JP2019528753A5 - - Google Patents
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- JP2019528753A5 JP2019528753A5 JP2019516383A JP2019516383A JP2019528753A5 JP 2019528753 A5 JP2019528753 A5 JP 2019528753A5 JP 2019516383 A JP2019516383 A JP 2019516383A JP 2019516383 A JP2019516383 A JP 2019516383A JP 2019528753 A5 JP2019528753 A5 JP 2019528753A5
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- JP
- Japan
- Prior art keywords
- item
- items
- vaccinia virus
- oncolytic vaccinia
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662397523P | 2016-09-21 | 2016-09-21 | |
| US62/397,523 | 2016-09-21 | ||
| PCT/US2017/052746 WO2018057755A1 (en) | 2016-09-21 | 2017-09-21 | High mobility group box i mutant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019528753A JP2019528753A (ja) | 2019-10-17 |
| JP2019528753A5 true JP2019528753A5 (enExample) | 2020-11-12 |
Family
ID=61691108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019516383A Pending JP2019528753A (ja) | 2016-09-21 | 2017-09-21 | 高移動度グループboxi突然変異体 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11065286B2 (enExample) |
| EP (1) | EP3515419A4 (enExample) |
| JP (1) | JP2019528753A (enExample) |
| KR (1) | KR20190059297A (enExample) |
| CN (1) | CN110022867A (enExample) |
| AU (2) | AU2017332367B2 (enExample) |
| WO (1) | WO2018057755A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016144564A2 (en) | 2015-02-25 | 2016-09-15 | Memorial Sloan-Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
| CN107847534B (zh) | 2015-04-17 | 2022-10-04 | 纪念斯隆凯特琳癌症中心 | Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用 |
| IL261321B2 (en) | 2016-02-25 | 2023-12-01 | Memorial Sloan Kettering Cancer Center | Recombinant MVA or MVADELE3L expressing human FLT3L and their use as immunotherapeutic agents against solid tumors |
| SG11201807051VA (en) | 2016-02-25 | 2018-09-27 | Memorial Sloan Kettering Cancer Center | Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human flt3l or gm-csf for cancer immunotherapy |
| CN110431228B (zh) | 2016-11-02 | 2024-04-02 | 戴维·埃文斯 | 合成嵌合痘病毒 |
| WO2018209315A1 (en) | 2017-05-12 | 2018-11-15 | Memorial Sloan Kettering Cancer Center | Vaccinia virus mutants useful for cancer immunotherapy |
| JP7551496B2 (ja) | 2017-10-31 | 2024-09-17 | カリヴィル イムノセラピューティクス, インコーポレイテッド | 全身送達のためのプラットフォーム腫瘍溶解性ベクター |
| CN109913422A (zh) * | 2017-12-13 | 2019-06-21 | 苏州康聚生物科技有限公司 | 一种包含肿瘤抗原识别受体的免疫细胞及其应用 |
| CN111936622B (zh) * | 2018-01-19 | 2024-05-28 | 可隆生命科学株式会社 | 重组痘苗病毒和包含其的药物组合物 |
| JP2021522784A (ja) * | 2018-05-02 | 2021-09-02 | トニックス ファーマ ホールディングス リミテッド | 合成キメラワクシニアウイルス |
| CN116162654A (zh) | 2018-09-15 | 2023-05-26 | 纪念斯隆凯特琳癌症中心 | 用于癌症免疫疗法的重组痘病毒 |
| KR102661908B1 (ko) * | 2019-08-29 | 2024-04-29 | 주식회사 바이오녹스 | 백시니아 바이러스 및 과립백혈구 형성 억제제를 유효성분으로 포함하는 암 치료용 약학 조성물 |
| WO2022109133A1 (en) | 2020-11-19 | 2022-05-27 | Kalivir Immunotherapeutics, Inc. | Oncolytic immunotherapy by tumor micro-environment remodeling |
| WO2022232375A1 (en) | 2021-04-30 | 2022-11-03 | Kalivir Immunotherapeutics, Inc. | Oncolytic viruses for modified mhc expression |
| EP4604982A2 (en) * | 2022-10-19 | 2025-08-27 | KaliVir Immunotherapeutics, Inc. | Nucleic acids encoding tgf-beta inhibitor and il-12 and uses thereof |
| WO2025184411A1 (en) | 2024-02-27 | 2025-09-04 | Calidi Biotherapeutics (Nevada), Inc. | Serum-resistant eev viruses and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003258168B2 (en) | 2002-08-12 | 2009-10-29 | Sillajen Biotherapeutics, Inc. | Methods and compositions concerning poxviruses and cancer |
| GB0226251D0 (en) * | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
| CA2882022A1 (en) * | 2003-09-11 | 2005-03-24 | Walter Newman | Monoclonal antibodies against hmgb1 |
| WO2009054996A2 (en) * | 2007-10-25 | 2009-04-30 | Genelux Corporation | Systems and methods for viral therapy |
| US8313896B2 (en) * | 2008-04-04 | 2012-11-20 | The General Hospital Corporation | Oncolytic herpes simplex virus immunotherapy in the treatment of brain cancer |
| JP5686814B2 (ja) | 2010-09-17 | 2015-03-18 | 独立行政法人科学技術振興機構 | Hmgbタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法 |
| WO2012142529A2 (en) | 2011-04-15 | 2012-10-18 | Genelux Corporation | Clonal strains of attenuated vaccinia viruses and methods of use thereof |
| DK2703487T3 (en) * | 2011-04-26 | 2018-09-10 | Genomix Co Ltd | TIME TO INDUCTION Tissue Regeneration and its Use |
| FI20115914L (fi) | 2011-09-16 | 2013-03-17 | Oncos Therapeutics Ltd | Muunnettu onkolyyttinen virus |
| SMT202400047T1 (it) * | 2013-08-22 | 2024-03-13 | Univ Pittsburgh Commonwealth Sys Higher Education | Terapie immuno-oncolitiche |
-
2017
- 2017-09-21 JP JP2019516383A patent/JP2019528753A/ja active Pending
- 2017-09-21 AU AU2017332367A patent/AU2017332367B2/en active Active
- 2017-09-21 KR KR1020197011336A patent/KR20190059297A/ko not_active Withdrawn
- 2017-09-21 WO PCT/US2017/052746 patent/WO2018057755A1/en not_active Ceased
- 2017-09-21 US US16/335,515 patent/US11065286B2/en active Active
- 2017-09-21 EP EP17853903.7A patent/EP3515419A4/en active Pending
- 2017-09-21 CN CN201780071852.1A patent/CN110022867A/zh active Pending
-
2021
- 2021-06-01 US US17/335,430 patent/US20210338754A1/en active Pending
-
2022
- 2022-01-12 AU AU2022200169A patent/AU2022200169B2/en not_active Expired - Fee Related
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