JP2019527563A5 - - Google Patents
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- Publication number
- JP2019527563A5 JP2019527563A5 JP2019526196A JP2019526196A JP2019527563A5 JP 2019527563 A5 JP2019527563 A5 JP 2019527563A5 JP 2019526196 A JP2019526196 A JP 2019526196A JP 2019526196 A JP2019526196 A JP 2019526196A JP 2019527563 A5 JP2019527563 A5 JP 2019527563A5
- Authority
- JP
- Japan
- Prior art keywords
- mirna
- gene construct
- modified gene
- mir
- target cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662366755P | 2016-07-26 | 2016-07-26 | |
| US62/366,755 | 2016-07-26 | ||
| PCT/US2017/043938 WO2018022749A1 (en) | 2016-07-26 | 2017-07-26 | Spatiotemporal regulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019527563A JP2019527563A (ja) | 2019-10-03 |
| JP2019527563A5 true JP2019527563A5 (https=) | 2020-09-03 |
Family
ID=59523304
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019526195A Pending JP2019521717A (ja) | 2016-07-26 | 2017-07-26 | 遺伝子イレーサー |
| JP2019526196A Pending JP2019527563A (ja) | 2016-07-26 | 2017-07-26 | 時空間調節因子 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019526195A Pending JP2019521717A (ja) | 2016-07-26 | 2017-07-26 | 遺伝子イレーサー |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20190169634A1 (https=) |
| EP (2) | EP3491138A1 (https=) |
| JP (2) | JP2019521717A (https=) |
| KR (2) | KR20190053179A (https=) |
| CN (2) | CN110073000A (https=) |
| AU (2) | AU2017302589A1 (https=) |
| CA (2) | CA3031673A1 (https=) |
| WO (2) | WO2018022747A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11446398B2 (en) | 2016-04-11 | 2022-09-20 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| EP3235908A1 (en) | 2016-04-21 | 2017-10-25 | Ecole Normale Superieure De Lyon | Methods for selectively modulating the activity of distinct subtypes of cells |
| CA3062426A1 (en) | 2017-05-08 | 2018-11-15 | Flagship Pioneering Innovations V, Inc. | Compositions for facilitating membrane fusion and uses thereof |
| SG11202011015QA (en) * | 2018-05-15 | 2020-12-30 | Flagship Pioneering Innovations V Inc | Fusosome compositions and uses thereof |
| WO2019241315A1 (en) | 2018-06-12 | 2019-12-19 | Obsidian Therapeutics, Inc. | Pde5 derived regulatory constructs and methods of use in immunotherapy |
| CN112955174A (zh) | 2018-07-09 | 2021-06-11 | 旗舰先锋创新V股份有限公司 | 融合剂脂质体组合物和其用途 |
| US20210386788A1 (en) | 2018-10-24 | 2021-12-16 | Obsidian Therapeutics, Inc. | Er tunable protein regulation |
| CN113631718A (zh) | 2018-11-14 | 2021-11-09 | 旗舰先锋创新V股份有限公司 | 用于特定隔室货物递送的组合物和方法 |
| WO2021100034A1 (en) * | 2019-11-19 | 2021-05-27 | Protalix Ltd. | Removal of constructs from transformed cells |
| GB202006462D0 (en) * | 2020-05-04 | 2020-06-17 | Mote Res Limited | Modifying genomes with integrase |
| KR20240028975A (ko) | 2021-04-08 | 2024-03-05 | 사나 바이오테크놀로지, 인크. | Cd8-특이적 항체 구조체들 및 이의 조성물 |
| CN121693564A (zh) | 2023-06-26 | 2026-03-17 | 夏威夷大学 | 进化的整合酶和其用于基因组编辑的方法 |
| CN120866333A (zh) * | 2024-04-30 | 2025-10-31 | 深圳市深研生物科技有限公司 | 利用膜蛋白进行细胞分选的方法 |
| CN118813656B (zh) * | 2024-06-19 | 2025-06-03 | 山东大学 | 一种大片段dna级联组装的方法、系统及应用 |
| GB2642222A (en) * | 2024-06-26 | 2026-01-07 | E V A Biosystems Ltd | A gene cassette and uses therefor |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19834430C2 (de) * | 1998-07-30 | 2000-05-31 | Harald Von Melchner | Selbstdeletierende Vektoren für die Krebstherapie |
| US7189506B1 (en) * | 1999-03-03 | 2007-03-13 | Genelabs Technologies, Inc. | DNA binding compound-mediated molecular switch system |
| US20060265771A1 (en) * | 2005-05-17 | 2006-11-23 | Lewis David L | Monitoring microrna expression and function |
