|
GB2116183B
(en)
|
1982-03-03 |
1985-06-05 |
Genentech Inc |
Human antithrombin iii dna sequences therefore expression vehicles and cloning vectors containing such sequences and cell cultures transformed thereby a process for expressing human antithrombin iii and pharmaceutical compositions comprising it
|
|
CA2143519A1
(en)
*
|
1994-03-11 |
1995-09-12 |
F. Hoffmann-La Roche Ag |
Beta-lactams
|
|
DK0920505T3
(da)
|
1996-08-16 |
2008-09-08 |
Schering Corp |
Pattedyrcelleoverfladeantigener og tilhörende reagenser
|
|
US6111090A
(en)
|
1996-08-16 |
2000-08-29 |
Schering Corporation |
Mammalian cell surface antigens; related reagents
|
|
CA2308114A1
(en)
|
1997-10-21 |
1999-04-29 |
Human Genome Sciences, Inc. |
Human tumor necrosis factor receptor-like proteins tr11, tr11sv1, and tr11sv2
|
|
JP2002502607A
(ja)
|
1998-02-09 |
2002-01-29 |
ジェネンテク・インコーポレイテッド |
新規な腫瘍壊死因子レセプター相同体及びそれをコードする核酸
|
|
ATE376837T1
(de)
|
1999-07-12 |
2007-11-15 |
Genentech Inc |
Stimulierung oder hemmung von angiogenese und herzvaskularisierung mit tumor nekrose faktor ligand/rezeptor homologen
|
|
FR2812635B1
(fr)
|
2000-08-01 |
2002-10-11 |
Aventis Pharma Sa |
Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
|
|
FR2825705B1
(fr)
|
2001-06-08 |
2005-05-20 |
Aventis Pharma Sa |
Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
|
|
FR2835186B1
(fr)
|
2002-01-28 |
2006-10-20 |
Aventis Pharma Sa |
Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
|
|
WO2004078163A2
(en)
|
2003-02-28 |
2004-09-16 |
Transform Pharmaceuticals, Inc. |
Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
|
|
US7439253B2
(en)
|
2002-12-06 |
2008-10-21 |
Novexel |
Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
|
|
FR2848210B1
(fr)
|
2002-12-06 |
2007-10-19 |
Aventis Pharma Sa |
Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases
|
|
ES2367430T3
(es)
|
2002-12-23 |
2011-11-03 |
Wyeth Llc |
Anticuerpos contra pd-1 y sus usos.
|
|
AU2004244626A1
(en)
|
2003-05-23 |
2004-12-09 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
GITR ligand and GITR ligand-related molecules and antibodies and uses thereof
|
|
EP1660126A1
(en)
|
2003-07-11 |
2006-05-31 |
Schering Corporation |
Agonists or antagonists of the clucocorticoid-induced tumour necrosis factor receptor (gitr) or its ligand for the treatment of immune disorders, infections and cancer
|
|
EP1692318A4
(en)
|
2003-12-02 |
2008-04-02 |
Genzyme Corp |
COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF LUNG CANCER
|
|
GB0409799D0
(en)
|
2004-04-30 |
2004-06-09 |
Isis Innovation |
Method of generating improved immune response
|
|
EP1765402A2
(en)
|
2004-06-04 |
2007-03-28 |
Duke University |
Methods and compositions for enhancement of immunity by in vivo depletion of immunosuppressive cell activity
|
|
JP5238936B2
(ja)
|
2005-03-25 |
2013-07-17 |
ジーアイティーアール,インク. |
Gitr結合分子およびその使用
|
|
EP3530736A3
(en)
|
2005-05-09 |
2019-11-06 |
ONO Pharmaceutical Co., Ltd. |
Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
|
|
KR101704734B1
(ko)
|
2005-07-01 |
2017-02-09 |
이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. |
예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
|
|
WO2007133822A1
(en)
|
2006-01-19 |
2007-11-22 |
Genzyme Corporation |
Gitr antibodies for the treatment of cancer
|
|
WO2008039420A2
(en)
|
2006-09-27 |
2008-04-03 |
Merck & Co., Inc. |
Novel inhibitors of beta-lactamase
|
|
PT2170959E
(pt)
|
2007-06-18 |
2014-01-07 |
Merck Sharp & Dohme |
Anticorpos para o receptor humano de morte programada pd-1
|
|
PT2175884T
(pt)
|
2007-07-12 |
2016-09-21 |
Gitr Inc |
Terapias de combinação empregando moléculas de ligação a gitr
|
|
JP5038509B2
(ja)
*
|
2008-01-18 |
2012-10-03 |
メルク・シャープ・エンド・ドーム・コーポレイション |
β−ラクタマーゼ阻害剤
|
|
PT2242773T
(pt)
|
2008-02-11 |
2017-09-15 |
Cure Tech Ltd |
Anticorpos monoclonais para o tratamento de tumores
|
|
US8168757B2
(en)
|
