JP2019529417A5 - - Google Patents
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- Publication number
- JP2019529417A5 JP2019529417A5 JP2019514742A JP2019514742A JP2019529417A5 JP 2019529417 A5 JP2019529417 A5 JP 2019529417A5 JP 2019514742 A JP2019514742 A JP 2019514742A JP 2019514742 A JP2019514742 A JP 2019514742A JP 2019529417 A5 JP2019529417 A5 JP 2019529417A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cancer
- peptides
- hpv
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 16
- 108090000765 processed proteins & peptides Proteins 0.000 claims 14
- 210000001744 T-lymphocyte Anatomy 0.000 claims 13
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 241000701806 Human papillomavirus Species 0.000 claims 7
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 7
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 210000003819 peripheral blood mononuclear cell Anatomy 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 241000341655 Human papillomavirus type 16 Species 0.000 claims 3
- 108090000172 Interleukin-15 Proteins 0.000 claims 3
- 108090001005 Interleukin-6 Proteins 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 230000004936 stimulating effect Effects 0.000 claims 3
- 230000000638 stimulation Effects 0.000 claims 3
- 108010002586 Interleukin-7 Proteins 0.000 claims 2
- 108010063738 Interleukins Proteins 0.000 claims 2
- 102000015696 Interleukins Human genes 0.000 claims 2
- 229940047122 interleukins Drugs 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 206010061424 Anal cancer Diseases 0.000 claims 1
- 208000007860 Anus Neoplasms Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010058314 Dysplasia Diseases 0.000 claims 1
- 206010023825 Laryngeal cancer Diseases 0.000 claims 1
- 206010023849 Laryngeal papilloma Diseases 0.000 claims 1
- 208000032271 Malignant tumor of penis Diseases 0.000 claims 1
- 208000001894 Nasopharyngeal Neoplasms Diseases 0.000 claims 1
- 206010061306 Nasopharyngeal cancer Diseases 0.000 claims 1
- 206010031096 Oropharyngeal cancer Diseases 0.000 claims 1
- 206010057444 Oropharyngeal neoplasm Diseases 0.000 claims 1
- 208000009608 Papillomavirus Infections Diseases 0.000 claims 1
- 208000002471 Penile Neoplasms Diseases 0.000 claims 1
- 206010034299 Penile cancer Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 201000011165 anus cancer Diseases 0.000 claims 1
- 210000003969 blast cell Anatomy 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 206010023841 laryngeal neoplasm Diseases 0.000 claims 1
- 208000009000 laryngeal papillomatosis Diseases 0.000 claims 1
- 201000006958 oropharynx cancer Diseases 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 206010046885 vaginal cancer Diseases 0.000 claims 1
- 208000013139 vaginal neoplasm Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662395440P | 2016-09-16 | 2016-09-16 | |
| US62/395,440 | 2016-09-16 | ||
| US15/331,659 | 2016-10-21 | ||
| US15/331,659 US9642906B2 (en) | 2016-09-16 | 2016-10-21 | Generation of HPV-specific T-cells |
| PCT/EP2017/073274 WO2018050818A1 (en) | 2016-09-16 | 2017-09-15 | Generation of hpv-specific t-cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019529417A JP2019529417A (ja) | 2019-10-17 |
| JP2019529417A5 true JP2019529417A5 (https=) | 2020-10-08 |
Family
ID=57885783
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514742A Pending JP2019529417A (ja) | 2016-09-16 | 2017-09-15 | Ｈｐｖ特異的ｔ細胞の生成 |
| JP2020541775A Pending JP2021511805A (ja) | 2016-09-16 | 2019-01-31 | Ｈｐｖ特異的なｔ細胞の生成 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020541775A Pending JP2021511805A (ja) | 2016-09-16 | 2019-01-31 | Ｈｐｖ特異的なｔ細胞の生成 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US9642906B2 (https=) |
| EP (2) | EP3512936B1 (https=) |
| JP (2) | JP2019529417A (https=) |
| KR (1) | KR20190071689A (https=) |
| CN (2) | CN109996869A (https=) |
| AU (1) | AU2017326601A1 (https=) |
| CA (2) | CA3036747A1 (https=) |
| ES (1) | ES2876152T3 (https=) |
| SG (1) | SG11202007187TA (https=) |
| TW (2) | TW201814040A (https=) |
| WO (2) | WO2018050818A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| CN108289913A (zh) | 2015-10-30 | 2018-07-17 | 儿童国家医疗中心 | 从未致敏t细胞群体产生hpv抗原特异性t细胞 |
| EP3439675A4 (en) | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY |
