|
AU561343B2
(en)
|
1981-10-19 |
1987-05-07 |
Genentech Inc. |
Human immune interferon by recombinant dna
|
|
DE3377363D1
(en)
|
1982-03-31 |
1988-08-18 |
Ajinomoto Kk |
Gene coding for interleukin-2 polypeptide, recombinant dna carrying said gene, cell lines possessing the recombinant dna,and method for producing interleukin-2 using said cells
|
|
US4966843A
(en)
|
1982-11-01 |
1990-10-30 |
Cetus Corporation |
Expression of interferon genes in Chinese hamster ovary cells
|
|
US4892743A
(en)
|
1983-12-21 |
1990-01-09 |
Schering Corporation |
Novel hybrid interferon species
|
|
EP0165942A1
(en)
|
1983-12-23 |
1986-01-02 |
Monash University |
PRODUCTION OF HUMAN INTERFERON-$g(a)
|
|
AU594014B2
(en)
|
1984-03-21 |
1990-03-01 |
Research Corporation Technologies, Inc. |
Recombinant DNA molecules
|
|
US4810643A
(en)
|
1985-08-23 |
1989-03-07 |
Kirin- Amgen Inc. |
Production of pluripotent granulocyte colony-stimulating factor
|
|
JPS63500636A
(ja)
|
1985-08-23 |
1988-03-10 |
麒麟麦酒株式会社 |
多分化能性顆粒球コロニー刺激因子をコードするｄｎａ
|
|
US5017691A
(en)
|
1986-07-03 |
1991-05-21 |
Schering Corporation |
Mammalian interleukin-4
|
|
US5116742A
(en)
|
1986-12-03 |
1992-05-26 |
University Patents, Inc. |
RNA ribozyme restriction endoribonucleases and methods
|
|
PT92479A
(pt)
|
1988-12-01 |
1990-06-29 |
Univ North Carolina |
Processo de preparacao de genes recombinantes e suas proteinas de codificacao
|
|
US5225337A
(en)
|
1989-09-25 |
1993-07-06 |
Innovir Laboratories, Inc. |
Ribozyme compositions and methods for use
|
|
US5246921A
(en)
|
1990-06-26 |
1993-09-21 |
The Wistar Institute Of Anatomy And Biology |
Method for treating leukemias
|
|
WO1995003777A1
(en)
|
1993-08-02 |
1995-02-09 |
The Scripps Research Institute |
Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus
|
|
US5780036A
(en)
|
1991-08-26 |
1998-07-14 |
The Scripps Research Institute |
Peptides for inducing cytotoxic T lymphocyte responses to hepattis B virus
|
|
SE9401709D0
(sv)
|
1994-05-18 |
1994-05-18 |
Mathilda Sjoeberg |
Improved alphavirus vectors for expression of heterologous DNA
|
|
US5792462A
(en)
|
1995-05-23 |
1998-08-11 |
University Of North Carolina At Chapel Hill |
Alphavirus RNA replicon systems
|
|
US6041252A
(en)
|
1995-06-07 |
2000-03-21 |
Ichor Medical Systems Inc. |
Drug delivery system and method
|
|
DE19712889A1
(de)
|
1997-03-27 |
1998-10-01 |
Bosch Gmbh Robert |
Verfahren und Vorrichtung zur Ermittlung einer den Systemdruck in einem Bremskreis beschreibenden Größe
|
|
CA2285056C
(en)
|
1997-04-03 |
2004-12-14 |
Iacob Mathiesen |
Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle
|
|
US6261281B1
(en)
|
1997-04-03 |
2001-07-17 |
Electrofect As |
Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
|
|
US5873849A
(en)
|
1997-04-24 |
1999-02-23 |
Ichor Medical Systems, Inc. |
Electrodes and electrode arrays for generating electroporation inducing electrical fields
|
|
GB0023203D0
(en)
|
2000-09-21 |
2000-11-01 |
Isis Innovation |
Vaccination method
|
|
US6117660A
(en)
|
1997-06-10 |
2000-09-12 |
Cytopulse Sciences, Inc. |
Method and apparatus for treating materials with electrical fields having varying orientations
|
|
AU8444798A
(en)
|
1997-06-30 |
1999-01-25 |
Centre National De La Recherche Scientifique |
Improved method for transferring nucleic acid into the striped muscle and combination therefor
