JP2019528753A5 - - Google Patents

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Publication number
JP2019528753A5
JP2019528753A5 JP2019516383A JP2019516383A JP2019528753A5 JP 2019528753 A5 JP2019528753 A5 JP 2019528753A5 JP 2019516383 A JP2019516383 A JP 2019516383A JP 2019516383 A JP2019516383 A JP 2019516383A JP 2019528753 A5 JP2019528753 A5 JP 2019528753A5
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JP
Japan
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item
items
vaccinia virus
oncolytic vaccinia
nucleic acid
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Pending
Application number
JP2019516383A
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English (en)
Japanese (ja)
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JP2019528753A (ja
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Priority claimed from PCT/US2017/052746 external-priority patent/WO2018057755A1/en
Publication of JP2019528753A publication Critical patent/JP2019528753A/ja
Publication of JP2019528753A5 publication Critical patent/JP2019528753A5/ja
Pending legal-status Critical Current

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JP2019516383A 2016-09-21 2017-09-21 高移動度グループboxi突然変異体 Pending JP2019528753A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662397523P 2016-09-21 2016-09-21
US62/397,523 2016-09-21
PCT/US2017/052746 WO2018057755A1 (en) 2016-09-21 2017-09-21 High mobility group box i mutant

Publications (2)

Publication Number Publication Date
JP2019528753A JP2019528753A (ja) 2019-10-17
JP2019528753A5 true JP2019528753A5 (enExample) 2020-11-12

Family

ID=61691108

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019516383A Pending JP2019528753A (ja) 2016-09-21 2017-09-21 高移動度グループboxi突然変異体

Country Status (7)

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US (2) US11065286B2 (enExample)
EP (1) EP3515419A4 (enExample)
JP (1) JP2019528753A (enExample)
KR (1) KR20190059297A (enExample)
CN (1) CN110022867A (enExample)
AU (2) AU2017332367B2 (enExample)
WO (1) WO2018057755A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016144564A2 (en) 2015-02-25 2016-09-15 Memorial Sloan-Kettering Cancer Center Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors
CN107847534B (zh) 2015-04-17 2022-10-04 纪念斯隆凯特琳癌症中心 Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用
IL261321B2 (en) 2016-02-25 2023-12-01 Memorial Sloan Kettering Cancer Center Recombinant MVA or MVADELE3L expressing human FLT3L and their use as immunotherapeutic agents against solid tumors
SG11201807051VA (en) 2016-02-25 2018-09-27 Memorial Sloan Kettering Cancer Center Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human flt3l or gm-csf for cancer immunotherapy
CN110431228B (zh) 2016-11-02 2024-04-02 戴维·埃文斯 合成嵌合痘病毒
WO2018209315A1 (en) 2017-05-12 2018-11-15 Memorial Sloan Kettering Cancer Center Vaccinia virus mutants useful for cancer immunotherapy
JP7551496B2 (ja) 2017-10-31 2024-09-17 カリヴィル イムノセラピューティクス, インコーポレイテッド 全身送達のためのプラットフォーム腫瘍溶解性ベクター
CN109913422A (zh) * 2017-12-13 2019-06-21 苏州康聚生物科技有限公司 一种包含肿瘤抗原识别受体的免疫细胞及其应用
CN111936622B (zh) * 2018-01-19 2024-05-28 可隆生命科学株式会社 重组痘苗病毒和包含其的药物组合物
JP2021522784A (ja) * 2018-05-02 2021-09-02 トニックス ファーマ ホールディングス リミテッド 合成キメラワクシニアウイルス
CN116162654A (zh) 2018-09-15 2023-05-26 纪念斯隆凯特琳癌症中心 用于癌症免疫疗法的重组痘病毒
KR102661908B1 (ko) * 2019-08-29 2024-04-29 주식회사 바이오녹스 백시니아 바이러스 및 과립백혈구 형성 억제제를 유효성분으로 포함하는 암 치료용 약학 조성물
WO2022109133A1 (en) 2020-11-19 2022-05-27 Kalivir Immunotherapeutics, Inc. Oncolytic immunotherapy by tumor micro-environment remodeling
WO2022232375A1 (en) 2021-04-30 2022-11-03 Kalivir Immunotherapeutics, Inc. Oncolytic viruses for modified mhc expression
EP4604982A2 (en) * 2022-10-19 2025-08-27 KaliVir Immunotherapeutics, Inc. Nucleic acids encoding tgf-beta inhibitor and il-12 and uses thereof
WO2025184411A1 (en) 2024-02-27 2025-09-04 Calidi Biotherapeutics (Nevada), Inc. Serum-resistant eev viruses and uses thereof

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
AU2003258168B2 (en) 2002-08-12 2009-10-29 Sillajen Biotherapeutics, Inc. Methods and compositions concerning poxviruses and cancer
GB0226251D0 (en) * 2002-11-11 2002-12-18 San Raffaele Centro Fond Acetylated protein
CA2882022A1 (en) * 2003-09-11 2005-03-24 Walter Newman Monoclonal antibodies against hmgb1
WO2009054996A2 (en) * 2007-10-25 2009-04-30 Genelux Corporation Systems and methods for viral therapy
US8313896B2 (en) * 2008-04-04 2012-11-20 The General Hospital Corporation Oncolytic herpes simplex virus immunotherapy in the treatment of brain cancer
JP5686814B2 (ja) 2010-09-17 2015-03-18 独立行政法人科学技術振興機構 Hmgbタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法
WO2012142529A2 (en) 2011-04-15 2012-10-18 Genelux Corporation Clonal strains of attenuated vaccinia viruses and methods of use thereof
DK2703487T3 (en) * 2011-04-26 2018-09-10 Genomix Co Ltd TIME TO INDUCTION Tissue Regeneration and its Use
FI20115914L (fi) 2011-09-16 2013-03-17 Oncos Therapeutics Ltd Muunnettu onkolyyttinen virus
SMT202400047T1 (it) * 2013-08-22 2024-03-13 Univ Pittsburgh Commonwealth Sys Higher Education Terapie immuno-oncolitiche

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