JP2019523221A5 - - Google Patents

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Publication number
JP2019523221A5
JP2019523221A5 JP2018561225A JP2018561225A JP2019523221A5 JP 2019523221 A5 JP2019523221 A5 JP 2019523221A5 JP 2018561225 A JP2018561225 A JP 2018561225A JP 2018561225 A JP2018561225 A JP 2018561225A JP 2019523221 A5 JP2019523221 A5 JP 2019523221A5
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JP
Japan
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sequence
antibody
seq
antibody according
amino acid
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JP2018561225A
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English (en)
Japanese (ja)
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JP2019523221A (ja
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Priority claimed from PCT/US2017/034681 external-priority patent/WO2017205742A1/en
Publication of JP2019523221A publication Critical patent/JP2019523221A/ja
Publication of JP2019523221A5 publication Critical patent/JP2019523221A5/ja
Priority to JP2022023569A priority Critical patent/JP7331179B2/ja
Withdrawn legal-status Critical Current

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JP2018561225A 2016-05-27 2017-05-26 抗ｃｄ４０抗体とその使用 Withdrawn JP2019523221A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022023569A JP7331179B2 (ja) 2016-05-27 2022-02-18 抗ｃｄ４０抗体とその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662342417P 2016-05-27 2016-05-27
US62/342,417 2016-05-27
PCT/US2017/034681 WO2017205742A1 (en) 2016-05-27 2017-05-26 Anti-cd40 antibodies and their uses

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022023569A Division JP7331179B2 (ja) 2016-05-27 2022-02-18 抗ｃｄ４０抗体とその使用

Publications (2)

Publication Number Publication Date
JP2019523221A JP2019523221A (ja) 2019-08-22
JP2019523221A5 true JP2019523221A5 (https=) 2020-07-02

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ID=59014833

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JP2018561225A Withdrawn JP2019523221A (ja) 2016-05-27 2017-05-26 抗ｃｄ４０抗体とその使用
JP2022023569A Active JP7331179B2 (ja) 2016-05-27 2022-02-18 抗ｃｄ４０抗体とその使用

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JP2022023569A Active JP7331179B2 (ja) 2016-05-27 2022-02-18 抗ｃｄ４０抗体とその使用

Country Status (35)

