JP2019534046A5 - - Google Patents
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- Publication number
- JP2019534046A5 JP2019534046A5 JP2019545868A JP2019545868A JP2019534046A5 JP 2019534046 A5 JP2019534046 A5 JP 2019534046A5 JP 2019545868 A JP2019545868 A JP 2019545868A JP 2019545868 A JP2019545868 A JP 2019545868A JP 2019534046 A5 JP2019534046 A5 JP 2019534046A5
- Authority
- JP
- Japan
- Prior art keywords
- zinc
- kda
- composition
- dosage form
- solid dosage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 41
- 238000000034 method Methods 0.000 claims 18
- 150000003751 zinc Chemical class 0.000 claims 17
- 229920002643 polyglutamic acid Polymers 0.000 claims 15
- 239000007909 solid dosage form Substances 0.000 claims 15
- 239000011701 zinc Substances 0.000 claims 14
- 229910052725 zinc Inorganic materials 0.000 claims 14
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 13
- 230000002496 gastric effect Effects 0.000 claims 13
- 239000011230 binding agent Substances 0.000 claims 12
- 239000006194 liquid suspension Substances 0.000 claims 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 6
- 239000008187 granular material Substances 0.000 claims 6
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 claims 4
- 239000004067 bulking agent Substances 0.000 claims 4
- 239000001913 cellulose Substances 0.000 claims 4
- 229920002678 cellulose Polymers 0.000 claims 4
- 239000007884 disintegrant Substances 0.000 claims 4
- 239000000314 lubricant Substances 0.000 claims 4
- ARCGXLSVLAOJQL-UHFFFAOYSA-N trimellitic acid Chemical compound OC(=O)C1=CC=C(C(O)=O)C(C(O)=O)=C1 ARCGXLSVLAOJQL-UHFFFAOYSA-N 0.000 claims 4
- 239000011248 coating agent Substances 0.000 claims 3
- 238000000576 coating method Methods 0.000 claims 3
- 238000001035 drying Methods 0.000 claims 3
- 238000005469 granulation Methods 0.000 claims 3
- 230000003179 granulation Effects 0.000 claims 3
- 239000002904 solvent Substances 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 238000005550 wet granulation Methods 0.000 claims 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 2
- 229920001800 Shellac Polymers 0.000 claims 2
- 229920002494 Zein Polymers 0.000 claims 2
- IYKJEILNJZQJPU-UHFFFAOYSA-N acetic acid;butanedioic acid Chemical compound CC(O)=O.OC(=O)CCC(O)=O IYKJEILNJZQJPU-UHFFFAOYSA-N 0.000 claims 2
- GAMPNQJDUFQVQO-UHFFFAOYSA-N acetic acid;phthalic acid Chemical compound CC(O)=O.OC(=O)C1=CC=CC=C1C(O)=O GAMPNQJDUFQVQO-UHFFFAOYSA-N 0.000 claims 2
- 125000005396 acrylic acid ester group Chemical group 0.000 claims 2
- 229920002301 cellulose acetate Polymers 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 230000037406 food intake Effects 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 239000000178 monomer Substances 0.000 claims 2
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 claims 2
- 229940100467 polyvinyl acetate phthalate Drugs 0.000 claims 2
- 239000000661 sodium alginate Substances 0.000 claims 2
- 235000010413 sodium alginate Nutrition 0.000 claims 2
- 229940005550 sodium alginate Drugs 0.000 claims 2
- 239000005019 zein Substances 0.000 claims 2
- 229940093612 zein Drugs 0.000 claims 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical group [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 1
- 108010020346 Polyglutamic Acid Proteins 0.000 claims 1
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims 1
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000013522 chelant Substances 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 229930195712 glutamate Natural products 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000002562 thickening agent Substances 0.000 claims 1
