JP2019527600A - 生来の弁機能の保存、補充、および/または置換のための、隆起した弁部分および単腔固定部を備えた心腔人工弁移植 - Google Patents
生来の弁機能の保存、補充、および/または置換のための、隆起した弁部分および単腔固定部を備えた心腔人工弁移植 Download PDFInfo
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2445—Annuloplasty rings in direct contact with the valve annulus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2463—Implants forming part of the valve leaflets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2469—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with resilient valve members, e.g. conical spiral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2478—Passive devices for improving the function of the heart muscle, i.e. devices for reshaping the external surface of the heart, e.g. bags, strips or bands
- A61F2/2487—Devices within the heart chamber, e.g. splints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0048—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
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Abstract
Description
本出願は、2016年8月11日に出願された、HEART CHAMBER PROSTHETIC VALVE IMPLANT WITH STENT,SPRING AND DOME SECTIONSと題する米国仮特許出願第62/373541号、2016年8月11日に出願された、HEART CHAMBER PROSTHETIC VALVE IMPLANT WITH STENT,MESH AND DOME SECTIONSと題する米国仮特許出願第62/373560号、および2016年8月11日に出願された、HEART CHAMBER PROSTHETIC VALVE IMPLANT WITH ELEVATED VALVE SECTIONと題する米国特許仮出願第62/373551号の利益を主張し、その全体が参照により本明細書に組み込まれる。
連邦政府資金による研究開発の記載
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Claims (27)
- 環状平面を含む弁輪および弁尖を有する生来の弁と流体連通している心腔内での拡張移植のための装置であって、前記装置は、
前記環状平面上に少なくとも部分的に配置された下面を含む基部であって、前記下面は、前記基部の下面および環状平面の上方に離間して配置された隆起部を含む、基部と、
前記装置が拡張され移植されたときに圧力がかかり前記心腔ルーフと摩擦係合する心房ドーム部分と、
前記基部と、前記基部および頂部と動作可能に接続された前記心房ドーム部分とに、動作可能に取り付けられている、中間部と、
下面を含む中央シリンダ弁支持体であって、前記中央シリンダ弁支持体は、前記基部の前記隆起部に動作可能に取り付けられ、その中に動作可能に取り付けられた少なくとも1つの人工弁尖を含み、前記中央シリンダ弁支持体の前記下面は前記基部の前記下面および前記環状平面の上方に離間している、中央シリンダ弁支持体と、
を備える、装置。 - 前記中央シリンダ弁支持体の前記下面に、前記中央シリンダ弁支持体内に取り付けられた前記少なくとも1つの人工弁尖をさらに備える、請求項1に記載の装置。
- 前記中央シリンダ弁支持体の前記下面の上方に位置する場所に、前記中央シリンダ弁支持体内に取り付けられた前記少なくとも1つの人工弁尖をさらに備える、請求項1に記載の装置。
- 前記心腔が左心房を含み、前記生来の弁が生来の弁尖を含む僧帽弁を含む、請求項1に記載の装置。
- 前記生来の弁尖と構造上係合しない、前記拡張され移植された装置をさらに含む、請求項1に記載の装置。
- 前記生来の弁尖を含む生来の僧帽弁と構造上係合しない、前記拡張され移植された装置をさらに含む、請求項4に記載の装置。
- 左心室内に構造上存在しない、前記拡張され移植された装置をさらに備える、請求項4に記載の装置。
- 肺動脈内に構造上存在しない、前記拡張され移植された装置をさらに含む、請求項4に記載の装置。
- 環状平面を含む弁輪および弁尖を有する生来の弁と流体連通している心腔内での拡張移植のための装置であって、前記装置は、
前記環状平面上に少なくとも部分的に配置された下面を含む基部であって、前記下面は、一般に前記弁輪の周りに位置するアパーチャを画定する、基部と、
前記装置が拡張され移植されたときに圧力がかかり前記心腔ルーフと摩擦係合する頂部と、
前記基部と、前記基部および頂部と動作可能に接続された前記心房ドーム部分とに、動作可能に取り付けられている、中間部と、
下面を含む中央シリンダ弁支持体であって、前記中央シリンダ弁支持体の前記下面は、前記基部の前記下面の一部を画定する前記アパーチャと動作可能に接続され、前記中央シリンダ弁支持体はその中に動作可能に取り付けられた少なくとも1つの人工弁尖をさらに備え、前記中央シリンダ弁支持体の前記下面は前記環状平面の下には延びていない、中央シリンダ弁支持体と