2008-03-12 |
2012-05-01 |
Merck Sharp & Dohme Corp. |
PD-1 binding proteins
|
|
JP2011526794A
(ja)
|
2008-07-02 |
2011-10-20 |
エマージェント プロダクト デベロップメント シアトル, エルエルシー |
TGF−βアンタゴニスト多重標的結合性分子
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
EA201500417A1
(ru)
|
2008-08-25 |
2015-11-30 |
Эмплиммьюн, Инк. |
Композиции антагонистов pd-1 и способы применения
|
|
WO2010098788A2
(en)
|
2008-08-25 |
2010-09-02 |
Amplimmune, Inc. |
Pd-i antagonists and methods for treating infectious disease
|
|
JPWO2010030002A1
(ja)
|
2008-09-12 |
2012-02-02 |
国立大学法人三重大学 |
外来性gitrリガンド発現細胞
|
|
FR2936951B1
(fr)
|
2008-10-10 |
2010-12-03 |
Novexel |
Nouvelles combinaisons de composes heterocycliques azotes antibacteriens avec d'autres composes antibacteriens et leur utilisation comme medicaments
|
|
MX356367B
(es)
|
2008-12-09 |
2018-05-25 |
Genentech Inc |
Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
|
|
WO2010089411A2
(en)
|
2009-02-09 |
2010-08-12 |
Universite De La Mediterranee |
Pd-1 antibodies and pd-l1 antibodies and uses thereof
|
|
WO2010126820A2
(en)
|
2009-04-30 |
2010-11-04 |
Merck Sharp & Dohme Corp. |
Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids
|
|
IN2015DN02826A
(enExample)
|
2009-09-03 |
2015-09-11 |
Merck Sharp & Dohme |
|
|
GB0919054D0
(en)
|
2009-10-30 |
2009-12-16 |
Isis Innovation |
Treatment of obesity
|
|
EP2504028A4
(en)
|
2009-11-24 |
2014-04-09 |
Amplimmune Inc |
SIMULTANEOUS INHIBITION OF PD-L1 / PD-L2
|
|
US20130089554A1
(en)
|
2009-12-29 |
2013-04-11 |
Emergent Product Development Seattle, Llc |
RON Binding Constructs and Methods of Use Thereof
|
|
CN103649088B
(zh)
*
|
2011-08-30 |
2016-05-11 |
沃克哈特有限公司 |
1, 6- 二氮杂双环[3, 2, 1]辛- 7- 酮衍生物及其在治疗细菌感染中的用途
|
|
BR112014003476A2
(pt)
|
2011-09-13 |
2017-03-01 |
Wockhardt Ltd |
compostos contendo nitrogênio e seu uso
|
|
US20130108641A1
(en)
|
2011-09-14 |
2013-05-02 |
Sanofi |
Anti-gitr antibodies
|
|
BR112014012819B1
(pt)
|
2011-11-28 |
2022-08-16 |
Merck Patent Gmbh |
Anticorpo anti-pd-l1 ou fragmento de ligação ao antígeno do mesmo e composição
|
|
US8796257B2
(en)
|
2011-12-02 |
2014-08-05 |
Naeja Pharmaceutical Inc. |
Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors
|
|
US9025112B2
(en)
|
2012-02-02 |
2015-05-05 |
Apple Inc. |
Display with color mixing prevention structures
|
|
EP2814483A2
(en)
|
2012-02-15 |
2014-12-24 |
Rempex Pharmaceuticals, Inc. |
Methods of treating bacterial infections
|
|
TW201343645A
(zh)
|
2012-03-30 |
2013-11-01 |
Cubist Pharm Inc |
1,3,4-□二唑及1,3,4-噻二唑β-內醯胺酶抑制劑
|
|
JP2015512419A
(ja)
|
2012-03-30 |
2015-04-27 |
キュービスト ファーマシューティカルズ, インコーポレイテッド |
イソオキザゾールβ−ラクタマーゼ阻害剤
|
|
AR090539A1
(es)
|
2012-04-02 |
2014-11-19 |
Astrazeneca Ab |
COMPUESTOS INHIBIDORES DE b LACTAMASA
|
|
AR091649A1
(es)
|
2012-07-02 |
2015-02-18 |
Bristol Myers Squibb Co |
Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
|
|
ES2672100T3
(es)
|
2012-08-25 |
2018-06-12 |
Wockhardt Limited |
Derivados de 1,6-diazabiciclo[3,2,1]octano-7-ona y su uso en el tratamiento de infecciones bacterianas
|
|
WO2014141132A1
(en)
|
2013-03-14 |
2014-09-18 |
Naeja Pharmaceutical Inc. |
NEW HETEROCYCLIC COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS AND β-LACTAMASE INHIBITORS
|
|
WO2015052682A1
(en)
*
|
2013-10-11 |
2015-04-16 |
Wockhardt Limited |
Nitrogen containing compounds and their use
|
|
WO2016116788A1
(en)
*
|
2015-01-24 |
2016-07-28 |
Wockhardt Limited |
Nitrogen containing bicyclic compounds and their use in treatment of bacterial infections
|
|
EP3277277B1
(en)
*
|
2015-04-03 |
2021-01-06 |
Mutabilis |
Heterocyclic compounds and their use in preventing or treating bacterial infections
|
|
EP3075381A1
(en)
*
|
2015-04-03 |
2016-10-05 |
Mutabilis |
Heterocyclic compounds and their use in preventing or treating bacterial infections
|
|
JOP20190061A1
(ar)
|
2016-09-28 |
2019-03-26 |
Novartis Ag |
مثبطات بيتا-لاكتاماز
|