| CA2609142C (en) * | 2005-05-27 | 2016-02-09 | Fondazione Centro San Raffaele Del Monte Tabor | Therapeutic gene vectors comprising mirna target sequences |
| WO2006128245A1 (en) * | 2005-06-03 | 2006-12-07 | Southern Adelaide Health Service-Flinders Medical Centre | Targeting cells with altered microrna expression |
| US20070054872A1 (en) * | 2005-08-24 | 2007-03-08 | Mirus Bio Corporation | Regulatable or conditional expression systems |
| WO2008019052A2 (en) * | 2006-08-03 | 2008-02-14 | Numira Biosciences, Inc. | Methods and compositions for identifying biomarkers |
| US20090286242A1 (en) * | 2007-12-10 | 2009-11-19 | Cold Spring Harbor Laboratory | MicroRNA Expression Profiling and Uses Thereof |
| CN102099472A (zh) * | 2008-05-19 | 2011-06-15 | 新加坡科技研究局 | 使基因表达靶向于神经胶质瘤的核酸分子和方法 |
| US20100229254A1 (en) * | 2009-03-04 | 2010-09-09 | Kmita Marie | Method for targeted cell ablation |
| EP3444346B1 (en) * | 2010-04-23 | 2022-07-27 | University of Massachusetts | Aav-based treatment of cholesterol-related disorders |
| WO2012056440A1 (en) * | 2010-10-28 | 2012-05-03 | Nanodoc Ltd. | COMPOSITIONS AND METHODS FOR ACTIVATING EXPRESSION BY A SPECIFIC ENDOGENOUS miRNA |
| CN102719556A (zh) * | 2011-03-29 | 2012-10-10 | 北京五加和分子医学研究所有限公司 | 基于AAV载体的高通量miRNA活性检测方法及其应用 |
| WO2012131048A1 (en) * | 2011-03-31 | 2012-10-04 | Royal College Of Surgeons In Ireland | Treatment and prognosis of solid tumour cancers |
| CN102358901A (zh) * | 2011-11-11 | 2012-02-22 | 天津托普泰克生物科技有限公司 | Has-miR-520e的抗肿瘤用途 |
| EP2684962A1 (en) * | 2012-07-10 | 2014-01-15 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Vector for the selective silencing of a gene in astrocytes |
| CN105144204B (zh) * | 2012-12-13 | 2018-02-27 | 麻省理工学院 | 基于重组酶的逻辑与存储系统 |
| EP2948550A1 (en) * | 2013-01-28 | 2015-12-02 | Council of Scientific & Industrial Research | METHOD FOR INHIBITING TUMOR GROWTH THROUGH RNA-INTERFERENCE USING LIPOSOMALLY ASSOCIATED CDC20 siRNA |
| FR3004463A1 (fr) * | 2013-04-11 | 2014-10-17 | Genethon | Systeme d'expression pour une therapie genique selective |
| CN107073051B (zh) * | 2014-10-21 | 2021-08-24 | 马萨诸塞大学 | 重组aav变体及其用途 |
| JP2016088884A (ja) * | 2014-11-04 | 2016-05-23 | 国立大学法人岐阜大学 | 腫瘍治療用組成物 |
| CN108350445A (zh) | 2015-06-19 | 2018-07-31 | 麻省理工学院 | 肿瘤免疫治疗 |
| WO2017096363A1 (en) * | 2015-12-04 | 2017-06-08 | Board Of Regents, The University Of Texas System | Reporter system for detecting and targeting activated cells |
-
2017
- 2017-07-26 WO PCT/US2017/043931 patent/WO2018022747A1/en not_active Ceased
- 2017-07-26 EP EP17754865.8A patent/EP3491138A1/en not_active Withdrawn
- 2017-07-26 JP JP2019526195A patent/JP2019521717A/ja active Pending
- 2017-07-26 US US16/319,786 patent/US20190169634A1/en not_active Abandoned
- 2017-07-26 CN CN201780057742.XA patent/CN110073000A/zh active Pending
- 2017-07-26 KR KR1020197005575A patent/KR20190053179A/ko not_active Withdrawn
- 2017-07-26 AU AU2017302589A patent/AU2017302589A1/en not_active Abandoned
- 2017-07-26 WO PCT/US2017/043938 patent/WO2018022749A1/en not_active Ceased
- 2017-07-26 KR KR1020197005579A patent/KR20190053180A/ko not_active Ceased
- 2017-07-26 CA CA3031673A patent/CA3031673A1/en not_active Abandoned
- 2017-07-26 CA CA3031670A patent/CA3031670A1/en active Pending
- 2017-07-26 JP JP2019526196A patent/JP2019527563A/ja active Pending
- 2017-07-26 EP EP17749048.9A patent/EP3491137A1/en not_active Withdrawn
- 2017-07-26 AU AU2017302587A patent/AU2017302587A1/en not_active Abandoned
- 2017-07-26 CN CN201780058989.3A patent/CN110088285A/zh active Pending
- 2017-07-26 US US16/319,791 patent/US20190233844A1/en not_active Abandoned
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