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 claims 1
- 239000004246 zinc acetate Substances 0.000 claims 1
- 229960000314 zinc acetate Drugs 0.000 claims 1
- 239000011592 zinc chloride Substances 0.000 claims 1
- 235000005074 zinc chloride Nutrition 0.000 claims 1
- 229960001939 zinc chloride Drugs 0.000 claims 1
- 239000011746 zinc citrate Substances 0.000 claims 1
- 235000006076 zinc citrate Nutrition 0.000 claims 1
- 229940068475 zinc citrate Drugs 0.000 claims 1
- 239000011670 zinc gluconate Substances 0.000 claims 1
- 235000011478 zinc gluconate Nutrition 0.000 claims 1
- 229960000306 zinc gluconate Drugs 0.000 claims 1
- 229940032991 zinc picolinate Drugs 0.000 claims 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims 1
- 229960001763 zinc sulfate Drugs 0.000 claims 1
- 229910000368 zinc sulfate Inorganic materials 0.000 claims 1
- NHVUUBRKFZWXRN-UHFFFAOYSA-L zinc;pyridine-2-carboxylate Chemical compound C=1C=CC=NC=1C(=O)O[Zn]OC(=O)C1=CC=CC=N1 NHVUUBRKFZWXRN-UHFFFAOYSA-L 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022144662A JP2023016043A (ja) | 2016-11-01 | 2022-09-12 | ガンマ－ポリグルタミン酸および亜鉛組成物 |
| JP2025117126A JP2025148479A (ja) | 2016-11-01 | 2025-07-11 | ガンマ－ポリグルタミン酸および亜鉛組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201609137P | 2016-11-01 | ||
| SG10201609137PA SG10201609137PA (en) | 2016-11-01 | 2016-11-01 | Gamma-polyglutamic acid and zinc compositions |
| PCT/SG2017/050544 WO2018084805A1 (en) | 2016-11-01 | 2017-10-31 | Gamma-polyglutamic acid and zinc compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022144662A Division JP2023016043A (ja) | 2016-11-01 | 2022-09-12 | ガンマ－ポリグルタミン酸および亜鉛組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019534046A JP2019534046A (ja) | 2019-11-28 |
| JP2019534046A5 true JP2019534046A5 (enExample) | 2020-12-10 |
Family
ID=60582642
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019545868A Pending JP2019534046A (ja) | 2016-11-01 | 2017-10-31 | ガンマ−ポリグルタミン酸および亜鉛組成物 |
| JP2022144662A Pending JP2023016043A (ja) | 2016-11-01 | 2022-09-12 | ガンマ－ポリグルタミン酸および亜鉛組成物 |
| JP2025117126A Pending JP2025148479A (ja) | 2016-11-01 | 2025-07-11 | ガンマ－ポリグルタミン酸および亜鉛組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022144662A Pending JP2023016043A (ja) | 2016-11-01 | 2022-09-12 | ガンマ－ポリグルタミン酸および亜鉛組成物 |
| JP2025117126A Pending JP2025148479A (ja) | 2016-11-01 | 2025-07-11 | ガンマ－ポリグルタミン酸および亜鉛組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20190247428A1 (enExample) |
| EP (1) | EP3534915B1 (enExample) |
| JP (3) | JP2019534046A (enExample) |
| KR (1) | KR20190122203A (enExample) |
| CN (1) | CN108014130A (enExample) |
| AU (2) | AU2017354786B2 (enExample) |
| CA (1) | CA3042234A1 (enExample) |
| DK (1) | DK3534915T3 (enExample) |
| ES (1) | ES2969208T3 (enExample) |
| MX (2) | MX2019005103A (enExample) |
| SG (2) | SG10201609137PA (enExample) |
| WO (1) | WO2018084805A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102094182B1 (ko) * | 2018-06-28 | 2020-03-30 | 주식회사 알랙스탠드 | 아연 함유 수용성 폴리글루타믹산 복합체 조성물 |
| WO2023168365A1 (en) | 2022-03-02 | 2023-09-07 | Jds Therapeutics, Llc | Polyglutamic acid compositions and methods of using |
| CN117224690B (zh) * | 2023-11-10 | 2024-01-30 | 江苏海王健康生物科技有限公司 | 一种作为助剂的γ-聚谷氨酸混合物、组合物、制备方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2712583B2 (ja) * | 1989-06-28 | 1998-02-16 | 味の素株式会社 | 易吸収性ミネラル含有飲食物 |
| JP3232718B2 (ja) * | 1992-03-24 | 2001-11-26 | 味の素株式会社 | 易吸収性ミネラル含有組成物及びそれを含有する飲食品 |