| US9642906B2 (en) | 2016-09-16 | 2017-05-09 | Baylor College Of Medicine | Generation of HPV-specific T-cells |
| US11649288B2 (en) | 2017-02-07 | 2023-05-16 | Seattle Children's Hospital | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| JP2020537515A (ja) | 2017-10-03 | 2020-12-24 | ジュノー セラピューティクス インコーポレイテッド | Ｈｐｖ特異的結合分子 |
| US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
| US12312416B2 (en) | 2018-02-06 | 2025-05-27 | Seattle Children's Hospital | Fluorescein-specific cars exhibiting optimal t cell function against FL-PLE labelled tumors |
| WO2019164970A1 (en) * | 2018-02-20 | 2019-08-29 | Emory University | Hpv proteins, antibodies, and uses in managing abnormal epithelial cell growth |
| AU2019225174B2 (en) | 2018-02-23 | 2025-11-20 | Endocyte, Inc. | Sequencing method for CAR T cell therapy |
| WO2019196088A1 (en) * | 2018-04-13 | 2019-10-17 | Syz Cell Therapy Co. | Methods of obtaining tumor-specific t cell receptors |
| GB201821207D0 (en) | 2018-12-24 | 2019-02-06 | Tcer Ab | Immunotherapy therapy |
| US12404331B2 (en) | 2019-04-19 | 2025-09-02 | Tcrcure Biopharma Corp. | Anti-PD-1 antibodies and uses thereof |
| CN115210252A (zh) | 2020-02-04 | 2022-10-18 | 西雅图儿童医院（Dba西雅图儿童研究所） | 抗二硝基苯酚的嵌合抗原受体 |
| EP4100051A2 (en) * | 2020-02-07 | 2022-12-14 | ISA Pharmaceuticals B.V. | Treatment of hpv-related diseases |
| WO2021221927A1 (en) | 2020-04-27 | 2021-11-04 | Parsons Corporation | Narrowband iq signal obfuscation |
| CN117529551A (zh) | 2021-04-27 | 2024-02-06 | 贝勒医学院 | 表达嵌合抗原受体的病毒特异性免疫细胞 |
| CN114409744B (zh) * | 2022-03-29 | 2022-10-04 | 深圳吉诺因生物科技有限公司 | Hpv抗原表位及其鉴定方法、应用 |
| EP4605422A2 (en) | 2022-10-20 | 2025-08-27 | Repertoire Immune Medicines, Inc. | Cd8 t cell targeted il2 |
| CN120173140A (zh) * | 2025-03-25 | 2025-06-20 | 陕西向善细胞生物科技有限公司 | 特异性靶向性清除高危型hpv病毒感染的c-dc树突状细胞白蛋白悬液及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2292619T3 (es) | 2000-09-15 | 2008-03-16 | Ortho-Mcneil Pharmaceutical, Inc. | Composiciones y metodos para inducir respuestas citologicas especificas de la celula t. |
| EP2468763B1 (en) | 2007-05-31 | 2014-06-18 | Academisch Ziekenhuis Leiden h.o.d.n. LUMC | HPV epitopes targeted by T cells infiltrating cervical malignancies for use in vaccines |
| CN102625832A (zh) * | 2009-08-24 | 2012-08-01 | 贝勒医学院 | 产生对多种肿瘤抗原或多种病毒特异的ctl细胞系 |
| KR101749195B1 (ko) * | 2011-12-12 | 2017-06-20 | 셀 메디카 리미티드 | T 세포들을 증식시키는 방법 |
| WO2015112626A1 (en) * | 2014-01-21 | 2015-07-30 | June Carl H | Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules |
| US9642906B2 (en) | 2016-09-16 | 2017-05-09 | Baylor College Of Medicine | Generation of HPV-specific T-cells |
| JP7002769B2 (ja) | 2016-09-16 | 2022-02-04 | ベイラー カレッジ オブ メディスン | ウイルス特異的ｔ細胞の活性化および拡大のためのプラットフォーム |
-
2016
- 2016-10-21 US US15/331,659 patent/US9642906B2/en active Active
-
2017
- 2017-09-15 EP EP17772645.2A patent/EP3512936B1/en active Active
- 2017-09-15 WO PCT/EP2017/073274 patent/WO2018050818A1/en not_active Ceased
- 2017-09-15 JP JP2019514742A patent/JP2019529417A/ja active Pending
- 2017-09-15 KR KR1020197009766A patent/KR20190071689A/ko not_active Ceased
- 2017-09-15 TW TW106131752A patent/TW201814040A/zh unknown
- 2017-09-15 CN CN201780071272.2A patent/CN109996869A/zh active Pending
- 2017-09-15 CA CA3036747A patent/CA3036747A1/en not_active Abandoned
- 2017-09-15 ES ES17772645T patent/ES2876152T3/es active Active
- 2017-09-15 US US16/333,597 patent/US11590218B2/en active Active
- 2017-09-15 AU AU2017326601A patent/AU2017326601A1/en not_active Abandoned
-
2018
- 2018-01-31 US US15/885,197 patent/US10500265B2/en active Active
-
2019
- 2019-01-31 SG SG11202007187TA patent/SG11202007187TA/en unknown
- 2019-01-31 TW TW108103877A patent/TW201934748A/zh unknown
- 2019-01-31 JP JP2020541775A patent/JP2021511805A/ja active Pending
- 2019-01-31 US US16/966,582 patent/US20210077612A1/en not_active Abandoned
- 2019-01-31 CN CN201980024303.8A patent/CN111936619A/zh active Pending
- 2019-01-31 EP EP19702862.4A patent/EP3746548A1/en active Pending
- 2019-01-31 CA CA3089667A patent/CA3089667A1/en not_active Abandoned
- 2019-01-31 WO PCT/EP2019/052328 patent/WO2019149801A1/en not_active Ceased
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