|
|
US5958060A
(en)
|
1998-01-02 |
1999-09-28 |
General Electric Company |
Method and apparatus for clock control and synchronization
|
|
US6697669B2
(en)
|
1998-07-13 |
2004-02-24 |
Genetronics, Inc. |
Skin and muscle-targeted gene therapy by pulsed electrical field
|
|
US6319901B1
(en)
|
1998-10-15 |
2001-11-20 |
Ichor Medical Systems, Inc. |
Methods for prolonging cell membrane permeability
|
|
US20040213805A1
(en)
|
1999-10-12 |
2004-10-28 |
Verheije Monique Helene |
Deletions in arterivirus replicons
|
|
US6982087B2
(en)
|
2000-09-07 |
2006-01-03 |
The University Of North Carolina At Chapel Hill |
Vectors derived from South African Arbovirus No. 86
|
|
US6538922B1
(en)
|
2000-09-27 |
2003-03-25 |
Sandisk Corporation |
Writable tracking cells
|
|
UA76731C2
(uk)
|
2000-11-23 |
2006-09-15 |
Баваріан Нордік А/С |
Штам mva-bn модифікованого вірусу коров'ячої віспи ankara, фармацевтична композиція, вакцина, застосування mva-bn для приготування лікарського препарату та для приготування вакцини, спосіб введення гомологічної і/або гетерологічної послідовності нуклеїнової кислоти в клітини-мішені in vitro, спосіб одержання пептиду або білка, спосіб одержання mva-bn, клітина, набір для основної/бустерної імунізації
|
|
WO2002061113A2
(en)
|
2001-02-01 |
2002-08-08 |
The Johns Hopkins University |
Nucleic acid derived vaccine that encodes an antigen linked to a polypeptide that promotes antigen presentation
|
|
EP1278382B1
(en)
|
2001-07-19 |
2007-02-14 |
Telefonaktiebolaget LM Ericsson (publ) |
Method and apparatus for solving number portability in origin
|
|
US8209006B2
(en)
|
2002-03-07 |
2012-06-26 |
Vgx Pharmaceuticals, Inc. |
Constant current electroporation device and methods of use
|
|
US7245963B2
(en)
|
2002-03-07 |
2007-07-17 |
Advisys, Inc. |
Electrode assembly for constant-current electroporation and use
|
|
US6912417B1
(en)
|
2002-04-05 |
2005-06-28 |
Ichor Medical Systmes, Inc. |
Method and apparatus for delivery of therapeutic agents
|
|
US7328064B2
(en)
|
2002-07-04 |
2008-02-05 |
Inovio As |
Electroporation device and injection apparatus
|
|
WO2004055161A2
(en)
|
2002-12-12 |
2004-07-01 |
The Board Of Regents Of The University Of Texas System |
Large scale production of packaged alphavirus replicons
|
|
US8080255B2
(en)
|
2003-07-11 |
2011-12-20 |
Novavax Inc. |
Functional influenza virus like particles (VLPs)
|
|
DE602004021260D1
(de)
|
2003-07-11 |
2009-07-09 |
Alphavax Inc |
Cytomegalovirusimpfstoffe, die auf dem alphavirus basieren
|
|
US20050070700A1
(en)
|
2003-09-30 |
2005-03-31 |
Matthias Giese |
Equine arteritis virus vaccine
|
|
HUE025052T2
(en)
|
2004-03-08 |
2016-01-28 |
Ichor Medical Systems Inc |
A sharpened device for electrically mediated delivery of medical substances
|
|
US8859198B2
(en)
|
2006-06-06 |
2014-10-14 |
Abl Sa |
Detection and use of antiviral resistance mutations
|
|
US20120121650A1
(en)
*
|
2006-08-18 |
2012-05-17 |
Johnston Robert E |
Chimeric Virus Vaccines
|
|
CA2666501C
(en)
|
2006-10-17 |
2017-03-21 |
Vgx Pharmaceuticals, Inc. |
Electroporation devices and methods of using same for electroporation of cells in mammals
|
|
WO2008073303A2
(en)
|
2006-12-07 |
2008-06-19 |
Switchgear Genomics |
Transcriptional regulatory elements of biological pathways, tools, and methods
|
|
KR100836745B1