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US (8) US10519243B2 (https=)
EP (2) EP3464361B1 (https=)
JP (2) JP2019523221A (https=)
KR (2) KR20220028143A (https=)
CN (1) CN109476750B (https=)
AR (2) AR108611A1 (https=)
AU (1) AU2017271602A1 (https=)
BR (1) BR112018074468A2 (https=)
CA (1) CA3025347A1 (https=)
CL (1) CL2018003366A1 (https=)
CO (1) CO2018012699A2 (https=)
CR (1) CR20180605A (https=)
CY (1) CY1124806T1 (https=)
DO (1) DOP2018000258A (https=)
EC (1) ECSP18094829A (https=)
ES (1) ES2901722T3 (https=)
HR (1) HRP20211882T1 (https=)
HU (1) HUE056670T2 (https=)
IL (1) IL263223B2 (https=)
LT (1) LT3464361T (https=)
MX (1) MX393455B (https=)
MY (1) MY195442A (https=)
NZ (1) NZ748644A (https=)
PE (1) PE20190970A1 (https=)
PH (1) PH12018502456A1 (https=)
PL (1) PL3464361T3 (https=)
PT (1) PT3464361T (https=)
RS (1) RS62726B1 (https=)
RU (1) RU2752049C2 (https=)
SG (2) SG10201914132RA (https=)
SI (1) SI3464361T1 (https=)
SM (1) SMT202100721T1 (https=)
TW (2) TWI814279B (https=)
UA (1) UA123111C2 (https=)
WO (1) WO2017205742A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2214701T3 (en) * 2007-11-01 2016-12-12 Univ Arkansas CONFIGURATIONS AND METHODS FOR IMPROVING THE IMMUNE RESPONSES TO Eimeria
SI3464361T1 (sl) * 2016-05-27 2022-01-31 Abbvie Biotherapeutics Inc. Protitelesa proti CD40 in njihove uporabe
CN112512572B (zh) * 2018-04-20 2024-12-10 礼进生物医药科技（上海）有限公司 抗cd40抗体及其用途
ES3016535T3 (en) 2018-11-23 2025-05-09 Strike Pharma Ab Bi-specific conjugates
BR112021009835A2 (pt) * 2018-11-30 2021-08-17 Jiangsu Hengrui Medicine Co., Ltd. anticorpo anti-cd40, fragmento de ligação ao antígeno e uso farmacêutico dos mesmos
CN111454362B (zh) * 2019-03-04 2021-03-02 北京天广实生物技术股份有限公司 特异结合cd40的抗体及其用途
US10570210B1 (en) * 2019-03-04 2020-02-25 Beijing Mabworks Biotech Co.Ltd Antibodies binding CD40 and uses thereof
EP3947454A1 (en) 2019-03-27 2022-02-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Recombinant proteins with cd40 activating properties
WO2020207470A1 (zh) * 2019-04-10 2020-10-15 南开大学 抗cd40抗体及其用途
GB201910900D0 (en) * 2019-07-31 2019-09-11 Scancell Ltd Modified fc-regions to enhance functional affinity of antibodies and antigen binding fragments thereof
WO2021048135A1 (en) 2019-09-09 2021-03-18 Basilea Pharmaceutica International AG Pharmaceutical combinations comprising a furazanobenzimidazoles and a cd40 agonist for use in the treatment of neoplastic diseases
MX2022003009A (es) * 2019-09-11 2022-06-14 Novartis Ag Metodo para prevenir trastornos asociados a virus humanos en pacientes.
KR20220103957A (ko) * 2019-10-23 2022-07-25 리브젠 바이오파마 홀딩스 리미티드 항-cd40 결합 분자 및 이를 포함하는 이중-특이적 항체
CN115038718B (zh) * 2019-11-08 2024-07-02 山东先声生物制药有限公司 抗人程序性死亡配体-1（pd-l1）的抗体及其用途
KR20220109436A (ko) * 2019-12-03 2022-08-04 에보텍 인터내셔널 게엠베하 인터페론-결합된 항원 결합 단백질 및 이의 용도
GB202008003D0 (en) 2020-05-28 2020-07-15 Quine Medical Ab Anti-CD40 antibody
US20230346966A1 (en) * 2020-07-23 2023-11-02 Dyne Therapeutics, Inc. Muscle-targeting complexes and uses thereof in treating muscle atrophy
CN115403670B (zh) * 2021-05-26 2026-03-10 安徽瀚海博兴生物技术有限公司 抗cd40抗体及其用途
EP4534559A4 (en) * 2022-05-31 2025-11-05 Futuregen Biopharmaceutical Beijing Co Ltd Anti-CD40 antibodies, bispecific anti-PD-L1×CD40 antibodies, and their use
AU2023347072A1 (en) * 2022-09-20 2025-01-02 Currus Biologics Pty Ltd Bispecific polypeptides and uses thereof
AR131856A1 (es) * 2023-02-16 2025-05-07 Sanofi Sa Proteínas de unión a cd40

