kolkman | Ldl receptor class a and egf domain monomers and multimers |
| US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| WO2006027147A2 (en) | 2004-09-09 | 2006-03-16 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with adrenomedullin receptor (amdr) |
| AU2005287557B2 (en) | 2004-09-21 | 2011-10-13 | Biontech Ag | Use of microproteins as tryptase inhibitors |
| ES2373832T3 (es) | 2007-12-19 | 2012-02-09 | Affibody Ab | Polipéptido derivado de proteína a y capaz de unirse a pdgf. |
| US20110301332A1 (en) * | 2008-07-01 | 2011-12-08 | Cephalon Australia (Vic) Pty Ltd. | Anti-pamp therapeutic antibodies |
| CN102272148A (zh) | 2008-11-03 | 2011-12-07 | 分子组合公司 | 抑制vegf-a受体相互作用的结合蛋白 |
| EP2470556B1 (en) | 2009-08-27 | 2018-05-30 | Covagen AG | Il-17 binding compounds and medical uses thereof |
| JP5667207B2 (ja) | 2009-12-14 | 2015-02-12 | シル プロテインズ ゲーエムベーハーＳｃｉｌ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ | リガンドへの結合能を有するヘテロ多量体修飾ユビキチンタンパク質の同定方法 |
| TR201906295T4 (tr) | 2010-06-08 | 2019-05-21 | Astrazeneca Ab | IL-4 R alfaya bağlanan gözyaşı lipokalini muteinleri. |
| BR112012032389A2 (pt) * | 2010-06-18 | 2016-10-25 | Brahms Gmbh | biomarcadores para a previsão de câncer incidente |
| JP6336911B2 (ja) * | 2011-11-16 | 2018-06-06 | シュピーンゴテック ゲゼルシャフト ミット ベシュレンクテル ハフツング | アドレノメジュリンアッセイおよび成熟アドレノメジュリンの測定方法 |
| PT2780371T (pt) | 2011-11-16 | 2019-01-30 | Adrenomed Ag | Anticorpo anti-adrenomedulina (adm) ou fragmento de anticorpo anti-adm ou uma estrutura não ig anti-adm para a regulação do equilíbrio de fluidos num doente com uma doença aguda ou crónica |
| JP6321544B2 (ja) | 2011-11-16 | 2018-05-09 | アドレノメト アクチェンゲゼルシャフト | 慢性若しくは急性疾患又は急性病態に罹患している患者の死亡リスクを低減するための抗アドレノメデュリン（ＡＤＭ）抗体、抗ＡＤＭ抗体フラグメント又は抗ＡＤＭ非Ｉｇ足場 |
| PT2780370T (pt) * | 2011-11-16 | 2019-10-30 | Adrenomed Ag | Anticorpo anti-adrenomedulina (adm) ou fragmento anticorpo anti-adm ou estrutura de anticorpo anti-adm não ig para utilização na terapia de uma doença aguda ou condição aguda de um paciente para estabilizar a circulação |
| SG10201801919QA (en) | 2011-11-16 | 2018-04-27 | Adrenomed Ag | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for prevention or reduction of organ dysfunction or organ failure in a patient having a chronic or acute disease or acute condition |
| WO2013072512A1 (en) * | 2011-11-16 | 2013-05-23 | Adrenomed Ag | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or an anti-adm non-ig scaffold for use in therapy |
-
2017
- 2017-12-18 CN CN201780077335.5A patent/CN110167962B/zh active Active
- 2017-12-18 WO PCT/EP2017/083311 patent/WO2018109228A1/en not_active Ceased
- 2017-12-18 MX MX2019007107A patent/MX2019007107A/es unknown
- 2017-12-18 AU AU2017375049A patent/AU2017375049B2/en active Active
- 2017-12-18 BR BR112019011713-0A patent/BR112019011713A2/pt unknown
- 2017-12-18 IL IL322765A patent/IL322765A/en unknown
- 2017-12-18 KR KR1020257017044A patent/KR20250084231A/ko active Pending
- 2017-12-18 KR KR1020197020162A patent/KR20190120174A/ko not_active Ceased
- 2017-12-18 CN CN202410627213.0A patent/CN118767128A/zh active Pending
- 2017-12-18 CA CA3046850A patent/CA3046850A1/en active Pending
- 2017-12-18 JP JP2019531740A patent/JP7727371B2/ja active Active
- 2017-12-18 RU RU2021135712A patent/RU2021135712A/ru unknown
- 2017-12-18 RU RU2019122135A patent/RU2762059C2/ru active
- 2017-12-18 US US16/469,738 patent/US20200299372A1/en not_active Abandoned
- 2017-12-18 EP EP17837953.3A patent/EP3555130A1/en active Pending
- 2017-12-18 KR KR1020247006366A patent/KR20240033285A/ko not_active Ceased
- 2017-12-18 MY MYPI2019003407A patent/MY208219A/en unknown
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2019
- 2019-06-12 IL IL267282A patent/IL267282A/en unknown
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2021
- 2021-06-04 US US17/339,221 patent/US20220041703A1/en active Pending
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2023
- 2023-01-25 JP JP2023009286A patent/JP2023052614A/ja active Pending
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2024
- 2024-08-23 JP JP2024143320A patent/JP2024170454A/ja active Pending
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2025
- 2025-04-29 AU AU2025202983A patent/AU2025202983A1/en active Pending