を備える、装置。 - 前記中央シリンダ弁支持体の前記下面に、前記中央シリンダ弁支持体内に取り付けられた前記少なくとも1つの人工弁尖をさらに備える、請求項9に記載の装置。
- 前記中央シリンダ弁支持体の前記下面の上方に位置する場所に、前記中央シリンダ弁支持体内に取り付けられた前記少なくとも1つの人工弁尖をさらに備える、請求項9に記載の装置。
- 前記心腔が左心房を含み、前記生来の弁が僧帽弁を含む、請求項9に記載の装置。
- 左心室内に構造上存在しない、前記拡張され移植された装置をさらに備える、請求項12に記載の装置。
- 前記生来の弁尖と構造上係合しない、前記拡張され移植された装置をさらに含む、請求項12に記載の装置。
- 肺動脈内に構造上存在しない、前記拡張され移植された装置をさらに含む、請求項12に記載の装置。
- 環状平面を画定する弁輪を含む心腔内に移植された人工心臓弁装置を用いて患者の少なくとも部分的に機能しなくなった生来の心臓弁の機能を保存するための方法であって、
基部と、頂部と、前記基部と前記頂部との間に動作可能に配置された中間部とを備えた固定構造を含む、収縮可能な人工心臓弁装置を設けるステップと、
隆起部に動作可能に取り付けられた中央シリンダ弁支持体を有する前記基部の下面に隆起部を設けるステップであって、前記中央シリンダ弁支持体はその中に動作可能に取り付けられた人工弁尖を備える、ステップと、
前記人工心臓弁装置を単一の心腔内に拡張して移植するステップであって、前記心腔は、前記機能しなくなった生来の弁によって逆行性の流れから少なくとも部分的に保護され、前記基部の前記下面の少なくとも一部は前記環状平面上に配置され、前記中央シリンダ弁支持体、およびその中に取り付けられた人工弁尖は、前記環状平面の下には延びていない、ステップと、
前記拡張され移植された人工心臓弁装置を用いて、前記少なくとも部分的に機能しなくなった生来の弁の前記残りの正常な生来の機能を保存するステップと
を含む、方法。 - 前記心臓の前記単腔が左心房を含み、前記生来の弁が生来の弁尖を含む僧帽弁である、請求項16に記載の方法。
- 前記拡張され移植された人工心臓弁装置が、前記生来の弁尖を含む僧帽弁に構造上存在しない、もしくは係合しない、または患者の左心室に構造上存在しない、もしくは係合しないことを確実にするステップを含む、請求項17に記載の方法。
- 前記拡張され移植された人工心臓弁装置が肺動脈に構造上存在しない、または係合しないことを確実にするステップをさらに含む、請求項17に記載の方法。
- 環状平面を画定する弁輪を含む心腔内に移植された人工心臓弁装置を用いて患者の少なくとも部分的に機能しなくなった生来の心臓弁の機能を保存および補充するための方法であって、
基部と、頂部と、前記基部と前記頂部との間に動作可能に配置された中間部とを備えた固定構造を含む、収縮可能な人工心臓弁装置を設けるステップと、
隆起部に動作可能に取り付けられた中央シリンダ弁支持体を有する前記基部の下面に隆起部を設けるステップであって、前記中央シリンダ弁支持体はその中に動作可能に取り付けられた人工弁尖を備える、ステップと、
前記人工心臓弁装置を単一の心腔内に拡張して移植するステップであって、前記心腔は、前記機能しなくなった生来の弁によって逆行性の流れから少なくとも部分的に保護され、前記基部の前記下面の少なくとも一部は前記環状平面上に配置され、前記中央シリンダ弁支持体は、前記環状平面の下には延びていない、ステップと、
前記移植された人工心臓弁装置を用いて、前記少なくとも部分的に機能しなくなった生来の弁の前記残りの正常な生来の機能を保存および補充するステップと
を含む、方法。 - 前記心臓の前記単腔が左心房を含み、前記生来の弁が僧帽弁である、請求項20に記載の方法。
- 前記拡張され移植された人工心臓弁装置が、前記生来の弁尖を含む僧帽弁に構造上存在しない、もしくは係合しない、または患者の左心室に構造上存在しない、もしくは係合しないことを確実にするステップをさらに含む、請求項21に記載の方法。
- 前記拡張され移植された人工心臓弁装置が、肺動脈に構造上存在しない、または係合しないことを確実にするステップをさらに含む、請求項22に記載の方法。
- 環状平面を画定する弁輪を含む心腔内に移植された人工心臓弁装置を用いて患者の少なくとも部分的に機能しなくなった生来の心臓弁の残りの生来の機能を保存および補充し、移植された人工心臓弁装置で前記心臓弁の機能を置換するための方法であって、
基部と、頂部と、前記基部と前記頂部との間に動作可能に配置された中間部とを備えた固定構造を含む、収縮可能な人工心臓弁装置を設けるステップと、
隆起部に動作可能に取り付けられた中央シリンダ弁支持体を有する前記基部の下面に隆起部を設けるステップであって、前記中央シリンダ弁支持体はその中に動作可能に取り付けられた人工弁尖を備える、ステップと、
前記人工心臓弁装置を単一の心腔内に拡張して移植するステップであって、前記心腔は、前記機能しなくなった生来の弁によって逆行性の流れから少なくとも部分的に保護され、前記基部の前記下面の少なくとも一部は前記環状平面上に配置され、前記中央シリンダ弁支持体、およびその中に取り付けられた人工弁尖は、前記環状平面の下には延びていない、ステップと、
前記移植された人工心臓弁装置を用いて、前記少なくとも部分的に機能しなくなった生来の弁の前記残りの正常な生来の機能を保存および補充するステップと、
前記生来の弁が正常の生来の機能を提供することをやめたときに、前記生来の弁機能を完全に置換するステップと
を含む、方法。 - 前記心臓の前記単腔が左心房であり、前記生来の弁が前記生来の弁尖を含む僧帽弁である、請求項24に記載の方法。
- 前記拡張され移植された人工心臓弁装置が、前記弁尖を含む僧帽弁または前記患者の左心室に構造上係合しないことを確実するステップをさらに含む、請求項25に記載の方法。
- 前記拡張され移植された人工心臓弁装置が、肺動脈に構造上存在しない、または係合しないことを確実にするステップをさらに含む、請求項25に記載の方法。
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