| JP3551149B2 (ja) * | 1992-03-24 | 2004-08-04 | 味の素株式会社 | 易吸収性ミネラル含有組成物及びそれを含有する飲食品 |
| US5447732A (en) * | 1992-11-25 | 1995-09-05 | Ajinomoto Co., Inc. | High-absorption mineral-containing composition and foods |
| IT1275923B1 (it) * | 1995-03-16 | 1997-10-24 | Valpharma Sa | Formulazioni gastroresistenti contenenti zinco |
| JPH11313618A (ja) * | 1998-05-06 | 1999-11-16 | Yoshio Inoue | 胃にやさしい家畜用ミネラル（亜鉛）製剤及びその製造法 |
| WO2004080210A1 (en) * | 2003-03-14 | 2004-09-23 | Boehringer Ingelheim Danmark A/S | Compositions of dietary metals for support of the physiological intestinal development and prevention of diarrhoea |
| JP4457641B2 (ja) * | 2003-11-10 | 2010-04-28 | 味の素株式会社 | ゼラチンカプセル |
| JP5162812B2 (ja) * | 2004-07-08 | 2013-03-13 | 大正製薬株式会社 | 亜鉛含有経口投与用組成物 |
| JPWO2007043606A1 (ja) * | 2005-10-12 | 2009-04-16 | 株式会社ジェノラックＢｌ | アニオン性ポリアミノ酸／金属複合体からなる抗糖尿病薬剤 |
| JP2012523413A (ja) * | 2009-04-10 | 2012-10-04 | サイプレス ファーマシューティカルズ， インコーポレイテッド | ホスフェート結合性マグネシウム塩およびその使用 |
| JO3635B1 (ar) * | 2009-05-18 | 2020-08-27 | Millennium Pharm Inc | مركبات صيدلانية صلبة وطرق لانتاجها |
| CN101692851B (zh) * | 2009-10-20 | 2014-01-08 | 华中农业大学 | γ-聚谷氨酸或其盐类作为添加剂在乳制品中的应用 |
| CN101716180B (zh) * | 2009-11-06 | 2013-04-24 | 广西强寿药业集团有限公司 | 一种组合补充锌、钙药物及其制备方法 |
| CA2800235C (en) * | 2010-03-10 | 2018-10-16 | Lupin Limited | Rifaximin ready-to-use suspension |
| KR101892788B1 (ko) * | 2011-09-13 | 2018-08-28 | 파마싸이클릭스 엘엘씨 | 벤다무스틴과 조합된 히스톤 디아세틸라제 억제제의 제제 및 그의 용도 |
| ES2646927T3 (es) * | 2012-11-21 | 2017-12-18 | KBS Research, LLC | Suplementos herbales y métodos de uso de los mismos |
| TWI660748B (zh) * | 2013-03-01 | 2019-06-01 | 日商大塚製藥股份有限公司 | 用於口服投藥之包含非晶型托伐普坦（Ｔｏｌｖａｐｔａｎ）的懸浮液 |
| CN103690521B (zh) * | 2013-11-29 | 2016-07-06 | 湖北福人金身药业有限公司 | 一种葡萄糖酸钙锌口服溶液 |
| JP2016069303A (ja) * | 2014-09-29 | 2016-05-09 | タカラバイオ株式会社 | フコイダンを有効成分とする脱毛抑制用組成物 |
| ES2630106T3 (es) * | 2014-10-07 | 2017-08-18 | Cyprumed Gmbh | Formulaciones farmacéuticas para la administración oral de fármacos peptídicos o proteicos |
| KR102467968B1 (ko) * | 2014-10-08 | 2022-11-16 | 신세틱 바이오로직스, 인코퍼레이티드 | 베타-락타마제 제형 및 이의 용도 |
| WO2016088816A1 (ja) * | 2014-12-03 | 2016-06-09 | ノーベルファーマ株式会社 | 酢酸亜鉛水和物錠及びその製造方法 |
-
2016
- 2016-11-01 SG SG10201609137PA patent/SG10201609137PA/en unknown
-
2017
- 2017-10-31 SG SG11201903732TA patent/SG11201903732TA/en unknown
- 2017-10-31 EP EP17809399.3A patent/EP3534915B1/en active Active
- 2017-10-31 JP JP2019545868A patent/JP2019534046A/ja active Pending
- 2017-10-31 ES ES17809399T patent/ES2969208T3/es active Active
- 2017-10-31 US US16/346,283 patent/US20190247428A1/en not_active Abandoned
- 2017-10-31 MX MX2019005103A patent/MX2019005103A/es unknown
- 2017-10-31 AU AU2017354786A patent/AU2017354786B2/en active Active
- 2017-10-31 CA CA3042234A patent/CA3042234A1/en active Pending
- 2017-10-31 DK DK17809399.3T patent/DK3534915T3/da active
- 2017-10-31 WO PCT/SG2017/050544 patent/WO2018084805A1/en not_active Ceased
- 2017-10-31 KR KR1020197015742A patent/KR20190122203A/ko not_active Ceased
- 2017-11-01 CN CN201711096131.4A patent/CN108014130A/zh active Pending
-
2019
- 2019-04-30 MX MX2022013541A patent/MX2022013541A/es unknown
-
2022
- 2022-09-12 JP JP2022144662A patent/JP2023016043A/ja active Pending
-
2023
- 2023-05-23 AU AU2023203216A patent/AU2023203216B2/en active Active
-
2024
- 2024-08-08 US US18/797,689 patent/US20250041333A1/en active Pending
-
2025
- 2025-07-11 JP JP2025117126A patent/JP2025148479A/ja active Pending
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