(ko)
|
2007-01-31 |
2008-06-10 |
(주)두비엘 |
Ｈｂｖ 백신 및 그의 제조 방법
|
|
US8460913B2
(en)
*
|
2007-06-21 |
2013-06-11 |
Alpha Vax, Inc. |
Promoterless cassettes for expression of alpha virus structural proteins
|
|
WO2009056535A2
(en)
|
2007-10-29 |
2009-05-07 |
Genimmune N.V. |
Methods and kits for inducing a ctl response using a prime boost regimen
|
|
RU2555346C2
(ru)
|
2009-08-07 |
2015-07-10 |
Трансген Са |
Композиция для лечения инфекции вирусом гепатита в
|
|
ES2647662T3
(es)
|
2009-12-31 |
2017-12-26 |
Medigen, Inc. |
Vacunas de ADN infeccioso frente al virus chikungunya
|
|
ES2646669T3
(es)
|
2010-07-06 |
2017-12-14 |
Glaxosmithkline Biologicals Sa |
Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN
|
|
EP2655621B1
(en)
|
2010-12-20 |
2018-05-23 |
The General Hospital Corporation |
Polycomb-associated non-coding rnas
|
|
EA032364B1
(ru)
|
2011-02-11 |
2019-05-31 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу
|
|
CA2837214C
(en)
|
2011-06-28 |
2021-06-01 |
Inovio Pharmaceuticals, Inc. |
A minimally invasive dermal electroporation device
|
|
TWI623618B
(zh)
|
2011-07-12 |
2018-05-11 |
傳斯堅公司 |
Ｈｂｖ聚合酶突變體
|
|
US8961995B2
(en)
*
|
2012-09-20 |
2015-02-24 |
Uab Research Foundation |
Methods and compositions for alphavirus replicons
|
|
JP6240090B2
(ja)
|
2012-12-13 |
2017-11-29 |
パナソニックヘルスケアホールディングス株式会社 |
薬剤注入装置
|
|
WO2014170493A2
(en)
*
|
2013-04-19 |
2014-10-23 |
Novartis Ag |
Alphavirus vector
|
|
AU2014310935B2
(en)
|
2013-08-21 |
2019-11-21 |
CureVac SE |
Combination vaccine
|
|
WO2016020538A1
(en)
|
2014-08-08 |
2016-02-11 |
Transgene Sa |
Hbv vaccine and antibody combination therapy to treat hbv infections
|
|
KR20230145241A
(ko)
|
2014-10-01 |
2023-10-17 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
항원 및 어쥬번트로서 인터류킨-21을 갖는 백신
|
|
JP6961490B2
(ja)
|
2015-04-08 |
2021-11-05 |
ノバルティス アーゲー |
Ｃｄ２０療法、ｃｄ２２療法、およびｃｄ１９キメラ抗原受容体（ｃａｒ）発現細胞との併用療法
|
|
WO2016184822A1
(en)
|
2015-05-15 |
2016-11-24 |
Curevac Ag |
Prime-boost regimens involving administration of at least one mrna construct
|
|
EP4137150A1
(en)
|
2015-08-03 |
2023-02-22 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use
|
|
WO2017059902A1
(en)
*
|
2015-10-07 |
2017-04-13 |
Biontech Rna Pharmaceuticals Gmbh |
3' utr sequences for stabilization of rna
|
|
AU2017241925B2
(en)
|
2016-03-28 |
2022-01-13 |
Ichor Medical Systems, Inc. |
Method and apparatus for delivery of therapeutic agents
|
|
EP3439696A4
(en)
|
2016-04-06 |
2019-12-25 |
University of Washington |
THERAPEUTIC VACCINE AGAINST THE HEPATITIS B VIRUS (HBV) USING THE HBV CORE ANTIGEN
|
|
JP7250520B2
(ja)
|
2016-04-13 |
2023-04-03 |
ヤンセン ファーマシューティカルズ，インコーポレーテッド |
組換えアルテリウイルスレプリコン系およびその使用
|
|
KR102718353B1
(ko)
|
2016-10-17 |
2024-10-15 |
얀센 파마슈티칼즈, 인코포레이티드 |
재조합 바이러스 레플리콘 시스템 및 그의 용도
|
|
CA3045650A1
(en)
|
2016-12-05 |
2018-06-14 |
Janssen Pharmaceuticals, Inc. |
Compositions and methods for enhancing gene expression
|
|
EP3607968A4
(en)
|
2017-06-05 |
2021-03-31 |
Beacle Inc. |
VIRAL-TYPE PARTICLES INTENDED FOR USE TO INDUCE AN IMMUNE RESPONSE AGAINST HBV
|
|
CN111542340B
(zh)
|
2017-11-16 |
2023-12-19 |
华盛顿大学 |
治疗性乙型肝炎病毒(hbv)疫苗
|
|
CN111836641A
(zh)
|
2017-12-19 |
2020-10-27 |
杨森科学爱尔兰无限公司 |
乙型肝炎病毒(hbv)疫苗及其用途
|
|
JP7494117B2
(ja)
*
|
2018-01-19 |
2024-06-03 |
ヤンセン ファーマシューティカルズ，インコーポレーテッド |
組換えレプリコン系を使用する免疫応答の誘導および増強
|