JP2020193229A5 - - Google Patents
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- Publication number
- JP2020193229A5 JP2020193229A5 JP2020147797A JP2020147797A JP2020193229A5 JP 2020193229 A5 JP2020193229 A5 JP 2020193229A5 JP 2020147797 A JP2020147797 A JP 2020147797A JP 2020147797 A JP2020147797 A JP 2020147797A JP 2020193229 A5 JP2020193229 A5 JP 2020193229A5
- Authority
- JP
- Japan
- Prior art keywords
- solid composition
- oral solid
- additive
- progestin
- production method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
- 239000000725 suspension Substances 0.000 claims description 6
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 claims description 3
- 229960004400 levonorgestrel Drugs 0.000 claims description 3
- 229940053934 norethindrone Drugs 0.000 claims description 3
- VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 claims description 3
- 239000008247 solid mixture Substances 0.000 claims 13
- 239000000654 additive Substances 0.000 claims 11
- 230000000996 additive effect Effects 0.000 claims 11
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims 9
- 239000000583 progesterone congener Substances 0.000 claims 9
- 238000004519 manufacturing process Methods 0.000 claims 7
- 229940079832 sodium starch glycolate Drugs 0.000 claims 6
- 229920003109 sodium starch glycolate Polymers 0.000 claims 6
- 239000008109 sodium starch glycolate Substances 0.000 claims 6
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 4
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 4
- VJHCJDRQFCCTHL-UHFFFAOYSA-N acetic acid 2,3,4,5,6-pentahydroxyhexanal Chemical compound CC(O)=O.OCC(O)C(O)C(O)C(O)C=O VJHCJDRQFCCTHL-UHFFFAOYSA-N 0.000 claims 4
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 4
- 229950008138 carmellose Drugs 0.000 claims 4
- 229960000913 crospovidone Drugs 0.000 claims 4
- 230000001186 cumulative effect Effects 0.000 claims 4
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 claims 4
- 239000002245 particle Substances 0.000 claims 4
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 claims 4
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 claims 4
- 229920002472 Starch Polymers 0.000 claims 3
- 235000019698 starch Nutrition 0.000 claims 3
- 238000000034 method Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 229920002261 Corn starch Polymers 0.000 claims 1
- 239000008120 corn starch Substances 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 238000005507 spraying Methods 0.000 claims 1
- 239000004615 ingredient Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019023844 | 2019-02-13 | ||
| JP2019023844 | 2019-02-13 | ||
| JP2020022783A JP6759478B2 (ja) | 2019-02-13 | 2020-02-13 | 経口固形組成物、その製造方法、及びその製造方法によって得られた経口用錠剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020022783A Division JP6759478B2 (ja) | 2019-02-13 | 2020-02-13 | 経口固形組成物、その製造方法、及びその製造方法によって得られた経口用錠剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020193229A JP2020193229A (ja) | 2020-12-03 |
| JP2020193229A5 true JP2020193229A5 (enrdf_load_stackoverflow) | 2021-04-30 |
| JP6955069B2 JP6955069B2 (ja) | 2021-10-27 |
Family
ID=72262312
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020022783A Active JP6759478B2 (ja) | 2019-02-13 | 2020-02-13 | 経口固形組成物、その製造方法、及びその製造方法によって得られた経口用錠剤 |
| JP2020147797A Active JP6955069B2 (ja) | 2019-02-13 | 2020-09-02 | 経口固形組成物、その製造方法、及びその製造方法によって得られた経口用錠剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020022783A Active JP6759478B2 (ja) | 2019-02-13 | 2020-02-13 | 経口固形組成物、その製造方法、及びその製造方法によって得られた経口用錠剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (2) | JP6759478B2 (enrdf_load_stackoverflow) |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69530308T2 (de) * | 1994-09-22 | 2003-10-16 | Akzo Nobel N.V., Arnheim/Arnhem | Verfahren zur herstellung von dosierungsformen durch feuchtgranulierung |
| CN100540008C (zh) * | 2002-11-14 | 2009-09-16 | 广州万方健医药有限公司 | 延迟固体口服避孕药或终止妊娠药溶解的剂型及其应用 |
| JP4756153B2 (ja) * | 2004-08-27 | 2011-08-24 | 富士製薬工業株式会社 | 低成分含量の錠剤の製造方法 |
| PT1848406E (pt) * | 2005-02-15 | 2008-08-21 | Jenapharm Gmbh | Forma de dosagem peroral sólida para a contracepção, compreendendo dienogest e etinilestradiol |
| US8475838B2 (en) * | 2005-06-03 | 2013-07-02 | Sandoz Ag | Rapidly-dissolving pharmaceutical composition for inhibiting ovulation |
| DE102005034498A1 (de) * | 2005-07-20 | 2007-01-25 | Grünenthal GmbH | Orale Kontrazeption mit Trimegeston |
| DE102007058842A1 (de) * | 2007-12-05 | 2009-06-10 | Grünenthal GmbH | Arzneimittel |
| US8157682B2 (en) * | 2009-07-17 | 2012-04-17 | The Gates Corporation | Tensioner |
| WO2012120365A1 (en) * | 2011-03-07 | 2012-09-13 | Aurobindo Pharma Limited | Stable pharmaceutical composition comprising ethinyl estradiol |
| CN103877058A (zh) * | 2014-03-26 | 2014-06-25 | 邵娜 | 一种左炔诺孕酮片及其制备工艺 |
| WO2017170858A1 (ja) * | 2016-03-31 | 2017-10-05 | 大日本住友製薬株式会社 | 溶出性に優れた経口製剤 |
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2020
- 2020-02-13 JP JP2020022783A patent/JP6759478B2/ja active Active
- 2020-09-02 JP JP2020147797A patent/JP6955069B2/ja active Active