JP2020073536A5 - - Google Patents

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Publication number
JP2020073536A5
JP2020073536A5 JP2019235539A JP2019235539A JP2020073536A5 JP 2020073536 A5 JP2020073536 A5 JP 2020073536A5 JP 2019235539 A JP2019235539 A JP 2019235539A JP 2019235539 A JP2019235539 A JP 2019235539A JP 2020073536 A5 JP2020073536 A5 JP 2020073536A5
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JP
Japan
Prior art keywords
nucleic acid
protein
seq
pharmaceutical composition
human
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JP2019235539A
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English (en)
Japanese (ja)
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JP6966532B2 (ja
JP2020073536A (ja
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Priority claimed from JP2017525514A external-priority patent/JP6654760B2/ja
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Publication of JP2020073536A publication Critical patent/JP2020073536A/ja
Publication of JP2020073536A5 publication Critical patent/JP2020073536A5/ja
Priority to JP2021172128A priority Critical patent/JP7198329B2/ja
Application granted granted Critical
Publication of JP6966532B2 publication Critical patent/JP6966532B2/ja
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JP2019235539A 2014-07-24 2019-12-26 網膜色素変性症のためのｒｐｇｒ遺伝子治療 Active JP6966532B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021172128A JP7198329B2 (ja) 2014-07-24 2021-10-21 網膜色素変性症のためのｒｐｇｒ遺伝子治療

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462028638P 2014-07-24 2014-07-24
US62/028,638 2014-07-24
JP2017525514A JP6654760B2 (ja) 2014-07-24 2015-07-17 網膜色素変性症のためのｒｐｇｒ遺伝子治療

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2017525514A Division JP6654760B2 (ja) 2014-07-24 2015-07-17 網膜色素変性症のためのｒｐｇｒ遺伝子治療

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021172128A Division JP7198329B2 (ja) 2014-07-24 2021-10-21 網膜色素変性症のためのｒｐｇｒ遺伝子治療

Publications (3)

Publication Number Publication Date
JP2020073536A JP2020073536A (ja) 2020-05-14
JP2020073536A5 true JP2020073536A5 (https=) 2020-12-03
JP6966532B2 JP6966532B2 (ja) 2021-11-17

Family

ID=55163577

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017525514A Active JP6654760B2 (ja) 2014-07-24 2015-07-17 網膜色素変性症のためのｒｐｇｒ遺伝子治療
JP2019235539A Active JP6966532B2 (ja) 2014-07-24 2019-12-26 網膜色素変性症のためのｒｐｇｒ遺伝子治療
JP2021172128A Active JP7198329B2 (ja) 2014-07-24 2021-10-21 網膜色素変性症のためのｒｐｇｒ遺伝子治療

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2017525514A Active JP6654760B2 (ja) 2014-07-24 2015-07-17 網膜色素変性症のためのｒｐｇｒ遺伝子治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021172128A Active JP7198329B2 (ja) 2014-07-24 2021-10-21 網膜色素変性症のためのｒｐｇｒ遺伝子治療

Country Status (18)

Country Link
US (2) US10314924B2 (https=)
EP (2) EP3821912B1 (https=)
JP (3) JP6654760B2 (https=)
CN (1) CN107206105A (https=)
CA (1) CA2991750C (https=)
CY (1) CY1123793T1 (https=)
DK (2) DK3821912T3 (https=)
ES (2) ES2987090T3 (https=)
FI (1) FI3821912T3 (https=)
HR (2) HRP20202023T1 (https=)
HU (2) HUE068183T2 (https=)
LT (2) LT3821912T (https=)
PL (2) PL3821912T3 (https=)
PT (2) PT3191139T (https=)
RS (2) RS65909B1 (https=)
SI (2) SI3191139T1 (https=)
SM (2) SMT202000715T1 (https=)
WO (1) WO2016014353A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE068183T2 (hu) * 2014-07-24 2024-12-28 Massachusetts Eye & Ear Infirmary RPGR génterápia a retinitis pigmentosa terápiájára
WO2016098078A2 (en) * 2014-12-19 2016-06-23 Novartis Ag Dimerization switches and uses thereof
EP3268481B1 (en) 2015-03-11 2020-05-27 The United States of America, as represented by The Secretary, Department of Health and Human Services Rpgr vectors for treating x-linked retinitis pigmentosa
GB201516066D0 (en) 2015-09-10 2015-10-28 Young & Co Llp D Treatment of retinitis pigmentosa
GB201704192D0 (en) 2017-03-16 2017-05-03 Nightstarx Ltd Treatment of Retinitis Pigmentosa
CN111867635A (zh) * 2017-10-20 2020-10-30 法国国家卫生及研究医学协会 包括视网膜下递送治疗有效量的重组aav9衍生载体的在对象的视锥细胞光感受器中表达目的多核苷酸的方法
KR102704296B1 (ko) * 2017-11-15 2024-09-05 더 리젠츠 오브 더 유니버시티 오브 미시간 Rdh12 암호화 영역을 포함하는 바이러스 벡터 및 망막 이영양증을 치료하는 방법
EP4117644A4 (en) 2020-03-11 2024-08-14 Massachusetts Eye and Ear Infirmary GENE THERAPY FOR NMNAT1-ASSOCIATED RETINAL DEGENERATION
CN120350069A (zh) * 2024-01-12 2025-07-22 北京中因科技有限公司 视网膜色素变性动物模型及其构建方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980286A (en) 1985-07-05 1990-12-25 Whitehead Institute For Biomedical Research In vivo introduction and expression of foreign genetic material in epithelial cells
IL79289A (en) 1985-07-05 1992-01-15 Whitehead Biomedical Inst Introduction and expression of foreign genetic material into keratinocytes using a recombinant retrovirus
ATE117375T1 (de) 1987-09-11 1995-02-15 Whitehead Biomedical Inst Transduktionsveränderte fibroblasten und ihre anwendung.
JP2914692B2 (ja) 1987-12-11 1999-07-05 ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ 内皮細胞の遺伝子修飾
WO1989007136A2 (en) 1988-02-05 1989-08-10 Whitehead Institute For Biomedical Research Modified hepatocytes and uses therefor
ES2096750T3 (es) 1990-10-31 1997-03-16 Somatix Therapy Corp Vectores retroviricos utiles para la terapia genica.
US5767079A (en) * 1992-07-08 1998-06-16 Celtrix Pharmaceuticals, Inc. Method of treating ophthalmic disorders using TGF -β
AU2044901A (en) * 1999-11-24 2001-06-04 Cornell Research Foundation Inc. Inherited retinal diseases at the canine rp3 locus: linkage, marker- and mutation-based tests
GB0008801D0 (en) * 2000-04-10 2000-05-31 Medical Res Council Sequences
CN102925445A (zh) * 2011-08-08 2013-02-13 刘军 一种获得rpgr 基因新的转录剪切形式的方法
EP2872183B1 (en) * 2012-07-11 2018-09-26 The Trustees Of The University Of Pennsylvania Aav-mediated gene therapy for rpgr x-linked retinal degeneration
GB201412011D0 (en) * 2014-07-04 2014-08-20 Ucl Business Plc Treatments
HUE068183T2 (hu) * 2014-07-24 2024-12-28 Massachusetts Eye & Ear Infirmary RPGR génterápia a retinitis pigmentosa terápiájára

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