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444887A (en) 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US5179017A (en) 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4634665A (en) 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4716111A (en) 1982-08-11 1987-12-29 Trustees Of Boston University Process for producing human antibodies
US4510245A (en) 1982-11-18 1985-04-09 Chiron Corporation Adenovirus promoter system
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4968615A (en) 1985-12-18 1990-11-06 Ciba-Geigy Corporation Deoxyribonucleic acid segment from a virus
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5413923A (en) 1989-07-25 1995-05-09 Cell Genesys, Inc. Homologous recombination for universal donor cells and chimeric mammalian hosts
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
EP1690934A3 (en) 1990-01-12 2008-07-30 Abgenix, Inc. Generation of xenogeneic antibodies
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
ATE300615T1 (de) 1990-08-29 2005-08-15 Genpharm Int Transgene mäuse fähig zur produktion heterologer antikörper
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
IE922437A1 (en) 1991-07-25 1993-01-27 Idec Pharma Corp Recombinant antibodies for human therapy
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
ES2341666T3 (es) 1991-12-02 2010-06-24 Medimmune Limited Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos.
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
CA2219361C (en) 1995-04-27 2012-02-28 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP0823941A4 (en) 1995-04-28 2001-09-19 Abgenix Inc HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
US5834597A (en) 1996-05-20 1998-11-10 Protein Design Labs, Inc. Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
US5916771A (en) 1996-10-11 1999-06-29 Abgenix, Inc. Production of a multimeric protein by cell fusion method
EP1500329B1 (en) 1996-12-03 2012-03-21 Amgen Fremont Inc. Human antibodies that specifically bind human TNF alpha
BRPI9809391B8 (pt) 1997-04-14 2021-05-25 Amgen Res Munich Gmbh processo para a produção de um receptor de antígeno anti-humano, anticorpo humano e composição farmacêutica
US6235883B1 (en) 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
AU1728800A (en) 1998-11-18 2000-06-05 Genentech Inc. Antibody variants with higher binding affinity compared to parent antibodies
US6946129B1 (en) * 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
EP1975182A1 (en) 2000-02-01 2008-10-01 PanGenetics B.V. CD40-binding APC-activating molecules
US20030059427A1 (en) * 2000-04-28 2003-03-27 Force Walker R. Isolation and characterization of highly active anti-CD40 antibody
AR039067A1 (es) 2001-11-09 2005-02-09 Pfizer Prod Inc Anticuerpos para cd40
US7217797B2 (en) 2002-10-15 2007-05-15 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
BRPI0417266B8 (pt) * 2003-12-25 2021-05-25 Kyowa Hakko Kirin Co Ltd anticorpo monoclonal, seu uso e composição farmacêutica
WO2005123780A2 (en) 2004-04-09 2005-12-29 Protein Design Labs, Inc. Alteration of fcrn binding affinities or serum half-lives of antibodies by mutagenesis
AU2005271892A1 (en) * 2004-07-10 2006-02-16 Alexion Pharmaceuticals, Inc. Methods for discovering antibodies specific to cancer cells and antibodies discovered thereby
EP1810035A4 (en) 2004-11-10 2010-03-17 Macrogenics Inc GENERATION OF FC ANTIBODY REGIONS FOR EFFECTOR FUNCTION
US20090074711A1 (en) * 2006-09-07 2009-03-19 University Of Southhampton Human therapies using chimeric agonistic anti-human cd40 antibody
KR101456728B1 (ko) * 2006-09-08 2014-10-31 메디뮨 엘엘씨 인간화 항-ｃｄ19 항체, 및 이것의 종양학, 이식 및 자가면역 질환의 치료에서의 용도
CA2701788C (en) * 2007-10-05 2017-06-13 Genentech, Inc. Humanized beta-amyloid antibody for treating ocular diseases
BR112012024713B1 (pt) * 2010-03-31 2021-02-17 Boehringer Ingelheim International Gmbh anticorpo humanizado, seus usos e composição farmacêutica que o compreende
CN113461819B (zh) 2011-04-29 2024-01-02 埃派斯进有限公司 抗-cd40抗体及其使用方法
GB201115280D0 (en) * 2011-09-05 2011-10-19 Alligator Bioscience Ab Antibodies, uses and methods
TW202237660A (zh) * 2012-08-24 2022-10-01 日商中外製藥股份有限公司 FcγRIIb特異性Fc區域變異體
AU2013337903B2 (en) * 2012-10-30 2018-08-16 Apexigen, Inc. Anti-CD40 antibodies and methods of use
ES2699599T3 (es) * 2013-03-15 2019-02-11 Abbvie Biotherapeutics Inc Variantes de Fc
GB201322583D0 (en) * 2013-12-19 2014-02-05 Alligator Bioscience Ab Antibodies
CA2963720C (en) 2014-10-29 2024-05-14 Seattle Genetics, Inc. Dosage and administration of non-fucosylated anti-cd40 antibodies
US10174121B2 (en) * 2015-05-29 2019-01-08 Abbvie, Inc. Anti-CD40 antibodies
BR112018074453A2 (pt) * 2016-05-27 2019-03-19 Abbvie Biotherapeutics Inc. proteínas de ligação biespecíficas ligando uma protéina imunomoduladora e um antígeno tumoral
SI3464361T1 (sl) * 2016-05-27 2022-01-31 Abbvie Biotherapeutics Inc. Protitelesa proti CD40 in njihove uporabe

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